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Dermatologic Therapy

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https://read.qxmd.com/read/30767395/fluorescence-advanced-videodermatoscopy-a-promising-and-potential-technique-for-the-in-vivo-evaluation-of-vitiligo
#1
LETTER
Federica Scarfì, Alessia Gori, Flavia Silvestri, Luciana Trane, Francesca Portelli, Pierandrea Maida, Emi Dika, Paolo Broganelli, Daniela Massi, Vincenzo De Giorgi
No abstract text is available yet for this article.
February 14, 2019: Dermatologic Therapy
https://read.qxmd.com/read/30758911/infective-endocarditis-in-two-patients-with-pemphigus-vulgaris-under-multiagent-immunosuppressive-drug-therapy-a-rare-entity-to-remember-in-the-differential-diagnosis-of-fever-of-unknown-origin
#2
Rıfkiye Küçükoğlu, Sıla Kılıç, Gizem Pınar Sun
Pemphigus vulgaris (PV) is an autoimmune blistering skin disease that, may require multiagent immunosuppressive drug therapies in severe cases. In addition to the well established corticosteroid sparing agents azathioprine, mycophenolate mofetil, and methotrexate, rituximab is being increasingly used alone or in combination in the management of PV. Due to the chronic course of the disease, the cumulative effects of these therapy agents over long follow-up periods may result in various adverse reactions, including bacterial and viral infections...
February 13, 2019: Dermatologic Therapy
https://read.qxmd.com/read/30758908/efficacy-and-safety-of-secukinumab-in-a-psoriatic-patient-affected-by-comorbid-metabolic-disorders
#3
LETTER
Graziella Babino, Elisabetta Fulgione, Caterina Mariarosaria Giorgio, Marina Agozzino, Roberto Alfano, Giuseppe Argenziano
No abstract text is available yet for this article.
February 13, 2019: Dermatologic Therapy
https://read.qxmd.com/read/30758903/treatment-of-injection-induced-ecchymoses-with-light-laser-assisted-technology
#4
Ines Verner, Hadas Prag Naveh, Dario Bertossi
An increasing number of minimally invasive cosmetic procedures, such as filler or botulinum toxin injections, are performed annually. These procedures are associated with a high risk of post-procedure bruising or ecchymosis. Ecchymoses arise following hemorrhage and extravasation of red blood cells into the subcutaneous tissue, leading to local skin discoloration. Although ecchymoses generally resolve within 14 days, their appearance is cosmetically bothersome, and they may be painful and cause major distress to patients...
February 13, 2019: Dermatologic Therapy
https://read.qxmd.com/read/30758895/syphilis-with-charcot-arthropathy-a-case-report
#5
Menglei Wang, Rongrong Huang, Li Wang, Nasha Yu, Li Li
Syphilis is a chronic systemic infectious disease involving multiple organs. Involvement of skeletal system by syphilis including osteochondritis, osteoarthritis, periostitis and osteitis. Charcot arthropathy is an unusual concomitant disease of syphilis, and the incidence had decreased significantly these decades. We report a case of syphilis presenting with Charcot arthropathy of bilateral ankle joints. This article is protected by copyright. All rights reserved.
February 13, 2019: Dermatologic Therapy
https://read.qxmd.com/read/30756448/intravenous-immunoglobulin-treatment-where-do-dermatologists-stand
#6
LETTER
Selma Emre
Intravenous immunoglobulins are therapeutic products, comprising polyclonal IgGs, which are obtained from human plasma pool of healthy blood donors. Despite the lack of FDA approval, the experience of using IVIG in various dermatological diseases increases day by day and exciting results are reported. However, experience with the use of IVIG in dermatological indications are mostly case reports whereas randomized, controlled, double-blind, multicentric studies have not been performed. Dermatological diseases treated with IVIG are autoimmune bullous skin diseases, Stevens-Johnson syndrome and toxic epidermal necrolysis, connective tissue diseases, pyoderma gangrenosum, severe atopic dermatititis, chronic urticaria, Kawasaki disease, pretibial myxoedema, scleredema and graft-versus-host disease...
February 13, 2019: Dermatologic Therapy
https://read.qxmd.com/read/30748085/infliximab-improved-the-refractory-cutaneous-involvement-in-a-patient-with-dermatomyositis
#7
LETTER
Saori Yamada-Kanazawa, Ikko Kajihara, Atsuko Kobayashi, Chinatsu Watanabe, Hironobu Ihn
No abstract text is available yet for this article.
February 12, 2019: Dermatologic Therapy
https://read.qxmd.com/read/30748080/how-reflectance-confocal-microscopy-can-help-diagnose-an-enigmatic-variant-of-dermatofibroma
#8
LETTER
Caterina Mazzella, Alessia Villani, Massimiliano Scalvenzi, Gabriella Fabbrocini, Mariateresa Cantelli, Claudia Costa
No abstract text is available yet for this article.
February 12, 2019: Dermatologic Therapy
https://read.qxmd.com/read/30748073/capecitabine-induced-eruptive-acral-hyperpigmentation-clinical-and-dermoscopic-evaluation-of-two-cases
#9
LETTER
Francesca Peccerillo, Riccardo Pampena, Luca Giannetti, Giovanni Pellacani, Caterina Longo
No abstract text is available yet for this article.
February 12, 2019: Dermatologic Therapy
https://read.qxmd.com/read/30748068/new-therapeutic-options-in-the-management-of-superficial-fungal-diseases
#10
Duriye Deniz Demirseren
Superficial fungal infections which effect the skin, hair, and nails, are widely observed in the world. Causative agents are Candida species, dermatophytes, and Malassezia species. In recent years new antifungal agents and formulations have been developed for these infections. In addition laser therapies have been tried for onychomycosis. There are also studies on the antifungal activity of some herbs and propolis. In this paper, relatively new treatment methods of superficial fungal infections will be described...
February 12, 2019: Dermatologic Therapy
https://read.qxmd.com/read/30748065/psoriasis-with-a-dirt-adherent-a-rare-case-report
#11
Ruixue Xu, Qian An, Jiuhong Li, Tianhua Xu
Cutaneous dirt-adherent disease (CDAD) is a rare psychogenic dermatosis mainly occurring in young Japanese and Chinese women. It mainly occurs on cheeks, forehead, nipple, mammary areola and around mammary areola. To our knowledge, this is the first case of CDAD with the skin lesion of psoriasis rupioides to be reported. In our case, the patient, a 43-year-old Chinese man presented with thick, yellowish-brown adherent crusts on his face with severe painful of 6 days' duration. Histopathologic image: Parakeratosis, the epidermis demonstrates regular acanthosis with some thinning of the suprapapillary plates, neutrophils exocytosis are noted...
February 12, 2019: Dermatologic Therapy
https://read.qxmd.com/read/30747476/multiple-paradoxical-reactions-during-ixekizumab-therapy
#12
LETTER
Federico Pirro, Giacomo Caldarola, Clara De Simone, Gaia Moretta, Giulia Giovanardi, Ketty Peris
No abstract text is available yet for this article.
February 12, 2019: Dermatologic Therapy
https://read.qxmd.com/read/30724000/unsatisfactory-response-to-sirolimus-in-maffucci-syndrome-associated-spindle-cell-hemangiomas
#13
LETTER
Vishal Gupta, Asit Ranjan Mridha, Binod K Khaitan
No abstract text is available yet for this article.
February 5, 2019: Dermatologic Therapy
https://read.qxmd.com/read/30714265/huge-rhinophyma-in-a-complicated-patient-successfully-treated-with-c02-laser
#14
LETTER
Rocco Tortorella, Emma Mori, Miriam Rovesti, Dahiana Casanova, Roberto D'Astolto, Sara Scrivani, Mariabeatrice Bertolani, Alfredo Zucchi, Claudio Feliciani
Rhinophyma is a bothersome and disfiguring condition of the nose that is often cause of cosmetic embarrassment and social reclusion. Nowadays the therapeutic possibilities are highly variable and have to be personalized case by case. These possibilities include pharmacological therapy, laser surgery, mechanical dermabrasion and surgical excision. For patients with cardiovascular comorbidies and anticoagulant therapy, the therapeutic choice is limited. We present a case of a giant rhinophyma in a patient with several comorbidities that we successfully treated with CO2 laser...
February 3, 2019: Dermatologic Therapy
https://read.qxmd.com/read/30707471/tetra-arsenic-tetra-sulfide-ameliorates-lupus-syndromes-by-inhibiting-il-17-producing-double-negative-t-cells
#15
Yan Zhao, Zhanglei Mu, Lin Cai, Xiaojing Liu, Jia Jun, Jianzhong Zhang
Systemic lupus erythematosus (SLE) is an autoimmune disease of uncertain etiology that affects multiple tissues and organs. Tetra-arsenic tetra-sulfide (As4 S4 ), a traditional Chinese medicine, is effective on acute promyelocytic leukemia with mild side effects. In our previous study, BXSB lupus-prone mice treated with As4 S4 has showed improved monocytosis, decreased serum interleukin-6 (IL-6) and suppressed skin, liver and renal lesions with well-tolerance. In this study, we explored the effect and mechanism of As4 S4 on the MRL/lpr mice...
February 1, 2019: Dermatologic Therapy
https://read.qxmd.com/read/30697883/the-efficacy-of-omalizumab-in-cutaneous-mastocytosis-a-case-series
#16
Tiffany Hinojosa, Daniel J Lewis, Ramya Vangipuram, B A Laraib Safeer, Uyen Ngoc Mui, Christopher Haley, Sergej Konoplev, Stephen K Tyring
BACKGROUND: Mastocytosis describes a heterogeneous group of disorders arising from a clonal proliferation of mast cells. Given the lack of curative treatments for the cutaneous form, there is a significant need for superior therapies. Omalizumab is a recombinant DNA-derived humanized IgG monoclonal antibody that selectively binds to human immunoglobulin E (IgE). It represents a potential treatment for the treatment of cutaneous mastocytosis, which currently has no standard treatment. METHODS: Two patients were treated with subcutaneous omalizumab 300 mg every four weeks...
January 29, 2019: Dermatologic Therapy
https://read.qxmd.com/read/30697879/effectiveness-and-safety-of-switching-to-biosimilar-infliximab-and-etanercept-in-patients-with-psoriasis
#17
LETTER
Tamara Lund, Carsten Sand, Robert Gniadecki, Simon Francis Thomsen
Real-life data on the effectiveness and safety of biosimilar and biologic drugs licensed for treatment of psoriasis is lacking. We retrospectively analysed patient records from 69 patients with moderate to severe psoriasis treated at the department of Dermatology, Bispebjerg Hospital, Copenhagen, Denmark in the period March 1st 2015 to October 1st 2017 who were administratively switched from the anti-TNF biologics infliximab (Remicade) and etanercept (Enbrel) to the biosimilars Remsima and Benepali, respectively...
January 29, 2019: Dermatologic Therapy
https://read.qxmd.com/read/30693648/hidradenitis-suppurativa-and-botulinum-toxin-type-a-therapy-two-cases
#18
Anna Campanati, Emanuela Martina, Katia Giuliodori, Ivan Bobyr, Veronica Consales, Annamaria Offidani
Hidradenitis suppurativa is a chronic skin disease with an intense inflammatory activation. It typically affects the intertriginous areas with cysts, fistulae and scarring extremely painful. Patients suffer from severe psychological impact. HS still results in a high unmet medical need with several underdiagnosed cases, probably due to the incomplete knowledge of the pathogenesis of HS. The use of botulinum toxin a has recently been proposed as an effective therapy for HS. This article is protected by copyright...
January 28, 2019: Dermatologic Therapy
https://read.qxmd.com/read/30693647/the-analysis-of-the-therapeutic-potential-of-ustekinumab-in-psoriasis-vulgaris-treatment
#19
Dominika Wcisło-Dziadecka, Beniamin Grabarek, Celina Kruszniewska-Rajs, Barbara Strzałka-Mrozik
The molecular mechanism of ustekinumab action involves an interruption of signaling pathways activated by IL-12/23. The aim of this paper was to evaluate the efficacy of the anti-IL12/23 therapy in 7 psoriatic patients by assessing changes in the values of PASI, DLQI, BSA indexes, and an analysis of changes in the mRNA expression profile of genes IL12A, IL12B, IL23A during three 40-week long observation periods. The clinical (PASI, DLQI, BSA indexes) and molecular (RTqPCR for IL12A, IL12B, IL23A) analyses were performed on the day of ustekinumab therapy initiation, 4 weeks post first administration, and every 12 weeks thereafter...
January 28, 2019: Dermatologic Therapy
https://read.qxmd.com/read/30693634/clinical-experiences-on-alopecia-areata-treatment-with-tofacitinib-a-study-of-63-patients
#20
LETTER
Server Serdaroğlu, Burhan Engin, Uğur Çelik, Emine Erkan, Özge Aşkın, Çiğdem Oba, Zekayi Kutlubay
No abstract text is available yet for this article.
January 28, 2019: Dermatologic Therapy
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