Huimin Zhu, Xiaodong Jia, Zhenjuan Fang, Chengyi Zhang, Ningning Wang, Haoxiao Chang, Wei-Na Jin, Fu-Dong Shi, Wenyan He
BACKGROUND: Brain injury triggers neuroaxonal injury and neural death, that leads to the development of secondary sequelae. Throughout this process, brain injury factors released into circulation via the injured neurovascular unit are important prognostic parameters. Plasma NfL, NfH, MCP-1, and MMP-9 have been identified as potential indicators in this regard. METHODS: Using a microfluidic ELISA platform, we measured plasma from 273 healthy subjects that underwent quantifications of NfL, NfH, MCP-1, and MMP-9 levels...
November 1, 2023: Clinical Laboratory