Savini Thrikawala, Fahmi Mesmar, Beas Bhattacharya, Maram Muhsen, Srijita Mukhopadhyay, Sara Flores, Sanat Upadhyay, Leoncio Vergara, Jan-Åke Gustafsson, Cecilia Williams, Maria Bondesson
Triazoles are a major group of azole fungicides commonly used in agriculture, veterinary, and human medicine. Maternal exposure to certain triazole anti-fungal medication causes congenital malformations, including skeletal malformations. We hypothesized that triazoles used as pesticides in agriculture also pose a risk of causing skeletal malformations in developing embryos. In this study, teratogenic effects of three commonly used triazoles, cyproconazole, paclobutrazol, and triadimenol, were investigated in zebrafish, Danio rerio...
March 23, 2023: Toxicological Sciences: An Official Journal of the Society of Toxicology