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Biological Research for Nursing

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https://read.qxmd.com/read/30764642/associations-of-hormonal-biomarkers-with-mental-health-and-healthy-behaviors-among-mothers-of-very-low-birthweight-infants
#1
June Cho, Xiaogang Su, Diane Holditch-Davis
OBJECTIVES: To examine the concurrent use of self-report questionnaires and hormonal biomarkers, specifically levels of testosterone and cortisol, along with demographic variables and corrected age (CA) in the assessment of mental health and healthy behaviors among mothers of very-low-birthweight (VLBW, BW < 1,500 g) infants at five time points over 2 years post birth. METHOD: Data on 40 mothers from a neonatal intensive care unit of a tertiary medical center in the southeast United States were collected from the medical record, standard questionnaires for the mother (depressive symptoms, perceived stress, anxiety, mental health status, parenting stress, and healthy lifestyle behaviors), and biochemical measurement of maternal testosterone and cortisol using enzyme immunoassay at birth, 40 weeks' postmenstrual age, and 6, 12, and 24 months CA...
February 14, 2019: Biological Research for Nursing
https://read.qxmd.com/read/30722677/serum-albumin-trend-is-a-predictor-of-mortality-in-icu-patients-with-sepsis
#2
Heather Kendall, Eduardo Abreu, An-Lin Cheng
INTRODUCTION: Patients admitted to the hospital with sepsis are 8 times more likely to die than patients with other diagnoses. There is no diagnostic test that clearly identifies the presence of the dysregulated host response that is central to sepsis. Researchers have identified serum albumin as a possible predictor of mortality in a number of critically ill patient populations. However, these studies primarily focus on the levels on admission, neglecting the clinically significant decrease that occurs subsequently...
February 5, 2019: Biological Research for Nursing
https://read.qxmd.com/read/30722675/neonatal-skin-to-skin-contact-implications-for-learning-and-autonomic-nervous-system-function-in-infants-with-congenital-heart-disease
#3
Tondi M Harrison, Chao-Ying Chen, Phyllis Stein, Roger Brown, Jill C Heathcock
BACKGROUND: Infants with complex congenital heart disease (CCHD) often develop neurodevelopmental disabilities. Cognitive abilities are associated with vagally mediated autonomic function. Skin-to-skin contact (SSC) interventions enhance infant neurodevelopment and autonomic function in other high-risk populations. AIM: To examine the effects of a neonatal SSC intervention on learning and autonomic function in 3-month-old infants: infants with CCHD who received neonatal SSC ( n = 10), typically developing (TD) infants ( n = 16), and infants with CCHD without SSC ( n = 10)...
February 5, 2019: Biological Research for Nursing
https://read.qxmd.com/read/30701989/a-pilot-study-using-a-multistaged-integrated-analysis-of-gene-expression-and-methylation-to-evaluate-mechanisms-for-evening-fatigue-in-women-who-received-chemotherapy-for-breast-cancer
#4
Elena Flowers, Annesa Flentje, Jon Levine, Adam Olshen, Marilyn Hammer, Steven Paul, Yvette Conley, Christine Miaskowski, Kord M Kober
CONTEXT: Fatigue is the most common symptom associated with cancer and its treatment. Investigation of molecular mechanisms associated with fatigue may identify new therapeutic targets. OBJECTIVE: The objective of this pilot study was to evaluate the relationships between gene expression and methylation status and evening fatigue severity in women with breast cancer who received chemotherapy. METHODS: Latent class analysis (LCA) was used to identify evening fatigue phenotypes...
January 31, 2019: Biological Research for Nursing
https://read.qxmd.com/read/30700110/genetic-variants-and-the-cortisol-response-in-children-an-exploratory-study
#5
Anne L Ersig, Debra L Schutte, Jennifer Standley, Elizabeth J Leslie, Bridget Zimmerman, Kirsten Hanrahan, Jeffrey C Murray, Ann Marie McCarthy
OBJECTIVE: We examined genomic variation potentially associated with the cortisol stress response in children having a painful medical procedure. DESIGN: Children 4-10 years old having a peripheral intravenous line inserted provided saliva samples for evaluation of the cortisol response as a biological measure of distress: two on the day of the procedure and two at home on a nonstressful day for comparison values. Children and biological parents also provided samples for genotyping of variants with known or suspected association with the cortisol stress response...
January 30, 2019: Biological Research for Nursing
https://read.qxmd.com/read/30585081/glycemic-control-in-insulin-treated-patients-with-type-2-diabetes-empowerment-perceptions-and-diabetes-distress-as-important-determinants
#6
Shi-Yu Chen, Hui-Chun Hsu, Ruey-Hsia Wang, Yau-Jiunn Lee, Chang-Hsun Hsieh
The purpose of this cross-sectional study was to explore the determinants of hemoglobin A1c (HbA1c) levels in insulin-treated patients with Type 2 diabetes mellitus (T2DM) based on demographic and disease characteristics, self-reported regimen adherence factors (adherence in insulin regimen and self-monitoring of blood glucose), and psychosocial factors (decisional balance for insulin injection, health literacy, self-efficacy for insulin injection, diabetes distress, and empowerment perceptions). Via convenience sampling, 255 insulin-treated patients with T2DM were recruited from two endocrinology clinics in Taiwan...
December 25, 2018: Biological Research for Nursing
https://read.qxmd.com/read/30572710/impact-of-yoga-on-inflammatory-biomarkers-a-systematic-review
#7
Dilorom M Djalilova, Paula S Schulz, Ann M Berger, Adam J Case, Kevin A Kupzyk, Alyson C Ross
BACKGROUND: Many chronic conditions, including heart disease, cancer, and rheumatoid arthritis, are associated with underlying chronic inflammatory processes. Literature reviews have analyzed a variety of integrative therapies and their relationships with chronic inflammation. This systematic review is unique in reporting solely on yoga's relationship with inflammation. Its purpose was to synthesize current literature examining the impact of yoga interventions on inflammatory biomarkers in adults with chronic inflammatory-related disorders...
December 20, 2018: Biological Research for Nursing
https://read.qxmd.com/read/30537857/methicillin-resistant-staphylococcus-aureus-and-other-multidrug-resistant-colonizations-infections-in-an-intensive-care-unit-predictive-factors
#8
Elena Ochotorena, Juan José Hernández Morante, Rubén Cañavate, Roberto Andrés Villegas, Inmaculada Viedma
INTRODUCTION AND OBJECTIVES: Methicillin-resistant Staphylococcus aureus (MRSA) is the most prevalent pathogen causing nosocomial infections in hospitals and health centers. This work is an effort to understand the epidemiology of MRSA and other multidrug-resistant pathogens in an intensive care unit (ICU) and to analyze characteristics that might determine the risk of MRSA colonization/infection in this unit. METHOD: An observational, 1-year prospective longitudinal study was conducted to obtain information about MRSA and other multidrug-resistant colonizations/infections...
December 11, 2018: Biological Research for Nursing
https://read.qxmd.com/read/30522333/associations-between-unhealthy-lifestyle-behaviors-and-metabolic-syndrome-by-gender-in-young-adults
#9
Kuei-Man Lin, Jeng-Yuan Chiou, Hsen-Wen Kuo, Jung-Ying Tan, Shu-Hua Ko, Meng-Chih Lee
OBJECTIVE: Unhealthy lifestyle behaviors, such as smoking, drinking, betel-quid chewing, insufficient exercise, and inadequate sleep are significantly correlated with metabolic syndrome (MetS). To further understand this relationship, this study examined the main effect of unhealthy lifestyle behaviors and their interaction on MetS by gender in young adults. METHOD: A cross-sectional study involving 694 young adults from a national survey was performed in which demographic characteristics, unhealthy lifestyle behaviors, anthropometric measurements, and blood chemistry panels were collected during face-to-face interviews...
December 6, 2018: Biological Research for Nursing
https://read.qxmd.com/read/30514103/depressive-symptoms-perceived-stress-and-cortisol-in-school-age-children-with-type-1-diabetes-a-pilot-study
#10
Sara L Davis, Anne-Marie Kaulfers, John E Lochman, S A Morrison, Erica R Pryor, Marti Rice
Despite adequate insulin regimens and concurrent treatments for Type 1 diabetes (T1D), many children have trouble achieving glycemic control, as evidenced by elevated HbA1c levels. Maternal and child depressive symptoms, as well as child perceived stress, are associated with less optimal glycemic control. Cortisol, a stress hormone, may mediate the relationships among depressive symptoms, perceived stress, and glycemic control. The purposes of this pilot study were to (1) examine the feasibility of collecting salivary samples to measure cortisol change in prepubertal school-age children diagnosed with T1D and (2) determine effect sizes for the relationships among maternal depressive symptoms and child depressive symptoms, perceived stress, cortisol levels, and glycemic control...
December 5, 2018: Biological Research for Nursing
https://read.qxmd.com/read/30654634/allostatic-load-and-biomarkers-of-stress-in-the-preterm-infant-an-integrative-review
#11
Sharon G Casavant, Xiaomei Cong, Roslyn H Fitch, James Moore, Ted Rosenkrantz, Angela Starkweather
BACKGROUND: Every year, an estimated 15 million babies are born preterm (<37 weeks' gestational age) globally. These preterm infants are exposed to repeated stressful and often painful procedures as part of routine life-saving care within the neonatal intensive care unit (NICU). Low thresholds for tactile and nociceptive input make it more difficult for neonates to discriminate between noxious and nonnoxious stimuli, which can result in continuous activation of stress responses in an attempt to achieve stability through adaptation, or allostasis...
March 2019: Biological Research for Nursing
https://read.qxmd.com/read/30654628/are-patients-with-fibromyalgia-in-a-prothrombotic-state
#12
Francisco Molina, María Luisa Del Moral, Mercedes La Rubia, Santos Blanco, Ramón Carmona, Alma Rus
OBJECTIVES: The aim of this study was to investigate thrombosis-related parameters (blood coagulation parameters, platelet indices, red blood cell [RBC] count, and inflammatory markers) in patients with fibromyalgia (FM). METHOD: We carried out a case-control study with 35 women with FM and 12 age-matched healthy volunteers to analyze fibrinogen levels, prothrombin time, cephaline time, platelet count, platelet distribution width (PDW), mean platelet volume (MPV), RBC count, neutrophil-to-lymphocyte ratio, and platelet-to-lymphocyte ratio (PLR)...
March 2019: Biological Research for Nursing
https://read.qxmd.com/read/30415563/melatonin-improves-mood-status-and-quality-of-life-and-decreases-cortisol-levels-in-fibromyalgia
#13
M Yolanda Castaño, Maria Garrido, Ana Beatriz Rodríguez, M Ángeles Gómez
BACKGROUND: Mood disturbances are implicated in the pathogenesis of fibromyalgia. The aim of this study was to assess the effect of different doses of melatonin on quality of life, mood status, pain, anxiety, and urinary cortisol levels in patients with fibromyalgia. METHODS: After a 10-day baseline period for the collection of data about participants' initial status, participants took different doses of melatonin for 10 consecutive days each, with placebo given during the 10 days either before or between melatonin doses...
November 11, 2018: Biological Research for Nursing
https://read.qxmd.com/read/30409024/considerations-when-designing-a-microbiome-study-implications-for-nursing-science
#14
Katherine A Maki, Ana F Diallo, Mark B Lockwood, Alexis T Franks, Stefan J Green, Paule V Joseph
Nurse scientists play an important role in studying complex relationships among human genetics, environmental factors, and the microbiome, all of which can contribute to human health and disease. Therefore, it is essential that they have the tools necessary to execute a successful microbiome research study. The purpose of this article is to highlight important methodological factors for nurse scientists to consider when designing a microbiome study. In addition to considering factors that influence host-associated microbiomes (i...
November 8, 2018: Biological Research for Nursing
https://read.qxmd.com/read/30384771/nursing-research-in-the-21st-century-r-you-ready
#15
Michelle L Wright, Melinda Higgins, Jacquelyn Y Taylor, Vicki Stover Hertzberg
Nurse scientists are adept at translating findings from basic science into useful clinical- and community-based interventions to improve health. Over time, the focus of some nursing research has grown to include the assessment and evaluation of genomic and other output from high-throughput, or "omic," technologies as indicators related to health and disease. To date, the growth in the application of omics technologies in nursing research has included calls to increase attention to omics in nursing school curricula and educational training opportunities, such as the Summer Genetics Institute offered by the National Institute of Nursing Research...
November 1, 2018: Biological Research for Nursing
https://read.qxmd.com/read/30328377/beneficial-effects-of-electroacupuncture-on-neuropathic-pain-evoked-by-spinal-cord-injury-and-involvement-of-pi3k-mtor-mechanisms
#16
Yujie Wang, Yu Zhao, Xiaohui Ma, Jing Li, Junling Hou, Xiaohong Lv
The purpose of this study was to examine the beneficial effects of electroacupuncture (EA) on neuropathic pain evoked by spinal cord injury (SCI) and determine the underlying molecular mechanisms of these effects. SCI was induced in rats. Behavioral tests were performed to examine pain responses induced by mechanical and thermal stimulation. Western blot analysis was used to measure the protein expression of phosphorylated mammalian target of rapamycin (p-mTOR), mTOR-mediated phosphorylated ribosomal protein S6 kinase beta-1 (p-S6K1), and phosphorylated eukaryotic translation initiation factor 4E-binding protein 1 (p-4E-BP1) in the superficial dorsal horn of the spinal cord...
October 17, 2018: Biological Research for Nursing
https://read.qxmd.com/read/30309244/association-of-fatigue-with-tph2-genetic-polymorphisms-in-women-with-irritable-bowel-syndrome
#17
Claire J Han, Monica E Jarrett, Kevin C Cain, Sangeun Jun, Margaret M Heitkemper
Fatigue is the most common extraintestinal symptom in women with irritable bowel syndrome (IBS). Genetic polymorphisms of monoamines are associated with fatigue in many chronic diseases. In this pilot exploratory study, the primary aim was to determine whether genetic polymorphisms of tryptophan hydroxylase ( TPH1/TPH2), serotonin reuptake transporter ( SERT), or catechol-O-methyltransferase ( COMT) are associated with fatigue in women with IBS. Additionally, analysis explored whether these genetic associations with fatigue would be present when controlling for abdominal pain, psychological distress, feeling stressed, and sleepiness during the day...
October 11, 2018: Biological Research for Nursing
https://read.qxmd.com/read/30304943/role-of-exercise-activity-in-alleviating-neuropathic-pain-in-diabetes-via-inhibition-of-the-pro-inflammatory-signal-pathway
#18
Xiao-Qiu Ma, Jing Qin, Hong-Yan Li, Xiu-Li Yan, Yong Zhao, Lian-Jie Zhang
Hyperalgesia and allodynia are commonly observed in patients with diabetic neuropathy. The treatment and management of painful peripheral neuropathy is important in these patients. The purpose of this study was to examine the role of exercise in modulating neuropathic pain induced by diabetes. Diabetes was induced in rats by an intraperitoneal injection of streptozotocin (STZ). Control rats received saline injections. Groups included control rats without exercise (NT-control, n = 12), control rats with exercise (EX-control, n = 16), STZ rats without exercise (NT-STZ, n = 18), and STZ rats with exercise (EX-STZ, n = 22)...
October 10, 2018: Biological Research for Nursing
https://read.qxmd.com/read/30282476/diet-quality-and-high-sensitivity-c-reactive-protein-in-patients-with-systemic-lupus-erythematosus
#19
G Pocovi-Gerardino, M Correa-Rodríguez, J-L Callejas Rubio, R Ríos Fernández, N Ortego-Centeno, B Rueda-Medina
BACKGROUND AND AIMS: C-reactive protein (CRP) is commonly used as a biomarker for inflammation. Mild elevations of CRP have been seen in chronic autoimmune diseases like systemic lupus erythematosus (SLE), and CRP has been linked to an increased risk of cardiovascular events. Diet quality and certain dietary factors seem to influence CRP levels in healthy subjects. To date, the effect of diet on serum CRP in SLE has not been studied. Our aim was to investigate the relationship between dietary nutrients, antioxidant intake, and serum CRP in SLE...
October 3, 2018: Biological Research for Nursing
https://read.qxmd.com/read/30071743/sleep-lifestyle-behaviors-and-cardiometabolic-health-markers-in-overweight-obese-young-adults-a-pilot-study-using-the-sensewear%C3%A2-armband
#20
EunSeok Cha, Molly Sarah Talman, Ann H Massey, Fengxia Yan, Ann E Rogers
AIM: This pilot study examined associations between sleep quality and metabolic risk profiles, underlying hormones, inflammatory markers, and behaviors in overweight and obese young adults, aged 18-29 years. DESIGN: Cross-sectional, descriptive, correlational study design. METHOD: A partial sample ( n = 29) was re-recruited from a parent study on screening for risk of early-onset diabetes. BodyMedia's SenseWear® armband was used to assess sleep quality...
October 2018: Biological Research for Nursing
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