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Journals Critical Care : the Official J...

Critical Care : the Official Journal of the Critical Care Forum

https://read.qxmd.com/read/36726124/assessing-oral-comprehension-with-an-eye-tracking-based-innovative-device-in-critically-ill-patients-and-healthy-volunteers-a-cohort-study-authors-response
#1
LETTER
Hélène Messet-Charrière, Stephan Ehrmann, Laetitia Bodet-Contentin
No abstract text is available yet for this article.
February 1, 2023: Critical Care: the Official Journal of the Critical Care Forum
https://read.qxmd.com/read/36707883/toward-nutrition-improving-outcome-of-critically-ill-patients-how-to-interpret-recent-feeding-rcts
#2
REVIEW
Jan Gunst, Michael P Casaer, Jean-Charles Preiser, Jean Reignier, Greet Van den Berghe
Although numerous observational studies associated underfeeding with poor outcome, recent randomized controlled trials (RCTs) have shown that early full nutritional support does not benefit critically ill patients and may induce dose-dependent harm. Some researchers have suggested that the absence of benefit in RCTs may be attributed to overrepresentation of patients deemed at low nutritional risk, or to a too low amino acid versus non-protein energy dose in the nutritional formula. However, these hypotheses have not been confirmed by strong evidence...
January 27, 2023: Critical Care: the Official Journal of the Critical Care Forum
https://read.qxmd.com/read/36707841/impact-of-continuous-hypertonic-nacl-20-saline-solution-on-renal-outcomes-after-traumatic-brain-injury-tbi-a-post-hoc-analysis-of-the-cobi-trial
#3
JOURNAL ARTICLE
Olivier Huet, Xavier Chapalain, Véronique Vermeersch, Jean-Denis Moyer, Sigismond Lasocki, Benjamin Cohen, Claire Dahyot-Fizelier, Kevin Chalard, P Seguin, Y Hourmant, Karim Asehnoune, Antoine Roquilly
BACKGROUND: To evaluate if the increase in chloride intake during a continuous infusion of 20% hypertonic saline solution (HSS) is associated with an increase in the incidence of acute kidney injury (AKI) compared to standard of care in traumatic brain injury patients. METHODS: In this post hoc analysis of the COBI trial, 370 patients admitted for a moderate-to-severe TBI in the 9 participating ICUs were enrolled. The intervention consisted in a continuous infusion of HSS to maintain a blood sodium level between 150 and 155 mmol/L for at least 48 h...
January 27, 2023: Critical Care: the Official Journal of the Critical Care Forum
https://read.qxmd.com/read/36698191/image-augmentation-and-automated-measurement-of-endotracheal-tube-to-carina-distance-on-chest-radiographs-in-intensive-care-unit-using-a-deep-learning-model-with-external-validation
#4
JOURNAL ARTICLE
Matthieu Oliver, Amélie Renou, Nicolas Allou, Lucas Moscatelli, Cyril Ferdynus, Jerôme Allyn
BACKGROUND: Chest radiographs are routinely performed in intensive care unit (ICU) to confirm the correct position of an endotracheal tube (ETT) relative to the carina. However, their interpretation is often challenging and requires substantial time and expertise. The aim of this study was to propose an externally validated deep learning model with uncertainty quantification and image segmentation for the automated assessment of ETT placement on ICU chest radiographs. METHODS: The CarinaNet model was constructed by applying transfer learning to the RetinaNet model using an internal dataset of ICU chest radiographs...
January 25, 2023: Critical Care: the Official Journal of the Critical Care Forum
https://read.qxmd.com/read/36698155/the-difference-in-the-association-between-included-ecpr-patients-and-neurological-outcomes
#5
LETTER
Toru Hifumi, Akihiko Inoue, Norio Otani
No abstract text is available yet for this article.
January 25, 2023: Critical Care: the Official Journal of the Critical Care Forum
https://read.qxmd.com/read/36698153/trough-concentration-may-not-be-a-good-target-for-polymyxin-b-therapeutic-drug-monitoring
#6
LETTER
Yuhua Zhao, Huadong Chen, Zhenwei Yu
No abstract text is available yet for this article.
January 25, 2023: Critical Care: the Official Journal of the Critical Care Forum
https://read.qxmd.com/read/36694238/pattern-of-disease-and-determinants-of-mortality-among-icu-patients-on-mechanical-ventilator-in-sub-saharan-africa-a-multilevel-analysis
#7
JOURNAL ARTICLE
Semagn Mekonnen Abate, Bivash Basu, Bedru Jemal, Siraj Ahmed, Bahru Mantefardo, Tagesse Taye
BACKGROUND: The global mortality rate of patients with MV is very high, despite a significant variation worldwide. Previous studies conducted in Sub-Saharan Africa among ICU patients focused on the pattern of admission and the incidence of mortality. However, the body of evidence on the clinical outcomes among patients with MV is still uncertain. OBJECTIVE: The objective of this study was to investigate the pattern of disease and determinants of mortality among patients receiving mechanical ventilation in Southern Ethiopia...
January 24, 2023: Critical Care: the Official Journal of the Critical Care Forum
https://read.qxmd.com/read/36694214/p-sili-in-critically-ill-covid-19-patients-macklin-effect-and-the-choice-of-noninvasive-ventilatory-support-type
#8
LETTER
Alessandro Belletti, Luigi Vetrugno, Cristian Deana, Diego Palumbo, Salvatore M Maggiore, Giovanni Landoni
No abstract text is available yet for this article.
January 24, 2023: Critical Care: the Official Journal of the Critical Care Forum
https://read.qxmd.com/read/36691082/cytokine-hemoadsorption-with-cytosorb-%C3%A2-in-post-cardiac-arrest-syndrome-a-pilot-randomized-controlled-trial
#9
RANDOMIZED CONTROLLED TRIAL
Céline Monard, Nathan Bianchi, Elettra Poli, Marco Altarelli, Anne Debonneville, Mauro Oddo, Lucas Liaudet, Antoine Schneider
BACKGROUND: Hemoadsorption (HA) might mitigate the systemic inflammatory response associated with post-cardiac arrest syndrome (PCAS) and improve outcomes. Here, we investigated the feasibility, safety and efficacy of HA with CytoSorb® in cardiac arrest (CA) survivors at risk of PCAS. METHODS: In this pilot randomized controlled trial, we included patients admitted to our intensive care unit following CA and likely to develop PCAS: required norepinephrine (> 0...
January 23, 2023: Critical Care: the Official Journal of the Critical Care Forum
https://read.qxmd.com/read/36691080/covid-19-bacteremic-co-infection-is-a-major-risk-factor-for-mortality-icu-admission-and-mechanical-ventilation
#10
MULTICENTER STUDY
Michael John Patton, Carlos J Orihuela, Kevin S Harrod, Mohammad A N Bhuiyan, Paari Dominic, Christopher G Kevil, Daniel Fort, Vincent X Liu, Maha Farhat, Jonathan L Koff, Charitharth V Lal, Anuj Gaggar, Robert P Richter, Nathaniel Erdmann, Matthew Might, Amit Gaggar
BACKGROUND: Recent single-center reports have suggested that community-acquired bacteremic co-infection in the context of Coronavirus disease 2019 (COVID-19) may be an important driver of mortality; however, these reports have not been validated with a multicenter, demographically diverse, cohort study with data spanning the pandemic. METHODS: In this multicenter, retrospective cohort study, inpatient encounters were assessed for COVID-19 with community-acquired bacteremic co-infection using 48-h post-admission blood cultures and grouped by: (1) confirmed co-infection [recovery of bacterial pathogen], (2) suspected co-infection [negative culture with ≥ 2 antimicrobials administered], and (3) no evidence of co-infection [no culture]...
January 23, 2023: Critical Care: the Official Journal of the Critical Care Forum
https://read.qxmd.com/read/36691075/temperature-control-in-adults-after-cardiac-arrest-a-survey-of-current-clinical-practice-in-germany
#11
JOURNAL ARTICLE
Kevin Roedl, Sebastian Wolfrum, Guido Michels, Martin Pin, Gerold Söffker, Uwe Janssens, Stefan Kluge
BACKGROUND: Temperature control is recommended after out of hospital cardiac arrest (OHCA) by international guidelines. This survey aimed to investigate current clinical practice and areas of uncertainty. METHODS: Online survey targeting members of three medical emergency and critical care societies in Germany (April 21-June 6, 2022) assessing post-cardiac arrest temperature control management. RESULTS: Of 341 completed questionnaires 28% (n = 97) used temperature control with normothermic target and 72% (n = 244) temperature control with hypothermic target...
January 23, 2023: Critical Care: the Official Journal of the Critical Care Forum
https://read.qxmd.com/read/36681838/clinician-perceptions-of-the-impact-of-icu-family-visiting-restrictions-during-the-covid-19-pandemic-an-international-investigation
#12
JOURNAL ARTICLE
Joanne McPeake, Nancy Kentish-Barnes, Emilie Banse, Lynne Anderson, Cecilia Cuzco, Elie Azoulay, Tara Quasim, Pedro Castro, Kathryn Puxty
PURPOSE: To guarantee the safety of the public, clinicians and patients during the COVID-19 pandemic, hospital visits were severely restricted internationally. There are limited data on the precise impact of these visiting restrictions on Intensive Care Unit clinicians. Our objectives therefore were to explore the impact of family visitation restrictions on clinicians and care delivery and describe innovation alongside areas for potential improvement. METHODS: A qualitative approach using focus groups was employed...
January 21, 2023: Critical Care: the Official Journal of the Critical Care Forum
https://read.qxmd.com/read/36670506/global-critical-care-a-call-to-action
#13
REVIEW
Ana Maria Crawford, Ananya Abate Shiferaw, Papytcho Ntambwe, Alexei Ortiz Milan, Karima Khalid, Rodrigo Rubio, Francoise Nizeyimana, Fredy Ariza, Alhassan Datti Mohammed, Tim Baker, Paulin Ruhato Banguti, Farai Madzimbamuto
Critical care is underprioritized. A global call to action is needed to increase equitable access to care and the quality of care provided to critically ill patients. Current challenges to effective critical care in resource-constrained settings are many. Estimates of the burden of critical illness are extrapolated from common etiologies, but the true burden remains ill-defined. Measuring the burden of critical illness is epidemiologically challenging but is thought to be increasing. Resources, infrastructure, and training are inadequate...
January 20, 2023: Critical Care: the Official Journal of the Critical Care Forum
https://read.qxmd.com/read/36670460/letter-to-the-editor-regarding-effect-of-icu-quality-control-indicators-on-vap-incidence-rate-and-mortality-a-retrospective-study-of-1267-hospitals-in-china
#14
LETTER
Mingqiang Wang, Lingtong Huang, Xiaohan Huang
No abstract text is available yet for this article.
January 20, 2023: Critical Care: the Official Journal of the Critical Care Forum
https://read.qxmd.com/read/36670450/prognostic-models-for-outcome-prediction-following-in-hospital-cardiac-arrest-using-pre-arrest-factors-a-systematic-review-meta-analysis-and-critical-appraisal
#15
JOURNAL ARTICLE
Casey Grandbois van Ravenhorst, Marc Schluep, Henrik Endeman, Robert-Jan Stolker, Sanne Elisabeth Hoeks
BACKGROUND: Several prediction models of survival after in-hospital cardiac arrest (IHCA) have been published, but no overview of model performance and external validation exists. We performed a systematic review of the available prognostic models for outcome prediction of attempted resuscitation for IHCA using pre-arrest factors to enhance clinical decision-making through improved outcome prediction. METHODS: This systematic review followed the CHARMS and PRISMA guidelines...
January 20, 2023: Critical Care: the Official Journal of the Critical Care Forum
https://read.qxmd.com/read/36670442/the-safety-and-efficacy-of-mesenchymal-stromal-cells-in-ards-a-meta-analysis-of-randomized-controlled-trials
#16
REVIEW
Fengyun Wang, Yiming Li, Bingqing Wang, Jianguo Li, Zhiyong Peng
Mesenchymal stromal cells (MSC) have shown potential efficacy in both animal and human trials of acute respiratory distress syndrome (ARDS). Especially during the COVID-19 pandemic, MSC was intensely studied for treating COVID-19-induced ARDS. The purpose of this study is to evaluate the safety and efficacy of MSC in ARDS via a meta-analysis of randomized controlled trials (RCTs). Therefore, a meta-analysis of RCTs of MSC as a therapy for ARDS was conducted. The protocol of this review was registered on Open Science Framework...
January 20, 2023: Critical Care: the Official Journal of the Critical Care Forum
https://read.qxmd.com/read/36670410/an-updated-norepinephrine-equivalent-score-in-intensive-care-as-a-marker-of-shock-severity
#17
REVIEW
Yuki Kotani, Annamaria Di Gioia, Giovanni Landoni, Alessandro Belletti, Ashish K Khanna
Vasopressors and fluids are the cornerstones for the treatment of shock. The current international guidelines on shock recommend norepinephrine as the first-line vasopressor and vasopressin as the second-line vasopressor. In clinical practice, due to drug availability, local practice variations, special settings, and ongoing research, several alternative vasoconstrictors and adjuncts are used in the absence of precise equivalent doses. Norepinephrine equivalence (NEE) is frequently used in clinical trials to overcome this heterogeneity and describe vasopressor support in a standardized manner...
January 20, 2023: Critical Care: the Official Journal of the Critical Care Forum
https://read.qxmd.com/read/36653857/the-cephalic-vein-catheterization-maybe-yes-but-when-there-is-no-alternative
#18
LETTER
Ryszard Gawda, Tomasz Czarnik
No abstract text is available yet for this article.
January 18, 2023: Critical Care: the Official Journal of the Critical Care Forum
https://read.qxmd.com/read/36650593/electric-impedance-tomography-guided-peep-titration-reduces-mechanical-power-in-ards-a-randomized-crossover-pilot-trial
#19
RANDOMIZED CONTROLLED TRIAL
Jose Victor Jimenez, Elizabeth Munroe, Andrew J Weirauch, Kelly Fiorino, Christopher A Culter, Kristine Nelson, Wassim W Labaki, Philip J Choi, Ivan Co, Theodore J Standiford, Hallie C Prescott, Robert C Hyzy
BACKGROUND: In patients with acute respiratory distress syndrome undergoing mechanical ventilation, positive end-expiratory pressure (PEEP) can lead to recruitment or overdistension. Current strategies utilized for PEEP titration do not permit the distinction. Electric impedance tomography (EIT) detects and quantifies the presence of both collapse and overdistension. We investigated whether using EIT-guided PEEP titration leads to decreased mechanical power compared to high-PEEP/FiO2 tables...
January 17, 2023: Critical Care: the Official Journal of the Critical Care Forum
https://read.qxmd.com/read/36650568/effect-of-apneic-oxygenation-with-intubation-to-reduce-severe-desaturation-and-adverse-tracheal-intubation-associated-events-in-critically-ill-children
#20
JOURNAL ARTICLE
Natalie Napolitano, Lee Polikoff, Lauren Edwards, Keiko M Tarquinio, Sholeen Nett, Conrad Krawiec, Aileen Kirby, Nina Salfity, David Tellez, Gordon Krahn, Ryan Breuer, Simon J Parsons, Christopher Page-Goertz, Justine Shults, Vinay Nadkarni, Akira Nishisaki
BACKGROUND: Determine if apneic oxygenation (AO) delivered via nasal cannula during the apneic phase of tracheal intubation (TI), reduces adverse TI-associated events (TIAEs) in children. METHODS: AO was implemented across 14 pediatric intensive care units as a quality improvement intervention during 2016-2020. Implementation consisted of an intubation safety checklist, leadership endorsement, local champion, and data feedback to frontline clinicians. Standardized oxygen flow via nasal cannula for AO was as follows: 5 L/min for infants (< 1 year), 10 L/min for young children (1-7 years), and 15 L/min for older children (≥ 8 years)...
January 17, 2023: Critical Care: the Official Journal of the Critical Care Forum
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