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Journals Critical Care : the Official J...

Critical Care : the Official Journal of the Critical Care Forum

https://read.qxmd.com/read/37237410/variation-in-central-venous-oxygen-saturation-to-evaluate-fluid-responsiveness-a-systematic-review-and-meta-analysis
#1
JOURNAL ARTICLE
Jianneng Pan, Yuxiang Sun, Zhaojun Xu, Pingping Dong, Xiaoyang Zhou
BACKGROUND: Since oxygen content and oxygen consumption typically remain unchanged within a short period, variation in central venous oxygen saturation (ΔScvO2 ) during fluid challenge can theoretically track the changes in cardiac output (CO). We conducted this meta-analysis to systematically assess the diagnostic performance of ΔScvO2 during a fluid challenge for fluid responsiveness in mechanically ventilated patients receiving volume expansion. METHODS: Electronic databases were systematically searched to identify relevant studies published before October 24, 2022...
May 26, 2023: Critical Care: the Official Journal of the Critical Care Forum
https://read.qxmd.com/read/37237403/sodium-glucose-co-transporter-2-inhibitors-in-the-intensive-care-unit-setting-do-we-really-need-sodium-increase-especially-in-sepsis
#2
LETTER
Dimitrios Patoulias
No abstract text is available yet for this article.
May 26, 2023: Critical Care: the Official Journal of the Critical Care Forum
https://read.qxmd.com/read/37237395/correction-epidemiology-and-outcomes-of-early-onset-aki-in-covid-19-related-ards-in-comparison-with-non-covid-19-related-ards-insights-from-two-prospective-global-cohort-studies
#3
Bairbre A McNicholas, Emanuele Rezoagli, Andrew J Simpkin, Sankalp Khanna, Jacky Y Suen, Pauline Yeung, Daniel Brodie, Gianluigi Li Bassi, Tai Pham, Giacomo Bellani, John F Fraser, John Laffey
No abstract text is available yet for this article.
May 26, 2023: Critical Care: the Official Journal of the Critical Care Forum
https://read.qxmd.com/read/37237315/correlation-between-the-vexus-score-and-right-atrial-pressure-a-pilot-prospective-observational-study
#4
JOURNAL ARTICLE
August Longino, Katharine Martin, Katarina Leyba, Gabriel Siegel, Edward Gill, Ivor S Douglas, Joseph Burke
Venous congestion is an under-recognized contributor to mortality in critically ill patients. Unfortunately, venous congestion is difficult to measure, and right heart catheterization (RHC) has been considered the most readily available means for measuring venous filling pressure. Recently, a novel "Venous Excess Ultrasound (VExUS)" score was developed to noninvasively quantify venous congestion using inferior vena cava (IVC) diameter and Doppler flow through the hepatic, portal, and renal veins. A preliminary retrospective study of post-cardiac surgery patients showed promising results, including a high positive-likelihood ratio of high VExUS grade for acute kidney injury...
May 26, 2023: Critical Care: the Official Journal of the Critical Care Forum
https://read.qxmd.com/read/37237287/a-deep-learning-model-enables-accurate-prediction-and-quantification-of-pulmonary-edema-from-chest-x-rays
#5
JOURNAL ARTICLE
Dominik Schulz, Sebastian Rasch, Markus Heilmaier, Rami Abbassi, Alexander Poszler, Jörg Ulrich, Manuel Steinhardt, Georgios A Kaissis, Roland M Schmid, Rickmer Braren, Tobias Lahmer
BACKGROUND: A quantitative assessment of pulmonary edema is important because the clinical severity can range from mild impairment to life threatening. A quantitative surrogate measure, although invasive, for pulmonary edema is the extravascular lung water index (EVLWI) extracted from the transpulmonary thermodilution (TPTD). Severity of edema from chest X-rays, to date is based on the subjective classification of radiologists. In this work, we use machine learning to quantitatively predict the severity of pulmonary edema from chest radiography...
May 26, 2023: Critical Care: the Official Journal of the Critical Care Forum
https://read.qxmd.com/read/37231510/diagnostic-accuracy-of-point-of-care-ultrasound-for-shock-a-systematic-review-and-meta-analysis
#6
REVIEW
Takuo Yoshida, Takuya Yoshida, Hisashi Noma, Takeshi Nomura, Akihiro Suzuki, Takahiro Mihara
BACKGROUND:  Circulatory failure is classified into four types of shock (obstructive, cardiogenic, distributive, and hypovolemic) that must be distinguished as each requires a different treatment. Point-of-care ultrasound (POCUS) is widely used in clinical practice for acute conditions, and several diagnostic protocols using POCUS for shock have been developed. This study aimed to evaluate the diagnostic accuracy of POCUS in identifying the etiology of shock. METHODS: We conducted a systematic literature search of MEDLINE, Cochrane Central Register of Controlled Trials, Embase, Web of Science, Clinicaltrial...
May 25, 2023: Critical Care: the Official Journal of the Critical Care Forum
https://read.qxmd.com/read/37226261/prevalence-and-risk-factors-of-significant-persistent-pain-symptoms-after-critical-care-illness-a-prospective-multicentric-study
#7
JOURNAL ARTICLE
Alexandre Bourdiol, Vincent Legros, Fanny Vardon-Bounes, Thomas Rimmele, Paul Abraham, Clément Hoffmann, Claire Dahyot-Fizelier, Maud Jonas, Pierre Bouju, Cédric Cirenei, Yoann Launey, Gregoire Le Gac, Samia Boubeche, Edouard Lamarche, Olivier Huet, Lucillia Bezu, Julie Darrieussecq, Magdalena Szczot, Agathe Delbove, Johan Schmitt, Sigismond Lasocki, Johann Auchabie, Ludivine Petit, Emmanuelle Kuhn-Bougouin, Karim Asehnoune, Hugo Ingles, Antoine Roquilly, Raphaël Cinotti
BACKGROUND: Prevalence, risk factors and medical management of persistent pain symptoms after critical care illness have not been thoroughly investigated. METHODS: We performed a prospective multicentric study in patients with an intensive care unit (ICU) length of stay ≥ 48 h. The primary outcome was the prevalence of significant persistent pain, defined as a numeric rating scale (NRS) ≥ 3, 3 months after admission...
May 25, 2023: Critical Care: the Official Journal of the Critical Care Forum
https://read.qxmd.com/read/37226253/comment-to-propofol-and-survival-an-updated-meta-analysis-of-randomized-clinical-trials
#8
LETTER
David Benavides-Zora, Jose Hugo Arias-Botero
No abstract text is available yet for this article.
May 24, 2023: Critical Care: the Official Journal of the Critical Care Forum
https://read.qxmd.com/read/37218012/fibroblast-growth-factor-21-attenuates-ventilator-induced-lung-injury-by-inhibiting-the-nlrp3-caspase-1-gsdmd-pyroptotic-pathway
#9
JOURNAL ARTICLE
Peng Ding, Rui Yang, Cheng Li, Hai-Long Fu, Guang-Li Ren, Pei Wang, Dong-Yu Zheng, Wei Chen, Li-Ye Yang, Yan-Fei Mao, Hong-Bin Yuan, Yong-Hua Li
BACKGROUND: Ventilator-induced lung injury (VILI) is caused by overdistension of the alveoli by the repetitive recruitment and derecruitment of alveolar units. This study aims to investigate the potential role and mechanism of fibroblast growth factor 21 (FGF21), a metabolic regulator secreted by the liver, in VILI development. METHODS: Serum FGF21 concentrations were determined in patients undergoing mechanical ventilation during general anesthesia and in a mouse VILI model...
May 22, 2023: Critical Care: the Official Journal of the Critical Care Forum
https://read.qxmd.com/read/37218008/limitation-of-life%C3%A2-sustaining-therapies-in-critically-ill-patients-with-covid%C3%A2-19-what-lessons-to-draw
#10
LETTER
Nicolas Engrand, Armelle Nicolas-Robin
No abstract text is available yet for this article.
May 22, 2023: Critical Care: the Official Journal of the Critical Care Forum
https://read.qxmd.com/read/37217944/pupillary-dysfunction-during-hypothermic-circulatory-arrest-insights-from-automated-pupillometry
#11
LETTER
Lorenzo Peluso, Federica Baccanelli, Valentina Grazioli, Paolo Panisi, Fabio Silvio Taccone, Giovanni Albano
No abstract text is available yet for this article.
May 22, 2023: Critical Care: the Official Journal of the Critical Care Forum
https://read.qxmd.com/read/37210541/biomarker-based-risk-model-to-predict-persistent-multiple-organ-dysfunctions-after-congenital-heart-surgery-a-prospective-observational-cohort-study
#12
JOURNAL ARTICLE
Alexis L Benscoter, Jeffrey A Alten, Mihir R Atreya, David S Cooper, Jonathan W Byrnes, David P Nelson, Nicholas J Ollberding, Hector R Wong
BACKGROUND: Multiple organ dysfunction syndrome (MODS) is an important cause of post-operative morbidity and mortality for children undergoing cardiac surgery requiring cardiopulmonary bypass (CPB). Dysregulated inflammation is widely regarded as a key contributor to bypass-related MODS pathobiology, with considerable overlap of pathways associated with septic shock. The pediatric sepsis biomarker risk model (PERSEVERE) is comprised of seven protein biomarkers of inflammation and reliably predicts baseline risk of mortality and organ dysfunction among critically ill children with septic shock...
May 20, 2023: Critical Care: the Official Journal of the Critical Care Forum
https://read.qxmd.com/read/37210526/the-lower-limit-of-reactivity-as-a-potential-individualised-cerebral-perfusion-pressure-target-in-traumatic-brain-injury-a-center-tbi-high-resolution-sub-study-analysis
#13
JOURNAL ARTICLE
Erta Beqiri, Frederick A Zeiler, Ari Ercole, Michal M Placek, Jeanette Tas, Joseph Donnelly, Marcel J H Aries, Peter J Hutchinson, David Menon, Nino Stocchetti, Marek Czosnyka, Peter Smielewski
BACKGROUND: A previous retrospective single-centre study suggested that the percentage of time spent with cerebral perfusion pressure (CPP) below the individual lower limit of reactivity (LLR) is associated with mortality in traumatic brain injury (TBI) patients. We aim to validate this in a large multicentre cohort. METHODS: Recordings from 171 TBI patients from the high-resolution cohort of the CENTER-TBI study were processed with ICM+ software. We derived LLR as a time trend of CPP at a level for which the pressure reactivity index (PRx) indicates impaired cerebrovascular reactivity with low CPP...
May 20, 2023: Critical Care: the Official Journal of the Critical Care Forum
https://read.qxmd.com/read/37198651/reply-to-propofol-and-survival-an-updated-meta%C3%A2-analysis-of-randomized-clinical-trials
#14
LETTER
Manuel Alberto Guerrero Gutierrez, José A Meade-Aguilar, Diego Escarraman Martinez
No abstract text is available yet for this article.
May 17, 2023: Critical Care: the Official Journal of the Critical Care Forum
https://read.qxmd.com/read/37198634/can-fluid-responsiveness-tests-utilizing-positive-end-expiratory-pressure-changes-be-adapted-to-improve-applicability-in-all-mechanically-ventilated-patients
#15
LETTER
Camilo Pérez, Laura Castillo, Jorge Alvarado
No abstract text is available yet for this article.
May 17, 2023: Critical Care: the Official Journal of the Critical Care Forum
https://read.qxmd.com/read/37194077/sodium-glucose-co-transporter-2-inhibitors-in-intensive-care-unit-patients-with-type-2-diabetes-a-pilot-case-control-study
#16
JOURNAL ARTICLE
Johan Mårtensson, Salvatore Lucio Cutuli, Eduardo A Osawa, Fumitaka Yanase, Lisa Toh, Luca Cioccari, Nora Luethi, Akinori Maeda, Rinaldo Bellomo
BACKGROUND: Sodium glucose co-transporter-2 (SGLT2) inhibitors improve long-term cardiovascular and renal outcomes in individuals with type 2 diabetes. However, the safety of SGLT2 inhibitors in ICU patients with type 2 diabetes is uncertain. We aimed to perform a pilot study to assess the relationship between empagliflozin therapy and biochemical, and clinical outcomes in such patients. METHODS: We included 18 ICU patients with type 2 diabetes receiving empagliflozin (10 mg daily) and insulin to target glucose range of 10-14 mmol/l according to our liberal glucose control protocol for patients with diabetes (treatment group)...
May 16, 2023: Critical Care: the Official Journal of the Critical Care Forum
https://read.qxmd.com/read/37193993/the-future-of-intensive-care-the-study-of-the-microcirculation-will-help-to-guide-our-therapies
#17
REVIEW
J Duranteau, D De Backer, K Donadello, N I Shapiro, S D Hutchings, A Rovas, M Legrand, A Harrois, C Ince
The goal of hemodynamic resuscitation is to optimize the microcirculation of organs to meet their oxygen and metabolic needs. Clinicians are currently blind to what is happening in the microcirculation of organs, which prevents them from achieving an additional degree of individualization of the hemodynamic resuscitation at tissue level. Indeed, clinicians never know whether optimization of the microcirculation and tissue oxygenation is actually achieved after macrovascular hemodynamic optimization. The challenge for the future is to have noninvasive, easy-to-use equipment that allows reliable assessment and immediate quantitative analysis of the microcirculation at the bedside...
May 16, 2023: Critical Care: the Official Journal of the Critical Care Forum
https://read.qxmd.com/read/37189180/confounding-factors-in-article-stating-that-ubiquitin-c-terminal-hydrolase-predicts-poor-neurological-outcome-after-cardiac-arrest
#18
LETTER
Patrick M Honoré, Emily Perriens, Ibrahim Bousbiat, Nahida Harim, Elena Germain, Patrick El Nawar, Sydney Blackman
No abstract text is available yet for this article.
May 15, 2023: Critical Care: the Official Journal of the Critical Care Forum
https://read.qxmd.com/read/37189173/objective-and-subjective-cognition-in-survivors-of-covid-19-one-year-after-icu-discharge-the-role-of-demographic-clinical-and-emotional-factors
#19
JOURNAL ARTICLE
Marta Godoy-González, Guillem Navarra-Ventura, Gemma Gomà, Candelaria de Haro, Cristina Espinal, Cristina Fortià, Natalia Ridao, Nuria Miguel Rebanal, Laia Oliveras-Furriols, Carles Subirà, Mercè Jodar, Verónica Santos-Pulpón, Leonardo Sarlabous, Rafael Fernández, Ana Ochagavía, Lluís Blanch, Oriol Roca, Josefina López-Aguilar, Sol Fernández-Gonzalo
BACKGROUND: Intensive Care Unit (ICU) COVID-19 survivors may present long-term cognitive and emotional difficulties after hospital discharge. This study aims to characterize the neuropsychological dysfunction of COVID-19 survivors 12 months after ICU discharge, and to study whether the use of a measure of perceived cognitive deficit allows the detection of objective cognitive impairment. We also explore the relationship between demographic, clinical and emotional factors, and both objective and subjective cognitive deficits...
May 15, 2023: Critical Care: the Official Journal of the Critical Care Forum
https://read.qxmd.com/read/37179324/icu-without-borders
#20
REVIEW
Marlies Ostermann, Jean-Louis Vincent
Critical illness is a continuum, but patient care is often fragmented. Value-based critical care focuses on the overall health of the patient, not on an episode of care. The "ICU without borders" model incorporates a concept where members of the critical care team are involved in the management of patients from the onset of critical illness until recovery and beyond. In this paper, we summarise the potential benefits and challenges to patients, families, staff and the wider healthcare system and list some essential requirements, including a tight governance framework, advanced technologies, investment and trust...
May 13, 2023: Critical Care: the Official Journal of the Critical Care Forum
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