journal
https://read.qxmd.com/read/36931141/low-contralateral-neck-recurrence-risk-with-ipsilateral-neck-radiotherapy-in-n2b-tonsillar-squamous-cell-carcinoma
#1
JOURNAL ARTICLE
Divya Natesan, Christina K Cramer, Taofik Oyekunle, Donna Niedzwiecki, David M Brizel, Yvonne M Mowery
OBJECTIVES: To characterize factors including nodal burden, pre-treatment imaging, and other patient factors which may influence the role of ipsilateral neck radiotherapy (IRT) in tonsillar squamous cell carcinoma (SCC) with multiple involved ipsilateral nodes. METHODS: Patients with cT1-2N0-2bM0 (AJCC 7th edition) tonsillar SCC treated with definitive radiation therapy (RT) at Duke University Medical Center from 1/1/1990-10/1/2019 were identified. Patient, tumor, and treatment characteristics were compared between those that received bilateral neck RT (BRT) versus IRT...
March 15, 2023: Oral Oncology
https://read.qxmd.com/read/36924699/variance-in-3d-anatomic-localization-of-surgical-margins-based-on-conventional-margin-labeling-in-head-and-neck-squamous-cell-carcinoma
#2
JOURNAL ARTICLE
Raphael G Banoub, Meghan M Crippen, Michele A Fiorella, Heather M Ross, Emily S Sagalow, Voichita Bar-Ad, Dane Cohen, Stacey M Gargano, Madalina Tuluc, Yamil Selman, Richard Goldman, Elizabeth Cottrill, Adam Luginbuhl, Christopher Fundakowski, Leila J Mady, David Cognetti, Michael C Topf, Joseph M Curry
OBJECTIVE: In head and neck cancer (HNC), positive margins are strongly predictive of treatment failure. We sought to measure the accuracy of localization of margin sampling sites based on conventional anatomic labels using a digital 3D-model. METHODS: Preoperative CT scans for 9 patients with HNC treated operatively at our institution were imported into a multiplanar radiology software, which was used to render a digital 3D model of each tumor intended to represent the resection specimen...
March 14, 2023: Oral Oncology
https://read.qxmd.com/read/36905901/-cervical-metastasis-of-recurrent-pleomorphic-adenoma-of-the-submandibular-gland-a-new-perspective-for-multifocal-of-recurrent-pleomorphic-adenoma
#3
LETTER
Hao Lu, Shengwen Liu, Wanlin Xu, Wenjun Yang
No abstract text is available yet for this article.
March 9, 2023: Oral Oncology
https://read.qxmd.com/read/36905900/the-use-of-plasma-circulating-tumor-dna-for-early-detection-of-oligometastatic-disease-in-hpv-positive-oropharyngeal-squamous-cell-carcinoma
#4
LETTER
Lisa Zhang, Taylor Freeman, Shaoli Sun, Priyanka Bhateja, Jordan M Cloyd, James W Rocco, Catherine T Haring
No abstract text is available yet for this article.
March 9, 2023: Oral Oncology
https://read.qxmd.com/read/36881975/docetaxel-plus-radiotherapy-for-head-and-neck-cancer
#5
LETTER
Francesca De Felice
No abstract text is available yet for this article.
March 5, 2023: Oral Oncology
https://read.qxmd.com/read/36878144/surveillance-of-head-neck-cancer-case-for-personalized-and-standardized-surveillance
#6
LETTER
Shrikant B Mali
Although surgery, radiotherapy, chemotherapy, or combined treatment often elicits an initial satisfactory response, relapses are frequently observed within two years. Current surveillance methods, including clinical exams and imaging evaluations, have not unambiguously demonstrated a survival benefit, most probably due to a lack of sensitivity in detecting very early recurrence. Current guidelines advise post-treatment surveillance of head and neck cancer (HNC) patients should involve scheduled appointments with a variety of practitioners...
March 4, 2023: Oral Oncology
https://read.qxmd.com/read/36871349/next-generation-sequencing-ngs-profiling-of-matched-tumor-and-circulating-tumor-dna-ctdna-in-head-and-neck-squamous-cell-carcinoma-hnscc
#7
JOURNAL ARTICLE
Panagiota Economopoulou, Aris Spathis, Ioannis Kotsantis, Eirini Maratou, Maria Anastasiou, Myrto K Moutafi, Maria Kirkasiadou, Anastasios Pantazopoulos, Maria Giannakakou, Daniel L Edelstein, Hillary Sloane, Johannes Fredebohm, Frederick S Jones, Anastasios Kyriazoglou, Niki Gavrielatou, Periklis Foukas, Ioannis Panayiotides, Amanda Psyrri
OBJECTIVES: The aim of this pilot study was to evaluate the presence of somatic mutations in matched tumor and circulating DNA (ctDNA) samples from patients with primary head and neck squamous cell carcinoma (HNSCC) and assess the association of changes in ctDNA levels with survival. MATERIALS AND METHODS: Our study included 62 patients with stage I-IVB HNSCC treated with surgery or radical chemoradiotherapy with curative intent. Plasma samples were obtained at baseline, at the end of treatment (EOT), and at disease progression...
March 3, 2023: Oral Oncology
https://read.qxmd.com/read/36863309/upper-oral-cavity-tumors-is-the-risk-of-nodal-metastasis-different
#8
LETTER
B Arvind, Sanah Tazeen, Shalini Thakur, Vishal U S Rao
The state of the clinically evident cervical lymph nodes at the time of diagnosis is one of the most important factors impacting long-term survival. While squamous cell carcinomas (SCC) of the hard palate and maxillary alveolus are uncommon in comparison to other primary sites, there is a scarcity of published data on the effective management of the neck nodes for malignancies of these specific subsites. In such circumstances, an intraoperative frozen section or Sentinel node biopsy would aid in the optimal therapy of the neck...
February 28, 2023: Oral Oncology
https://read.qxmd.com/read/36842197/practice-patterns-for-initial-management-of-oral-leukoplakia-amongst-otolaryngologists-and-oral-and-maxillofacial-surgeons
#9
LETTER
Andrew C Birkeland, Deepak Kademani, Michael G Moore, Elizabeth A Blair
OBJECTIVE: Oral leukoplakia is encountered frequently by otolaryngologists and oral and maxillofacial surgeons (OMFS). There are no consensus practice management guidelines for oral leukoplakia, resulting in heterogeneity in practice patterns. Characterization of practice patterns of providers who treat oral leukoplakia will be valuable to establish standards of care and future practice guidelines. MATERIAL AND METHODS: A survey was designed by the American Head and Neck Society Cancer Prevention Service collecting demographic and practice management data for treating oral leukoplakia...
February 24, 2023: Oral Oncology
https://read.qxmd.com/read/36889240/incidence-and-medical-complications-of-covid-19-in-the-total-laryngectomy-population-a-population-based-study
#10
JOURNAL ARTICLE
Nilam D Patel, Claudia I Cabrera, Nicole M Fowler, Shawn Li, Jason E Thuener, Pierre Lavertu, Theodoros N Teknos, Rod P Rezaee, Akina Tamaki
OBJECTIVES: Laryngeal and hypopharyngeal cancers treated with total laryngectomy (TL) may provide a unique avenue for COVID-19 to infect cancer patients. The objective of this investigation was to identify incidence of COVID-19 infection and potential complications in TL patients. MATERIALS AND METHODS: Data was extracted from TriNetX COVID-19 research network from from 2019 to 2021 and ICD-10 codes were utilized to query for laryngeal or hypopharyngeal cancer, and outcomes of interest...
February 23, 2023: Oral Oncology
https://read.qxmd.com/read/36827901/a-new-prognostic-model-for-predicting-outcomes-of-patients-with-recurrent-or-metastatic-nasopharyngeal-carcinoma-receiving-subsequent-line-%C3%A2-2-lines-anti-programmed-death-1-monotherapy
#11
JOURNAL ARTICLE
Su-Chen Li, Shen-Wen Deng, Xue-Song Sun, Kai-Qi Lan, Chun-Yan Guo, Da-Feng Lin, Li-Ting Liu, Sai-Lan Liu, Hai-Qiang Mai, Lin-Quan Tang
OBJECTIVES: About 17.7-34.0 % of patients with recurrent or metastatic nasopharyngeal carcinoma (RM-NPC) responded well to anti-PD-1 monotherapy. We sought to establish a nomogram to estimate the progression-free survival (PFS) of RM-NPC patients receiving subsequent-line anti-PD-1 monotherapy. MATERIALS AND METHODS: This cohort study investigated consecutive RM-NPC patients undergoing anti-PD-1 monotherapy. A nomogram was developed in the training cohort (n = 161), using a Cox multivariate model with backward stepwise inclusion, and was validated in the validation cohort (n = 69)...
February 22, 2023: Oral Oncology
https://read.qxmd.com/read/36821984/a-case-of-liposarcoma-with-osteolysis-of-the-maxilla-as-the-first-symptom-and-review-of-the-literature
#12
JOURNAL ARTICLE
Yishen Kuang, Lizhong Liang, Xiangwei Li, Tong Li
Liposarcomas are extremely rare in the oral cavity and mainly observed in the buccal mucosa, tongue, floor of the mouth, gingiva, and lips, while those occurring in the jaws have not been reported so far. Clinically, the initial presentation of liposarcoma is usually a painless soft tissue mass. The aim of this study was to report a case of liposarcoma with osteolysis of the maxilla as the first symptom, and review the relevant literature to summarize its clinical features, imaging features, pathological features and treatment methods...
February 21, 2023: Oral Oncology
https://read.qxmd.com/read/36821983/flash-radiotherapy-gateway-to-promised-land-or-another-mirage
#13
LETTER
Shrikant B Mali, Sachinkumar Dahivelkar
Radiation therapy damages cancer cells with ionizing radiation, leading to their death. However, radiation‑induced toxicity limits the dose delivered to the tumor, thereby constraining the control effect of radiotherapy n tumor growth. In addition, the delayed toxicity caused by radiotherapy significantly harms the physical and mental health of patients. FLASH‑RT, an emerging class of radiotherapy, causes a phenomenon known as the 'FLASH effect', which delivers radiotherapy at an ultra‑high dose rate with lower toxicity to normal tissue than conventional radiotherapy to achieve local tumor control...
February 21, 2023: Oral Oncology
https://read.qxmd.com/read/36812716/letter-to-the-editor-quantification-of-the-force-applied-by-the-therabite%C3%A2-activeband%C3%A2
#14
LETTER
Emma Charters, Kai Cheng, Masako Dunn, Jonathan R Clark
No abstract text is available yet for this article.
February 20, 2023: Oral Oncology
https://read.qxmd.com/read/36807087/occult-nodal-metastases-in-t1-t2cn0-oral-squamous-cell-carcinoma-correlation-between-sentinel-node-positivity-and-completion-neck-dissection-analysis
#15
JOURNAL ARTICLE
J Guerlain, A Marhic, O Casiraghi, J Lumbroso, G Garcia, I Breuskin, F Janot, S Temam, P Gorphe, A Moya-Plana
OBJECTIVES: Sentinel node procedure (SN) is a standard procedure that has shown its safety and effectiveness for T1/T2 cN0 oral squamous cell carcinoma (OSCC), with completion neck dissection (CND) for patients with positive SN. The aim of this study was to characterize the nodal involvement in a cohort of SN + OSCC. MATERIALS AND METHODS: Patients with T1/T2 cN0 OSCC with positive SN with CND were included in this single-center, prospective cohort study between 2000 and 2013...
February 18, 2023: Oral Oncology
https://read.qxmd.com/read/36807086/magnetic-resonance-imaging-in-the-preoperative-evaluation-of-depth-of-invasion-in-oral-squamous-carcinoma-tongue-a-few-points-to-consider
#16
LETTER
Rupsa Das, Satya Ranjan Misra
No abstract text is available yet for this article.
February 18, 2023: Oral Oncology
https://read.qxmd.com/read/36773387/patient-derived-three-dimensional-culture-techniques-model-tumor-heterogeneity-in-head-and-neck-cancer
#17
REVIEW
Anuraag S Parikh, Victoria X Yu, Samuel Flashner, Ogoegbunam B Okolo, Chao Lu, Brian S Henick, Fatemeh Momen-Heravi, Sidharth V Puram, Theodoros Teknos, Quintin Pan, Hiroshi Nakagawa
Head and neck squamous cell carcinoma (HNSCC) outcomes remain stagnant, in part due to a poor understanding of HNSCC biology. The importance of tumor heterogeneity as an independent predictor of outcomes and treatment failure in HNSCC has recently come to light. With this understanding, 3D culture systems, including patient derived organoids (PDO) and organotypic culture (OTC), that capture this heterogeneity may allow for modeling and manipulation of critical subpopulations, such as p-EMT, as well as interactions between cancer cells and immune and stromal cells in the microenvironment...
February 9, 2023: Oral Oncology
https://read.qxmd.com/read/36780824/the-collateral-impact-of-the-covid-19-pandemic-on-hpv-positive-oropharyngeal-cancer-diagnosis
#18
JOURNAL ARTICLE
Yashi Ballal, Maru Gete, Jie Su, Brian O'Sullivan, John N Waldron, Jonathan Irish, Jolie Ringash, John Kim, Scott Bratman, John Cho, Andrew J Hope, Ali Hosni, John de Almeida, David P Goldstein, Ian Witterick, Eric Monteiro, Li Tong, Wei Xu, Shao Hui Huang, Ezra Hahn
PURPOSE: We aim to assess the potential impact of the COVID-19 pandemic on diagnostic delays in HPV-positive oropharyngeal cancer (OPC), and to describe their underlying reasons. METHODS: All HPV + OPC referred to a tertiary cancer centre and diagnosed between June-December 2019 (Pre-Pandemic cohort) vs June-December 2020 (Pandemic cohort) were reviewed. TNM classification, gross-tumor-volumes (GTV) and intervals between sign/symptom onset and treatment initiation were compared between the cohorts...
February 3, 2023: Oral Oncology
https://read.qxmd.com/read/36739689/small-cell-neuroendocrine-carcinoma-merkel-like-of-major-salivary-glands-presentation-of-a-multicenter-case-series-of-this-exceptional-histological-entity
#19
LETTER
Pietro De Luca, Matteo Simone, Daniele De Seta, Matteo Fermi, Alfredo Lo Manto, Gerardo Petruzzi, Arianna Di Stadio, Domenico Tassone, Luca de Campora, Aurelio D'Ecclesia, Alfonso Scarpa, Leopoldo Costarelli, Francesco Antonio Salzano, Daniele Marchioni, Raul Pellini, Livio Presutti, Angelo Camaioni
No abstract text is available yet for this article.
February 3, 2023: Oral Oncology
https://read.qxmd.com/read/36731348/metastatic-lymphoepithelial-carcinoma-of-the-parotid-gland-a-case-of-prolonged-response-with-platinum-gemcitabine-regimen
#20
LETTER
Audrey Rambeau, Asma Alidra, Adèle Riot
No abstract text is available yet for this article.
January 30, 2023: Oral Oncology
journal
journal
32771
1
2
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.