Journals Journal of Cardiovascular Magn...

Journal of Cardiovascular Magnetic Resonance
Moses P Cook, Wahiba Dhahri, Michael A Laflamme, Nilesh R Ghugre, Graham A Wright
BACKGROUND: Novel treatment strategies are needed to improve the structure and function in the myocardium post infarction. In vitro-matured pluripotent stem cell-derived cardiomyocytes (PSC-CMs), have been shown to be a promising regenerative strategy. We hypothesized that mature PSC-CMs will have anisotropic structure and improved cell alignment when compared to immature PSC-CMs using magnetic resonance imaging (MRI) in a guinea pig model of cardiac injury. METHODS: Guinea pigs (n=16) were cryoinjured on day -10, followed by transplantation of either 108 polydimethylsiloxane-matured PSC-CMs (PDMS, n=6) or 108 immature tissue culture plastic-generated PSC-CMs (TCP, n=6) on day 0...
May 23, 2024: Journal of Cardiovascular Magnetic Resonance
Zahra Raisi-Estabragh
No abstract text is available yet for this article.
May 8, 2024: Journal of Cardiovascular Magnetic Resonance
Imon Banerjee, Amara Tariq, Chieh-Ju Chao
No abstract text is available yet for this article.
April 6, 2024: Journal of Cardiovascular Magnetic Resonance
Federica Viola, Mariana Bustamante, Ann Bolger, Jan Engvall, Tino Ebbers
BACKGROUND: Diastolic left ventricular (LV) dysfunction is a powerful contributor to the symptoms and prognosis of patients with heart failure. In patients with depressed LV systolic function, the E/A ratio, the ratio between the peak early (E) and the peak late (A) transmitral flow velocity, is the first step to defining the grade of diastolic dysfunction. Doppler echocardiography (echo) is the preferred imaging technique for diastolic function assessment, while cardiovascular magnetic resonance (CMR) is less established as a method...
March 30, 2024: Journal of Cardiovascular Magnetic Resonance
Michael P DiLorenzo, Simon Lee, Rahul H Rathod, Francesca Raimondi, Kanwal M Farooqi, Supriya S Jain, Margaret M Samyn, Tiffanie R Johnson, Laura J Olivieri, Mark A Fogel, Wyman W Lai, Pierangelo Renella, Andrew J Powell, Sujatha Buddhe, Caitlin Stafford, Jason N Johnson, Willem A Helbing, Kuberan Pushparajah, Inga Voges, Vivek Muthurangu, Kimberley G Miles, Gerald Greil, Colin J McMahon, Timothy C Slesnick, Brian M Fonseca, Shaine A Morris, Jonathan H Soslow, Lars Grosse-Wortmann, Rebecca S Beroukhim, Heynric B Grotenhuis
Cardiovascular magnetic resonance (CMR) has become the reference standard for quantitative and qualitative assessment of ventricular function, blood flow, and myocardial tissue characterization. There is a preponderance of large CMR studies and registries in adults; However, similarly powered studies are lacking for the pediatric and congenital heart disease (PCHD) population. To date, most CMR studies in children are limited to small single or multicenter studies, thereby limiting the conclusions that can be drawn...
March 23, 2024: Journal of Cardiovascular Magnetic Resonance
Sameer Zaman, Kavitha Vimalesvaran, Digby Chappell, Marta Varela, Nicholas S Peters, Hunain Shiwani, Kristopher D Knott, Rhodri H Davies, James C Moon, Anil A Bharath, Nick Wf Linton, Darrel P Francis, Graham D Cole, James P Howard
BACKGROUND: Late gadolinium enhancement (LGE) of the myocardium has significant diagnostic and prognostic implications, with even small areas of enhancement being important. Distinguishing between definitely normal and definitely abnormal LGE images is usually straightforward; but diagnostic uncertainty arises when reporters are not sure whether the observed LGE is genuine or not. This uncertainty might be resolved by repetition (to remove artefact) or further acquisition of intersecting images, but this must take place before the scan finishes...
March 22, 2024: Journal of Cardiovascular Magnetic Resonance
Andrew Phair, Anastasia Fotaki, Lina Felsner, Thomas J Fletcher, Haikun Qi, René M Botnar, Claudia Prieto
BACKGROUND: Cardiovascular magnetic resonance (CMR) is an important imaging modality for the assessment and management of adult patients with congenital heart disease (CHD). However, conventional techniques for three-dimensional (3D) whole-heart acquisition involve long and unpredictable scan times and methods that accelerate scans via k-space undersampling often rely on long iterative reconstructions. Deep-learning-based reconstruction methods have recently attracted much interest due to their capacity to provide fast reconstructions while often outperforming existing state-of-the-art methods...
March 22, 2024: Journal of Cardiovascular Magnetic Resonance
Andrik Ballenberger, Amke Caliebe, Sylvia Krupickova, Anselm Uebing, Dominik Daniel Gabbert, Inga Voges
BACKGROUND: Cardiovascular magnetic resonance (CMR) has established itself as the gold standard for serial assessment of systemic right ventricular (RV) performance but due to the lack of standardized RV reference values for HLHS patients, the interpretation of RV volumetric data in HLHS remains difficult. Therefore, this study aimed to close this gap by providing CMR reference values for the systemic RV in HLHS patients. METHODS: CMR scans of 160 children, adolescents and young adults (age range 2...
March 16, 2024: Journal of Cardiovascular Magnetic Resonance
Christopher W Roy, Bastien Milani, Jérôme Yerly, Salim Si-Mohamed, Ludovica Romanin, Aurélien Bustin, Estelle Tenisch, Tobias Rutz, Milan Prsa, Matthias Stuber
BACKGROUND: Free-running cardiac and respiratory motion-resolved whole-heart 5D MRI can reduce scan planning and provide a means of evaluating respiratory-driven changes in clinical parameters of interest. However, respiratory-resolved imaging can be limited by user-defined parameters which create trade-offs between residual artifact and motion blur. In this work, we develop and validate strategies for both correction of intra-bin and compensation of inter-bin respiratory motion to improve the quality of 5D MRI...
March 16, 2024: Journal of Cardiovascular Magnetic Resonance
Norain Talib, Matteo Fronza, Constantin Arndt Marschner, Paaladinesh Thavendiranathan, Gauri Rani Karur, Kate Hanneman
BACKGROUND: The purpose of this study was to evaluate cardiovascular magnetic resonance (CMR) findings and their relationship to longer-term clinical outcomes in patients with suspected myocarditis following COVID-19 vaccination. METHODS: Consecutive adult patients who underwent clinically indicated CMR for evaluation of suspected myocarditis following mRNA-based COVID-19 vaccination at a single center between 2021-2022 were retrospectively evaluated. Patients were classified based on the revised Lake Louise criteria for T1-based abnormalities (late gadolinium enhancement or high T1 values) and T2-based abnormalities (regional T2-hyperintensity or high T2 values)...
March 11, 2024: Journal of Cardiovascular Magnetic Resonance
Babak Salam, Dmitrij Kravchenko, Sebastian Nowak, Alois M Sprinkart, Leonie Weinhold, Anna Odenthal, Narine Mesropyan, Leon M Bischoff, Ulrike Attenberger, Daniel L Kuetting, Julian A Luetkens, Alexander Isaak
BACKGROUND: Patients are increasingly using Generative Pre-trained Transformer 4 (GPT-4) to better understand their own radiology findings. PURPOSE: To evaluate the performance of GPT-4 in transforming cardiovascular magnetic resonance (CMR) reports into text comprehensible for medical laypersons. MATERIALS AND METHODS: ChatGPT with GPT-4 architecture was used to generate three different explained versions of 20 various CMR reports using the same prompt "Explain the radiology report in a language understandable to a medical layperson" (n=60)...
March 7, 2024: Journal of Cardiovascular Magnetic Resonance
Kei Nakata, Selcuk Kucukseymen, Xiaoying Cai, Tuyen Yankama, Jennifer Rodriguez, Eiryu Sai, Patrick Pierce, Long Ngo, Shiro Nakamori, Nadine Tung, Warren J Manning, Reza Nezafat
BACKGROUND: Left ventricular ejection fraction (LVEF) is the most commonly clinically used imaging parameter for assessing cancer therapy-related cardiac dysfunction (CTRCD). However, LVEF declines may occur late, after substantial injury. This study sought to investigate cardiovascular magnetic resonance (CMR) imaging markers of subclinical cardiac injury in a miniature swine model. METHODS: Female Yucatan miniature swine (n=14) received doxorubicin (2mg/kg) every 3 weeks for 4 cycles...
March 7, 2024: Journal of Cardiovascular Magnetic Resonance
Sören J Backhaus, Alexander Schulz, Torben Lange, Ruben Evertz, Johannes T Kowallick, Gerd Hasenfuß, Andreas Schuster
BACKGROUND: Identification of increased pulmonary capillary wedge pressure (PCWP) by right heart catheterisation (RHC) is the reference standard for the diagnosis of heart failure with preserved ejection fraction (HFpEF). Recently, cardiovascular magnetic resonance (CMR) imaging estimation of PCWP at rest was introduced as a non-invasive alternative. Since many patients are only identified during physiological exercise-stress we hypothesised that novel exercise-stress CMR derived PCWP emerges superior compared to its assessment at rest...
February 29, 2024: Journal of Cardiovascular Magnetic Resonance
Tobias Hoh, Isabel Margolis, Jonathan Weine, Thomas Joyce, Robert Manka, Miriam Weisskopf, Nikola Cesarovic, Maximilian Fuetterer, Sebastian Kozerke
BACKGROUND: Automatic myocardial scar segmentation from late gadolinium enhancement (LGE) images using neural networks promises an alternative to time-consuming and observer-dependent semi-automatic approaches. However, alterations in data acquisition, reconstruction as well as post-processing may compromise network performance. The objective of the present work was to systematically assess network performance degradation due to a mismatch of point-spread function between training and testing data...
February 29, 2024: Journal of Cardiovascular Magnetic Resonance
Kevin Bouaou, Thomas Dietenbeck, Gilles Soulat, Ioannis Bargiotas, Sophia Houriez-Gombaud-Saintonge, Alain De Cesare, Umit Gencer, Alain Giron, Elena Jiménez, Emmanuel Messas, Didier Lucor, Emilie Bollache, Elie Mousseaux, Nadjia Kachenoura
BACKGROUND: Ascending thoracic aortic aneurysm (ATAA) is a silent and threatening dilation of the ascending aorta (AscAo). Maximal aortic diameter which is currently used for ATAA patients management and surgery planning has been shown to inadequately characterize risk of dissection in a large proportion of patients. Our aim was to propose a comprehensive quantitative evaluation of aortic morphology and pressure-flow-wall associations from 4D flow MRI data in healthy aging and in patients with ATAA...
February 23, 2024: Journal of Cardiovascular Magnetic Resonance
David Liddle, Addison Gearhart, Lynn A Sleeper, Minmin Lu, Eric Feins, David N Schidlow, Sunil Ghelani, Andrew J Powell, Sitaram Emani, Rebecca S Beroukhim
BACKGROUND: Identification of risk factors for biventricular (BiV) repair in children with hypoplastic left ventricles (HLV) has been challenging. We sought to identify preoperative cardiovascular magnetic resonance (CMR) predictors of outcome in patients with HLVs who underwent BiV repair, with a focus on the mitral valve (MV). METHODS: Single center retrospective analysis of preoperative CMRs on patients with HLV (≤50ml/m2 ) and no endocardial fibroelastosis who underwent BiV repair from 2005-2022...
February 23, 2024: Journal of Cardiovascular Magnetic Resonance
Aravindan Kolandaivelu, Christopher G Bruce, Felicia Seeman, Dursun Korel Yildirim, Adrienne E Campbell-Washburn, Robert J Lederman, Daniel A Herzka
BACKGROUND: The 12-lead electrocardiogram (ECG) is a standard diagnostic tool for monitoring cardiac ischemia and heart rhythm during cardiac interventional procedures and stress testing. These procedures can benefit from magnetic resonance imaging (MRI) information; however, the MRI scanner magnetic field leads to ECG distortion that limits ECG interpretation. This study evaluated the potential for improved ECG interpretation in a "low field" 0.55T MRI scanner. METHODS: 12-lead ECGs were recorded inside 0...
February 9, 2024: Journal of Cardiovascular Magnetic Resonance
Ersin Cavus, Jan N Schneider, Eleonora di Carluccio, Andreas Ziegler, Alena Haack, Francisco Ojeda, Celeste Chevalier, Charlotte Jahnke, Katharina A Riedl, Ulf K Radunski, Raphael Twerenbold, Paulus Kirchhof, Stefan Blankenberg, Gerhard Adam, Enver Tahir, Gunnar K Lund, Kai Muellerleile
BACKGROUND: The presence of myocardial scar is associated with poor prognosis in several underlying diseases. Late-gadolinium-enhancement (LGE) cardiovascular magnetic resonance (CMR) imaging reveals clinically silent "unrecognized myocardial scar" (UMS), but the etiology of UMS often remains unclear. This population-based CMR study evaluated prevalence, localization, patterns and risk factors of UMS. METHODS: The study population consisted of 1064 consecutive Hamburg City Health study participants without a history of coronary heart disease or myocarditis...
February 8, 2024: Journal of Cardiovascular Magnetic Resonance
Henrik Engblom, Ellen Ostenfeld, Marcus Carlsson, Julius Åkesson, Anthony H Aletras, Hui Xue, Peter Kellman, Håkan Arheden
BACKGROUND: Quantitative CMR first pass perfusion maps are conventionally acquired with 3 short-axis views (basal, mid and apical) in every heartbeat (3SAX/1RR). Thus, a significant part of the LV myocardium, including the apex, is not covered. The aims of this study were 1) to investigate if perfusion maps acquired with 3 short-axis views sampled every other RR-interval (2RR) yield comparable quantitative measures of myocardial perfusion (MP) as 1RR and 2) to assess if acquiring 3 additional perfusion views (i...
February 3, 2024: Journal of Cardiovascular Magnetic Resonance
Mariana B L Falcão, Adèle L C Mackowiak, Giulia M C Rossi, Milan Prša, Estelle Tenisch, Simone Rumac, Mario Bacher, Tobias Rutz, Ruud B van Heeswijk, Peter Speier, Michael Markl, Jessica A M Bastiaansen, Matthias Stuber, Christopher W Roy
BACKGROUND: 4D flow MRI often relies on the injection of gadolinium- or iron-oxide-based contrast agents to improve vessel delineation. In this work, a novel technique is developed to acquire and reconstruct 4D flow data with excellent dynamic visualization of blood vessels but without the need for contrast injection. Synchronization of Neighboring Acquisitions by Physiological Signals (SyNAPS) uses Pilot Tone (PT) navigation to retrospectively synchronize the reconstruction of two free-running 3D radial acquisitions, to create co-registered anatomy and flow images...
February 1, 2024: Journal of Cardiovascular Magnetic Resonance
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