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Journal of Clinical Densitometry

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https://read.qxmd.com/read/30744928/bone-health-in-patients-with-liver-diseases
#1
REVIEW
Christopher J Danford, Hirsh D Trivedi, Alan Bonder
Osteoporosis is the most common bone disease in chronic liver disease (CLD) resulting in frequent fractures and leading to significant morbidity in this population. In addition to patients with cirrhosis and chronic cholestasis, patients with CLD from other etiologies may be affected in the absence of cirrhosis. The mechanism of osteoporosis in CLD varies according to etiology, but in cirrhosis and cholestatic liver disease it is driven primarily by decreased bone formation, which differs from the increased bone resorption seen in postmenopausal osteoporosis...
January 18, 2019: Journal of Clinical Densitometry
https://read.qxmd.com/read/30691870/management-of-hip-fractures-at-an-academic-center-challenges-and-opportunities
#2
Randa Saad, Maya Beydoun, Ghada El-Hajj Fuleihan
OBJECTIVE: To assess characteristics of patients with hip fractures and investigate the extent of osteoporosis-related care they receive at a tertiary referral center in Lebanon. METHODS: A retrospective review of charts of 400 patients admitted with a hip fracture to the American University of Beirut-Medical Center, between January 1, 2011 and December 31, 2015. We reviewed medical records of adults admitted with a nonpathologic/nontraumatic hip fracture, and evaluated basic demographics and relevant clinical information, associated risk factors, and the management received...
January 6, 2019: Journal of Clinical Densitometry
https://read.qxmd.com/read/30661747/fat-mass-does-not-increase-the-precision-error-of-trabecular-bone-score-measurements
#3
Carmelo Messina, Ciriaco Buonomenna, Giorgia Menon, Sandro Magnani, Domenico Albano, Salvatore Gitto, Fabio Massimo Ulivieri, Luca Maria Sconfienza
INTRODUCTION: Trabecular bone score (TBS) is an indirect index of trabecular microarchitecture derived from lumbar spine dual-energy X-ray absorptiometry. Previous phantom study showed that an increase in soft tissue thickness does not affect TBS reproducibility. We investigated the effect of increasing body mass index (BMI) and waist circumference on TBS precision error on patients, compared to bone mineral density (BMD). METHODOLOGY: A population of postmenopausal Caucasian women was distributed in 3 different BMI (normal, overweight, and class I obesity), plus 2 further groups based on waist circumference diameter (≤88 cm and >88 cm, respectively)...
January 5, 2019: Journal of Clinical Densitometry
https://read.qxmd.com/read/30679114/the-water-fat-separation-method-for-determining-the-fat-free-component-of-subcutaneous-adipose-tissue-in-humans-a-brief-review
#4
REVIEW
Takashi Abe, Zachary W Bell, Scott J Dankel, Vickie Wong, Robert W Spitz, Jeremy P Loenneke
Fat-free mass as well as lean soft tissue mass is a surrogate for skeletal muscle mass and is often used for the normalization of several physiological variables or for the diagnosing of low muscle mass in older adults. However, both fat-free mass and lean tissue mass include nonskeletal muscle components such as the fat-free component of adipose tissue fat cells. A technique known as water-fat MRI provides a noninvasive and radiation-free assessment of the fat-free component of adipose tissue in humans. However, if this method is impractical or unavailable, some authors suggest that a constant value for the fat-free component of adipose tissue can be used as an indirect estimate...
December 22, 2018: Journal of Clinical Densitometry
https://read.qxmd.com/read/30655188/effect-of-sunlight-exposure-on-vitamin-d-status-of-individuals-living-in-a-nursing-home-and-their-own-homes
#5
F Okan, S Okan, H Zincir
INTRODUCTION/BACKGROUND: The present study was carried out to determine prevalence of vitamin D deficiency and related factors in individuals living in nursing home and their own homes. METHODOLOGY: This cross-sectional study included 72 elderly people 60 yr and older. All subjects were given a questionnaire form evaluating their individual characteristics, eating habits which affected their vitamin D status, wearing habits, and their duration of sun exposure and a Standardized Mini Mental Test evaluating their cognitive levels...
December 21, 2018: Journal of Clinical Densitometry
https://read.qxmd.com/read/30655187/hypophosphatasia-in-adults-clinical-spectrum-and-its-association-with-genetics-and-metabolic-substrates
#6
Eveline Lefever, Peter Witters, Evelien Gielen, Annick Vanclooster, Wouter Meersseman, Eva Morava, David Cassiman, Michaël R Laurent
BACKGROUND: Hypophosphatasia (HPP) is a rare metabolic bone disorder caused by mutations in the alkaline phosphatase (ALPL) gene, and characterized by low circulating alkaline phosphatase (ALP) levels and bone, muscle, dental and systemic manifestations. In this case series we investigate the clinical spectrum, genetic and biochemical profile of adult HPP patients from the University Hospitals Leuven, Belgium. METHODOLOGY: Adults with HPP were identified through medical record review...
December 21, 2018: Journal of Clinical Densitometry
https://read.qxmd.com/read/30665819/feasibility-of-opportunistic-screening-for-low-thoracic-bone-mineral-density-in-patients-referred-for-routine-cardiac-ct
#7
Josephine Therkildsen, Simon Winther, Louise Nissen, Hanne S Jørgensen, Jesper Thygesen, Per Ivarsen, Lars Frost, Bente L Langdahl, Ellen-Margrethe Hauge, Morten Böttcher
Despite being a frequent and treatable disease, osteoporosis remains under-diagnosed worldwide. Our study aim was to characterize the bone mineral density (BMD) status in a group of patients with symptoms suggestive of coronary artery disease (CAD) with low/intermediate risk profile undergoing routine cardiac computed tomography (CT) to rule out CAD. This cross-sectional study used prospectively acquired data from a large consecutively included cohort. Participants were referred for cardiac CT based on symptoms of CAD...
December 17, 2018: Journal of Clinical Densitometry
https://read.qxmd.com/read/30661746/statistical-models-to-assess-leg-muscle-mass-in-ambulatory-children-with-spastic-cerebral-palsy-using-dual-energy-x-ray-absorptiometry
#8
Chuan Zhang, Daniel G Whitney, Harshvardhan Singh, Jill M Slade, Ye Shen, Freeman Miller, Christopher M Modlesky
Cerebral palsy (CP) is a movement disorder associated with small and weak muscles. Methods that accurately assess muscle mass in children with CP are scarce. The purpose of this study was to determine whether dual-energy X-ray absorptiometry (DXA) accurately estimates midleg muscle mass in ambulatory children with spastic CP. Ambulatory children with spastic CP and typically developing children 5-11 y were studied (n = 15/group). Fat-free soft tissue mass (FFST) and fat mass at the middle third of the tibia (i...
December 15, 2018: Journal of Clinical Densitometry
https://read.qxmd.com/read/30638769/measurement-of-visceral-adipose-tissue-in-persons-with-spinal-cord-injury-by-magnetic-resonance-imaging-and-dual-x-ray-absorptiometry-generation-and-application-of-a-predictive-equation
#9
Liron S McCauley, Mina P Ghatas, Ryan M Sumrell, Christopher M Cirnigliaro, Steven C Kirshblum, William A Bauman, Ashraf S Gorgey
PURPOSE: Dual energy X-ray absorptiometry (DXA) and magnetic resonance imaging (MRI) permits quantification of visceral adipose tissue (VAT). However, DXA has not been validated against MRI in persons with chronic spinal cord injury (SCI). A predictive equation was generated from the measurement of VAT by MRI, a "gold" standard to quantitate VAT, compared to that of DXA, a method with several practical advantages. METHOD: DXA and MRI scans were performed in 27 participants with SCI...
December 15, 2018: Journal of Clinical Densitometry
https://read.qxmd.com/read/30583921/ct-based-evaluation-of-diffuse-idiopathic-skeletal-hyperostosis-in-adult-population-prevalence-associations-and-interobserver-agreement
#10
Hatem Adel, Sohail Ahmed Khan, Syed Omair Adil, Farheen Huda, Usman Khanzada, Murli Manohar, Kamran Masood
Diffuse idiopathic skeletal hyperostosis (DISH), being an asymptomatic condition, is generally discovered incidentally on imaging and it has not received much attention for research on clinical grounds. We assessed the prevalence of DISH, its associated factors, and interobserver agreement for computed tomography (CT)-based diagnosis of DISH. CT scans of chest, abdomen, and pelvis performed for various clinical indications were retrospectively reviewed. Resnick criteria were used for the diagnosis of DISH. Moreover, enthesopathy along with comorbidities was assessed...
December 6, 2018: Journal of Clinical Densitometry
https://read.qxmd.com/read/30658879/the-correction-of-systematic-error-due-to-plaster-and-fiberglass-casts-on-hr-pqct-bone-parameters-measured-in-vivo-at-the-distal-radius
#11
Danielle E Whittier, Sarah L Manske, Steven K Boyd, Prism S Schneider
Due to difficulty assessing healing of distal radius fractures using conventional radiography, there is interest in using high resolution peripheral quantitative computed tomography (HR-pQCT) to track healing at the microarchitectural level. Unfortunately, the plaster-of-Paris and fiberglass casts used to immobilize fractures affect HR-pQCT measurements due to beam hardening, and increased noise. The challenge is compounded because casts have variable thickness, and an individual patient will often have their cast changed 2-3 times during the course of treatment...
November 20, 2018: Journal of Clinical Densitometry
https://read.qxmd.com/read/29941355/glucocorticoid-induced-osteoporosis-management-challenges-in-older-patients
#12
REVIEW
Robert A Adler
Glucocorticoid-induced osteoporosis remains the most common type of secondary osteoporosis, mostly due to use of oral glucocorticoids rather than due to endogenous overproduction of cortisol. Partly because glucocorticoids are prescribed by a wide variety of clinicians for many different inflammatory disorders, only a minority of older individuals have adequate and timely assessment of their enhanced fracture risk, and fewer are offered treatment. Assessment should include bone density, the FRAX calculation, and, in many cases, images of the spine...
January 2019: Journal of Clinical Densitometry
https://read.qxmd.com/read/30503030/dxa-based-3d-analysis-of-the-cortical-and-trabecular-bone-of-hip-fracture-postmenopausal-women-a-case-control-study
#13
Ludovic Humbert, Alexis Bagué, Silvana Di Gregorio, Renaud Winzenrieth, Xavier Sevillano, Miguel Ángel González Ballester, Luis Del Rio
Methods using statistical shape and appearance models have been proposed to analyze bone mineral density (BMD) in 3D from dual energy X-ray absorptiometry (DXA) scans. This paper presents a retrospective case-control study assessing the association of DXA-derived 3D measurements with osteoporotic hip fracture in postmenopausal women. Patients who experienced a hip fracture between 1 and 6 years from baseline and age-matched controls were included in this study. The 3D-SHAPER software (version 2.7, Galgo Medical, Barcelona, Spain) was used to derive 3D analysis from hip DXA scans at baseline...
November 13, 2018: Journal of Clinical Densitometry
https://read.qxmd.com/read/30482496/bone-density-at-the-entry-point-correlates-with-the-trabecular-bone-of-the-thoracolumbar-vertebral-bodies-quantitative-computed-tomography-study
#14
Wojciech M Glinkowski, Jerzy Narloch
PURPOSE: To evaluate the relationship between cortical Bone Mineral Density (BMD) at pedicle entry points with trabecular BMD of the vertebral body in a spinal fracture. METHODS: Quantitative computed tomography of the thoracolumbar spine was analyzed using dedicated software - QCT Pro (Mindways, Austin, TX). RESULTS: Forty-six patients were evaluated. Among them 36 females were diagnosed with osteoporosis; the remaining 10 randomly selected from the database both males and females served as a control group...
November 9, 2018: Journal of Clinical Densitometry
https://read.qxmd.com/read/30482495/analysis-of-the-increase-in-bone-mineral-density-after-surgical-treatment-of-primary-hyperparathyroidism
#15
REVIEW
Fernando Mendoza-Moreno, Manuel Díez-Alonso, Enrique Ovejero-Merino, Ana Sánchez-Gollarte, Ricardo Alvarado-Hurtado, Belén Matías-García, Ángel Rodríguez-Pascual, Carlos Medina-Reinoso, Tomás Ratia-Jiménez, Francisco Hernández-Merlo, Javier Granell-Vicent
AIM: To analyze the effect of the surgery in bone mineral density (BMD) and to study the value of preoperative clinical and analytical factors as predictors of bone increase. MATERIAL AND METHODS: Prospective observational study. Postmenopausal women who were operated for primary hyperparathyroidism were included. A bone densitometry of the lumbar spine and femoral neck and analytical determinations (parathyroid hormone [PTH], alkaline phosphatase, albumin, phosphate, creatinine, 25-hydroxy-vitamin D3, creatinine clearance, and calciuria) were performed previous to the intervention and after 12 months from surgery...
November 9, 2018: Journal of Clinical Densitometry
https://read.qxmd.com/read/30527863/the-relationship-between-breast-density-bone-mineral-density-and-metabolic-syndrome-among-postmenopausal-turkish-women
#16
Meryem Kuru Pekcan, Rahime Bedir Findik, Aytekin Tokmak, Yasemin Taşçi
The relationship between metabolic syndrome (MetS) and menopause remains unclear. The effects of MetS on breast and bone density in this group of women are also not fully elucidated. Herein, we aimed to investigate the relationship between components of the MetS, mammographic breast density (MBD), and vertebral/femoral bone mineral density (BMD) in postmenopausal Turkish women. The study group consisted of postmenopausal women with MetS whereas controls postmenopausal women without MetS. All consecutive women who applied to our center for routine postmenopausal follow up and met the inclusion criteria, between July 2013 and October 2015 were included in the study...
November 8, 2018: Journal of Clinical Densitometry
https://read.qxmd.com/read/30472111/reliability-and-agreement-of-various-inbody-body-composition-analyzers-as-compared-to-dual-energy-x-ray-absorptiometry-in-healthy-men-and-women
#17
Cherilyn N McLester, Brett S Nickerson, Brian M Kliszczewicz, John R McLester
BACKGROUND: Bioelectrical impedance analysis has evolved over the years to include the use of multiple frequencies and impedance measurements to improve the accuracy and reliability of body composition estimates. The purpose of this investigation was to evaluate the reliability of the InBody230 , InBody720 , and InBody770 to measure body fat percent (BF%), fat mass (FM), and fat-free mass (FFM) in the general population and to compare results to dual-energy X-ray absorptiometry (DXA)...
November 3, 2018: Journal of Clinical Densitometry
https://read.qxmd.com/read/30503961/progressive-sublesional-bone-loss-extends-into-the-second-decade-after-spinal-cord-injury
#18
Christopher M Cirnigliaro, Mary Jane Myslinski, Pierre Asselin, Joshua C Hobson, Adam Specht, Michael F La Fountaine, Steven C Kirshblum, Gail F Forrest, Trevor Dyson-Hudson, Ann M Spungen, William A Bauman
OBJECTIVE: The rate of areal bone mineral density (aBMD) loss at the knee (distal femur (DF) and proximal tibia ) and hip (femoral neck (FN) and total hip (TH)) was determined in persons with traumatic spinal cord injury (SCI) who were stratified into subgroups based on time since injury (TSI). DESIGN: Cross-sectional retrospective review. SETTING: Department of Veterans Affairs Medical Center and Private Rehabilitation Hospital. PARTICIPANTS: Data on 105 individuals with SCI (TSI ≤12 months, n = 19; TSI 1-5 years, n = 35; 6-10 years, n = 19; TSI 11-20 years, n = 16; TSI >20 years, n = 15) and 17 able-bodied reference (ABref ) controls...
October 31, 2018: Journal of Clinical Densitometry
https://read.qxmd.com/read/30497868/frax-10-yr-fracture-risk-in-rheumatoid-arthritis-assessments-with-and-without-bone-mineral-density-may-lead-to-very-different-results-in-the-individual-patient
#19
Karen Dombestein Elde, Ole Rintek Madsen
OBJECTIVES: FRAX is a computer-based algorithm developed by the World Health Organisation for estimation of the 10-yr risk of a hip or major osteoporotic fracture. Inclusion of femoral neck bone mineral density (BMD) in the estimation is optional. The study aimed to investigate the intra-individual agreement between FRAX fracture risk calculated with and without BMD in patients with rheumatoid arthritis (RA). METHODS: Clinical data and BMD results from 50 RA patients registered in the Danish rheumatology registry (DANBIO) were used for analysis...
October 31, 2018: Journal of Clinical Densitometry
https://read.qxmd.com/read/30454952/same-day-vs-consecutive-day-precision-error-of-dual-energy-x-ray-absorptiometry-for-interpreting-body-composition-change-in-resistance-trained-athletes
#20
Adam J Zemski, Karen Hind, Shelley E Keating, Elizabeth M Broad, Damian J Marsh, Gary J Slater
The application of dual-energy X-ray absorptiometry (DXA) in sport science settings is gaining popularity due to its ability to assess body composition. The International Society for Clinical Densitometry (ISCD) recommends application of the least significant change (LSC) to interpret meaningful and true change. This is calculated from same-day consecutive scans, thus accounting for technical error. However, this approach does not capture biological variation, which is pertinent when interpreting longitudinal measurements, and could be captured from consecutive-day scans...
October 29, 2018: Journal of Clinical Densitometry
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