Flávio Henrique Ferreira Galvão, Maria Clara Camargo Traldi, Renata Sandres Souza Araújo, Jose Tadeu Stefano, Luiz Augusto Carneiro D'Albuquerque, Claudia P Oliveira
•In this review, we described different murine models of carcinogenesis: classic models, new transgenic and combined models, that reproduce the key points for HCC and CCA genesis allowing a better understanding of its genetic physiopathological, and environmental abnormalities. •Each model has its advantages, disadvantages, similarities, and differences with the corresponding human disease and should be chosen according to the specificity of the study. Ultimately, those models can also be used for testing new anticancer therapeutic approaches...
2023: Arquivos de Gastroenterologia