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Journal of Cardiovascular Magnetic Resonance

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https://read.qxmd.com/read/30728035/in-vitro-optimization-and-comparison-of-ct-angiography-versus-radial-cardiovascular-magnetic-resonance-for-the-quantification-of-cross-sectional-areas-and-coronary-endothelial-function
#1
Jérôme Yerly, Fabio Becce, Ruud B van Heeswijk, Francis R Verdun, Danilo Gubian, Reto Meuli, Matthias Stuber
BACKGROUND: Our objectives were first to determine the optimal coronary computed tomography angiography (CTA) protocol for the quantification and detection of simulated coronary artery cross-sectional area (CSA) differences in vitro, and secondly to quantitatively compare the performance of the optimized CTA protocol with a previously validated radial coronary cardiovascular magnetic resonance (CMR) technique. METHODS: 256-multidetector CTA and radial coronary CMR were used to obtain images of a custom in vitro resolution phantom simulating a range of physiological responses of coronary arteries to stress...
February 7, 2019: Journal of Cardiovascular Magnetic Resonance
https://read.qxmd.com/read/30700314/myocardial-triglycerides-in-cardiac-amyloidosis-assessed-by-proton-cardiovascular-magnetic-resonance-spectroscopy
#2
Mareike Gastl, Sophie M Peereboom, Alexander Gotschy, Maximilian Fuetterer, Constantin von Deuster, Florian Boenner, Malte Kelm, Rahel Schwotzer, Andreas J Flammer, Robert Manka, Sebastian Kozerke
BACKGROUND: Cardiac involvement of amyloidosis leads to left-ventricular (LV) wall thickening with progressive heart failure requiring rehospitalization. Cardiovascular magnetic resonance (CMR) is a valuable tool to non-invasively assess myocardial thickening as well as structural changes. Proton CMR spectroscopy (1 H-CMRS) additionally allows assessing metabolites including triglycerides (TG) and total creatine (CR). However, opposing results exist regarding utilization of these metabolites in LV hypertrophy or thickening...
January 31, 2019: Journal of Cardiovascular Magnetic Resonance
https://read.qxmd.com/read/30674318/safety-and-prognostic-value-of-regadenoson-stress-cardiovascular-magnetic-resonance-imaging-in-heart-transplant-recipients
#3
Felipe Kazmirczak, Prabhjot S Nijjar, Lei Zhang, Andrew Hughes, Ko-Hsuan Amy Chen, Osama Okasha, Cindy M Martin, Mehmet Akçakaya, Afshin Farzaneh-Far, Chetan Shenoy
BACKGROUND: There is a critical need for non-invasive methods to detect coronary allograft vasculopathy and to risk stratify heart transplant recipients. Vasodilator stress testing using cardiovascular magnetic resonance imaging (CMR) is a promising technique for this purpose. We aimed to evaluate the safety and the prognostic value of regadenoson stress CMR in heart transplant recipients. METHODS: To evaluate the safety, we assessed adverse effects in a retrospective matched cohort study of consecutive heart transplant recipients who underwent regadenoson stress CMR matched in a 2:1 ratio to age- and gender-matched non-heart transplant patients...
January 24, 2019: Journal of Cardiovascular Magnetic Resonance
https://read.qxmd.com/read/30661506/fetal-hemodynamics-and-cardiac-streaming-assessed-by-4d-flow-cardiovascular-magnetic-resonance-in-fetal-sheep
#4
Eric M Schrauben, Brahmdeep Singh Saini, Jack R T Darby, Jia Yin Soo, Mitchell C Lock, Elaine Stirrat, Greg Stortz, John G Sled, Janna L Morrison, Mike Seed, Christopher K Macgowan
BACKGROUND: To date it has not been possible to obtain a comprehensive 3D assessment of fetal hemodynamics because of the technical challenges inherent in imaging small cardiac structures, movement of the fetus during data acquisition, and the difficulty of fusing data from multiple cardiac cycles when a cardiac gating signal is absent. Here we propose the combination of volumetric velocity-sensitive cardiovascular magnetic resonance imaging ("4D flow" CMR) and a specialized animal preparation (catheters to monitor fetal heart rate, anesthesia to immobilize mother and fetus) to examine fetal sheep cardiac hemodynamics in utero...
January 21, 2019: Journal of Cardiovascular Magnetic Resonance
https://read.qxmd.com/read/30651110/late-effects-of-pediatric-hematopoietic-stem-cell-transplantation-on-left-ventricular-function-aortic-stiffness-and-myocardial-tissue-characteristics
#5
Elisabeth H M Paiman, Marloes Louwerens, Dorine Bresters, Jos J M Westenberg, Qian Tao, Rob J van der Geest, Arjan C Lankester, Arno A W Roest, Hildo J Lamb
BACKGROUND: Pediatric hematopoietic stem cell transplantation (HSCT) recipients are at increased risk of cardiovascular disease later in life. As HSCT survival has significantly improved, with a growing number of HSCT indications, tailored screening strategies for HSCT-related late effects are warranted. Little is known regarding the value of cardiovascular magnetic resonance (CMR) for early identification of high-risk patients after HSCT, before symptomatic cardiovascular disease manifests...
January 17, 2019: Journal of Cardiovascular Magnetic Resonance
https://read.qxmd.com/read/30636630/automated-analysis-of-cardiovascular-magnetic-resonance-myocardial-native-t-1-mapping-images-using-fully-convolutional-neural-networks
#6
Ahmed S Fahmy, Hossam El-Rewaidy, Maryam Nezafat, Shiro Nakamori, Reza Nezafat
BACKGROUND: Cardiovascular magnetic resonance (CMR) myocardial native T1 mapping allows assessment of interstitial diffuse fibrosis. In this technique, the global and regional T1 are measured manually by drawing region of interest in motion-corrected T1 maps. The manual analysis contributes to an already lengthy CMR analysis workflow and impacts measurements reproducibility. In this study, we propose an automated method for combined myocardium segmentation, alignment, and T1 calculation for myocardial T1 mapping...
January 14, 2019: Journal of Cardiovascular Magnetic Resonance
https://read.qxmd.com/read/30626437/accelerated-free-breathing-3d-t1%C3%AF-cardiovascular-magnetic-resonance-using-multicoil-compressed-sensing
#7
Srikant Kamesh Iyer, Brianna Moon, Eileen Hwuang, Yuchi Han, Michael Solomon, Harold Litt, Walter R Witschey
BACKGROUND: Endogenous contrast T1ρ cardiovascular magnetic resonance (CMR) can detect scar or infiltrative fibrosis in patients with ischemic or non-ischemic cardiomyopathy. Existing 2D T1ρ techniques have limited spatial coverage or require multiple breath-holds. The purpose of this project was to develop an accelerated, free-breathing 3D T1ρ mapping sequence with whole left ventricle coverage using a multicoil, compressed sensing (CS) reconstruction technique for rapid reconstruction of undersampled k-space data...
January 10, 2019: Journal of Cardiovascular Magnetic Resonance
https://read.qxmd.com/read/30612579/association-of-left-atrial-volume-index-and-all-cause-mortality-in-patients-referred-for-routine-cardiovascular-magnetic-resonance-a-multicenter-study
#8
Mohammad A Khan, Eric Y Yang, Yang Zhan, Robert M Judd, Wenyaw Chan, Faisal Nabi, John F Heitner, Raymond J Kim, Igor Klem, Sherif F Nagueh, Dipan J Shah
BACKGROUND: Routine cine cardiovascular magnetic resonance (CMR) allows for the measurement of left atrial (LA) volumes. Normal reference values for LA volumes have been published based on a group of European individuals without known cardiovascular disease (CVD) but not on one of similar United States (US) based volunteers. Furthermore, the association between grades of LA dilatation by CMR and outcomes has not been established. We aimed to assess the relationship between grades of LA dilatation measured on CMR based on US volunteers without known CVD and all-cause mortality in a large, multicenter cohort of patients referred for a clinically indicated CMR scan...
January 7, 2019: Journal of Cardiovascular Magnetic Resonance
https://read.qxmd.com/read/30612574/machine-learning-derived-segmentation-of-phase-velocity-encoded-cardiovascular-magnetic-resonance-for-fully-automated-aortic-flow-quantification
#9
Alex Bratt, Jiwon Kim, Meridith Pollie, Ashley N Beecy, Nathan H Tehrani, Noel Codella, Rocio Perez-Johnston, Maria Chiara Palumbo, Javid Alakbarli, Wayne Colizza, Ian R Drexler, Clerio F Azevedo, Raymond J Kim, Richard B Devereux, Jonathan W Weinsaft
BACKGROUND: Phase contrast (PC) cardiovascular magnetic resonance (CMR) is widely employed for flow quantification, but analysis typically requires time consuming manual segmentation which can require human correction. Advances in machine learning have markedly improved automated processing, but have yet to be applied to PC-CMR. This study tested a novel machine learning model for fully automated analysis of PC-CMR aortic flow. METHODS: A machine learning model was designed to track aortic valve borders based on neural network approaches...
January 7, 2019: Journal of Cardiovascular Magnetic Resonance
https://read.qxmd.com/read/30602395/prognostic-and-functional-implications-of-left-atrial-late-gadolinium-enhancement-cardiovascular-magnetic-resonance
#10
Michael Quail, Karl Grunseich, Lauren A Baldassarre, Hamid Mojibian, Mark A Marieb, Daniel Cornfeld, Aaron Soufer, Albert J Sinusas, Dana C Peters
BACKGROUND: Left atrial (LA) late gadolinium enhancement (LGE) on cardiovascular magnetic resonance (CMR) imaging is indicative of fibrosis, and has been correlated with reduced LA function, increased LA volume, and poor procedural outcomes in cohorts with atrial fibrillation (AF). However, the role of LGE as a prognostic biomarker for arrhythmia in cardiac disease has not been examined. METHODS: In this study, we assessed LA LGE using a 3D LGE CMR sequence to examine its relationships with new onset atrial arrhythmia, and LA and left ventricular (LV) mechanical function...
January 3, 2019: Journal of Cardiovascular Magnetic Resonance
https://read.qxmd.com/read/30602387/pelvic-cardiovascular-magnetic-resonance-venography-venous-changes-with-patient-position-and-hydration-status
#11
Ashkan H Behzadi, Neil M Khilnani, Weiguo Zhang, Amanda J Bares, Srikanth R Boddu, Robert J Min, Martin R Prince
BACKGROUND: To determine the effect of hydration as well as prone versus supine positioning on the pelvic veins during cardiovascular magnetic resonance (CMR) venography. METHODS: Under institutional review board approval, 8 healthy subjects were imaged with balanced steady state free precession, non-contrast CMR venography to measure common and external iliac vein volumes and common femoral vein cross-sectional area in the supine, prone and decubitus positions after dehydration and again following re-hydration...
January 3, 2019: Journal of Cardiovascular Magnetic Resonance
https://read.qxmd.com/read/30593280/journal-of-cardiovascular-magnetic-resonance-2017
#12
REVIEW
Warren J Manning
There were 106 articles published in the Journal of Cardiovascular Magnetic Resonance (JCMR) in 2017, including 92 original research papers, 3 reviews, 9 technical notes, and 1 Position paper, 1 erratum and 1 correction. The volume was similar to 2016 despite an increase in manuscript submissions to 405 and thus reflects a slight decrease in the acceptance rate to 26.7%. The quality of the submissions continues to be high. The 2017 JCMR Impact Factor (which is published in June 2018) was minimally lower at 5...
December 28, 2018: Journal of Cardiovascular Magnetic Resonance
https://read.qxmd.com/read/30580760/the-interplay-between-metabolic-alterations-diastolic-strain-rate-and-exercise-capacity-in-mild-heart-failure-with-preserved-ejection-fraction-a-cardiovascular-magnetic-resonance-study
#13
Masliza Mahmod, Nikhil Pal, Jennifer Rayner, Cameron Holloway, Betty Raman, Sairia Dass, Eylem Levelt, Rina Ariga, Vanessa Ferreira, Rajarshi Banerjee, Jurgen E Schneider, Christopher Rodgers, Jane M Francis, Theodoros D Karamitsos, Michael Frenneaux, Houman Ashrafian, Stefan Neubauer, Oliver Rider
BACKGROUND: Heart failure (HF) is characterized by altered myocardial substrate metabolism which can lead to myocardial triglyceride accumulation (steatosis) and lipotoxicity. However its role in mild HF with preserved ejection fraction (HFpEF) is uncertain. We measured myocardial triglyceride content (MTG) in HFpEF and assessed its relationships with diastolic function and exercise capacity. METHODS: Twenty seven HFpEF (clinical features of HF, left ventricular EF >50%, evidence of mild diastolic dysfunction and evidence of exercise limitation as assessed by cardiopulmonary exercise test) and 14 controls underwent 1 H-cardiovascular magnetic resonance spectroscopy (1 H-CMRS) to measure MTG (lipid/water, %), 31 P-CMRS to measure myocardial energetics (phosphocreatine-to-adenosine triphosphate - PCr/ATP) and feature-tracking cardiovascular magnetic resonance (CMR) imaging for diastolic strain rate...
December 24, 2018: Journal of Cardiovascular Magnetic Resonance
https://read.qxmd.com/read/30567577/aminophylline-shortage-and-current-recommendations-for-reversal-of-vasodilator-stress-an-asnc-information-statement-endorsed-by-scmr
#14
REVIEW
Aiden Abidov, Vasken Dilsizian, Rami Doukky, W Lane Duvall, Christopher Dyke, Michael D Elliott, Fadi G Hage, Milena J Henzlova, Nils P Johnson, Ronald G Schwartz, Gregory S Thomas, Andrew J Einstein
Pharmacologic reversal of serious or intolerable side effects (SISE) from vasodilator stress is an important safety and comfort measure for patients experiencing such effects. While typically performed using intravenous aminophylline, recurrent shortages of this agent have led to a greater need to limit its use and consider alternative agents. This information statement provides background and recommendations addressing indications for vasodilator reversal, timing of a reversal agent, incidence of observed SISE with vasodilator stress, clinical and logistical considerations for aminophylline-based reversal, and alternative non-aminophylline based reversal protocols...
December 20, 2018: Journal of Cardiovascular Magnetic Resonance
https://read.qxmd.com/read/30567572/dynamic-changes-in-injured-myocardium-very-early-after-acute-myocardial-infarction-quantified-using-t1-mapping-cardiovascular-magnetic-resonance
#15
Mohammad Alkhalil, Alessandra Borlotti, Giovanni Luigi De Maria, Lisa Gaughran, Jeremy Langrish, Andrew Lucking, Vanessa Ferreira, Rajesh K Kharbanda, Adrian P Banning, Keith M Channon, Erica Dall'Armellina, Robin P Choudhury
BACKGROUND: It has recently been suggested that myocardial oedema follows a bimodal pattern early post ST-segment elevation myocardial infarction (STEMI). Yet, water content, quantified using tissue desiccation, did not return to normal values unlike oedema quantified by cardiovascular magnetic resonance (CMR) imaging. We studied the temporal changes in the extent and intensity of injured myocardium using T1-mapping technique within the first week after STEMI. METHODS: A first group (n = 31) underwent 3 acute 3 T CMR scans (time-point (TP) < 3 h, 24 h and 6 days), including cine, native shortened modified look-locker inversion recovery T1 mapping, T2* mapping and late gadolinium enhancement (LGE)...
December 20, 2018: Journal of Cardiovascular Magnetic Resonance
https://read.qxmd.com/read/30567566/regional-assessment-of-carotid-artery-pulse-wave-velocity-using-compressed-sensing-accelerated-high-temporal-resolution-2d-cine-phase-contrast-cardiovascular-magnetic-resonance
#16
Eva S Peper, Gustav J Strijkers, Katja Gazzola, Wouter V Potters, Abdallah G Motaal, Ilse K Luirink, Barbara A Hutten, Albert Wiegman, Pim van Ooij, Bert-Jan H van den Born, Aart J Nederveen, Bram F Coolen
BACKGROUND: Cardiovascular magnetic resonance (CMR) allows for non-invasive assessment of arterial stiffness by means of measuring pulse wave velocity (PWV). PWV can be calculated from the time shift between two time-resolved flow curves acquired at two locations within an arterial segment. These flow curves can be derived from two-dimensional CINE phase contrast CMR (2D CINE PC CMR). While CMR-derived PWV measurements have proven to be accurate for the aorta, this is more challenging for smaller arteries such as the carotids due to the need for both high spatial and temporal resolution...
December 20, 2018: Journal of Cardiovascular Magnetic Resonance
https://read.qxmd.com/read/30558626/maldistribution-of-pulmonary-blood-flow-in-patients-after-the-fontan-operation-is-associated-with-worse-exercise-capacity
#17
Tarek Alsaied, Lynn A Sleeper, Marco Masci, Sunil J Ghelani, Nina Azcue, Tal Geva, Andrew J Powell, Rahul H Rathod
BACKGROUND: Maldistribution of pulmonary artery blood flow (MPBF) is a potential complication in patients who have undergone single ventricle palliation culminating in the Fontan procedure. Cardiovascular magnetic resonance (CMR) is the best modality that can evaluate MPBF in this population. The purpose of this study is to identify the prevalence and associations of MPBF and to determine the impact of MPBF on exercise capacity after the Fontan operation. METHODS: This retrospective single-center study included all patients after Fontan operation who had maximal cardiopulmonary exercise test (CPET) and CMR with flow measurements of the branch pulmonary arteries...
December 17, 2018: Journal of Cardiovascular Magnetic Resonance
https://read.qxmd.com/read/30554567/cardiovascular-magnetic-resonance-left-ventricular-strain-in-end-stage-renal-disease-patients-after-kidney-transplantation
#18
Inna Y Gong, Bandar Al-Amro, G V Ramesh Prasad, Philip W Connelly, Rachel M Wald, Ron Wald, Djeven P Deva, Howard Leong-Poi, Michelle M Nash, Weiqiu Yuan, Lakshman Gunaratnam, S Joseph Kim, Charmaine E Lok, Kim A Connelly, Andrew T Yan
BACKGROUND: Cardiovascular disease is a significant cause of morbidity and mortality in patients with end-stage renal disease (ESRD) and kidney transplant (KT) patients. Compared with left ventricular (LV) ejection fraction (LVEF), LV strain has emerged as an important marker of LV function as it is less load dependent. We sought to evaluate changes in LV strain using cardiovascular magnetic resonance imaging (CMR) in ESRD patients who received KT, to determine whether KT may improve LV function...
December 17, 2018: Journal of Cardiovascular Magnetic Resonance
https://read.qxmd.com/read/30541571/impaired-aortic-distensibility-and-elevated-central-blood-pressure-in-turner-syndrome-a-cardiovascular-magnetic-resonance-study
#19
Jan Wen, Christian Trolle, Mette H Viuff, Steffen Ringgaard, Esben Laugesen, Ephraim J Gutmark, Dhananjay Radhakrishnan Subramaniam, Philippe Backeljauw, Iris Gutmark-Little, Niels H Andersen, Kristian H Mortensen, Claus H Gravholt
BACKGROUND: Women with Turner Syndrome have an increased risk for aortic dissection. Arterial stiffening is a risk factor for aortic dilatation and dissection. Here we investigate if arterial stiffening can be observed in Turner Syndrome patients and is an initial step in the development of aortic dilatation and subsequent dissection. METHODS: Fifty-seven women with Turner Syndrome (48 years [29-66]) and thirty-six age- and sex-matched controls (49 years [26-68]) were included...
December 13, 2018: Journal of Cardiovascular Magnetic Resonance
https://read.qxmd.com/read/30526627/simultaneous-multi-slice-sms-balanced-steady-state-free-precession-first-pass-myocardial-perfusion-cardiovascular-magnetic-resonance-with-iterative-reconstruction-at-1-5-t
#20
Muhummad Sohaib Nazir, Radhouene Neji, Peter Speier, Fiona Reid, Daniel Stäb, Michaela Schmidt, Christoph Forman, Reza Razavi, Sven Plein, Tevfik F Ismail, Amedeo Chiribiri, Sébastien Roujol
BACKGROUND: Simultaneous-Multi-Slice (SMS) perfusion imaging has the potential to acquire multiple slices, increasing myocardial coverage without sacrificing in-plane spatial resolution. To maximise signal-to-noise ratio (SNR), SMS can be combined with a balanced steady state free precession (bSSFP) readout. Furthermore, application of gradient-controlled local Larmor adjustment (GC-LOLA) can ensure robustness against off-resonance artifacts and SNR loss can be mitigated by applying iterative reconstruction with spatial and temporal regularisation...
December 10, 2018: Journal of Cardiovascular Magnetic Resonance
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