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Scandinavian Cardiovascular Journal: SCJ

Zahra Bahadoran, Parvin Mirmiran, Zhaleh Tahmasebinejad, Fereidoun Azizi, Asghar Ghasemi
OBJECTIVE: Limited data are available regarding prognostic value of nitric oxide metabolites (NOx) for clinical hard end points. In this study, we defined optimum cut-off values of serum NOx for predicting all-cause and cardiovascular disease (CVD) mortality events and prospectively investigated their hazards in the presence of traditional risk factors. DESIGN: Serum NOx concentrations were measured at baseline (2006-2008) and 3520 adult men and women were followed during 7...
May 13, 2019: Scandinavian Cardiovascular Journal: SCJ
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No abstract text is available yet for this article.
May 10, 2019: Scandinavian Cardiovascular Journal: SCJ
Joakim Nordanstig, Odd Bech-Hanssen, Per Skoog, Lennart Jivegård
OBJECTIVE: Skeletal muscle perfusion during walking relies on complex interactions between cardiac activity and vascular control mechanisms, why cardiac dysfunction may contribute to intermittent claudication (IC) symptoms. The study aims were to describe cardiac function at rest and during stress in consecutive IC patients, to explore the relations between cardiac function parameters and treadmill performance, and to test the hypothesis that clinically silent myocardial ischemia during stress may contribute to IC limb symptomatology...
May 7, 2019: Scandinavian Cardiovascular Journal: SCJ
Setor K Kunutsor, Timo H Mäkikallio, Jussi Kauhanen, Ari Voutilainen, Jari A Laukkanen
OBJECTIVES: Evidence from case-control studies as well as meta-analyses of these study designs suggest elevated lipoprotein(a) [Lp(a)] to be associated with an increased risk of venous thromboembolism (VTE). Prospective evidence on the association is limited, uncertain, and could be attributed to regression dilution bias. We aimed to assess the prospective association of Lp(a) with risk of VTE and correct for regression dilution. DESIGN: We related plasma Lp(a) concentrations to the incidence of VTE in 2,180 men of the Kuopio Ischemic Heart Disease cohort study...
April 27, 2019: Scandinavian Cardiovascular Journal: SCJ
Mikkel Giehm-Reese, Peter Lukac, Steen Buus Kristiansen, Henrik Kjaerulf Jensen, Christian Gerdes, Jens Kristensen, Jan Møller Nielsen, Mads Brix Kronborg, Jens Cosedis Nielsen
Objectives Left atrial flutter has been reported in up to 10% of patients following pulmonary vein isolation or cardiac surgery. Left atrial flutter is typically highly symptomatic, responds poorly to medical antiarrhythmic treatment, and is often treated by catheter ablation. We aimed to investigate midterm freedom from recurrent arrhythmia after catheter ablation for left atrial flutter. Design In the National Danish Ablation Registry, we identified consecutive patients, who had undergone catheter ablation for left atrial flutter between January 1st , 2014 and April 1st , 2017 at our centre...
April 27, 2019: Scandinavian Cardiovascular Journal: SCJ
Ting Wang, Zhenguo Liu, Jianli Fu, Zhiqian Min
OBJECTIVES: We performed a meta-analysis to determine whether vitamin D supplementation is beneficial in patients with chronic heart failure (CHF). DESIGN: Meta-analysis of randomised controlled trials. RESULTS: Vitamin D supplementation in patients with CHF improved health-related quality of life and C-reactive protein levels [weighted mean difference (WMD): 6.75, 95% confidence interval (CI): 2.87 to 10.64, P < 0.001; standardised mean difference (SMD): -0...
April 27, 2019: Scandinavian Cardiovascular Journal: SCJ
Jan Gofus, Martin Vobornik, Zdenek Sorm, Martin Dergel, Mikita Karalko, Jan Harrer, Marek Pojar
OBJECTIVES: Female sex has been generally accepted as a risk factor for short-term mortality and adverse events in surgical myocardial revascularization. However, there have been no data published yet about sex differences in minimally invasive settings. The aim of our study was to analyse short- and long- term outcomes of minimally invasive direct coronary artery bypass grafting (MIDCAB) in terms of sex comparison. DESIGN: We retrospectively analysed the in-hospital data of all patients (n = 384) undergoing MIDCAB at our department in years 2006-2016...
April 27, 2019: Scandinavian Cardiovascular Journal: SCJ
John Munkhaugen, Nils Tore Vethe, Morten Wang Fagerland, Toril Dammen, Joep Perk, Erik Gjertsen, Jan Erik Otterstad, Lars Gullestad, Stein Bergan, Einar Husebye
Objectives Estimate the effect of atorvastatin on muscular symptom intensity in coronary patients with subjective statin-associated muscle symptoms (SAMS) and to determine the association with blood levels of atorvastatin and its metabolites, to obtain an objective marker for true SAMS. Design A randomized, double-blinded, cross-over study will include 80 coronary patients with subjectively reported SAMS during ongoing atorvastatin therapy or previous muscle symptoms that led to discontinuation of atorvastatin...
April 27, 2019: Scandinavian Cardiovascular Journal: SCJ
Tae Jung Kim, Jinyoung Song, Yi-Seul Kim, June Huh, I-Seok Kang, Ji-Hyuk Yang, Tae-Gook Jun
OBJECTIVES: We aimed to investigate the outcome of tricuspid valve repair (TVR) performed concomitantly with pulmonary valve replacement in repaired tetralogy of Fallot (TOF) patients. DESIGN: This retrospective study included all patients who underwent pulmonary vale replacement from 2000 to 2016 after TOF correction. TVR patient data were compared to those of patients who underwent pulmonary vale replacement alone. RESULTS: Thirty-eight patients were enrolled...
April 24, 2019: Scandinavian Cardiovascular Journal: SCJ
Giuseppe Gatti, Sandro Sponga, Maddalena Peghin, Filippo Givone, Veronica Ferrara, Bernardo Benussi, Enzo Mazzaro, Andrea Perrotti, Matteo Bassetti, Roberto Luzzati, Sidney Chocron, Aniello Pappalardo, Ugolino Livi
OBJECTIVES: To evaluate scoring systems that have been created to predict the risk of death post-surgery in infective endocarditis (IE). DESIGN: Eight scores - (1) The Society of Thoracic Surgery (STS) risk score for IE, (2) De Feo score, (3) PALSUSE score (prosthetic valve, age ≥70, large intracardiac destruction, Staphylococcus spp, urgent surgery, sex [female], EuroSCORE ≥10), (4) ANCLA score (anemia, New York Heart Association class IV, critical state, large intracardiac destruction, surgery of thoracic aorta), (5) Risk-Endocarditis Score (RISK-E), (6) score for heart valve or prosthesis IE (EndoSCORE), and (7,8) Association pour l'Étude et la Prévention de l'Endocadite Infectieuse (AEPEI) score I and II - were evaluated in 324 (mean age, 61...
April 22, 2019: Scandinavian Cardiovascular Journal: SCJ
Julian Müller, Michael Behnes, Dominik Ellguth, Tobias Schupp, Kambis Mashayekhi, Martin Borggrefe, Ibrahim Akin
OBJECTIVES: The study sought to assess the prognostic impact of recurrences of electrical storm (ES-R) on mortality, rehospitalization and major adverse cardiac events (MACE). BACKGROUND: Data on the prognostic impact of ES-R is rare. METHODS: All consecutive ES patients with implantable cardioverter defibrillator (ICD) were included retrospectively from 2002 to 2016. Patients with ES-R were compared to patients without ES-R. The primary prognostic endpoint was all-cause mortality, secondary endpoints were in-hospital mortality, rehospitalization rates and MACE...
April 8, 2019: Scandinavian Cardiovascular Journal: SCJ
Sabreen Mkalaluh, Marcin Szczechowicz, Matthias Karck, Gabor Szabo
BACKGROUND: Acute massive pulmonary embolism is often a life-threatening condition and should be treated immediately. The aim of this study was to investigate risk factors and clinical outcomes of patients undergoing emergency pulmonary embolectomy for acute massive pulmonary embolism. METHODS: We evaluated 49 patients undergoing emergency pulmonary embolectomy in our institution between 1995 and 2015, retrospectively. We reviewed preoperative conditions and risk factors, surgical complications, postoperative courses, predictors of mortality and long-term survival...
March 28, 2019: Scandinavian Cardiovascular Journal: SCJ
Danielle M Haanschoten, Jaap Jan J Smit, Ahmet Adiyaman, Anand R Ramdat Misier, Peter Paul Hm Delnoy, Arif Elvan
OBJECTIVES: Severe LV dysfunction and advanced age are associated with VT recurrence after catheter ablation in patients with post-infarction drug-refractory VT. We present retrospective analysis of long-term outcome after single and repeat VT ablation procedures in patients with ischemic heart disease. DESIGN: Patients with recurrent VT post infarction who underwent catheter ablation between 2006 and 2017 in Isala Heart Centre were retrospectively analyzed. Univariate and multivariate analysis were used to identify predictors of arrhythmia recurrence post ablation...
March 27, 2019: Scandinavian Cardiovascular Journal: SCJ
Yu Wu, Yimiao Song, Yuesong Pan, Yong Gong, Yilun Zhou
BACKGROUND: The efficacy of clopidogrel is often attenuated in the setting of renal impairment. High on-treatment platelet reactivity (HPR) is an independent correlate of adverse event. Here we performed a quantitative evaluation of the prevalence and impact of HPR in patients with chronic kidney disease (CKD). METHODS: We systematically searched PubMed, EMBASE and the Cochrane Library from their inception to 1 March 2018 for cohort studies assessing the risk ratio (RR) of prevalence of HPR in CKD versus non-CKD patients and association of cardiovascular outcome with HPR in CKD patients treated with clopidogrel...
March 26, 2019: Scandinavian Cardiovascular Journal: SCJ
Christina Antza, Ioannis Doundoulakis, Evangelos Akrivos, Fotios I Economou, Polychronis Vazakidis, Anna-Bettina Haidich, Vasilios Kotsis
OBJECTIVES: We conducted a systematic review and network meta-analysis of randomized controlled trials (RCTs) including the comparison of non-vitamin K antagonist oral anticoagulants (NOACs) with warfarin for patients with atrial fibrillation (AF). DESIGN: Network meta-analysis. Two authors independently extracted data. All authors evaluated overall confidence in the evidence. RESULTS: Eighteen RCTs included in our review, a total of 78,796 patients with AF, with sample sizes from 90 to 21,105 patients...
March 21, 2019: Scandinavian Cardiovascular Journal: SCJ
Jahangir Khan, Niina Khan, Ari Mennander
OBJECTIVES: To ascertain whether extended chest tube drainage decreases the occurrence of late tamponade after cardiac surgery. DESIGN: All patients undergoing cardiac surgery at the Tampere University Heart Hospital, Tampere, Finland, between the 23rd of October 2015 and the 17th of August 2016 were included. The first 260 consecutive patients were treated according to a short drainage protocol, in which the mediastinal chest tubes were removed during the first postoperative day unless producing >50ml/h, and the following 224 consecutive patients by an extended drainage protocol, in which the mediastinal chest tubes were kept at least until the second postoperative day, and thereafter if producing >50ml/4h...
March 5, 2019: Scandinavian Cardiovascular Journal: SCJ
Aaron Koshy, Nduka C Okwose, David Nunan, Anet Toms, David A Brodie, Patrick Doherty, Petar Seferovic, Arsen Ristic, Lazar Velicki, Nenad Filipovic, Dejana Popovic, Jane Skinner, Kristian Bailey, Guy A MacGowan, Djordje G Jakovljevic
OBJECTIVES: Heart rate variability (HRV) and haemodynamic response to exercise (i.e. peak cardiac power output) are strong predictors of mortality in heart failure. The present study assessed the relationship between measures of HRV and peak cardiac power output. DESIGN: In a prospective observational study of 33 patients (age 54 ± 16 years) with chronic heart failure with reduced left ventricular ejection fraction (29 ± 11%), measures of the HRV (i.e...
March 5, 2019: Scandinavian Cardiovascular Journal: SCJ
Tufan Çınar, Metin Çağdaş, İbrahim Rencüzoğulları, Süleyman Karakoyun, Yavuz Karabağ, Mahmut Yesin, Öznur Sadioğlu Çağdaş, Halil İbrahim Tanboğa
OBJECTIVE: Although the prognostic efficacy of C-reactive protein (mg/L) and albumin levels (g/L) has been previously associated with poor prognosis in ST elevation myocardial infarction (STEMI), to the best of our knowledge, the prognostic efficacy of C-reactive protein/Albumin ratio (CAR) (mg/g) has not been investigated yet. Thus, this study aimed to investigate the potential efficacy of the CAR in predicting prognosis in STEMI patients. METHOD: We conducted a detailed investigation of 2437 patients with first STEMI treated with a primary percutaneous coronary intervention...
March 5, 2019: Scandinavian Cardiovascular Journal: SCJ
Emil Najjar, Ulrika Ljung Faxén, Camilla Hage, Erwan Donal, Jean-Claude Daubert, Cecilia Linde, Lars H Lund
OBJECTIVES: Soluble suppression of tumorigenecity 2 (sST2) is prognostic in acute and chronic heart failure with reduced ejection fraction (HFrEF) but less studied in HF with preserved EF (HFpEF). We evaluated sST2 concentrations, correlations with biomarkers and echocardiographic measures of diastolic and systolic function, and associations with outcomes in HFpEF and HFrEF. DESIGN AND RESULTS: A total of 193 subjects from three different cohorts were included. Eighty-six HFpEF patients were obtained from the Karolinska Rennes (KaRen) study, 86 patients with HFrEF were recruited from referrals to Karolinska University Hospital for advanced assessment of HF, and 21 controls were included (ClinicalTrials...
February 19, 2019: Scandinavian Cardiovascular Journal: SCJ
Torkel Steen, Elena Sciaraffia, Camilla Normand, Nigussie Bogale, Kenneth Dickstein, Cecilia Linde, Berit T Philbert
OBJECTIVES: To compare the contemporary practice of CRT implantation in Scandinavia and Europe. DESIGN: We used data from The European CRT Survey II to highlight similarities and differences in the practice of CRT implantation between Europe (EUR) and Scandinavia (SCAND) and between the Scandinavian countries Denmark, Norway and Sweden. Implant data from the national pacemaker registries were used to calculate coverage. RESULTS: The coverage was 24% in SCAND and 11% in EUR...
February 14, 2019: Scandinavian Cardiovascular Journal: SCJ
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