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Journals Europace : European Pacing, Ar...

Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology

https://read.qxmd.com/read/37099638/sudden-cardiac-death-and-atrial-depolarization-in-coronary-artery-disease-authors-reply
#21
JOURNAL ARTICLE
Juha S Perkiömäki, Jenni J Hekkanen, M Juhani Junttila, Heikki V Huikuri
No abstract text is available yet for this article.
April 26, 2023: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://read.qxmd.com/read/37099628/gene-and-variant-specific-efficacy-of-serum-glucocorticoid-regulated-kinase-1-inhibition-in-long-qt-syndrome-types-1-and-2
#22
JOURNAL ARTICLE
Federica Giannetti, Miriam Barbieri, Assad Shiti, Simona Casini, Philip T Sager, Saumya Das, Sabindra Pradhananga, Dinesh Srinivasan, Saranda Nimani, Nicolò Alerni, Julien Louradour, Manuela Mura, Massimiliano Gnecchi, Paul Brink, Manfred Zehender, Gideon Koren, Antonio Zaza, Lia Crotti, Arthur A M Wilde, Peter J Schwartz, Carol Ann Remme, Lior Gepstein, Luca Sala, Katja E Odening
AIMS: Current long QT syndrome (LQTS) therapy, largely based on beta-blockade, does not prevent arrhythmias in all patients; therefore, novel therapies are warranted. Pharmacological inhibition of the serum/glucocorticoid-regulated kinase 1 (SGK1-Inh) has been shown to shorten action potential duration (APD) in LQTS type 3. We aimed to investigate whether SGK1-Inh could similarly shorten APD in LQTS types 1 and 2. METHODS AND RESULTS: Human-induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) and hiPSC-cardiac cell sheets (CCS) were obtained from LQT1 and LQT2 patients; CMs were isolated from transgenic LQT1, LQT2, and wild-type (WT) rabbits...
April 26, 2023: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://read.qxmd.com/read/37097046/ablation-of-atrial-fibrillation-and-dementia-risk-reduction-during-long-term-follow-up-a-nationwide-population-based-study
#23
JOURNAL ARTICLE
Guan-Yi Li, Yun-Yu Chen, Yenn-Jiang Lin, Kuo-Liong Chien, Yu-Cheng Hsieh, Fa-Po Chung, Li-Wei Lo, Shih-Lin Chang, Tze-Fan Chao, Yu-Feng Hu, Chin-Yu Lin, Shih-Ann Chen
AIMS: This study investigated the epidemiological characteristics of new-onset dementia in patients with atrial fibrillation (AF) and the association of catheter ablation with different subtypes of dementia. METHODS AND RESULTS: We conducted a population-based, retrospective cohort study using data from the Taiwan National Health Insurance Research Database. In total, 136 774 patients without a history of dementia were selected after 1:1 propensity score matching based on age (with AF vs...
April 25, 2023: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://read.qxmd.com/read/37096979/catheter-ablation-of-intramural-outflow-tract-premature-ventricular-complexes-a-multicentre-study
#24
JOURNAL ARTICLE
Matthew Hanson, Piotr Futyma, Weeranun Bode, Jackson J Liang, Carlos Tapia, Christian Adams, Łukasz Zarębski, Aleksandra Wrzos, Luis Saenz, Mouhannad Sadek, Daniele Muser, Adrian Baranchuk, Francis Marchlinski, Pasquale Santangeli, Fermin Garcia, Andres Enriquez
AIMS: Ablation of outflow tract ventricular arrhythmias may be limited by a deep intramural location of the arrhythmogenic source. This study evaluates the acute and long-term outcomes of patients undergoing ablation of intramural outflow tract premature ventricular complexes (PVCs). METHODS AND RESULTS: This multicenter series included patients with structurally normal heart or nonischemic cardiomyopathy and intramural outflow tract PVCs defined by: (a) ≥ 2 of the following criteria: (1) earliest endocardial or epicardial activation < 20ms pre-QRS; (2) Similar activation in different chambers; (3) no/transient PVC suppression with ablation at earliest endocardial/epicardial site; or (b) earliest ventricular activation recorded in a septal coronary vein...
April 25, 2023: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://read.qxmd.com/read/37096813/real-world-results-of-oesophageal-protection-from-a-temperature-control-device-during-left-atrial-ablation
#25
JOURNAL ARTICLE
Lisa W M Leung, Pavandeep Toor, Zaki Akhtar, Abhay Bajpai, Anthony Li, Manav Sohal, Mark M Gallagher
No abstract text is available yet for this article.
April 25, 2023: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://read.qxmd.com/read/37084084/the-evaluate-renal-artery-denervation-in-addition-to-catheter-ablation-to-eliminate-atrial-fibrillation-eradicate-af-trial-arrhythmia-suppression-blood-pressure-control-and-potential-interactions
#26
JOURNAL ARTICLE
Jonathan S Steinberg, Nicholas Blount, Dmitry Ponomarev, Vitaly Shabanov, Evgeny Pokushalov, Alexander Romanov
No abstract text is available yet for this article.
April 21, 2023: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://read.qxmd.com/read/37083891/run-baby-run-%C3%A2-but-not-too-fast-rate-control-management-in-atrial-fibrillation-a-claim-for-personalization
#27
JOURNAL ARTICLE
Igor Diemberger, Giuseppe Boriani
No abstract text is available yet for this article.
April 21, 2023: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://read.qxmd.com/read/37083853/a-subtype-electrocardiogram-pattern-on-idiopathic-ventricular-arrhythmias-originating-around-the-pulmonary-right-sinus-discordance-between-electrocardiographic-classification-and-three-dimensional-mapping
#28
JOURNAL ARTICLE
Sixian Weng, Haiyang Xie, Xiaogang Guo, Qi Sun, Fang Wang, Min Tang
No abstract text is available yet for this article.
April 21, 2023: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://read.qxmd.com/read/37083255/copy-number-variation-of-gasdermin-d-gene-is-associated-with-atrial-fibrillation-related-thromboembolic-stroke
#29
JOURNAL ARTICLE
Pang-Shuo Huang, Jen-Fang Cheng, Guan-Wei Li, Eric Y Chuang, Jien-Jiun Chen, Fu-Chun Chiu, Cho-Kai Wu, Yi-Chih Wang, Juey-Jen Hwang, Chia-Ti Tsai
AIMS: Atrial fibrillation (AF) is one of the major causes of ischaemic stroke. In addition to clinical risk evaluated by the CHA2DS2-VASC score, the impact of genetic factors on the risk of AF-related thromboembolic stroke has been largely unknown. We found several copy number variations (CNVs) in novel genes that were associated with thromboembolic stroke risk in our AF patients by genome-wide approach. Among them, the gasdermin D (GSDMD) gene was related to inflammation. We aimed to test whether GSDMD deletion was associated with AF-related stroke...
April 21, 2023: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://read.qxmd.com/read/37083042/ventricular-rate-in-atrial-fibrillation-and-the-risk-of-heart-failure-and-death
#30
JOURNAL ARTICLE
Lucas Malta Westergaard, Amna Alhakak, Rasmus Rørth, Emil L Fosbøl, Søren L Kristensen, Jesper H Svendsen, Claus Graff, Jonas B Nielsen, Gunnar H Gislason, Lars Køber, Christian Torp-Pedersen, Christina J Y Lee, Peter E Weeke
AIMS: While clinical trials have suggested that a high ventricular rate is associated with increased risk of heart failure (HF) and mortality, all-comers studies are warranted. OBJECTIVE: To assess 1-year risk of new-onset diagnosed HF and all-cause mortality among rate-control treated patients presenting with atrial fibrillation (AF) on an electrocardiogram (ECG) according to ventricular rate. METHODS AND RESULTS: ECGs recorded at the Copenhagen General Practitioners Laboratory (2001-15) were used to identify patients with AF...
April 21, 2023: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://read.qxmd.com/read/37083023/relationship-between-epicardial-adipose-tissue-measured-by-computed-tomography-and-premature-ventricular-complexes-originating-from-different-sites
#31
JOURNAL ARTICLE
Junxian Shen, Didi Zhu, Long Chen, Jiehui Cang, Zhen Zhao, Yuqin Ji, Shangshang Liu, Hongyu Miao, Yaowu Liu, Qianxing Zhou, Yanru He, Junyan Cai
AIMS: This study aims to explore the association between the features of epicardial adipose tissue (EAT) in different zones and premature ventricular complexes (PVCs) originating from different sites by computed tomography (CT). METHODS AND RESULTS: A total of 136 patients who underwent radiofrequency ablation for PVCs were incorporated in this study. One hundred and thirty-six matched controls were included in this study using the case-control method (1:1 matching)...
April 21, 2023: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://read.qxmd.com/read/37078691/atrial-fibrillation-can-adversely-impact-heart-failure-with-preserved-ejection-fraction-by-its-association-with-heart-failure-progression-and-mortality-a-post-hoc-propensity-score-matched-analysis-of-the-topcat-americas-trial
#32
JOURNAL ARTICLE
Sanjeev Saksena, April Slee, Andrea Natale, Dhanunjaya R Lakkireddy, Dipen Shah, Luigi Di Biase, Thorsten Lewalter, Rangadham Nagarakanti, Pasquale Santangeli
AIMS: Prevalent atrial fibrillation (AF) is associated with excess cardiovascular (CV) death (D) and hospitalizations (H) in heart failure (HF) with preserved ejection fraction (pEF). We evaluated if it had an independent role in excess CVD in HFpEF and studied its impact on cause-specific mortality and HF morbidity. METHODS AND RESULTS: We used propensity score-matched (PSM) cohorts from the TOPCAT Americas trial to account for confounding by other co-morbidities...
April 20, 2023: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://read.qxmd.com/read/37072340/treatment-of-pathophysiologic-propagation-outside-of-the-pulmonary-veins-in-retreatment-of-atrial-fibrillation-patients-recover-af-study
#33
JOURNAL ARTICLE
Timothy R Betts, Wilson W Good, Lea Melki, Andreas Metzner, Andrew Grace, Atul Verma, Stephen Murray, Simon James, Tom Wong, Lucas V A Boersma, Daniel Steven, Arian Sultan, Sonia Busch, Petr Neužil, Carlo de Asmundis, Justin Lee, Tamás Szili-Török
AIMS: RECOVER AF evaluated the performance of whole-chamber non-contact charge-density mapping to guide the ablation of non-pulmonary vein (PV) targets in persistent atrial fibrillation (AF) patients following either a first or second failed procedure. METHODS AND RESULTS: RECOVER AF was a prospective, non-randomized trial that enrolled patients scheduled for a first or second ablation retreatment for recurrent AF. The PVs were assessed and re-isolated if necessary...
April 19, 2023: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://read.qxmd.com/read/37070604/clinical-implications-of-a-unique-delta-wave-pattern-in-patients-with-left-sided-wolff-parkinson-white
#34
JOURNAL ARTICLE
Omar Meziab, Audrey Dionne, Robert Przybylski, John K Triedman, Edward P Walsh, Douglas Y Mah
No abstract text is available yet for this article.
April 18, 2023: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://read.qxmd.com/read/37068888/electrocardiographic-markers-of-subclinical-atrial-fibrillation-detected-by-implantable-loop-recorder-insights-from-the-loop-study
#35
JOURNAL ARTICLE
Lucas Yixi Xing, Søren Zöga Diederichsen, Søren Højberg, Derk W Krieger, Claus Graff, Morten S Olesen, Jonas Bille Nielsen, Axel Brandes, Lars Køber, Ketil Jørgen Haugan, Jesper Hastrup Svendsen
AIMS: Insights into subclinical atrial fibrillation (AF) development are warranted to inform the strategies of screening and subsequent clinical management upon AF detection. Hence, this study sought to characterize the onset and progression of subclinical AF with respect to 12-lead electrocardiogram (ECG) parameters. METHODS AND RESULTS: We included AF-naïve individuals aged 70-90 years with additional stroke risk factors who underwent implantable loop recorder (ILR) monitoring in the LOOP Study...
April 18, 2023: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://read.qxmd.com/read/37067822/high-power-chargers-for-electric-vehicles-are-they-safe-for-patients-with-pacemakers-and-defibrillators
#36
JOURNAL ARTICLE
Carsten Lennerz, Claudia Schaarschmidt, Patrick Blažek, Katharina Knoll, Marc Kottmaier, Tilko Reents, Felix Bourier, Sarah Lengauer, Miruna Popa, Katharina Wimbauer, Fabian Bahlke, Hannah Krafft, Florian Englert, Lena Friedrich, Heribert Schunkert, Gabriele Hessling, Isabel Deisenhofer, Christof Kolb, Matthew O'Connor
AIMS: Battery electric vehicle (BEV) sales and use are rapidly expanding. Battery electric vehicles, along with their charging stations, are a potential source of electromagnetic interference (EMI) for patients with cardiac implantable electronic devices (CIEDs). The new 'high-power' charging stations have the potential to create strong electromagnetic fields and induce EMI in CIEDs, and their safety has not been evaluated. METHODS AND RESULTS: A total of 130 CIED patients performed 561 charges of four BEVs and a test vehicle (350 kW charge capacity) using high-power charging stations under continuous 6-lead electrocardiogram monitoring...
April 17, 2023: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://read.qxmd.com/read/37061847/genetic-testing-in-children-with-brugada-syndrome-results-from-a-large-prospective-registry
#37
JOURNAL ARTICLE
Luigi Pannone, Antonio Bisignani, Randy Osei, Anaïs Gauthey, Antonio Sorgente, Pasquale Vergara, Cinzia Monaco, Domenico Giovanni Della Rocca, Alvise Del Monte, Antanas Strazdas, Joerelle Mojica, Maysam Al Housari, Vincenzo Miraglia, Sahar Mouram, Gaetano Paparella, Robbert Ramak, Ingrid Overeinder, Gezim Bala, Alexandre Almorad, Erwin Ströker, Gudrun Pappaert, Juan Sieira, Thomy de Ravel, Mark La Meir, Pedro Brugada, Gian Battista Chierchia, Sonia Van Dooren, Carlo de Asmundis
AIMS: A pathogenic/likely pathogenic (P/LP) variant in SCN5A is found in 20-25% of patients with Brugada syndrome (BrS). However, the diagnostic yield and prognosis of gene panel testing in paediatric BrS is unclear. The aim of this study is to define the diagnostic yield and outcomes of SCN5A gene testing with ACMG variant classification in paediatric BrS patients compared with adults. METHODS AND RESULTS: All consecutive patients diagnosed with BrS, between 1992 and 2022, were prospectively enrolled in the UZ Brussel BrS registry...
April 16, 2023: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://read.qxmd.com/read/37061782/ehra-a-20-year-journey-of-success
#38
JOURNAL ARTICLE
David Duncker, Christophe Leclercq, Helmut Pürerfellner, Victor Waldmann, Stefan Simovic, Anthony Li, Priya Bhardwaj, Svya Palayan, Vanessa Meyen, Lauren Tapp, José L Merino
No abstract text is available yet for this article.
April 15, 2023: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://read.qxmd.com/read/37061780/ehra-expert-consensus-document-on-the-management-of-arrhythmias-in-frailty-syndrome-endorsed-by-the-heart-rhythm-society-hrs-asia-pacific-heart-rhythm-society-aphrs-latin-america-heart-rhythm-society-lahrs-and-cardiac-arrhythmia-society-of-southern-africa-cassa
#39
JOURNAL ARTICLE
Irina Savelieva, Stefano Fumagalli, Rose Anne Kenny, Stefan Anker, Athanase Benetos, Giuseppe Boriani, Jared Bunch, Nikolaos Dagres, Sergio Dubner, Laurent Fauchier, Luigi Ferrucci, Carsten Israel, Hooman Kamel, Deirdre A Lane, Gregory Y H Lip, Niccolò Marchionni, Israel Obel, Ken Okumura, Brian Olshansky, Tatjana Potpara, Martin K Stiles, Juan Tamargo, Andrea Ungar, Jedrzej Kosiuk, Torben Bjerregaard Larsen, Borislav Dinov, Heidi Estner, Rodrigue Garcia, Francisco Manuel Moscoso Costa, Rachel Lampert, Yenn-Jiang Lin, Ashley Chin, Heliodoro Antonio Rodriguez, Timo Strandberg, Tomasz Grodzicki
There is an increasing proportion of the general population surviving to old age with significant chronic disease, multi-morbidity, and disability. The prevalence of pre-frail state and frailty syndrome increases exponentially with advancing age and is associated with greater morbidity, disability, hospitalization, institutionalization, mortality, and health care resource use. Frailty represents a global problem, making early identification, evaluation, and treatment to prevent the cascade of events leading from functional decline to disability and death, one of the challenges of geriatric and general medicine...
April 15, 2023: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://read.qxmd.com/read/37050858/multi-centre-prospective-randomized-comparison-of-three-different-substrate-ablation-strategies-for-persistent-atrial-fibrillation
#40
JOURNAL ARTICLE
Kaige Li, Changhao Xu, Xiyao Zhu, Xinhua Wang, Ping Ye, Weifeng Jiang, Shaohui Wu, Kai Xu, Xiangting Li, Ying Wang, Qidong Zheng, Yanzhe Wang, Lihua Leng, Zengtang Zhang, Bing Han, Yu Zhang, Mu Qin, Xu Liu
AIMS: The optimal strategy for persistent atrial fibrillation (PerAF) is poorly defined. We conducted a multicentre, randomized, prospective trial to compare the outcomes of different ablation strategies for PerAF. METHODS AND RESULTS: We enrolled 450 patients and randomly assigned them in a 1:1:1 ratio to undergo pulmonary vein isolation and subsequently undergo the following three different ablation strategies: anatomical guided ablation (ANAT group, n = 150), electrogram guided ablation (EGM group, n = 150), and extensive electro-anatomical guided ablation (EXT group, n = 150)...
April 13, 2023: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
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