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Journals Journal of Lower Genital Tract...

Journal of Lower Genital Tract Disease

https://read.qxmd.com/read/38864720/long-term-effectiveness-of-vestibulectomy-for-the-treatment-of-vulvodynia-a-retrospective-cohort-study
#1
JOURNAL ARTICLE
Nele Coryn, Bart Vergauwe, Steven Weyers, Hans Verstraelen
OBJECTIVE: To evaluate the effectiveness and complication rate of vestibulectomy for vulvodynia. METHODS: A retrospective cohort study in a teaching and university hospital analyzing patients with vulvodynia with insufficient response to conservative treatment who underwent a vestibulectomy. Data from 114 consecutive vestibulectomy procedures done between September 2009 and October 2018 were retrospectively analyzed. All procedures were performed by the same surgeon...
June 12, 2024: Journal of Lower Genital Tract Disease
https://read.qxmd.com/read/38713522/deep-learning-diagnostic-classification-of-cervical-images-to-augment-colposcopic-impression
#2
JOURNAL ARTICLE
André Aquilina, Emmanouil Papagiannakis
OBJECTIVE: A deep learning classifier that improves the accuracy of colposcopic impression. METHODS: Colposcopy images taken 56 seconds after acetic acid application were processed by a cervix detection algorithm to identify the cervical region. We optimized models based on the SegFormer architecture to classify each cervix as high-grade or negative/low-grade. The data were split into histologically stratified, random training, validation, and test subsets (80%-10%-10%)...
May 7, 2024: Journal of Lower Genital Tract Disease
https://read.qxmd.com/read/38709568/outcome-measures-in-adult-vulvar-lichen-sclerosus-a-systematic-review
#3
JOURNAL ARTICLE
Beth Morrel, Marianne J Ten Kate-Booij, Charlotte van Dijk, Wichor M Bramer, Curt W Burger, Suzanne G M A Pasmans, Irene A M van der Avoort
OBJECTIVES: Core outcome domains (CODs) for treatment of adult vulvar lichen sclerosus (VLS) have recently been established through a Delphi study. A number of measuring tools are available for evaluating VLS. The aim of this study is to identify available standardized measurement tools for the major CODs for VLS that have recently been defined, namely, physical findings and quality of life (QoL) specific to VLS. MATERIALS AND METHODS: A systematic search through September 8, 2023, for measuring tools applicable to VLS regarding physical findings and QoL including sexual function or sexual well-being and self-image was performed...
May 7, 2024: Journal of Lower Genital Tract Disease
https://read.qxmd.com/read/38709567/outcome-measures-in-adult-vulvar-lichen-sclerosus-a-case-series-of-women-diagnosed-as-juveniles
#4
JOURNAL ARTICLE
Beth Morrel, Marianne J Ten Kate-Booij, Charlotte van Dijk, Colette L M van Hees, Kiki M G J Wigny, Curt W Burger, Suzanne G M A Pasmans, Irene A M van der Avoort
OBJECTIVES: Studies on the consequences of juvenile vulvar lichen sclerosus (JVLS) in adulthood are limited. A number of measuring tools are available for analyzing adult vulvar lichen sclerosus (VLS), but these have not been applied in studies on JVLS. The aim is to study physical findings, quality of life, sexual well-being, and self-image in adult women with a history of juvenile VLS. MATERIALS AND METHODS: Adult women with a biopsy proven history of JVLS were recruited to be examined and surveyed using available standardized measurement tools...
May 7, 2024: Journal of Lower Genital Tract Disease
https://read.qxmd.com/read/38709565/distribution-and-severity-of-cervical-intraepithelial-neoplasia-in-women-with-different-human-papillomavirus-an-analysis-from-liaoning-province-of-northeastern-china
#5
JOURNAL ARTICLE
Xin Wei, Yi-Hang Zhou, Peng Chen
OBJECTIVE: Persistent infection with high-risk human papillomavirus (HPV) is a key contributor to cervical intraepithelial neoplasia (CIN), but the relation between high-risk HPV genotypes and the location of CIN lesions remains unclear. The aims of this study were to investigate the most frequent biopsy site of CIN lesions in women with different HPV infection and to analyze the biopsy times, CIN frequency, and the clustering of CIN frequency based on 12-o'clock sites and cervical quadrant locations...
May 6, 2024: Journal of Lower Genital Tract Disease
https://read.qxmd.com/read/38709111/factors-associated-with-recent-decline-in-anal-health-among-older-gay-and-bisexual-men-a-cross-sectional-analysis
#6
JOURNAL ARTICLE
Sian L Goddard, I Mary Poynten, Kathy Petoumenos, Fengyi Jin, Richard J Hillman, Christopher K Fairley, Suzanne M Garland, Andrew E Grulich, David J Templeton
We investigated factors associated with "worse than usual" anal health among gay and bisexual men aged ≥35 years recruited to a longitudinal study of anal human papillomavirus infection/lesions from September 2010 to August 2015.Among 616 participants (median age 49 years; 36% HIV-positive), 42 (6.8%) reported worse than usual anal health in the last 4 weeks. Associated factors included spending less time with gay friends (odds ratio [OR] = 2.25, 95% CI = 1.06-4.77), most time "feeling down"(OR = 9.17, 95% CI = 2...
May 6, 2024: Journal of Lower Genital Tract Disease
https://read.qxmd.com/read/38697130/time-differences-from-abnormal-cervical-cancer-screening-to-colposcopy-between-insurance-statuses
#7
JOURNAL ARTICLE
Sonia Khurana, Isaiah Smolar, Leslie Warren, Jessica Velasquez, Elianna Kaplowitz, Jeanette Rios, Adriana Pero, Harley Roberts, Mackenzie Mitchell, Ceyda Oner, Cynthia Abraham
OBJECTIVE: Screening and diagnostic follow-up to prevent cervical cancer are influenced by socioeconomic and systemic factors. This study sought to characterize intervals from abnormal cervical cancer screening to colposcopy between practices differing by insurance status at a large, urban academic center. MATERIALS AND METHODS: This retrospective cohort study included patients aged 21-65 who presented for colposcopy between January 1, 2021, and January 1, 2022, at the resident and faculty gynecology practices of a single large urban academic medical center...
May 2, 2024: Journal of Lower Genital Tract Disease
https://read.qxmd.com/read/38697129/a-scoping-review-of-complementary-and-alternative-medicine-for-human-papillomavirus-infections-and-cervical-dysplasia
#8
JOURNAL ARTICLE
Caroline J Walsh, Julie C Friedman, Christine Conageski, Christi Piper
OBJECTIVE: The goal of this scoping review is to synthesize clinically relevant scientific literature on current complementary and alternative medications that address human papillomavirus (HPV) infections and cervical dysplasia. MATERIALS AND METHODS: A systematic search of published studies was performed December 2021 for the following concepts: human papilloma virus, cervical dysplasia, and complementary and alternative medicine (CAM). Relevant publications were identified by searching Ovid MEDLINE ALL, Embase, Cochrane Library, AMED, and MEDLINE databases, in addition to clinical trial databases...
May 2, 2024: Journal of Lower Genital Tract Disease
https://read.qxmd.com/read/38697126/psychosocial-factors-associated-with-vulvodynia
#9
JOURNAL ARTICLE
Janice F Queiroz, Antonio C Q Aquino, Ayane C A Sarmento, Beatriz B Siqueira, Heitor D Medeiros, Megan L Falsetta, Tracey Maurer, Ana Katherine Gonçalves
OBJECTIVES: We set out to identify the psychosocial factors associated with vulvodynia and the effects on sexuality, mental health, and quality of life. MATERIALS AND METHODS: PubMed, LILACS, Embase, CINAHL, Web of Science, Scopus, and PsycINFO were searched in August 2023. Two authors selected and extracted the data independently. The risk of bias was assessed using the Newcastle-Ottawa Scale for Observational Studies. To rank the strength of evidence, the Grading of Recommendations Assessment, Development and Evaluation Working Group (GRADE) approach was utilized...
May 2, 2024: Journal of Lower Genital Tract Disease
https://read.qxmd.com/read/38661377/commonly-drawn-immunologic-and-inflammatory-markers-as-risk-predictors-for-anal-cancer-in-veterans-living-with-hiv
#10
JOURNAL ARTICLE
Jonathan Stem, Austin J Hewitt, Qiuyu Yang, Cristina B Sanger
OBJECTIVES: This study aimed to determine if immune inflammatory markers (neutrophil lymphocyte ratio [NLR], platelet lymphocyte ratio [PLR], and prognostic nutritional index [PNI]) correlate with anal cancer risk in people living with HIV and to compare these markers with the CD4/CD8 ratio. MATERIALS AND METHODS: This is a regional retrospective cohort study of veterans living with HIV who were screened for or diagnosed with anal neoplasia or cancer from 2001 to 2019...
April 24, 2024: Journal of Lower Genital Tract Disease
https://read.qxmd.com/read/38661363/efficacy-of-a-triticum-vulgare-extract-as-a-treatment-of-cervical-ectropion-a-prospective-observational-cohort-study
#11
JOURNAL ARTICLE
Paolo Manna, Alessandra Gallo, Giovanna Bitonti, Roberta Venturella, Costantino Di Carlo
OBJECTIVES: To assess the effectiveness of a topical treatment for cervical ectropion with vaginal ovules containing aqueous extract of Triticum vulgare. METHODS: Prospective observational cohort study conducted between November 2020 and November 2022 at the colposcopy clinics of 2 different hospitals. Sexually active patients with a colposcopic diagnosis of cervical ectropion, awaiting ablative procedure, were included in the study and prescribed medical therapy with vaginal T...
April 24, 2024: Journal of Lower Genital Tract Disease
https://read.qxmd.com/read/38661348/a-longitudinal-multiinstitutional-study-of-vulvar-lichen-sclerosus-from-childhood-to-perimenopause
#12
JOURNAL ARTICLE
Jacopo Di Giuseppe, Giovanni Delli Carpini, Luca Giannella, Tomas Terenzi, Mariasole Fichera, Federica Ragno, Anna Campanati, Veronica Boero, Carlotta Caia, Elisa Pesce, Paolo Vercellini, Barbara Gardella, Mattia Dominoni, Arsenio Spinillo, Francesco Sopracordevole, Nicolò Clemente, Anna Del Fabro, Riccardo Rossi, Monica Corazza, Alessandro Borghi, Ruby Martinello, Pantaleo Greco, Giuseppe Rizzo, Anna Angela Criscuolo, Ilenia Mappa, Enrico Matteini, Elisabetta Botti, Elena Campione, Luca Bianchi, Andrea Ciavattini
OBJECTIVE: The main outcome of this study was the evaluation of clinical characteristics, comorbidities, and therapeutic approaches in patients with vulvar lichen sclerosus (VLS) aged from childhood to perimenopause. Secondly, it was intended to compare these characteristics according to the menarchal status. METHODS: Patients less than 45 years of age with a diagnosis of VLS from January 2002 to June 2022 in 10 referral centers were included in this retrospective longitudinal study...
April 24, 2024: Journal of Lower Genital Tract Disease
https://read.qxmd.com/read/38661333/hpv-vaccination-practices-among-medical-trainees-in-pediatrics-obstetrics-and-gynecology-and-family-medicine
#13
JOURNAL ARTICLE
Kayla J Cagle-Colon, Paxton Voigt, Leslie Boyd
OBJECTIVE: The human papillomavirus (HPV) vaccine has been proven effective in preventing HPV-related cancer. However, vaccination uptake in the United States remains unacceptably low. The aim of this study is to determine whether residents' HPV vaccination status, demographics, or residency training setting are predictive of vaccination prescribing practices. METHODS: This was an anonymous, IRB-approved, opt-in survey of OBGYN, Family Medicine, and Pediatric residents...
April 23, 2024: Journal of Lower Genital Tract Disease
https://read.qxmd.com/read/38661331/the-incidence-of-cervical-intraepithelial-neoplasia-or-cervical-cancer-in-women-referred-with-postcoital-bleeding
#14
JOURNAL ARTICLE
Hajer Mohammad, Anne Sofie Espensen, Margrét Björg Arnardóttir, Stinne Holm Bergholdt, Lone Kjeld Petersen
OBJECTIVES: The incidence of cervical cancer among patients with postcoital bleeding (PCB) was the primary objective of this study. Furthermore, the proportion of cervical intraepithelial neoplasia requiring treatment and the correlation between PCB and the presence of high-risk human papillomavirus (HPV) was determined. Lastly, the study aimed to identify risk factors among the referred women. METHODS: A retrospective cohort study was conducted at a university hospital in Denmark between January 1, 2017 and December 31, 2019...
April 23, 2024: Journal of Lower Genital Tract Disease
https://read.qxmd.com/read/38518219/treatment-of-refractory-vulvar-lichen-sclerosus-with-methotrexate
#15
JOURNAL ARTICLE
Afsoon Ghafari-Saravi, Erin Foster
We report the successful treatment of severe vulvar lichen sclerosus refractory to topical corticosteroids in 3 adult female patients using low-dose oral methotrexate. All cases reported symptomatic and clinical improvement within 12 weeks.
April 1, 2024: Journal of Lower Genital Tract Disease
https://read.qxmd.com/read/38518218/argon-plasma-coagulation-as-treatment-for-anal-condylomas-a-narrative-review
#16
JOURNAL ARTICLE
Andreia Albuquerque
OBJECTIVES: Anal condylomas are a manifestation of anal human papillomavirus infection and can be associated with precancerous lesions and squamous cell carcinomas. Several methods have been described for treatment, including argon plasma coagulation. A narrative review of the evidence published on this topic was conducted. METHODS: A search was conducted using PubMed, Scopus, and Web of Science databases. RESULTS: Five studies reported on anal/perianal condyloma treatment with argon plasma coagulation...
April 1, 2024: Journal of Lower Genital Tract Disease
https://read.qxmd.com/read/38518217/vulvar-lichenoid-dermatoses-with-emphasis-on-the-distinction-between-lichen-sclerosus-and-lichen-planus-a-10-year-study
#17
JOURNAL ARTICLE
Sueallen Lorna D'Souza, Gayatri Ravikumar, Meryl Antony, Rajalakshmi Tirumale
OBJECTIVES: Lichen planus (LP) and lichen sclerosus (LS) are the most common vulvar lichenoid dermatoses. The diagnostic challenges are due to site-specific variation in microscopic appearance and small-sized biopsies. Authentication of diagnostic criteria to distinguish LS and LP to uncover any resemblance or divergence in presentation of these conditions is attempted. METHODS: Cases of vulvar LP and LS diagnosed between January 2012 to December 2022 were included...
April 1, 2024: Journal of Lower Genital Tract Disease
https://read.qxmd.com/read/38518216/attitudes-toward-proactive-topical-corticosteroid-use-among-women-with-vulval-lichen-sclerosus
#18
JOURNAL ARTICLE
Sophie Rees, Susanne Arnold, Ashod Kherlopian, Gayle Fischer
OBJECTIVES: Some practitioners are adopting proactive topical corticosteroid (TCS) therapy for vulval lichen sclerosus (VLS). We sought to understand patient attitudes toward proactive TCS therapy for VLS in a context in which proactive therapy is adopted. METHODS: Four online focus group discussions with 12 participants. Data analysis was informed by social constructionist grounded theory. RESULTS: All participants had accepted a proactive regimen...
April 1, 2024: Journal of Lower Genital Tract Disease
https://read.qxmd.com/read/38518215/clinicopathologic-overlap-of-vulvar-psoriasis-and-candidiasis
#19
JOURNAL ARTICLE
Tania Day, Erika Chapman-Burgess, James Scurry
OBJECTIVES: The study's aim is to assess if vulvar psoriasis and candidiasis may be distinguished by clinical presentation and histopathologic appearance. METHODS: The pathology database identified biopsies with corneal or subcorneal neutrophils, acanthosis, and dermal lymphocytic infiltrate. Exclusions were age younger than 18 years and unavailable or uninterpretable slides. Clinical data included demographics, comorbid conditions, symptoms, examination, microbiology, treatment, and response...
April 1, 2024: Journal of Lower Genital Tract Disease
https://read.qxmd.com/read/38518214/risk-factors-for-lichen-sclerosus-a-case-control-study-of-43-000-finnish-women
#20
JOURNAL ARTICLE
Pia Halonen, Oskari Heikinheimo, Kishor Hadkhale, Mika Gissler, Eero Pukkala, Maija Jakobsson
OBJECTIVES: Lichen sclerosus (LS) is an inflammatory skin disease probably arising from an interplay of genetics, local irritation, and autoimmune processes. We identified potential risk factors for the disease using data from nationwide Finnish registries. METHODS: We identified all women diagnosed with LS within specialized health care during 1998-2016 (n = 10,692) and selected 3 age-matched population control women for each case. We calculated odds ratios (ORs) for possible risk factors using conditional logistic regression...
April 1, 2024: Journal of Lower Genital Tract Disease
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