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International Journal of Psychiatry in Clinical Practice

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https://read.qxmd.com/read/30762438/high-rates-of-depression-anxiety-and-suicidal-ideation-among-inpatients-in-general-hospital-in-china
#1
Mingjin Huang, Yang Liu, Jian Wang, Liling Mo, Yu Wang, Liang Chen, Zaiquan Dong, Wanjun Guo, Ning He, Ran Chen, Shanxia Luo, Jianying Yu, Lan Zhang
OBJECTIVE: To investigate the prevalence rates of depression anxiety and suicidal ideation among Chinese general hospital inpatients and to identify the potential associations with sociodemographics. METHOD: A cross-sectional survey was applied in a Chinese general hospital. A questionnaire set, including sociodemographic variables, Patient Health Questionnaire-9 (PHQ-9), and the Generalized Anxiety Disorder Scale-7 (GAD-7), was completed by the participants. Clinically significant depression (CSD) and clinically significant anxiety (CSA) were defined as a score above 10 on the two scales...
February 14, 2019: International Journal of Psychiatry in Clinical Practice
https://read.qxmd.com/read/30741069/cardiovascular-events-in-hospitalised-patients-with-schizophrenia-a-survival-analysis
#2
Ghina Al-Seddik, Dory Hachem, Chadia Haddad, Souheil Hallit, Pascale Salameh, Rita Nabout, Marouan Zoghbi
OBJECTIVE: To evaluate the occurrence of cardiovascular (CV), cerebrovascular events and mortality rates, and compare the predictive ability of two scores, Framingham Risk Score (FRS) and Atherosclerotic Cardiovascular Disease (ASCVD), of detecting a cardiovascular event in a cohort of schizophrenic patients. METHODS: A cohort of 329 hospitalised schizophrenic patients is being monitored since 1 January 2013. Patients' file review was performed to detect the CV events of interest...
February 10, 2019: International Journal of Psychiatry in Clinical Practice
https://read.qxmd.com/read/30732488/switching-medication-products-during-the-treatment-of-psychiatric-illness
#3
Pierre Blier, Howard C Margolese, E Adriana Wilson, Matthieu Boucher
BACKGROUND: The common practice of switching between branded (reference) medications and their corresponding generic products, between generic products, or even from a generic product to a branded medication during the treatment of central nervous system (CNS) disorders may compromise efficacy and/or tolerability. METHODS: We assessed the published literature from March 1, 2010 through June 30, 2017 via PubMed using the MeSH term 'generics, drugs' alone and in combination with class-specific terms (e...
February 8, 2019: International Journal of Psychiatry in Clinical Practice
https://read.qxmd.com/read/30707042/choosing-among-second-generation-antidepressant-treatments-for-depressed-patients-with-cardiac-diseases
#4
Siegfried Kasper
OBJECTIVES: The present paper aimed to assist physicians in the accurate choice among second-generation agents (SGAs) for patients with cardiovascular disease (CVD). METHODS: We reviewed the published pharmacokinetic (PK) and pharmacodynamic (PD) clinical data that report potential -or absence of- drug interactions between second-generation agents (SGAs) and CVD drugs most commonly used in cardiology, including antiplatelet drugs and anticoagulants, statins, beta-blockers, angiotensin-converting enzyme inhibitors, calcium channel blockers, diuretics and the antiarrhythmic drugs amiodarone and digoxin...
February 1, 2019: International Journal of Psychiatry in Clinical Practice
https://read.qxmd.com/read/30663922/long-term-cardiovascular-safety-of-psychostimulants-in-children-with-attention-deficit-hyperactivity-disorder
#5
Annette Conzelmann, Stefan Müller, Thomas Jans, Götz-Erik Trott, Thomas Keil, Manfred Gerlach, Tobias J Renner
OBJECTIVE: Side effects are a concern during psychostimulant treatment. Unfortunately, many previous studies only investigated short-term effects of psychostimulants in laboratory settings which lack clinical daily routines. METHODS: We examined 1042 patient records of patients with attention deficit hyperactivity disorder (ADHD) who were referred to a pediatric-psychiatry practice over 12 years. Data analysis was based on 466 children with ADHD who were newly treated with psychostimulants and who were not in treatment for elevated blood pressure...
January 21, 2019: International Journal of Psychiatry in Clinical Practice
https://read.qxmd.com/read/30596528/orexin-hypocretin-receptor-orx-1-gene-variants-are-associated-with-major-depressive-disorder
#6
Mujgan Cengiz, Vilson Karaj, Nese Kocabasoğlu, Gokcen Gozubatik-Celik, Ahmet Dirican, Burcu Bayoglu
OBJECTIVE: Orexins (hypocretins) are neuropeptides expressed in hypothalamic neurons and have regulatory roles in feeding/drinking behaviours, endocrine functions and sleep/wakefulness state. Major depressive disorder (MDD) is a major mood disorder and neurotransmitter dysfunction in hypothalamic neurons may have roles in its formation. Hence, we conducted experiments to determine whether orexin receptor 1 and 2 (Orx1 , Orx2 ) genes were associated with MDD development. METHODS: Seventy-five MDD patients and 87 healthy controls were enrolled for the study...
December 31, 2018: International Journal of Psychiatry in Clinical Practice
https://read.qxmd.com/read/30596524/the-alteration-of-retinal-nerve-fibre-layer-thickness-with-repetitive-transcranial-magnetic-stimulation-in-patients-with-treatment-resistant-major-depression
#7
Abdullah Genc, Mihriban Dalkıran, Efruz Pirdoğan Aydın, Ece Türkyılmaz Uyar, Alparslan Alkan, Dilek Guven, Ömer Akil Özer, Oğuz Karamustafalıoğlu
OBJECTIVE: The nerves and axons of the retinal nerve fibre layer (RNFL) are similar to those in the brain and therefore retina is considered as the extension of the brain. We aimed to evaluate the RNFL thickness in the treatment-resistant major depressive patients before and after repetitive transcranial magnetic stimulation (rTMS) treatment and at least 6 months later after rTMS treatment using optical coherence tomography (OCT). METHODS: Thirty patients with treatment resistant major depression and 24 healthy controls were included in the study...
December 31, 2018: International Journal of Psychiatry in Clinical Practice
https://read.qxmd.com/read/30570343/problematic-internet-use-and-feelings-of-loneliness
#8
Rui Miguel Costa, Ivone Patrão, Mariana Machado
OBJECTIVES: Internet addiction or problematic internet use (PIU) has been related to feelings of loneliness and social networking. Research suggests that online communication may cause loneliness. We examined if the association between PIU and loneliness is independent of lack of social support, as indicated by lack of a committed romantic relationship, poor family functioning, and lack of time to interact face-to-face due to time online. METHODS: Portuguese adolescents and young adults (N = 548: 16-26 years) completed the Generalized Problematic Internet Use Scale-2, the UCLA Loneliness Scale, and the general functioning subscale of the McMaster Family Assessment Device...
December 20, 2018: International Journal of Psychiatry in Clinical Practice
https://read.qxmd.com/read/30261781/preventive-effect-of-cyproheptadine-on-sleep-and-appetite-disorders-induced-by-methylphenidate-an-exploratory-randomised-double-blinded-placebo-controlled-clinical-trial
#9
Faezeh Kadkhoda Mezerji, Fatemeh Moharreri, Amir Hooshang Mohammadpour, Sepideh Elyasi
OBJECTIVES: Insomnia and loss of appetite are the most common side effects of methylphenidate in patients with attention deficit/hyperactivity disorder (ADHD). The adverse effects may limit optimal dosing and patients' compliance with treatment leading to the discontinuation of treatment. This research evaluates the preventive effects of cyproheptadine on sleeping and appetite disorders induced by methylphenidate in ADHD children. METHODS: During this exploratory, randomised, double-blinded, placebo-controlled clinical trial, forty patients with ADHD diagnosis who had received methylphenidate randomly were assigned to participate in the cyproheptadine or the placebo group...
September 27, 2018: International Journal of Psychiatry in Clinical Practice
https://read.qxmd.com/read/30067153/editorial
#10
EDITORIAL
Siegfried Kasper
No abstract text is available yet for this article.
September 2018: International Journal of Psychiatry in Clinical Practice
https://read.qxmd.com/read/29421942/autonomous-motivation-and-quality-of-life-as-predictors-of-physical-activity-in-patients-with-schizophrenia
#11
Raquel Costa, Tânia Bastos, Michel Probst, André Seabra, Estela Vilhena, Rui Corredeira
AIM: Being physically active is a complex behaviour in patients with schizophrenia. Several factors were identified as barriers to achieving active behaviours in this population. Therefore, the purpose of this study was to investigate among a number of barriers what predicts the most on physical activity (PA) in patients with schizophrenia. METHODS: A total of 114 patients (28♀) with schizophrenia were included. Body mass index (BMI) was calculated. Autonomous and controlled motivation (Behavioural Regulation in Exercise Questionnaire - 3), self-esteem (Rosenberg Self-esteem scale), quality of life (World Health Organization Quality of Life Scale - Brief version) and functional exercise capacity (6-minute walk test - 6MWT) were evaluated...
September 2018: International Journal of Psychiatry in Clinical Practice
https://read.qxmd.com/read/29235398/antipsychotic-treatment-of-community-dwelling-and-institutionalised-patients-with-dementia-in-germany
#12
Philipp Hessmann, Richard Dodel, Erika Baum, Matthias J Müller, Greta Paschke, Bernhard Kis, Jan Zeidler, Mike Klora, Jens-Peter Reese, Monika Balzer-Geldsetzer
OBJECTIVE: A restrictive use of antipsychotic drugs in patients with Alzheimer's disease (AD) is recommended due to an increased risk of cerebrovascular events and mortality. We hypothesise that the prescription of antipsychotics is associated with the patients' socio-demographic and clinical status (e.g., dementia severity). METHODS: The prescription of antipsychotics was cross-sectionally evaluated in 272 community-dwelling and 123 institutionalised patients with AD across all severity stages of dementia...
September 2018: International Journal of Psychiatry in Clinical Practice
https://read.qxmd.com/read/29216784/evaluation-of-peripheral-serotonin-content-and-%C3%AE-2-adrenergic-receptor-function-as-potential-markers-for-life-long-recurrent-depressive-disorder-by-using-methodological-improvements
#13
Boris Aleksovski, Antoni Novotni, Viktorija Vujović, Vladimir Rendevski, Nensi Manusheva, Violeta Neceva, Ana Filipce, Aleksandar Risteski, Vasko Aleksovski, Icko Gjorgoski
OBJECTIVE: We aimed to evaluate the role and the relations between peripheral platelet serotonin content, blood plasma serotonin concentration and the function of platelet α2 -adrenergic receptors (α2 -AR) as potential state or trait biomarkers for recurrent depressive disorder (RDD). METHODS: 26 drug-free patients with life-long RDD and 31 healthy controls were included in the study. Several methodological improvements in blood collection and platelet isolation were implemented following the present standards in Haematology and Light transmission aggregometry...
September 2018: International Journal of Psychiatry in Clinical Practice
https://read.qxmd.com/read/29179627/delirium-is-associated-with-increased-mortality-in-the-geriatric-population
#14
Pinar Tosun Tasar, Sevnaz Sahın, Nur Ozge Akcam, Cıgdem Dınckal, Merve Gulsah Ulusoy, Ozan Fatih Sarıkaya, Soner Duman, Fehmi Akcıcek, Aysin Noyan
OBJECTIVE: The aim of this study was to investigate the prevalence of delirium and its association with mortality rates in elderly inpatients. METHODS: The medical records of 1435 patients over 65 years old who were treated at a regional university hospital and were referred to the university's Consultation and Liaison Psychiatry Clinic for psychological evaluation were retrospectively analyzed. Patients with and without a diagnosis of delirium were compared. The National Survival Database was used to determine mortality rates...
September 2018: International Journal of Psychiatry in Clinical Practice
https://read.qxmd.com/read/29172802/the-effect-of-antidepressant-medications-in-the-management-of-heart-failure-on-outcomes-mortality-cardiovascular-function-and-depression-a-systematic-review
#15
REVIEW
Thurkka Rajeswaran, Carla M Plymen, Anne M Doherty
OBJECTIVE: Depression is associated with increased morbidity, mortality and hospital readmission in patients with heart failure (HF). This systematic review aimed to compile studies examining whether the use of antidepressants could improve outcome in patients with HF and concomitant depression. METHODS: The electronic libraries Embase, OVID MEDLINE(R) and PsychInfo were used to search the following terms 'heart failure' AND 'anti-depressants'; 'heart failure' AND 'TCA' OR 'SSRI' OR 'SNRI'...
September 2018: International Journal of Psychiatry in Clinical Practice
https://read.qxmd.com/read/29161951/an-open-treatment-six-week-study-of-the-clinical-effectiveness-of-paliperidone-palmitate-in-schizophrenia-data-from-acute-units-in-spain-shadow-study
#16
MULTICENTER STUDY
Eduard Parellada, Miquel Bioque, Manuel Serrano, Berta Herrera, Marta García Dorado
OBJECTIVES: To evaluate clinical evolution of patients with schizophrenia admitted in acute units because of a relapse and treated with once-monthly Paliperidone Palmitate (PP1M). METHODS: This multicentre, open-label, prospective observational study followed patients with schizophrenia treated with PP1M in acute psychiatric units for up to 6 weeks. RESULTS: Out of the 280 enrolled patients, 61 received PP1M as antipsychotic monotherapy, and 219 in combination with other antipsychotics...
September 2018: International Journal of Psychiatry in Clinical Practice
https://read.qxmd.com/read/29160131/the-views-of-early-intervention-service-staff-on-the-treatment-of-first-episode-bipolar-disorder
#17
Steven Marwaha, Thomas Beirne, Matthew Broome, Rachel Upthegrove, Tobias Rowland, Andrew Thompson
OBJECTIVE: Little is known about how first episode bipolar disorder (BD) is managed in early intervention for psychosis services (EIS). We aimed to investigate the knowledge and views of EIS staff on the assessment and treatment of BD. METHODS: A 27-item anonymised online questionnaire was distributed to EIS mental health professionals in England. Descriptive data analysis was undertaken. RESULTS: Responses were received from 117 EIS staff...
September 2018: International Journal of Psychiatry in Clinical Practice
https://read.qxmd.com/read/29082784/genderwise-clinical-response-of-antipsychotics-among-schizophrenic-patients-a-prospective-observational-study-from-lahore-pakistan
#18
Usama Asif, Zikria Saleem, Mahrukh Yousaf, Hamid Saeed, Furqan Khurshid Hashmi, Muhammad Islam, Mohamed Azmi Hassali, Fahad Saleem
OBJECTIVE: The study was aimed to evaluate the gender specific response to adherence and occurrence of side effects among schizophrenic patients in Lahore, Pakistan. METHODS: A prospective study was performed for a period of 1 year among 180 newly diagnosed schizophrenics, aged 20-60 years to observe the symptoms, medication adherence and side effects. Morisky-Green-Levine Scale was used to evaluate medication adherence, LUNSER for side effects and PANSS to measure positive and negative symptoms...
September 2018: International Journal of Psychiatry in Clinical Practice
https://read.qxmd.com/read/29069974/body-dysmorphic-disorder-and-its-associated-psychological-and-psychopathological-features-in-an-italian-community-sample
#19
Silvia Cerea, Gioia Bottesi, Jessica R Grisham, Marta Ghisi
OBJECTIVE: Body Dysmorphic Disorder (BDD) is a psychiatric condition characterized by preoccupation with perceived defects in physical appearance that are not observable or appear slight to others, along with low self-esteem, high perfectionism, and high comorbidity. Little is known about BDD prevalence and phenomenology in the Italian context, and no data are currently available on BDD prevalence using DSM-5 criteria in the Italian context. The aims of the current study were to explore the prevalence and the phenomenology of BDD and its associated psychological and psychopathological features such as self-esteem, perfectionistic traits, social anxiety, depressive, and obsessive-compulsive symptoms in a community sample...
September 2018: International Journal of Psychiatry in Clinical Practice
https://read.qxmd.com/read/29069946/paternal-and-maternal-age-as-risk-factors-for-schizophrenia-a-case-control-study
#20
Konstantinos N Fountoulakis, Xenia Gonda, Melina Siamouli, Panagiotis Panagiotidis, Katerina Moutou, Ioannis Nimatoudis, Siegfried Kasper
OBJECTIVE: Advanced parental age might constitute a generic risk factor for mental and somatic disorders. The current study tested whether this concerns also patients with schizophrenia. METHODS: A total of 231 schizophrenic, 56 other severe mental disorders patients and 204 controls were diagnosed according to DSM-IV-TR. Data were tested with ANOVA models including relative risk and odds ratios. RESULTS: Patients with schizophrenia manifested higher paternal (32...
September 2018: International Journal of Psychiatry in Clinical Practice
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