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Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology

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https://read.qxmd.com/read/30777679/age-related-deterioration-of-saccule-related-neural-function-is-associated-with-decreased-estimated-glomerular-filtration-rate-and-increased-free-thyroxine
#1
Ileok Jung, Su-Hyun Ahn, Juyoung Lee, Sun-Uk Lee, Hui Jong Oh, Hyo-Jung Kim, Jeong-Yoon Choi, Ji-Soo Kim
OBJECTIVE: This study attempted to identify systemic factors for age-related decline in neural function originating from the saccule using cervical vestibular-evoked myogenic potentials (cVEMP) parameters. METHODS: We recruited 129 symptomatic vertiginous patients who did not have known disorder affecting the cVEMP pathway (mean age = 52.4 ± 13.9). The indicators of saccule-related neural function were the sum of normalized cVEMP amplitude (SNA) and the average of p13 latency on both sides (average latency, AL)...
February 12, 2019: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://read.qxmd.com/read/30772764/exploring-the-relationship-between-electrical-impedance-myography-and-quantitative-ultrasound-parameters-in-duchenne-muscular-dystrophy
#2
Bhaskar Roy, Basil T Darras, Craig M Zaidman, Jim S Wu, Kush Kapur, Seward B Rutkove
OBJECTIVES: Quantitative ultrasound (QUS), including grayscale level analysis (GLA) and quantitative backscatter analysis (QBA), and electrical impedance myography (EIM) have been proposed as biomarkers in Duchenne muscular dystrophy (DMD). However, the relationship between these methods has not been assessed. METHODS: QUS values (including GLA and QBA) and several EIM measures were recorded from six muscles in 36 DMD and 29 healthy boys between ages 5 and 13 years at baseline, 6-months, and 12-months...
February 12, 2019: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://read.qxmd.com/read/30770305/eeg-and-meg-source-imaging-for-epilepsy-surgery-a-sobering-22-year-interim-report
#3
EDITORIAL
Chris Plummer
No abstract text is available yet for this article.
February 10, 2019: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://read.qxmd.com/read/30769271/latent-erp-components-of-cognitive-dysfunctions-in-adhd-and-schizophrenia
#4
Juri D Kropotov, Marina V Pronina, Valery A Ponomarev, Yury I Poliakov, Irina V Plotnikova, Andreas Mueller
OBJECTIVE: The main goal was to assess common and specific deficits of cognitive control in (Attention Deficit Hyperactivity Disorder) ADHD and schizophrenia (SZ) using event-related potentials (ERPs). METHOD: Behavioral and EEG data in cued GO/NOGO task were recorded in 132 healthy controls (HC) and age, gender and education matched 63 ADHD adults, and 68 SZ patients. RESULTS: N2d wave in NOGO-GO contrast of ERPs did not differ between the groups while the P3d wave discriminated SZ group from two other groups...
February 10, 2019: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://read.qxmd.com/read/30772237/the-cutaneous-silent-period-an-underutilized-tool-in-clinical-neurophysiology
#5
EDITORIAL
Mariano Serrao
No abstract text is available yet for this article.
February 7, 2019: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://read.qxmd.com/read/30776732/spastic-dystonia-in-stroke-subjects-prevalence-and-features-of-the-neglected-phenomenon-of-the-upper-motor-neuron-syndrome
#6
Carlo Trompetto, Antonio Currà, Luca Puce, Laura Mori, Carlo Serrati, Francesco Fattapposta, Giovanni Abbruzzese, Lucio Marinelli
OBJECTIVE: Spastic dystonia is one of the positive phenomena of the upper motor neuron syndrome (UMNS). It is characterised by the inability to relax a muscle leading to a spontaneous, although stretch-sensitive, tonic contraction. Although spastic dystonia is a recognized cause of muscle hypertonia, its prevalence among hypertonic muscles of stroke subjects has never been investigated. Differently from spasticity, which is an exaggerated stretch reflex, spastic dystonia is viewed as an efferent phenomenon, due to an abnormal central drive to motoneurons...
February 6, 2019: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://read.qxmd.com/read/30772763/detection-of-rem-sleep-behaviour-disorder-by-automated-polysomnography-analysis
#7
Navin Cooray, Fernando Andreotti, Christine Lo, Mkael Symmonds, Michele T M Hu, Maarten De Vos
OBJECTIVE: Evidence suggests Rapid-Eye-Movement (REM) Sleep Behaviour Disorder (RBD) is an early predictor of Parkinson's disease. This study proposes a fully-automated framework for RBD detection consisting of automated sleep staging followed by RBD identification. METHODS: Analysis was assessed using a limited polysomnography montage from 53 participants with RBD and 53 age-matched healthy controls. Sleep stage classification was achieved using a Random Forest (RF) classifier and 156 features extracted from electroencephalogram (EEG), electrooculogram (EOG) and electromyogram (EMG) channels...
February 6, 2019: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://read.qxmd.com/read/30765197/brainstem-avenues-in-parkinson-s-disease-research
#8
EDITORIAL
Matteo Bologna, Alfredo Berardelli
No abstract text is available yet for this article.
February 6, 2019: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://read.qxmd.com/read/30785009/dyshidrosis-is-associated-with-reduced-amplitudes-in-electrically-evoked-pain-related-potentials-in-women-with-fabry-disease
#9
Gabriela Siedler, Ann-Kathrin Káhn, Frank Weidemann, Christoph Wanner, Claudia Sommer, Nurcan Üçeyler
OBJECTIVE: To investigate A-delta fiber conduction in mild to moderate Fabry disease (FD) patients using pain-related evoked potentials (PREP). METHODS: In this case-control study we prospectively investigated 58 patients with mild to moderate FD and compared data with those of healthy controls. Small fiber function (quantitative sensory testing, QST and sympathetic skin response, SSR), morphology (intraepidermal nerve fiber density, IENFD), and electrical conduction (PREP) were assessed and correlated with sweating as major autonomic function disturbed in FD...
February 4, 2019: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://read.qxmd.com/read/30771724/prolonged-cortical-silent-period-is-related-to-poor-fitness-and-fatigue-but-not-tumor-necrosis-factor-in-multiple-sclerosis
#10
Arthur R Chaves, Liam P Kelly, Craig S Moore, Mark Stefanelli, Michelle Ploughman
OBJECTIVE: Poor fitness among people with Multiple Sclerosis (MS) aggravates disease symptoms. Whether low fitness levels accompany brain functioning changes is unknown. METHODS: MS patients (n = 82) completed a graded maximal exercise test, blood was drawn, and transcranial magnetic stimulation determined resting and active motor thresholds, motor evoked potential latency, and cortical silent period (CSP). RESULTS: Sixty-two percent of participants had fitness levels ranked below 10th percentile...
February 4, 2019: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://read.qxmd.com/read/30771726/assessing-the-localization-accuracy-and-clinical-utility-of-electric-and-magnetic-source-imaging-in-children-with-epilepsy
#11
Eleonora Tamilia, Michel AlHilani, Naoaki Tanaka, Melissa Tsuboyama, Jurriaan M Peters, P Ellen Grant, Joseph R Madsen, Steven M Stufflebeam, Phillip L Pearl, Christos Papadelis
OBJECTIVE: To evaluate the accuracy and clinical utility of conventional 21-channel EEG (conv-EEG), 72-channel high-density EEG (HD-EEG) and 306-channel MEG in localizing interictal epileptiform discharges (IEDs). METHODS: Twenty-four children who underwent epilepsy surgery were studied. IEDs on conv-EEG, HD-EEG, MEG and intracranial EEG (iEEG) were localized using equivalent current dipoles and dynamical statistical parametric mapping (dSPM). We compared the localization error (ELoc ) with respect to the ground-truth Irritative Zone (IZ), defined by iEEG sources, between non-invasive modalities and the distance from resection (Dres ) between good- (Engel 1) and poor-outcomes...
January 31, 2019: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://read.qxmd.com/read/30771722/differences-between-flexion-and-extension-synergy-driven-coupling-at-the-elbow-wrist-and-fingers-of-individuals-with-chronic-hemiparetic-stroke
#12
Laura Miller McPherson, Julius P A Dewald
OBJECTIVE: The flexion and extension synergies were quantified at the paretic elbow, forearm, wrist, and finger joints within the same group of participants for the first time. Differences in synergy expression at each of the four joints were examined, as were the ways these differences varied across the joints. METHODS: Twelve post-stroke individuals with chronic moderate-to-severe hemiparesis and six age-matched controls participated. Participants generated isometric shoulder abduction (SABD) and shoulder adduction (SADD) at four submaximal levels to progressively elicit the flexion and extension synergies, respectively...
January 31, 2019: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://read.qxmd.com/read/30745242/preventing-nerve-injury-with-pedicle-screw-testing
#13
EDITORIAL
Marc R Nuwer
No abstract text is available yet for this article.
January 31, 2019: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://read.qxmd.com/read/30785010/neuronal-spiking-activity-highlights-a-gradient-of-epileptogenicity-in-human-tuberous-sclerosis-lesions
#14
Elodie Despouy, Jonathan Curot, Marie Denuelle, Martin Deudon, Jean-Christophe Sol, Jean-Albert Lotterie, Leila Reddy, Lionel G Nowak, Jérémie Pariente, Simon J Thorpe, Luc Valton, Emmanuel J Barbeau
OBJECTIVE: The mechanisms underlying epileptogenicity in tuberous sclerosis complex (TSC) are poorly understood. METHODS: We analysed neuronal spiking activity (84 neurons), fast ripples (FRs), local field potentials and intracranial electroencephalogram during interictal epileptiform discharges (IEDs) in the tuber and perituber of a patient using novel hybrid electrodes equipped with tetrodes. RESULTS: IEDs were recorded in the tuber and perituber...
January 30, 2019: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://read.qxmd.com/read/30769269/widespread-interictal-epileptic-discharge-more-likely-than-focal-discharges-to-unveil-the-seizure-onset-zone-in-eeg-fmri
#15
Tomohiro Yamazoe, Nicolás von Ellenrieder, Hui Ming Khoo, Yao-Hsien Huang, Natalja Zazubovits, François Dubeau, Jean Gotman
OBJECTIVE: We hypothesized that the number of interictal epileptic discharges (IEDs) during scan and their spatial extent are contributing factors in obtaining appropriate activations that reveal the seizure onset zone (SOZ) in EEG-fMRI. METHODS: 157 IED types, each corresponding to one EEG scalp distribution, in 64 consecutive EEG-fMRI studies from 64 patients with refractory localization-related epilepsy were reviewed. To determine reliable activation, we used the threshold corresponding to corrected whole-brain topological false discovery rate (FDR)...
January 30, 2019: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://read.qxmd.com/read/30771723/subthalamic-and-pallidal-oscillatory-activity-in-patients-with-neurodegeneration-with-brain-iron-accumulation-type-i-nbia-i
#16
Julius Huebl, Anahita Poshtiban, Christof Brücke, Sandy Siegert, Antje Bock, Henryk Koziara, Tomasz Kmiec, Rafał Rola, Tomasz Mandat, Andrea A Kühn
OBJECTIVES: Neurodegeneration with Brain Iron Accumulation type I (NBIA-I) is a rare hereditary neurodegenerative disorder with pallidal degeneration leading to disabling generalized dystonia and parkinsonism. Pallidal or subthalamic deep brain stimulation can partially alleviate motor symptoms. Disease-specific patterns of abnormally enhanced oscillatory neuronal activity recorded from the basal ganglia have been described in patients with movement disorders undergoing deep brain stimulation (DBS)...
January 25, 2019: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://read.qxmd.com/read/30769270/cortical-inhibitory-dysfunction-in-epilepsia-partialis-continua-a-high-frequency-oscillation-somatosensory-evoked-potential-study
#17
Angelo Insola, Vincenzo Di Lazzaro, Giovanni Assenza
OBJECTIVE: The pathophysiology of epilepsia partialis continua (EPC) is still unclear, a thalamo-cortical circuit dysfunction has been hypothesized. The aim of present study is the functional evaluation of the thalamo-cortical network in EPC by means of the study of low- and high-frequency somatosensory evoked potentials (LF-SEP and HF-SEP). METHODS: Median LF-SEP and HF-SEP were recorded in 3 patients with EPC and in 2 patients with rolandic lesions without EPC (non-EPC)...
January 25, 2019: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://read.qxmd.com/read/30772238/clinical-utility-and-prospective-of-tms-eeg
#18
REVIEW
Sara Tremblay, Nigel C Rogasch, Isabella Premoli, Daniel M Blumberger, Silvia Casarotto, Robert Chen, Vincenzo Di Lazzaro, Faranak Farzan, Fabio Ferrarelli, Paul B Fitzgerald, Jeanette Hui, Risto J Ilmoniemi, Vasilios K Kimiskidis, Dimitris Kugiumtzis, Pantelis Lioumis, Alvaro Pascual-Leone, Maria Concetta Pellicciari, Tarek Rajji, Gregor Thut, Reza Zomorrodi, Ulf Ziemann, Zafiris J Daskalakis
Concurrent transcranial magnetic stimulation and electroencephalography (TMS-EEG) has emerged as a powerful tool to non-invasively probe brain circuits in humans, allowing for the assessment of several cortical properties such as excitability and connectivity. Over the past decade, this technique has been applied to various clinical populations, enabling the characterization and development of potential TMS-EEG predictors and markers of treatments and of the pathophysiology of brain disorders. The objective of this article is to present a comprehensive review of studies that have used TMS-EEG in clinical populations and to discuss potential clinical applications...
January 19, 2019: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://read.qxmd.com/read/30713001/nerve-ultrasound-as-a-diagnostic-tool-for-sensory-neuronopathy-in-spinocerebellar-ataxia-syndrome
#19
Ruth Leadbetter, Mark Weatherall, Luciana Pelosi
OBJECTIVE: The objective was to assess if nerve ultrasound has a role in diagnosing sensory neuronopathy in spinocerebellar ataxia syndrome (SCA) by examining if proposed diagnostic cut-off criteria of ultrasound in sensory neuronopathy caused by cerebellar ataxia neuropathy vestibular areflexia syndrome (CANVAS) were also discriminatory for SCA-related sensory neuronopathy. METHODS: Optimal diagnostic cut-off criteria for nerve size measured by diagnostic ultrasound were developed in 14 patients with CANVAS and 42 healthy controls using six peripheral nerve sites; and logistic regression and receiver operating characteristic (ROC) curves...
January 19, 2019: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://read.qxmd.com/read/30711894/similarities-and-differences-between-the-interictal-epileptiform-discharges-of-green-spikes-and-red-spikes-zones-of-human-neocortex
#20
Ruggero Serafini
OBJECTIVE: This study looks for differences in the waveforms of interictal epileptiform discharges (IEDs) between cortices expressing only isolated discharges (green-spikes zones) vs those manifesting seizures (red-spikes zones): these can help to understand ictogenesis mechanisms and improve clinical decision in surgical epilepsy. Typical IEDs are triphasic, exhibiting in sequence: a negative-sharp-wave, a positive-baseline-shift and a negative-slow-wave. Negative-slow-waves are thought to reflect neurophysiological inhibition: their features at a focus' edge may reflect peripheral inhibition, a mechanism characterized in experimental models, curbing seizures' spread...
January 19, 2019: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
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