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Journals Prostate Cancer and Prostatic ...

Prostate Cancer and Prostatic Diseases

https://read.qxmd.com/read/38030887/the-relative-impact-of-lymph-node-metastasis-and-seminal-vesical-invasion-on-oncologic-outcomes-following-radical-prostatectomy
#1
EDITORIAL
Claudia Kesch, Giorgio Calleris, Guillaume Ploussard
No abstract text is available yet for this article.
November 29, 2023: Prostate Cancer and Prostatic Diseases
https://read.qxmd.com/read/38017295/comparison-of-18-f-based-psma-radiotracers-with-68-ga-ga-psma-11-in-pet-ct-imaging-of-prostate-cancer-a-systematic-review-and-meta-analysis
#2
REVIEW
Siyu Huang, Sean Ong, Dean McKenzie, Adam Mirabelli, David C Chen, Thilakavathi Chengodu, Declan G Murphy, Michael S Hofman, Nathan Lawrentschuk, Marlon Perera
BACKGROUND: Prostate-specific membrane antigen (PSMA) positron emission tomography (PET)/computed tomography (CT) has become an increasingly established imaging modality in the staging of prostate cancer (PCa). Numerous PSMA-based tracers are currently available, however, there is a lack of consensus on the optimal radiotracer(s) for PSMA PET/CT. This study aims to investigate whether Fluorine-18 (18 F)-labelled PSMA PET/CT is significantly different from Gallium-68 (68 Ga) in primary diagnosis and/or secondary staging of prostate cancer following biochemical recurrence...
November 28, 2023: Prostate Cancer and Prostatic Diseases
https://read.qxmd.com/read/38007533/high-glut1-membrane-expression-and-low-psma-membrane-expression-in-ductal-adenocarcinoma-and-intraductal-carcinoma-of-the-prostate
#3
JOURNAL ARTICLE
Xingming Wang, Li Zhou, Lin Qi, Ye Zhang, Hongling Yin, Yu Gan, Xiaomei Gao, Yi Cai
BACKGROUND: Both Ductal Adenocarcinoma (DAC) and Intraductal Carcinoma (IDC) of the prostate are generally associated with aggressive clinical behavior and poor prognosis, which were linked with discordant FDG positivity and low Prostate-Specific Membrane Antigen (PSMA) expression. A recent study only cited a DAC patient with low 68 Ga-PSMA-11 PET/CT uptake but high 18 F-FDG PET/CT uptake, however, there is lack of directly compared articles nor large data sets. Hence, the objective of this study was to investigate the expression of PSMA and GLUT1 in DAC and IDC-P patients...
November 25, 2023: Prostate Cancer and Prostatic Diseases
https://read.qxmd.com/read/38001362/comparison-of-procedural-anxiety-and-pain-associated-with-conventional-transrectal-ultrasound-prostate-biopsy-to-magnetic-resonance-imaging-ultrasound-fusion-guided-biopsy-a-prospective-cohort-trial
#4
JOURNAL ARTICLE
Sriram Deivasigamani, Eric S Adams, Srinath Kotamarti, Mahdi Mottaghi, Terek Taha, Ali Aminsharifi, Zoe Michael, Denis Seguier, Thomas J Polascik
BACKGROUND: Prostate cancer (PCa) diagnosis relies on biopsies, with transrectal ultrasound (TRUS) biopsies being common. Fusion biopsy (FB) offers improved diagnostic accuracy, but the pain and anxiety experienced by patients during biopsies is often overlooked. This study aims to compare pain and anxiety levels between standard TRUS-guided biopsy (STB) and systematic plus MRI/US fusion biopsy (STB + FB). MATERIALS AND METHODS: The study involved adult men undergoing biopsies, receiving identical peri-procedural care, including 2% lidocaine jelly in the rectum and subsequent 1% lidocaine injections (10cc per side) into the prostate-seminal vesicle junction and prostatic apical areas bilaterally...
November 25, 2023: Prostate Cancer and Prostatic Diseases
https://read.qxmd.com/read/37985863/is-there-a-role-for-radical-prostatectomy-in-the-management-of-oligometastatic-prostate-cancer-a-systematic-review
#5
REVIEW
A Saouli, A Touzani, A Martini, J B Beauval, H Dergamoun, I Ziouziou, N Deffar, G Ploussard, A Ouzzane
CONTEXT: There is a growing interest about the role of radical prostatectomy (RP) in local cancer control in oligometastatic prostate cancer (PCa). PURPOSE: To evaluate the oncological and functional outcomes of RP in the management of oligometastatic PCa through a systematic review. METHODS: A systematic review search was performed and the following bibliographic databases were accessed: PubMed, Scopus, Embase and the Cochrane central register of controlled trials were searched from January 2000 to November 2022...
November 20, 2023: Prostate Cancer and Prostatic Diseases
https://read.qxmd.com/read/37963984/correction-hormonal-treatment-for-newly-diagnosed-metastatic-prostate-cancer-a-population-based-study-from-the-california-cancer-registry
#6
David J Benjamin, Anshu Shrestha, Dimitra Fellman, Rosemary D Cress, Mark P Lythgoe, Arash Rezazadeh Kalebasty
No abstract text is available yet for this article.
November 14, 2023: Prostate Cancer and Prostatic Diseases
https://read.qxmd.com/read/37950022/chatgpt-in-prostate-cancer-myth-or-reality
#7
EDITORIAL
Riccardo Lombardo, Antonio Cicione, Giuseppe Santoro, Cosimo De Nunzio
No abstract text is available yet for this article.
November 10, 2023: Prostate Cancer and Prostatic Diseases
https://read.qxmd.com/read/37935879/early-psa-decline-after-starting-second-generation-hormone-therapy-in-the-post-docetaxel-setting-predicts-cancer-specific-survival-in-metastatic-castrate-resistant-prostate-cancer
#8
JOURNAL ARTICLE
Mohamed E Ahmed, Matthew S Lee, Ahmed M Mahmoud, Vidhu B Joshi, Ajay Gopalakrishna, Raevti Bole, Rimki Haloi, A Tuba Kendi, Michael S Bold, Alan H Bryce, Robert Jeffrey Karnes, Eugene D Kwon, Daniel S Childs, Jack R Andrews
BACKGROUND: The objective of this study was to evaluate the prognostic value of early PSA decline following initiation of second-generation hormone therapy (2nd HT), namely abiraterone acetate or enzalutamide, in patients with taxane-refractory metastatic castrate-resistant prostate cancer (mCRPC) and evaluate utility of this metric in informing intensified surveillance/imaging protocols. METHODS: We retrospectively identified 75 mCRPC patients treated with 2nd HT following docetaxel failure (defined as PSA rise and radiographic progression)...
November 7, 2023: Prostate Cancer and Prostatic Diseases
https://read.qxmd.com/read/37932522/external-validation-of-nomograms-including-mri-features-for-the-prediction-of-side-specific-extraprostatic-extension
#9
JOURNAL ARTICLE
J G Heetman, E J R J van der Hoeven, P Rajwa, F Zattoni, C Kesch, S Shariat, F Dal Moro, G Novara, G La Bombara, F Sattin, N von Ostau, N Pötsch, P A T Baltzer, L Wever, J P A Van Basten, H H E Van Melick, R C N Van den Bergh, G Gandaglia, T F W Soeterik
BACKGROUND: Prediction of side-specific extraprostatic extension (EPE) is crucial in selecting patients for nerve-sparing radical prostatectomy (RP). Multiple nomograms, which include magnetic resonance imaging (MRI) information, are available predict side-specific EPE. It is crucial that the accuracy of these nomograms is assessed with external validation to ensure they can be used in clinical practice to support medical decision-making. METHODS: Data of prostate cancer (PCa) patients that underwent robot-assisted RP (RARP) from 2017 to 2021 at four European tertiary referral centers were collected retrospectively...
November 6, 2023: Prostate Cancer and Prostatic Diseases
https://read.qxmd.com/read/37932521/editorial-new-horizons-in-robotic-platforms
#10
EDITORIAL
Riccardo Lombardo, Matteo Romagnoli, Cosimo De Nunzio, Simone Albisinni
No abstract text is available yet for this article.
November 6, 2023: Prostate Cancer and Prostatic Diseases
https://read.qxmd.com/read/37925488/digital-informed-consent-for-urological-surgery-randomized-controlled-study-comparing-multimedia-supported-vs-traditional-paper-based-informed-consent-concerning-satisfaction-anxiety-information-gain-and-time-efficiency
#11
JOURNAL ARTICLE
Maximilian Haack, Nikita D Fischer, Lisa Frey, Peter Sparwasser, Robert Dotzauer, Gregor Duwe, Axel Haferkamp, Hendrik Borgmann
INTRODUCTION: Due to a lack of time and staff, informed consent (IC) in clinical practice often lacks clarity, comprehensibility and scope of information. Digital media offer great potential to enhance IC. Aim of this study is to evaluate the effectiveness of multimedia-supported compared to traditional paper-based IC. METHODS: In the randomized, controlled, three-arm DICon (Digital Informed Consent for urological surgery) study 70 patients with an indication for prostate biopsy were randomized 1:1:1 to receive traditional paper-based IC vs...
November 4, 2023: Prostate Cancer and Prostatic Diseases
https://read.qxmd.com/read/37923807/quality-of-information-and-appropriateness-of-chatgpt-outputs-for-urology-patients
#12
LETTER
Andrea Cocci, Marta Pezzoli, Mattia Lo Re, Giorgio Ivan Russo, Maria Giovanna Asmundo, Mikkel Fode, Giovanni Cacciamani, Sebastiano Cimino, Andrea Minervini, Emil Durukan
No abstract text is available yet for this article.
November 3, 2023: Prostate Cancer and Prostatic Diseases
https://read.qxmd.com/read/37884615/retreatment-rates-and-postprocedural-complications-are-higher-than-expected-after-bph-surgeries-a-us-healthcare-claims-and-utilization-study
#13
JOURNAL ARTICLE
Steve Kaplan, Ronald P Kaufman, Thomas Mueller, Dean Elterman, Bilal Chughtai, Daniel Rukstalis, Henry Woo, Claus Roehrborn
BACKGROUND: Up to 50% of men over 50 and 80% over 80 are affected by BPH. Shared decision-making regarding BPH treatment options can benefit from an improved understanding of relative risks and benefits for various treatments. METHODS: Data for this longitudinal retrospective population-based cohort study were obtained from a random sample of US Medicare and commercial claims (IBM Watson MarketScan) and restricted to men undergoing BPH surgery (TURP, PVP, PUL, WVTT) from 2015 to 2021 across all sites of service...
October 26, 2023: Prostate Cancer and Prostatic Diseases
https://read.qxmd.com/read/37884614/shifting-the-paradigm-in-high-risk-prostate-cancer-how-good-is-tnm-alone
#14
EDITORIAL
Fouad Aoun, Elie Helou, Simone Albisinni
No abstract text is available yet for this article.
October 26, 2023: Prostate Cancer and Prostatic Diseases
https://read.qxmd.com/read/37884613/safety-and-tolerability-of-long-term-treatment-with-darolutamide-in-patients-with-metastatic-castration-resistant-prostate-cancer
#15
JOURNAL ARTICLE
Robert Hugh Jones, Karim Fizazi, Nicholas D James, Teuvo L Tammela, Nobuaki Matsubara, Frank Priou, Philippe Beuzeboc, Thierry Lesimple, Petri Bono, Vesa Kataja, Jorge A Garcia, Andrew Protheroe, Neal Shore, John Aspegren, Heikki Joensuu, Iris Kuss, Sabine Fiala-Buskies, Egils Vjaters
BACKGROUND: In patients with metastatic castration-resistant prostate cancer, darolutamide was well tolerated for 25 months, but minimal long-term safety data are available. METHODS: Treatment-emergent adverse events (TEAEs) for patients receiving darolutamide for a median of 38 months (n = 13) are described in this pooled analysis of individual patient data from phase 1/2 studies. RESULTS: All patients reported TEAEs (mostly grade 1/2)...
October 26, 2023: Prostate Cancer and Prostatic Diseases
https://read.qxmd.com/read/37875644/impact-of-peritoneal-reconfiguration-on-lymphocele-formation-after-robot-assisted-radical-prostatectomy-with-pelvic-lymph-node-dissection-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#16
REVIEW
Francesco Ditonno, Celeste Manfredi, Antonio Franco, Alessandro Veccia, Fabrizio Dal Moro, Cosimo De Nunzio, Marco De Sio, Alessandro Antonelli, Riccardo Autorino
BACKGROUND: Different strategies have been proposed to prevent lymphocele (LC) formation after radical prostatectomy (RARP) with pelvic lymph node dissection (PLND). According to several recently published randomized control trials (RCTs) on the topic, peritoneal reconfiguration appears to be associated with promising results. This systematic review aimed to assess the impact of peritoneal reconfiguration on LC formation in patients undergoing RARP and PLND. METHODS: A comprehensive bibliographic search was conducted in August 2023...
October 24, 2023: Prostate Cancer and Prostatic Diseases
https://read.qxmd.com/read/37872252/when-you-say-prostate-don-t-forget-to-say-bladder
#17
EDITORIAL
Luca Cindolo, Emanuele Rubilotta, Wayne Kuang, Alessandro Antonelli
No abstract text is available yet for this article.
October 23, 2023: Prostate Cancer and Prostatic Diseases
https://read.qxmd.com/read/37872251/effect-of-omega-3-fatty-acid-diet-on-prostate-cancer-progression-and-cholesterol-efflux-in-tumor-associated-macrophages-dependence-on-gpr120
#18
JOURNAL ARTICLE
Pei Liang, Susanne M Henning, Tristan Grogan, David Elashoff, Jonathan Said, Pinchas Cohen, William J Aronson
BACKGROUND: Preclinical and clinical translational research supports the role of an ω-3 fatty acid diet for prostate cancer prevention and treatment. The anti-prostate cancer effects of an ω-3 diet require a functional host g-protein coupled receptor 120 (GPR120) but the underlying effects on the tumor microenvironment and host immune system are yet to be elucidated. METHODS: Friend leukemia virus B (FVB) mice received bone marrow from green fluorescent protein (GFP) labeled GPR120 wild-type (WT) or knockout (KO) mice followed by implanting Myc-driven mouse prostate cancer (MycCap) allografts and feeding an ω-3 or ω-6 diet...
October 23, 2023: Prostate Cancer and Prostatic Diseases
https://read.qxmd.com/read/37872250/characteristics-of-incidental-prostate-cancer-in-the-united-states
#19
JOURNAL ARTICLE
Lukas Scheipner, Reha-Baris Incesu, Simone Morra, Andrea Baudo, Anis Assad, Letizia Maria Ippolita Jannello, Carolin Siech, Mario de Angelis, Francesco Barletta, Zhe Tian, Fred Saad, Shahrokh F Shariat, Alberto Briganti, Felix K H Chun, Derya Tilki, Nicola Longo, Luca Carmignani, Ottavio De Cobelli, Sascha Ahyai, Pierre I Karakiewicz
BACKGROUND: Data regarding North-American incidental (cT1a/b) prostate cancer (PCa) patients is scarce. To address this, incidental PCa characteristics (age, PSA values at diagnosis, Gleason score [GS]), subsequent treatment and cancer-specific survival (CSS) rates were explored. METHODS: Incidental PCa patients were identified within the Surveillance, Epidemiology, and End Results (SEER) database (2004-2015). Descriptive statistics, annual percentage changes (EAPC), Kaplan-Meier estimates, as well as Cox regression models were used...
October 23, 2023: Prostate Cancer and Prostatic Diseases
https://read.qxmd.com/read/37864027/comparison-of-procedural-anxiety-and-pain-associated-with-conventional-transrectal-ultrasound-prostate-biopsy-to-magnetic-resonance-imaging-ultrasound-fusion-guided-biopsy-a-prospective-cohort-trial
#20
EDITORIAL
Celeste Manfredi, Francesco Ditonno
No abstract text is available yet for this article.
October 20, 2023: Prostate Cancer and Prostatic Diseases
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