E M D Smith, A Aggarwal, J Ainsworth, E Al-Abadi, T Avcin, L Bortey, J Burnham, C Ciurtin, C M Hedrich, S Kamphuis, L Lambert, D M Levy, L Lewandowski, N Maxwell, E Morand, S Ozen, C E Pain, A Ravelli, C Saad Magalhaes, C Pilkington, D Schonenberg-Meinema, C Scott, K Tullus, M W Beresford
OBJECTIVE: To achieve a consensus-based definition of Low Disease Activity (LDA) for use in cSLE trials. METHODS: The International cSLE T2T Task Force, comprising of paediatric rheumatologists/nephrologists, and adult rheumatologists undertook a series of Delphi surveys/consensus meetings to discuss, refine, and vote upon cSLE LDA criteria. RESULTS: The Task Force agreed that LDA should be based upon the adult-SLE Lupus Low Disease Activity State definition (LLDAS), with modifications to make it applicable to cSLE (cLLDAS)...
March 17, 2023: Clinical Immunology: the Official Journal of the Clinical Immunology Society