Eugenia Giuliani, Francesca Rollo, Carlo Cota, Tarik Gheit, Luisa Galati, Sandrine McKay-Chopin, Marinella Tedesco, Emilia Migliano, Maria Benevolo, Aldo Morrone, Maria Gabriella Donà, Alessandra Latini
BACKGROUND: Lichen sclerosus (LS) is an inflammatory disease mostly arising at the genital level. It is unclear whether human papillomaviruses (HPVs) have an etiological significance in LS, and data on their prevalence in patients with LS are controversial. OBJECTIVES: We assessed alpha, beta, and gamma HPV prevalence in patients with genital LS. The association of HPV positivity with demographic and clinical factors was also investigated. METHODS: One hundred thirty-two formalin-fixed, paraffin-embedded LS samples (2016-2020) were retrieved from the archives of a pathology department...
April 13, 2023: Journal of Lower Genital Tract Disease