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Respirology: Official Journal of the Asian Pacific Society of Respirology

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https://read.qxmd.com/read/30995697/does-iswt-evaluate-maximal-exercise-capacity-in-subjects-with-severe-asthma
#1
EDITORIAL
Celso R F Carvalho
No abstract text is available yet for this article.
April 17, 2019: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://read.qxmd.com/read/30989728/azithromycin-reduces-airway-inflammation-induced-by-human-rhinovirus-in-lung-allograft-recipients
#2
Kak-Ming Ling, Jessica Hillas, Melanie A Lavender, Jeremy P Wrobel, Michael Musk, Stephen M Stick, Anthony Kicic
BACKGROUND AND OBJECTIVE: Human rhinovirus (RV) is a common upper and lower respiratory pathogen in lung allograft recipients causing respiratory tract exacerbation and contributing towards allograft dysfunction and long-term lung decline. In this study, we tested the hypothesis that RV could infect both the small and large airways, resulting in significant inflammation. METHODS: Matched large and small airway epithelial cells (AEC) were obtained from five lung allograft recipients...
April 15, 2019: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://read.qxmd.com/read/30985972/what-s-in-the-cart-a-decision-rule-to-predict-short-term-mortality-during-copd-exacerbations
#3
EDITORIAL
Don D Sin
No abstract text is available yet for this article.
April 15, 2019: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://read.qxmd.com/read/30985968/emerging-respiratory-infections-threatening-public-health-in-the-asia-pacific-region-a-position-paper-of-the-asian-pacific-society-of-respirology
#4
Sunghoon Park, Ji Young Park, Yuanlin Song, Soon Hin How, Ki-Suck Jung
In past decades, we have seen several epidemics of respiratory infections from newly emerging viruses, most of which originated in animals. These emerging infections, including severe acute respiratory syndrome coronavirus (SARS-CoV), Middle East respiratory syndrome coronavirus (MERS-CoV) and the pandemic influenza A(H1N1) and avian influenza (AI) viruses, have seriously threatened global health and the economy. In particular, MERS-CoV and AI A(H7N9) are still causing infections in several areas, and some clustering of cases of A(H5N1) and A(H7N9) may imply future possible pandemics...
April 15, 2019: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://read.qxmd.com/read/30985946/associations-between-lung-and-endothelial-function-in-early-middle-age
#5
Robert J Hancox, Lathan Thomas, Michael J A Williams, Malcolm R Sears
BACKGROUND AND OBJECTIVE: Chronic lung disease is associated with impaired endothelial function and this may be a risk factor for poor cardiovascular health. It is unknown if there is an association between lung and endothelial function in the general population. We investigated associations between lung and endothelial function in a population-based cohort of 38-year-old men and women. METHODS: Systemic endothelial function was measured using peripheral arterial tonometry to calculate the Framingham reactive hyperaemia index...
April 15, 2019: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://read.qxmd.com/read/30977250/bmpr2-expressing-bone-marrow-derived-endothelial-like-progenitor-cells-alleviate-pulmonary-arterial-hypertension-in-vivo
#6
Rebecca L Harper, Suzanne Maiolo, Rebekah J Ward, Jemma Seyfang, Michaelia P Cockshell, Claudine S Bonder, Paul N Reynolds
BACKGROUND AND OBJECTIVE: Pulmonary arterial hypertension (PAH) is characterized by increased resistance in the distal pulmonary arteries, ultimately leading to right heart failure and, despite the available therapeutics, survival remains poor. Reduced expression of bone morphogenetic protein receptor type 2 (BMPR2) is strongly associated with PAH. Cell therapies are of interest in PAH, but whether this approach can upregulate BMPR2 is not known. Our objective was to evaluate a preclinical cell therapy approach based on upregulation of BMPR2...
April 12, 2019: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://read.qxmd.com/read/30977222/multidisciplinary-team-working-for-vocal-cord-dysfunction-now-it-s-go-time
#7
EDITORIAL
James H Hull
No abstract text is available yet for this article.
April 11, 2019: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://read.qxmd.com/read/30964223/hospitalizations-for-patients-with-acute-respiratory-exacerbations-in-pursuit-of-rest-or-recovery
#8
EDITORIAL
Christian R Osadnik
No abstract text is available yet for this article.
April 9, 2019: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://read.qxmd.com/read/30963672/osteopontin-lung-gene-expression-is-a-marker-of-disease-severity-in-pulmonary-arterial-hypertension
#9
Marco Mura, Matthew J Cecchini, Mariamma Joseph, John T Granton
BACKGROUND AND OBJECTIVE: Osteopontin (OPN) is a pleiotropic cytokine involved in the proliferation of pulmonary artery smooth muscle cells (PA-SMC). OPN is upregulated in the lungs of patients with pulmonary hypertension (PH) associated with pulmonary fibrosis, suggesting that the lung is a source of OPN. We hypothesized that OPN lung expression is elevated in Group I pulmonary arterial hypertension (PAH) and is correlated to haemodynamics. METHODS: Microarray analysis (Affymetrix) was performed after RNA was extracted from explanted lungs in 15 patients with Group I PAH who underwent lung transplantation (LTx) and 11 normal controls...
April 8, 2019: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://read.qxmd.com/read/30958612/letter-from-italy
#10
LETTER
Alberto Papi
No abstract text is available yet for this article.
April 8, 2019: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://read.qxmd.com/read/30945423/airway-distensibility-bringing-physiology-to-the-bedside
#11
LETTER
Andrew Wellman
No abstract text is available yet for this article.
April 3, 2019: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://read.qxmd.com/read/30945412/contemporary-concise-review-2018-asthma-and-chronic-obstructive-pulmonary-disease
#12
REVIEW
John W Upham
No abstract text is available yet for this article.
April 3, 2019: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://read.qxmd.com/read/30945371/airway-distensibility-bringing-physiology-to-the-bedside-reply
#13
LETTER
Ning-Hung Chen, Shih-Wei Lin, Li-Pang Chuang
No abstract text is available yet for this article.
April 3, 2019: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://read.qxmd.com/read/30933419/nocturnal-hypoxaemia-is-associated-with-adverse-outcomes-in-interstitial-lung-disease
#14
Lauren K Troy, Iven H Young, Edmund M T Lau, Keith K H Wong, Brendon J Yee, Paul J Torzillo, Tamera J Corte
BACKGROUND AND OBJECTIVE: Sleep-disordered breathing (SDB) has been reported as highly prevalent in idiopathic pulmonary fibrosis (IPF) and other interstitial lung disease (ILD) populations. Nocturnal oxygen desaturation (NOD), or the total sleep time spent with SpoO2 < 90% (TST < 90), can occur both with and without associated apnoeas, and is common in ILD. This study aimed to characterize abnormal SDB and extent of TST < 90 in ILD patients and evaluate relationships between TST < 90 and markers of disease severity, development of pulmonary hypertension (PH) and mortality...
April 1, 2019: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://read.qxmd.com/read/30929315/contemporary-concise-review-2018-respiratory-infections-and-tuberculosis
#15
REVIEW
David S Hui, Chi-Chiu Leung
No abstract text is available yet for this article.
March 30, 2019: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://read.qxmd.com/read/30924257/eligibility-for-anti-fibrotic-treatment-in-idiopathic-pulmonary-fibrosis-depends-on-the-predictive-equation-used-for-pulmonary-function-testing
#16
Andrew Burgess, Ken Goon, John D Brannan, John Attia, Kerrin Palazzi, Christopher Oldmeadow, Tamera J Corte, Ian Glaspole, Nicole Goh, Gregory Keir, Heather Allan, Sally Chapman, Wendy Cooper, Samantha Ellis, Peter Hopkins, Yuben Moodley, Paul Reynolds, Chris Zappala, Sacha Macansh, Christopher Grainge
BACKGROUND AND OBJECTIVE: Publicly funded therapy for idiopathic pulmonary fibrosis (IPF) relies on percentage predicted values from pulmonary function testing, for example Australian patients must have a forced vital capacity ≥50% (%FVC), transfer factor of the lung for carbon monoxide ≥ 30% (%TLco) and forced expiratory volume in 1 s (FEV1 )/FVC ratio > 0.7. Despite defined cut-off values, no jurisdiction prescribes a reference equation for use; multiple equations exist...
March 28, 2019: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://read.qxmd.com/read/30920029/air-pollution-in-the-asia-pacific-region-a-joint-asian-pacific-society-of-respirology-american-thoracic-society-perspective-republication
#17
REVIEW
Crystal M North, Mary B Rice, Thomas Ferkol, David Gozal, Christopher Hui, Soon-Hee Jung, Kozo Kuribayashi, Meredith C McCormack, Michiaki Mishima, Yasuo Morimoto, Yuanlin Song, Kevin C Wilson, Woo Jin Kim, Kwun M Fong
No abstract text is available yet for this article.
March 28, 2019: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://read.qxmd.com/read/30919511/transmission-of-bacteria-in-bronchiectasis-and-chronic-obstructive-pulmonary-disease-low-burden-of-cough-aerosols
#18
Rebecca E Stockwell, Melanie Chin, Graham R Johnson, Michelle E Wood, Laura J Sherrard, Emma Ballard, Peter O'Rourke, Kay A Ramsay, Timothy J Kidd, Nassib Jabbour, Rachel M Thomson, Luke D Knibbs, Lidia Morawska, Scott C Bell
BACKGROUND AND OBJECTIVE: Aerosol transmission of Pseudomonas aeruginosa has been suggested as a possible mode of respiratory infection spread in patients with cystic fibrosis (CF); however, whether this occurs in other suppurative lung diseases is unknown. Therefore, we aimed to determine if (i) patients with bronchiectasis (unrelated to CF) or chronic obstructive pulmonary disease (COPD) can aerosolize P. aeruginosa during coughing and (ii) if genetically indistinguishable (shared) P...
March 27, 2019: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://read.qxmd.com/read/30919491/azithromycin-and-abba-in-the-chest-clinic-the-winner-takes-it-all
#19
EDITORIAL
Peter G Gibson
No abstract text is available yet for this article.
March 27, 2019: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://read.qxmd.com/read/30912246/transbronchial-evaluation-of-peripheral-pulmonary-lesions-using-ultrasonic-spectrum-analysis-in-lung-cancer-patients
#20
Tsukasa Ishiwata, Jiro Terada, Takahiro Nakajima, Kenji Tsushima, Koichiro Tatsumi
BACKGROUND AND OBJECTIVE: Analysis of the endobronchial ultrasound (EBUS) radiofrequency spectrum has been used for convex-probe EBUS technology. Quantitative imaging analysis is also warranted for guided bronchoscopy using radial-probe EBUS (RP-EBUS) targeting peripheral pulmonary lesions (PPL). This study aimed to determine the feasibility of radiofrequency spectrum analysis for distinguishing malignant and benign PPL during diagnostic bronchoscopy. METHODS: Raw RP-EBUS images with radiofrequency data, including backscatter signals, were prospectively recorded...
March 25, 2019: Respirology: Official Journal of the Asian Pacific Society of Respirology
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