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Critical Care: the Official Journal of the Critical Care Forum

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https://read.qxmd.com/read/30764857/predicting-clinical-outcome-in-patients-undergoing-va-ecmo
#1
EDITORIAL
Antoine Kimmoun, Bruno Levy
No abstract text is available yet for this article.
February 14, 2019: Critical Care: the Official Journal of the Critical Care Forum
https://read.qxmd.com/read/30764856/nephrocheck-should-we-consider-urine-osmolality
#2
LETTER
Alberto Noto, Andrea Cortegiani, Antonio David
No abstract text is available yet for this article.
February 14, 2019: Critical Care: the Official Journal of the Critical Care Forum
https://read.qxmd.com/read/30764854/assessment-of-intestinal-perfusion-by-a-new-balloon-tipped-transpyloric-probe
#3
LETTER
Samir G Sakka
No abstract text is available yet for this article.
February 14, 2019: Critical Care: the Official Journal of the Critical Care Forum
https://read.qxmd.com/read/30760310/current-place-of-probiotics-for-vap
#4
EDITORIAL
Harjeet Singh Virk, W Joost Wiersinga
No abstract text is available yet for this article.
February 13, 2019: Critical Care: the Official Journal of the Critical Care Forum
https://read.qxmd.com/read/30760295/cerebral-metabolism-is-not-affected-by-moderate-hyperventilation-in-patients-with-traumatic-brain-injury
#5
Giovanna Brandi, Nino Stocchetti, Alberto Pagnamenta, Federica Stretti, Peter Steiger, Stephanie Klinzing
BACKGROUND: Hyperventilation-induced hypocapnia (HV) reduces elevated intracranial pressure (ICP), a dangerous and potentially fatal complication of traumatic brain injury (TBI). HV decreases the arteriolar diameter of intracranial vessels, raising the risk of cerebral ischemia. The aim of this study was to characterize the effects of moderate short-term HV in patients with severe TBI by using concomitant monitoring of cerebral metabolism, brain tissue oxygen tension (PbrO2 ), and cerebral hemodynamics with transcranial color-coded duplex sonography (TCCD)...
February 13, 2019: Critical Care: the Official Journal of the Critical Care Forum
https://read.qxmd.com/read/30760290/exosomes-from-endothelial-progenitor-cells-improve-outcomes-of-the-lipopolysaccharide-induced-acute-lung-injury
#6
Yue Zhou, Pengfei Li, Andrew J Goodwin, James A Cook, Perry V Halushka, Eugene Chang, Basilia Zingarelli, Hongkuan Fan
BACKGROUND: The acute respiratory distress syndrome (ARDS) is characterized by disruption of the alveolar-capillary barrier resulting in accumulation of proteinaceous edema and increased inflammatory cells in the alveolar space. We previously found that endothelial progenitor cell (EPC) exosomes prevent endothelial dysfunction and lung injury in sepsis in part due to their encapsulation of miRNA-126. However, the effects of EPC exosomes in acute lung injury (ALI) remain unknown. METHODS: To determine if EPC exosomes would have beneficial effects in ALI, intratracheal administration of lipopolysaccharide (LPS) was used to induce ALI in mice...
February 13, 2019: Critical Care: the Official Journal of the Critical Care Forum
https://read.qxmd.com/read/30755248/lung-fluid-biomarkers-for-acute-respiratory-distress-syndrome-a-systematic-review-and-meta-analysis
#7
Yishan Wang, Huijuan Wang, Chunfang Zhang, Chao Zhang, Huqin Yang, Ruiyue Gao, Zhaohui Tong
BACKGROUND: With the development of new techniques to easily obtain lower respiratory tract specimens, bronchoalveolar lavage fluid and other lung fluids are gaining importance in pulmonary disease diagnosis. We aimed to review and summarize lung fluid biomarkers associated with acute respiratory distress syndrome diagnosis and mortality. METHODS: After searching PubMed, Embase, Web of Science, and the Cochrane Library for articles published prior to January 11, 2018, we performed a meta-analysis on biomarkers for acute respiratory distress syndrome diagnosis in at-risk patients and those related to disease mortality...
February 12, 2019: Critical Care: the Official Journal of the Critical Care Forum
https://read.qxmd.com/read/30744687/low-dose-atrial-natriuretic-peptide-for-prevention-or-treatment-of-acute-kidney-injury-a-systematic-review-and-meta-analysis
#8
Hiroyuki Yamada, Kent Doi, Tatsuo Tsukamoto, Hideyasu Kiyomoto, Kazuto Yamashita, Motoko Yanagita, Yoshio Terada, Kiyoshi Mori
BACKGROUND: Theoretically, atrial natriuretic peptide (ANP), especially low-dose ANP, is beneficial in acute kidney injury (AKI). In this study, we examined whether low-dose ANP is effective in preventing or treating AKI by conducting an updated systematic review for randomized controlled trials (RCTs). METHOD: We searched the Excerpta Medica database (EMBASE), PubMed, and Cochrane CENTRAL databases for RCTs that compare the effects of low-dose ANP (≤ 50 ng/kg/min) with a placebo or conventional therapy in at-risk patients or patients with AKI...
February 11, 2019: Critical Care: the Official Journal of the Critical Care Forum
https://read.qxmd.com/read/30744667/thromboxane-prostaglandin-receptor-antagonist-terutroban-prevents-neurovascular-events-after-subarachnoid-haemorrhage-a-nanospect-study-in-rats
#9
David Lagier, David Tonon, Philippe Garrigue, Benjamin Guillet, Laura Giacomino, Jean-Charles Martin, Marie-Christine Alessi, Nicolas Bruder, Lionel J Velly
BACKGROUND: Several lipid metabolites in cerebrospinal fluid are correlated with poor outcomes in aneurysmal subarachnoid haemorrhage. Most of these metabolites bind to ubiquitous thromboxane-prostaglandin (TP) receptors, causing vasoconstriction and inflammation. Here, we evaluated terutroban (TBN), a specific TP receptor antagonist, for the prevention of post-haemorrhage blood-brain barrier disruption, neuronal apoptosis and delayed cerebral hypoperfusion. METHODS: The rat double subarachnoid haemorrhage model was produced by twice injecting (days 1 and 2) autologous blood into the cisterna magna...
February 11, 2019: Critical Care: the Official Journal of the Critical Care Forum
https://read.qxmd.com/read/30736862/the-early-identification-of-disease-progression-in-patients-with-suspected-infection-presenting-to-the-emergency-department-a-multi-centre-derivation-and-validation-study
#10
Kordo Saeed, Darius Cameron Wilson, Frank Bloos, Philipp Schuetz, Yuri van der Does, Olle Melander, Pierre Hausfater, Jacopo M Legramante, Yann-Erick Claessens, Deveendra Amin, Mari Rosenqvist, Graham White, Beat Mueller, Maarten Limper, Carlota Clemente Callejo, Antonella Brandi, Marc-Alexis Macchi, Nicholas Cortes, Alexander Kutz, Peter Patka, María Cecilia Yañez, Sergio Bernardini, Nathalie Beau, Matthew Dryden, Eric C M van Gorp, Marilena Minieri, Louisa Chan, Pleunie P M Rood, Juan Gonzalez Del Castillo
BACKGROUND: There is a lack of validated tools to assess potential disease progression and hospitalisation decisions in patients presenting to the emergency department (ED) with a suspected infection. This study aimed to identify suitable blood biomarkers (MR-proADM, PCT, lactate and CRP) or clinical scores (SIRS, SOFA, qSOFA, NEWS and CRB-65) to fulfil this unmet clinical need. METHODS: An observational derivation patient cohort validated by an independent secondary analysis across nine EDs...
February 8, 2019: Critical Care: the Official Journal of the Critical Care Forum
https://read.qxmd.com/read/30736846/letter-on-left-ventricular-systolic-function-evaluated-by-strain-echocardiography-and-relationship-with-mortality-in-patients-with-severe-sepsis-or-septic-shock-a-systematic-review-and-meta-analysis
#11
LETTER
Venu M Velagapudi, Dennis A Tighe
No abstract text is available yet for this article.
February 8, 2019: Critical Care: the Official Journal of the Critical Care Forum
https://read.qxmd.com/read/30736845/the-elso-maastricht-treaty-for-ecls-nomenclature-abbreviations-for-cannulation-configuration-in-extracorporeal-life-support-a-position-paper-of-the-extracorporeal-life-support-organization
#12
Lars Mikael Broman, Fabio Silvio Taccone, Roberto Lorusso, Maximilian Valentin Malfertheiner, Federico Pappalardo, Matteo Di Nardo, Mirko Belliato, Melania M Bembea, Ryan P Barbaro, Rodrigo Diaz, Lorenzo Grazioli, Vincent Pellegrino, Malaika H Mendonca, Daniel Brodie, Eddy Fan, Robert H Bartlett, Michael M McMullan, Steven A Conrad
BACKGROUND: The Extracorporeal Life Support Organization (ELSO) Maastricht Treaty for Nomenclature in Extracorporeal Life Support (ECLS) established consensus nomenclature and abbreviations for ECLS to ensure accurate, concise communication. METHODS: We build on this consensus nomenclature by layering a framework of precise and efficient abbreviations for cannula configuration that describe flow direction, number of cannulae used, any additional ECLS-related catheters, and cannulation sites...
February 8, 2019: Critical Care: the Official Journal of the Critical Care Forum
https://read.qxmd.com/read/30736839/passive-leg-cycling-and-electrical-stimulation-cannot-preserve-strength-in-sepsis
#13
LETTER
Pierre-François Laterre, Cheryl Hickmann, Diego Castanares-Zapatero
No abstract text is available yet for this article.
February 8, 2019: Critical Care: the Official Journal of the Critical Care Forum
https://read.qxmd.com/read/30736830/impact-of-post-traumatic-stress-symptoms-on-the-health-related-quality-of-life-in-a-cohort-study-with-chronically-critically-ill-patients-and-their-partners-age-matters
#14
Gloria-Beatrice Wintermann, Katja Petrowski, Kerstin Weidner, Bernhard Strauß, Jenny Rosendahl
BACKGROUND: Survivors of an acute critical illness with continuing organ dysfunction and uncontrolled inflammatory responses are prone to become chronically critically ill. As mental sequelae, a post-traumatic stress disorder and an associated decrease in the health-related quality of life (QoL) may occur, not only in the patients but also in their partners. Currently, research on long-term mental distress in chronically critically ill patient-partner dyads, using appropriate dyadic analysis strategies (patients and partners being measured and linked on the same variables) and controlling for contextual factors, is lacking...
February 8, 2019: Critical Care: the Official Journal of the Critical Care Forum
https://read.qxmd.com/read/30736819/is-fluid-resuscitation-the-keyser-soze-of-acute-kidney-injury-in-trauma-patients
#15
LETTER
Matthieu Jamme, Omar Ben Hadj Salem
No abstract text is available yet for this article.
February 8, 2019: Critical Care: the Official Journal of the Critical Care Forum
https://read.qxmd.com/read/30696474/organizational-factors-associated-with-target-sedation-on-the-first-48-h-of-mechanical-ventilation-an-analysis-of-checklist-icu-database
#16
Antonio Paulo Nassar, Fernando G Zampieri, Jorge I Salluh, Fernando A Bozza, Flávia Ribeiro Machado, Helio Penna Guimarães, Lucas P Damiani, Alexandre Biasi Cavalcanti
BACKGROUND: Although light sedation levels are associated with several beneficial outcomes for critically ill patients on mechanical ventilation, the majority of patients are still deeply sedated. Organizational factors may play a role on adherence to light sedation levels. We aimed to identify organizational factors associated with a moderate to light sedation target on the first 48 h of mechanical ventilation, as well as the association between early achievement of within-target sedation and mortality...
January 29, 2019: Critical Care: the Official Journal of the Critical Care Forum
https://read.qxmd.com/read/30696473/electrophysiological-investigations-of-peripheral-nerves-and-muscles-a-method-for-looking-at-cell-dysfunction-in-the-critically-ill-patients
#17
EDITORIAL
Nicola Latronico, Oliver Friedrich
No abstract text is available yet for this article.
January 29, 2019: Critical Care: the Official Journal of the Critical Care Forum
https://read.qxmd.com/read/30691528/humanizing-the-intensive-care-unit
#18
EDITORIAL
Michael E Wilson, Sarah Beesley, Amanda Grow, Eileen Rubin, Ramona O Hopkins, Negin Hajizadeh, Samuel M Brown
No abstract text is available yet for this article.
January 28, 2019: Critical Care: the Official Journal of the Critical Care Forum
https://read.qxmd.com/read/30691525/the-adrenal-vitamin-c-axis-from-fish-to-guinea-pigs-and-primates
#19
LETTER
Michael H Hooper, Anitra Carr, Paul E Marik
No abstract text is available yet for this article.
January 28, 2019: Critical Care: the Official Journal of the Critical Care Forum
https://read.qxmd.com/read/30691523/sigh-maneuver-to-enhance-assessment-of-fluid-responsiveness-during-pressure-support-ventilation
#20
Antonio Messina, Davide Colombo, Federico Lorenzo Barra, Gianmaria Cammarota, Giacomo De Mattei, Federico Longhini, Stefano Romagnoli, Francesco DellaCorte, Daniel De Backer, Maurizio Cecconi, Paolo Navalesi
BACKGROUND: Assessment of fluid responsiveness is problematic in intensive care unit (ICU) patients, in particular for those undergoing modes of partial support, such as pressure support ventilation (PSV). We propose a new test, based on application of a ventilator-generated sigh, to predict fluid responsiveness in ICU patients undergoing PSV. METHODS: This was a prospective bi-centric interventional study conducted in two general ICUs. In 40 critically ill patients with a stable ventilatory PSV pattern and requiring volume expansion (VE), we assessed the variations in arterial systolic pressure (SAP), pulse pressure (PP) and stroke volume index (SVI) consequent to random application of 4-s sighs at three different inspiratory pressures...
January 28, 2019: Critical Care: the Official Journal of the Critical Care Forum
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