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Journals Critical Care : the Official J...

Critical Care : the Official Journal of the Critical Care Forum

https://read.qxmd.com/read/38041199/effects-of-lower-versus-higher-oxygen-targets-on-out-of-hospital-cardiac-arrest
#1
LETTER
Yang Zhao, Qian Wang, Bin Zang
No abstract text is available yet for this article.
December 1, 2023: Critical Care: the Official Journal of the Critical Care Forum
https://read.qxmd.com/read/38041177/dysnatremia-at-icu-admission-and-functional-outcome-of-cardiac-arrest-insights-from-four-randomised-controlled-trials
#2
JOURNAL ARTICLE
Jean Baptiste Lascarrou, Cyrielle Ermel, Alain Cariou, Timo Laitio, Hans Kirkegaard, Eldar Søreide, Anders M Grejs, Matti Reinikainen, Gwenhael Colin, Fabio Silvio Taccone, Amélie Le Gouge, Markus B Skrifvars
PURPOSE: To evaluate the potential association between early dysnatremia and 6-month functional outcome after cardiac arrest. METHODS: We pooled data from four randomised clinical trials in post-cardiac-arrest patients admitted to the ICU with coma after stable return of spontaneous circulation (ROSC). Admission natremia was categorised as normal (135-145 mmol/L), low, or high. We analysed associations between natremia category and Cerebral Performance Category (CPC) 1 or 2 at 6 months, with and without adjustment on the modified Cardiac Arrest Hospital Prognosis Score (mCAHP)...
December 1, 2023: Critical Care: the Official Journal of the Critical Care Forum
https://read.qxmd.com/read/38037130/combination-of-serum-and-peritoneal-1-3-beta-d-glucan-can-rule-out-intra-abdominal-candidiasis-in-surgical-critically-ill-patients-a-multicenter-prospective-study
#3
JOURNAL ARTICLE
Emmanuel Novy, Jérémie Rivière, Maxime Nguyen, Gaëlle Arfeuille, Guillaume Louis, Bélaïd Bouhemad, Julien Pottecher, Stéphane Hecketsweiler, Adeline Germain, François-Xavier Laithier, Marie-Reine Losser, Anne Debourgogne, Yohann Bernard, Hélène Rousseau, Cédric Baumann, Amandine Luc, Julien Birckener, Marie-Claire Machouart, Philippe Guerci
BACKGROUND: Intra-abdominal candidiasis (IAC) is difficult to predict in critically ill patients with intra-abdominal infection, leading to the overuse of antifungal treatments. Serum and peritoneal 1.3-beta-D-glucan (sBDG and pBDG) have been proposed to confirm or invalidate the diagnosis of IAC, but clinical studies have reported inconsistent results, notably because of heterogeneous populations with a low IAC prevalence. This study aimed to identify a high-risk IAC population and evaluate pBDG and sBDG in diagnosing IAC...
November 30, 2023: Critical Care: the Official Journal of the Critical Care Forum
https://read.qxmd.com/read/38037118/prognostic-differences-in-sepsis-caused-by-gram-negative-bacteria-and-gram-positive-bacteria-a-systematic-review-and-meta-analysis
#4
JOURNAL ARTICLE
Aling Tang, Yi Shi, Qingqing Dong, Sihui Wang, Yao Ge, Chenyan Wang, Zhimin Gong, Weizhen Zhang, Wei Chen
BACKGROUND: Bacteria are the main pathogens that cause sepsis. The pathogenic mechanisms of sepsis caused by gram-negative and gram-positive bacteria are completely different, and their prognostic differences in sepsis remain unclear. METHODS: The PubMed, Web of Science, Cochrane Library, and Embase databases were searched for Chinese and English studies (January 2003 to September 2023). Observational studies involving gram-negative (G (-))/gram-positive (G (+)) bacterial infection and the prognosis of sepsis were included...
November 30, 2023: Critical Care: the Official Journal of the Critical Care Forum
https://read.qxmd.com/read/38037109/publisher-correction-to-critical-illness-weakness-polyneuropathy-and-myopathy-diagnosis-treatment-and-long%C3%A2-term-outcomes
#5
Nicola Latronico, Frank A Rasulo, Matthias Eikermann, Simone Piva
No abstract text is available yet for this article.
November 30, 2023: Critical Care: the Official Journal of the Critical Care Forum
https://read.qxmd.com/read/38037056/the-use-of-checklists-in-the-intensive-care-unit-a-scoping-review
#6
REVIEW
Ethan J Erikson, Daniel A Edelman, Fiona M Brewster, Stuart D Marshall, Maryann C Turner, Vineet V Sarode, David J Brewster
BACKGROUND: Despite the extensive volume of research published on checklists in the intensive care unit (ICU), no review has been published on the broader role of checklists within the intensive care unit, their implementation and validation, and the recommended clinical context for their use. Accordingly, a scoping review was necessary to map the current literature and to guide future research on intensive care checklists. This review focuses on what checklists are currently used, how they are used, process of checklist development and implementation, and outcomes associated with checklist use...
November 30, 2023: Critical Care: the Official Journal of the Critical Care Forum
https://read.qxmd.com/read/38031116/estimation-of-inspiratory-effort-using-airway-occlusion-maneuvers-in-ventilated-children-a-secondary-analysis-of-an-ongoing-randomized-trial-testing-a-lung-and-diaphragm-protective-ventilation-strategy
#7
RANDOMIZED CONTROLLED TRIAL
Yukie Ito, Matías G Herrera, Justin C Hotz, Miyako Kyogoku, Christopher J L Newth, Anoopindar K Bhalla, Muneyuki Takeuchi, Robinder G Khemani
BACKGROUND: Monitoring respiratory effort in ventilated patients is important to balance lung and diaphragm protection. Esophageal manometry remains the gold standard for monitoring respiratory effort but is invasive and requires expertise for its measurement and interpretation. Airway pressures during occlusion maneuvers may provide an alternative, although pediatric data are limited. We sought to determine the correlation between change in esophageal pressure during tidal breathing (∆Pes) and airway pressure measured during three airway occlusion maneuvers: (1) expiratory occlusion pressure (Pocc), (2) airway occlusion pressure (P0...
November 29, 2023: Critical Care: the Official Journal of the Critical Care Forum
https://read.qxmd.com/read/38017578/external-validation-of-the-modified-sepsis-renal-angina-index-for-prediction-of-severe-acute-kidney-injury-in-children-with-septic-shock
#8
JOURNAL ARTICLE
Natalja L Stanski, Rajit K Basu, Natalie Z Cvijanovich, Julie C Fitzgerald, Michael T Bigham, Parag N Jain, Adam J Schwarz, Riad Lutfi, Neal J Thomas, Torrey Baines, Bereketeab Haileselassie, Scott L Weiss, Mihir R Atreya, Andrew J Lautz, Basilia Zingarelli, Stephen W Standage, Jennifer Kaplan, Lakhmir S Chawla, Stuart L Goldstein
BACKGROUND: Acute kidney injury (AKI) occurs commonly in pediatric septic shock and increases morbidity and mortality. Early identification of high-risk patients can facilitate targeted intervention to improve outcomes. We previously modified the renal angina index (RAI), a validated AKI prediction tool, to improve specificity in this population (sRAI). Here, we prospectively assess sRAI performance in a separate cohort. METHODS: A secondary analysis of a prospective, multicenter, observational study of children with septic shock admitted to the pediatric intensive care unit from 1/2019 to 12/2022...
November 28, 2023: Critical Care: the Official Journal of the Critical Care Forum
https://read.qxmd.com/read/38017475/positive-single-center-randomized-trials-and-subsequent-multicenter-randomized-trials-in-critically-ill-patients-a-systematic-review
#9
JOURNAL ARTICLE
Yuki Kotani, Stefano Turi, Alessandro Ortalda, Martina Baiardo Redaelli, Cristiano Marchetti, Giovanni Landoni, Rinaldo Bellomo
BACKGROUND: It is unclear how often survival benefits observed in single-center randomized controlled trials (sRCTs) involving critically ill patients are confirmed by subsequent multicenter randomized controlled trials (mRCTs). We aimed to perform a systemic literature review of sRCTs with a statistically significant mortality reduction and to evaluate whether subsequent mRCTs confirmed such reduction. METHODS: We searched PubMed for sRCTs published in the New England Journal of Medicine, JAMA, or Lancet, from inception until December 31, 2016...
November 28, 2023: Critical Care: the Official Journal of the Critical Care Forum
https://read.qxmd.com/read/38017441/response-to-comment-on-human-cytomegalovirus-seropositivity-is-associated-with-reduced-patient-survival-during-sepsis
#10
LETTER
Björn Koos, Matthias Unterberg, Tim Rahmel, Michael Adamzik, Stefan F Ehrentraut
No abstract text is available yet for this article.
November 28, 2023: Critical Care: the Official Journal of the Critical Care Forum
https://read.qxmd.com/read/38012797/an-international-rand-ucla-expert-panel-to-determine-the-optimal-diagnosis-and-management-of-burn-inhalation-injury
#11
JOURNAL ARTICLE
Helena Milton-Jones, Sabri Soussi, Roger Davies, Emmanuel Charbonney, Walton N Charles, Heather Cleland, Ken Dunn, Dashiell Gantner, Julian Giles, Marc Jeschke, Nicole Lee, Matthieu Legrand, Joanne Lloyd, Ignacio Martin-Loeches, Olivier Pantet, Mark Samaan, Odhran Shelley, Alice Sisson, Kaisa Spragg, Fiona Wood, Jeremy Yarrow, Marcela Paola Vizcaychipi, Andrew Williams, Jorge Leon-Villapalos, Declan Collins, Isabel Jones, Suveer Singh
BACKGROUND: Burn inhalation injury (BII) is a major cause of burn-related mortality and morbidity. Despite published practice guidelines, no consensus exists for the best strategies regarding diagnosis and management of BII. A modified DELPHI study using the RAND/UCLA (University of California, Los Angeles) Appropriateness Method (RAM) systematically analysed the opinions of an expert panel. Expert opinion was combined with available evidence to determine what constitutes appropriate and inappropriate judgement in the diagnosis and management of BII...
November 27, 2023: Critical Care: the Official Journal of the Critical Care Forum
https://read.qxmd.com/read/38012789/extending-the-host-response-paradigm-from-sepsis-to-cardiogenic-shock-evidence-limitations-and-opportunities
#12
REVIEW
Marie Buckel, Patrick Maclean, Julian C Knight, Patrick R Lawler, Alastair G Proudfoot
Recent clinical and research efforts in cardiogenic shock (CS) have largely focussed on the restoration of the low cardiac output state that is the conditio sine qua non of the clinical syndrome. This approach has failed to translate into improved outcomes, and mortality has remained static at 30-50%. There is an unmet need to better delineate the pathobiology of CS to understand the observed heterogeneity of presentation and treatment effect and to identify novel therapeutic targets. Despite data in other critical illness syndromes, specifically sepsis, the role of dysregulated inflammation and immunity is hitherto poorly described in CS...
November 27, 2023: Critical Care: the Official Journal of the Critical Care Forum
https://read.qxmd.com/read/38012768/evaluation-of-the-sensory-environment-in-a-large-tertiary-icu
#13
JOURNAL ARTICLE
Oystein Tronstad, Dylan Flaws, Sue Patterson, Robert Holdsworth, Veronica Garcia-Hansen, Francisca Rodriguez Leonard, Ruth Ong, Stephanie Yerkovich, John F Fraser
BACKGROUND: ICU survival is improving. However, many patients leave ICU with ongoing cognitive, physical, and/or psychological impairments and reduced quality of life. Many of the reasons for these ongoing problems are unmodifiable; however, some are linked with the ICU environment. Suboptimal lighting and excessive noise contribute to a loss of circadian rhythms and sleep disruptions, leading to increased mortality and morbidity. Despite long-standing awareness of these problems, meaningful ICU redesign is yet to be realised, and the 'ideal' ICU design is likely to be unique to local context and patient cohorts...
November 27, 2023: Critical Care: the Official Journal of the Critical Care Forum
https://read.qxmd.com/read/38012731/effects-of-early-versus-delayed-application-of-prone-position-on-ventilation-perfusion-mismatch-in-patients-with-acute-respiratory-distress-syndrome-a-prospective-observational-study
#14
JOURNAL ARTICLE
Xueyan Yuan, Zhanqi Zhao, Yali Chao, Dongyu Chen, Hui Chen, Rui Zhang, Songqiao Liu, Jianfeng Xie, Yi Yang, Haibo Qiu, Leo Heunks, Ling Liu
BACKGROUND: Prone position has been shown to improve oxygenation and survival in patients with early acute respiratory distress syndrome (ARDS). These beneficial effects are partly mediated by improved ventilation/perfusion (V/Q) distribution. Few studies have investigated the impact of early versus delayed proning on V/Q distribution in patients with ARDS. The aim of this study was to assess the regional ventilation and perfusion distribution in early versus persistent ARDS after prone position...
November 27, 2023: Critical Care: the Official Journal of the Critical Care Forum
https://read.qxmd.com/read/38001494/neutralization-of-extracellular-histones-by-sodium-%C3%AE-o-methyl-cellobioside-sulfate-in-septic-shock
#15
JOURNAL ARTICLE
Bruno Garcia, Fuhong Su, Laurence Dewachter, Yong Wang, Ning Li, Myriam Remmelink, Marie Van Eycken, Amina Khaldi, Raphaël Favory, Antoine Herpain, Anthony Moreau, Alexander Moiroux-Sahraoui, Francesca Manicone, Filippo Annoni, Lin Shi, Jean-Louis Vincent, Jacques Creteur, Fabio S Taccone
BACKGROUND: Extracellular histones have been associated with severity and outcome in sepsis. The aim of the present study was to assess the effects of sodium-β-O-Methyl cellobioside sulfate (mCBS), a histone-neutralizing polyanion, on the severity and outcome of sepsis in an experimental model. METHODS: This randomized placebo-controlled experimental study was performed in 24 mechanically ventilated female sheep. Sepsis was induced by fecal peritonitis. Animals were randomized to three groups: control, early treatment, and late treatment (n = 8 each)...
November 24, 2023: Critical Care: the Official Journal of the Critical Care Forum
https://read.qxmd.com/read/38001485/dynamic-relative-regional-lung-strain-estimated-by-computed-tomography-and-electrical-impedance-tomography-in-ards-patients
#16
JOURNAL ARTICLE
Roberto Brito, Caio C A Morais, Marioli T Lazo, Dannette V Guiñez, Abraham I J Gajardo, Daniel H Arellano, Marcelo B P Amato, Rodrigo A Cornejo
BACKGROUND: In the acute distress respiratory syndrome (ARDS), specific lung regions can be exposed to excessive strain due to heterogeneous disease, gravity-dependent lung collapse and injurious mechanical ventilation. Computed tomography (CT) is the gold standard for regional strain assessment. An alternative tool could be the electrical impedance tomography (EIT). We aimed to determine whether EIT-based methods can predict the dynamic relative regional strain (DRRS) between two levels of end-expiratory pressure (PEEP) in gravity-non-dependent and dependent lung regions...
November 24, 2023: Critical Care: the Official Journal of the Critical Care Forum
https://read.qxmd.com/read/37996945/safety-of-interhospital-transfer-for-critically-ill-covid-19-patients
#17
LETTER
Fabian Perschinka, Helmut Niedermoser, Andreas Peer, Georg Franz Lehner, Timo Mayerhöfer, Viktor Stöllnberger, Dietmar Fries, Michael Joannidis
No abstract text is available yet for this article.
November 23, 2023: Critical Care: the Official Journal of the Critical Care Forum
https://read.qxmd.com/read/37990329/critical-appraisal-and-concerns-regarding-a-meta-analysis-on-prothrombin-complex-concentrate-pcc-for-trauma-induced-coagulopathy-unveiling-methodological-nuances-and-treatment-variances
#18
LETTER
Bruno Caldeira Antônio, Maiara Sulzbach Denardin, Henrique Alexsander Ferreira Neves, Eduardo Messias Hirano Padrao
No abstract text is available yet for this article.
November 21, 2023: Critical Care: the Official Journal of the Critical Care Forum
https://read.qxmd.com/read/37990276/myocardial-dysfunction-assessed-by-speckle-tracking-in-good-grade-subarachnoid-hemorrhage-patients-wfns-1-2-a-prospective-observational-study
#19
JOURNAL ARTICLE
Hugues de Courson, Grégoire Chadefaux, Alexandre Loiseau, Delphine Georges, Matthieu Biais
BACKGROUND: Cardiac complications due to non-traumatic subarachnoid hemorrhage (SAH) are usually described using classical echocardiographic evaluation. Strain imaging appears to have better sensitivity than standard echocardiographic markers for the diagnosis of left ventricular dysfunction. The aim of this study was to determine the prevalence of cardiac dysfunction defined as a Global Longitudinal Strain (GLS) ≥  - 20% in patients with good-grade SAH (WFNS 1 or 2)...
November 21, 2023: Critical Care: the Official Journal of the Critical Care Forum
https://read.qxmd.com/read/37986121/in-response-to-multimodal-neuromonitoring-in-traumatic-brain-injury-patients-the-search-for-the-holy-grail
#20
LETTER
Teodor Svedung Wettervik, Erta Beqiri, Peter Smielewski
No abstract text is available yet for this article.
November 20, 2023: Critical Care: the Official Journal of the Critical Care Forum
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