Jie Wang, Mengting Li, Nan Nan, Ao Ma, Min Ao, Jinlei Yu, Xiaohang Wang, Kangshun Han, Dae-Jin Yun, Bao Liu, Ning Li, Zheng-Yi Xu
The homolog gene of the Growth Arrest and DNA Damage-inducible 45 (GADD45) in rice functions in the regulation of plant architecture, grain yield, and blast resistance. The Growth Arrest and DNA Damage-inducible 45 (GADD45) family proteins, well-established stress sensors and tumor suppressors in mammals, serve as pivotal regulators of genotoxic stress responses and tumorigenesis. In contrast, the homolog and role of GADD45 in plants have remained unclear. Herein, using forward genetics, we identified an activation tagging mutant AC13 exhibited dwarf characteristics resulting from the loss-of-function of the rice GADD45α homolog, denoted as OsGADD45a1...
March 10, 2024: Plant Cell Reports