Journals Clinical Hemorheology and Micr...

Clinical Hemorheology and Microcirculation
Zehong Wu, Manli Liao, Huajuan Li, Shengchao Huang, Xin Liang, Bohan Chen, Guoli Zhang, Yuping Yang, Xiaohong Xu
 Secretory carcinoma of the breast (SCB) is a rare and specific type of breast cancer. Owing to its rarity, the number of SCB reports available is limited, with most of them focusing on clinical and pathological characteristics but no reports on its multimodal ultrasound (US) features. Thus, we present a rare case of SCB, retrospectively analyzing manifestations of US and contrast-enhanced US, as well as its pathological basis, aiming to enhance the understanding of US image features of SCB and provide more valuable information for clinical diagnosis...
February 20, 2024: Clinical Hemorheology and Microcirculation
Masataka Inoue, Masahiro Ohwada, Nobuo Watanabe
BACKGROUND: Several conventional studies focused on platelet pinocytosis for possible utilization as drug delivery systems. Although platelet pinocytosis is important in such utilization, the impact of the shear rate on pinocytosis is unclear. OBJECTIVE: Our objective was to investigate the relationship between shear rate and platelet pinocytosis in vitro. In addition, this study addressed the change in platelet aggregation reactivity with adenosine diphosphate (ADP) stimulation after pinocytosis...
February 20, 2024: Clinical Hemorheology and Microcirculation
Ying Wang, Xiao-Fan Tian, Juan Cheng, Xin-Liang Xu, Jia-Ying Cao, Yi Dong, Christoph F Dietrich
OBJECTIVE: To evaluate pancreatic tissue stiffness and provide a normal reference shear wave velocity (SWV) value of pancreas from healthy adults by Virtual Touch Imaging Quantification (VTIQ) measurements. METHODS: Healthy adult volunteers without known history of hepatobiliary or pancreatic diseases were included. VTIQ elastography (Siemens ACUSON Sequoia, 5C-1 transducer) was used. SWV values were measured at the cephalic, corpus and tail of pancreas and replicated different operators' obtained data...
February 19, 2024: Clinical Hemorheology and Microcirculation
Shengqiao Wang, Xinliang Xu, Siqi Cao, Juan Cheng, Ying Wang, Yi Dong
BACKGROUND: Type 2 diabetes accelerates the loss of muscle mass and strength. Sarcopenia is also one of the chronic complications of diabetes. OBJECTIVE: To investigate the clinical value of B mode ultrasound (BMUS) and shear wave elastography (SWE) for predicting type 2 diabetic sarcopenia. METHODS: We recorded Skeletal Muscle Mass Index (ASMI), grip strength, muscle thickness (MT), pinna angle (PA), fascicle length (FL), and the difference of Young's modulus in the relaxed states and tense states (ΔSWE)...
February 16, 2024: Clinical Hemorheology and Microcirculation
F Jung
No abstract text is available yet for this article.
February 16, 2024: Clinical Hemorheology and Microcirculation
M Mantskava, L Chkhitauri, E Shekiladze, N Tskhvediani, S Kalmakhelidze, N Momtselidze, L Prantl, F Jung, B Machalinski, P Wojciech, T Sanikidze
BACKGROUND: The triad "insulin resistance, prediabetes, diabetes" is three independent neologies with characteristic features and development. In addition, each are characterized by progression and the possibility of transition from one form to other. Due to the fact that diabetes is one of the common diseases associated with high rates of disability, it is necessary to improve diagnostic methods and educational regimens for successful prevention and treatment of the disease. OBJECTIVE: We investigated Band 3 protein (B3p) level, osmotic resistance of erythrocytes, the total antioxidant activity (TAA) of blood serum, level of HbA1 in group patients with insulin resistance (IR), prediabetes, and Type 2 Diabetes Mellitus (T2DM) and comparative with health control group...
February 15, 2024: Clinical Hemorheology and Microcirculation
Yi-Ming Zhang, Guo-Hua Wang, Miao-Jun Xu, Gan Jin
OBJECTIVE: This study was designed to investigate the role of 8-oxoguanine DNA glycosylase 1 (OGG1) in preventing atherosclerosis-induced vascular EC injury, thereby providing a theoretical basis for the exploration of drug targets and treatment methods for atherosclerosis. METHODS: Human umbilical vein cell line (EA.hy926) was treated with ox-LDL to construct an in vitro atherosclerotic cell model. pcDNA3.1-OGG1 was transfected into EA.hy926 cells to overexpress OGG1...
February 14, 2024: Clinical Hemorheology and Microcirculation
Konstantinos Tzirakis, Nikolaos Kontopodis, Christos V Ioannou
PURPOSE: To compare the hemodynamic performance of three (Bottom Up non-ballet, Top-Down non-ballet, Top Down ballet) idealized stent graft configurations used during endovascular repair of abdominal aortic aneurysms, under the influence of various rheological models. METHODS: Ten rheological models are assumed and a commercial finite volume solver is employed for the simulation of blood flow under realistic boundary conditions. An appropriate mesh convergence study is performed and five hemodynamic variables are computed: the time average wall shear stress (TAWSS), oscillatory shear index (OSI), relative residence time (RRT), endothelial cell activation potential and displacement force (DF) for all three configurations...
February 13, 2024: Clinical Hemorheology and Microcirculation
Thomas Betz, Karin Pfister, Wilma Schierling, Georgios Sachsamanis, Jörn Radunski, Claus Nolte Ernsting, Alexander Stehr
BACKGROUND: The popliteal artery is highly exposed to biomechanical stress, which is the primary factor associated with stent failure. However, information on the optimal endovascular treatment for the popliteal artery is lacking. OBJECTIVE: To report the efficacy of the GORE® TIGRIS® Vascular Stent for the endovascular treatment of popliteal artery lesions. METHODS: Retrospective analysis of all patients with symptoms of peripheral artery occlusive disease (PAD) and popliteal artery lesions who underwent implantation of a GORE® TIGRIS® Vascular Stent between August 2012 and August 2014 at a tertiary vascular centre...
February 8, 2024: Clinical Hemorheology and Microcirculation
Keke Chen, Feihang Wang, Minying Deng, Kai Yuan, Xi Wang, Qiannan Zhao, Yi Dong, Wenping Wang
BACKGROUND: Hepatic reactive lymphoid hyperplasia (RLH) is a rare benign lymphoproliferative lesion and a poorly understood disease. It is usually asymptomatic and incidental, but it is difficult to distinguish from hepatocellular carcinoma and metastatic liver tumor on imaging, and percutaneous biopsy is not sufficient to distinguish from low-grade malignant lymphoma and extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma), making diagnosis difficult...
February 7, 2024: Clinical Hemorheology and Microcirculation
Qiubing Zhang, Fang Gou, Ping Shi, Zhe Xu, Zhitao Yan, Mingfang He, Xiaohong Yin, Yuanjun He, Jun Zhang
BACKGROUND: Angiotensin-converting enzyme inhibitors (ACEIs) were reported to protect from hypoxia-induced oxidative stress in coronary endothelial cells (CECs) after acute myocardial infarction (AMI). Nrf2 shows a protective effect in hypoxia-induced CECs after AMI. Plasmalemma vesicle-associated protein (PLVAP) plays a pivotal role in angiogenesis after AMI. AIM: To explore the protective effect of ACEIs and the involved mechanisms under hypoxia challenge. METHODS: Human coronary endothelial cells (HCAECs) were used to establish hypoxia-induced oxidative stress injury in vitro...
February 7, 2024: Clinical Hemorheology and Microcirculation
Simone Hammer, Danilo Weber Nunes, Michael Hammer, Florian Zeman, Michael Akers, Andrea Götz, Annika Balla, Michael Christian Doppler, Claudia Fellner, Natascha Platz Batista da Silva, Sylvia Thurn, Niklas Verloh, Christian Stroszczynski, Walter Alexander Wohlgemuth, Christoph Palm, Wibke Uller
BACKGROUND: Differentiation of high-flow from low-flow vascular malformations (VMs) is crucial for therapeutic management of this orphan disease. OBJECTIVE: A convolutional neural network (CNN) was evaluated for differentiation of peripheral vascular malformations (VMs) on T2-weighted short tau inversion recovery (STIR) MRI. METHODS: 527 MRIs (386 low-flow and 141 high-flow VMs) were randomly divided into training, validation and test set for this single-center study...
February 1, 2024: Clinical Hemorheology and Microcirculation
Negin Kordi, Ali Saydi, Sajad Karami, Behnam Bagherzadeh-Rahmani, Emanuele Marzetti, Friedrich Jung, Brent R Stockwell
 Ferroptosis is a form of programmed cell death that plays a significant role in causing several diseases such as heart attack and heart failure, through alterations in fat, amino acid, and iron metabolism. Comprehending the regulatory mechanisms of ferroptosis signaling is critical because it has a considerable effect on the elderly's mortality. Conversely, age-related changes in substrate metabolism and metabolite levels are recognized to give rise to obesity. Furthermore, research has proposed that aging and obesity-related changes in substrate metabolism may aggravate ferroptosis...
January 30, 2024: Clinical Hemorheology and Microcirculation
Xingping Men, Aizhen Hu, Tingting Xu
Atherosclerosis (AS) is a major chronic non-communicable disease and a primary cause of cardiovascular disease. Recent studies have shown that circRNAs are potential epigenetic factors that regulate vascular endothelial inflammatory responses and AS progression. Therefore, identification of the circRNAs that regulate ox-LDL levels is a critical step to understanding the pathology of AS. Our study is aim to investigate how circLZIC regulates atherosclerosis (AS) via the Micro-330-5p/NOTCH2 regulatory axis. The results showed that CircLZIC and NOTCH2 are highly expressed in human AS clinical samples, while Micro-330-5p is expressed locally...
January 25, 2024: Clinical Hemorheology and Microcirculation
Yanghong Pan, Delin Liu, Fei Liang, Zixiang Kong, Xu Zhang, Qinqin Ai
BACKGROUND: No studies have been retrieved comparing perfluorobutane with sulfur hexafluoride for microwave ablation (MWA) in small hepatocellular carcinoma(sHCC). OBJECTIVE: To retrospective investigate the value of perfluorobutane ultrasonography contrast agent in ultrasonography (US)-guided MWA of sHCC. METHODS: We conducted a retrospective clinical controlled study about US-guided percutaneous MWA in patients with sHCC, and in patients undergoing intra-operative treatment with perfluorobutane or sulfur hexafluoride...
January 24, 2024: Clinical Hemorheology and Microcirculation
Yasemin Yildiz, Emre Mutlu, Okan Arihan, A Elif Anil Yagcioglu, Neslihan H Dikmenoglu Falkmarken
BACKGROUND: Hemorheological parameters have been reported to be altered in cardiovascular disease. Major depression has been associated with increased risk of cardiovascular disease. OBJECTIVE: Our hypothesis is that hemorheological parameters are disturbed in major depressive disorder. METHODS: Major depressive disorder and control groups consisted of 50 subjects. Plasma viscosity, erythrocyte aggregation, erythrocyte deformability, hematological parameters and hematological parameters were examined...
January 23, 2024: Clinical Hemorheology and Microcirculation
Georgios Sachsamanis, Julio Perez Delgado, Kyriakos Oikonomou, Wilma Schierling, Karin Pfister, Carl Zuelke, Thomas Betz
BACKGROUND: Prophylactic mesh implantation following open surgical repair of abdominal aortic aneurysm is a debatable subject. OBJECTIVE: To assess the efficacy of a self-gripping polyester mesh used in on-lay technique to prevent incisional hernia after open abdominal aortic aneurysm repair. METHODS: We retrospectively reviewed the records of 495 patients who underwent aortic surgery between May 2017 and May 2021. Patients included in the study underwent open surgical repair for infrarenal abdominal aortic aneurysm (AAA) with closure of the abdominal wall with either small bite suture technique or prophylactic mesh reinforcement...
January 20, 2024: Clinical Hemorheology and Microcirculation
Shen Zhang, Yunyun Liu, Bangguo Zhou, Huixiong Xu
OBJECTIVE: To evaluate the efficacy and safety of percutaneous ultrasound-guided thermal ablation in the treatment of cervical metastatic lymph nodes (LNs) from papillary thyroid carcinoma (PTC). MATERIALS AND METHODS: A total of 77 patients with 79 LNs ablated by microwave ablation (MWA) or radiofrequency ablation (RFA) between September 2018 and October 2022 were enrolled in this study. After treatment, patients were followed up with measurement of diameters of LNs and serum thyroglobulin (s-Tg) at 1, 3, 6, and 12 months and annually thereafter...
January 16, 2024: Clinical Hemorheology and Microcirculation
Matthew A Chatlaong, Daphney M Stanford, William M Miller, Chance J Davidson, Matthew B Jessee
BACKGROUND: Post-occlusive reactive hyperemia (PORH) typically requires caffeine abstinence. For habitual users, it is unknown if abstinence affects PORH. OBJECTIVE: Compare PORH after habitual users consume or abstain from caffeine. METHODS: On separate visits (within-subject), PORH was measured in 30 participants without abstinence from typical caffeine doses (CAFF) and with abstinence (ABS). Measurements included baseline and peak hyperemic velocity, tissue saturation index slopes during ischemia (Slope 1) and following cuff deflation (Slope 2), resting arterial occlusion pressure (AOP), heart rate (HR), systolic (SBP), and diastolic (DBP) blood pressure...
January 13, 2024: Clinical Hemorheology and Microcirculation
Mohammad Walid Al-Smadi, Laszlo Adam Fazekas, Adam Varga, Adam Attila Matrai, Siran Aslan, Anas Beqain, Mustafa Qais Muhsin Al-Khafaji, Barbara Bedocs-Barath, Laszlo Novak, Norbert Nemeth
BACKGROUND: Arteriovenous malformations (AVMs) are vascular anomalies characterized by abnormal shunting between arteries and veins. The progression of the AVMs and their hemodynamic and rheological relations are poorly studied, and there is a lack of a feasible experimental model. OBJECTIVE: To establish a model that cause only minimal micro-rheological alterations, compared to other AV models. METHODS: Sixteen female Sprague Dawley rats were randomly divided into control and AVM groups...
January 13, 2024: Clinical Hemorheology and Microcirculation
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