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Journals Allergology International : Of...

Allergology International : Official Journal of the Japanese Society of Allergology

https://read.qxmd.com/read/37633774/relationship-between-aspergillus-and-asthma
#21
REVIEW
Ritesh Agarwal, Valliappan Muthu, Inderpaul Singh Sehgal
Fungal sensitization is highly prevalent in severe asthma. The relationship between fungus and asthma, especially Aspergillus fumigatus, has been the subject of extensive research. The ubiquitous presence of A. fumigatus, its thermotolerant nature, the respirable size of its conidia, and its ability to produce potent allergens are pivotal in worsening asthma control. Due to the diverse clinical manifestations of fungal asthma and the lack of specific biomarkers, its diagnosis remains intricate. Diagnosing fungal asthma requires carefully assessing the patient's clinical history, immunological tests, and imaging...
August 24, 2023: Allergology International: Official Journal of the Japanese Society of Allergology
https://read.qxmd.com/read/37612167/effects-of-raw-seafood-on-the-risk-of-hypersensitivity-reaction-recurrence-in-patients-with-an-anisakis-allergy-a-retrospective-observational-study-in-japan
#22
LETTER
Yuto Hamada, Eiji Nakatani, Kentaro Watai, Maki Iwata, Yuto Nakamura, Kai Ryu, Yosuke Kamide, Kiyoshi Sekiya, Yuma Fukutomi
No abstract text is available yet for this article.
August 21, 2023: Allergology International: Official Journal of the Japanese Society of Allergology
https://read.qxmd.com/read/37607853/cyp27a1-27-hydroxycholesterol-axis-in-the-respiratory-system-contributes-to-house-dust-mite-induced-allergic-airway-inflammation
#23
JOURNAL ARTICLE
Tatsunori Ito, Tomohiro Ichikawa, Mitsuhiro Yamada, Yuichiro Hashimoto, Naoya Fujino, Tadahisa Numakura, Yusaku Sasaki, Ayumi Suzuki, Katsuya Takita, Hirohito Sano, Yorihiko Kyogoku, Takuya Saito, Akira Koarai, Tsutomu Tamada, Hisatoshi Sugiura
BACKGROUND: 27-Hydroxycholesterol (27-HC) derived from sterol 27-hydroxylase (CYP27A1) has pro-inflammatory biological activity and is associated with oxidative stress and chronic inflammation in COPD. However, the role of regulation of CYP27A1- 27-HC axis in asthma is unclear. This study aimed to elucidate the contribution of the axis to the pathophysiology of asthma. METHODS: House dust mite (HDM) extract was intranasally administered to C57BL/6 mice and the expression of CYP27A1 in the airways was analyzed by immunostaining...
August 20, 2023: Allergology International: Official Journal of the Japanese Society of Allergology
https://read.qxmd.com/read/37598072/fibrin-and-fibrinogen-degradation-products-d-dimer-ratio-can-be-a-useful-marker-for-differentiating-an-acute-attack-of-hereditary-angioedema-from-thrombotic-conditions
#24
LETTER
Daisuke Honda, Isao Ohsawa, Toshiyuki Miyata, Masayuki Ozaki, Masashi Aizawa, Yasuhiko Tomino, Katsuhiko Asanuma
No abstract text is available yet for this article.
August 17, 2023: Allergology International: Official Journal of the Japanese Society of Allergology
https://read.qxmd.com/read/37567833/potential-of-mait-cells-to-modulate-asthma
#25
REVIEW
Yasuo Shimizu, Chie Sugimoto, Hiroshi Wakao
Despite recent advances in asthma treatments, the search for novel therapies remains necessary because there are still patients with recurrent asthma exacerbations and poor responses to the existing treatments. Since group 2 innate lymphoid cells (ILC2) play a pivotal role in asthma by triggering and exacerbating type 2 inflammation, controlling ILC2s function is key to combating severe asthma. Mucosal-associated invariant T (MAIT) cells are innate-like T cells abundant in humans and are activated both in a T cell receptor-dependent and -independent manner...
August 9, 2023: Allergology International: Official Journal of the Japanese Society of Allergology
https://read.qxmd.com/read/37567832/lipocalin-2-promotes-neutrophilic-inflammation-in-nasal-polyps-and-its-value-as-biomarker
#26
JOURNAL ARTICLE
Chen Zhang, Huan Wang, Li Hu, Qianqian Zhang, Jiani Chen, Le Shi, Xiaole Song, Juan Liu, Kai Xue, Jingjing Wang, Dehui Wang, Xicai Sun
BACKGROUND: Chronic rhinosinusitis with nasal polyps (CRSwNP) is a common chronic inflammatory disease of the nasal cavity and paranasal sinuses. The role of neutrophils in the pathogenesis of CRSwNP has attracted more attention in recent years, due to its association with more severe disease and reduced steroid responsiveness. Lipocalin-2 (LCN2) has been found to modulate neutrophils infiltration in other neutrophilic inflammation including inflammatory bowel disease, rheumatoid arthritis, and psoriasis...
August 9, 2023: Allergology International: Official Journal of the Japanese Society of Allergology
https://read.qxmd.com/read/37544850/association-of-allergic-disease-with-parkinson-s-disease-a-nationally-representative-retrospective-cohort-study
#27
JOURNAL ARTICLE
Ji Yoon Nam, Sun Jae Park, Jihun Song, Seogsong Jeong, Seulggie Choi, Sang Min Park
BACKGROUND: The association of allergic diseases such as allergic rhinitis, asthma, and atopic dermatitis with Parkinson's disease (PD) risk is yet unclear. In the few preceding studies, a short follow-up duration was followed for a relatively small study population, and lifestyle behaviors were not adjusted for. Therefore, there is a need for large-scale observation studies on the association of allergic disease with PD risk after considering lifestyle behaviors. METHODS: The study population consisted of 398,936 participants aged 40 years or older who underwent health screening before 1 January 2005 from the Korean National Health Insurance Service database...
August 5, 2023: Allergology International: Official Journal of the Japanese Society of Allergology
https://read.qxmd.com/read/37482531/detrimental-impact-of-the-il-33-st2-axis-in-an-animal-infection-model-with-cryptococcus-neoformans
#28
REVIEW
Keigo Ueno, Yoshitsugu Miyazaki
Cryptococcus neoformans and Cryptococcus gattii are pathogenic fungi that infect the human respiratory system and cause life-threatening pulmonary cryptococcosis. The immunopathology of cryptococcosis is completely different from that of other fungal allergies. In murine cryptococcal infection models, cryptococcal cells are usually injected via nasal or intratracheal routes. After the infection, the alveolar epithelial cells are impaired and release IL-33, an IL-1 family cytokine that functions as an alarmin...
July 21, 2023: Allergology International: Official Journal of the Japanese Society of Allergology
https://read.qxmd.com/read/37474441/effects-of-subcutaneous-allergen-immunotherapy-on-non-targeted-allergen-induced-immune-responses
#29
LETTER
Kazuyuki Nakagome, Tomoyuki Soma, Takahiro Uchida, Ryu Sekiya, Takehito Kobayashi, Kazuki Katayama, Hidetoshi Iemura, Erika Naito, Yuki Hoshino, Sachiko Miyauchi, Yoshitaka Uchida, Yuki Shiko, Makoto Nagata
No abstract text is available yet for this article.
July 18, 2023: Allergology International: Official Journal of the Japanese Society of Allergology
https://read.qxmd.com/read/37455165/risk-factors-for-allergy-documentation-in-electronic-health-record-a-retrospective-study-in-a-tertiary-health-center-in-switzerland
#30
JOURNAL ARTICLE
Maxime Ringwald, Laura Moi, Alexandre Wetzel, Denis Comte, Yannick D Muller, Camillo Ribi
BACKGROUND: Most hospitals use electronic health records (EHR) to warn health care professionals of drug hypersensitivity (DH) and other allergies. Indiscriminate recording of patient self-reported allergies may bloat the alert system, leading to unjustified avoidances and increases in health costs. The aim of our study was to analyze hypersensitivities documented in EHR of patients at Lausanne University Hospital (CHUV). METHODS: We conducted a retrospective study on patients admitted at least 24 h to CHUV between 2011 and 2021...
July 14, 2023: Allergology International: Official Journal of the Japanese Society of Allergology
https://read.qxmd.com/read/37442743/allergic-fungal-rhinosinusitis-what-we-can-learn-from-allergic-bronchopulmonary-mycosis
#31
REVIEW
Tsuguhisa Nakayama, Jun Miyata, Natsuki Inoue, Shigeharu Ueki
Allergic fungal rhinosinusitis (AFRS) and allergic bronchopulmonary mycosis (ABPM) are inflammatory disorders of the respiratory tract resulting from type 1 and 3 hypersensitivity reactions against fungi. The hallmark features of both diseases are eosinophil infiltration into the airway mucosa caused by localized type 2 inflammation and concomitant viscid secretions in the airways. Eosinophilic mucin-induced compression of adjacent anatomic structures leads to bone erosion and central bronchiectasis in the upper and lower respiratory tracts, respectively...
July 11, 2023: Allergology International: Official Journal of the Japanese Society of Allergology
https://read.qxmd.com/read/37364966/current-topics-on-urticaria-and-urticaria-related-diseases-introduced-in-the-japanese-urticaria-clinical-practice-guidelines
#32
EDITORIAL
Naotomo Kambe
No abstract text is available yet for this article.
July 2023: Allergology International: Official Journal of the Japanese Society of Allergology
https://read.qxmd.com/read/37221123/urticaria-and-basophils
#33
REVIEW
Sarbjit S Saini
Chronic spontaneous urticaria (CSU) is a common skin disease without an etiology in the vast majority of cases. The similarity of symptoms and pathology to allergen-induced skin reactions supports that skin mast cell IgE receptor activation is also involved in CSU. Accumulating evidence also supports a role for blood basophils in disease expression. Blood basopenia is noted in active CSU disease with the recruitment of blood basophils to skin lesion sites. Blood basophils further display altered IgE receptor mediated degranulation patterns in two phenotypes that improve in remission...
July 2023: Allergology International: Official Journal of the Japanese Society of Allergology
https://read.qxmd.com/read/37210251/chronic-urticaria-and-the-pathogenic-role-of-mast-cells
#34
REVIEW
Daniel Elieh-Ali-Komi, Martin Metz, Pavel Kolkhir, Emek Kocatürk, Jörg Scheffel, Stefan Frischbutter, Dorothea Terhorst-Molawi, Lena Fox, Marcus Maurer
The signs and symptoms of chronic urticaria (CU) are caused by the activation and degranulation of skin mast cells (MCs). Recent studies have added to our understanding of how and why skin MCs are involved and different in CU. Also, novel and relevant mechanisms of MC activation in CU have been identified and characterized. Finally, the use of MC-targeted and MC mediator-specific treatments has helped to better define the role of the skin environment, the contribution of specific MC mediators, and the relevance of MC crosstalk with other cells in the pathogenesis of CU...
July 2023: Allergology International: Official Journal of the Japanese Society of Allergology
https://read.qxmd.com/read/37393135/association-of-walnut-proteins-in-household-dust-with-household-walnut-consumption-and-jug-r-1-sensitization
#35
LETTER
Hiroki Yasudo, Kiwako Yamamoto-Hanada, Masayuki Mikuriya, Fumitoshi Ogino, Tatsuki Fukuie, Yukihiro Ohya
No abstract text is available yet for this article.
June 29, 2023: Allergology International: Official Journal of the Japanese Society of Allergology
https://read.qxmd.com/read/37365039/contribution-of-monocyte-and-macrophage-extracellular-traps-to-neutrophilic-airway-inflammation-in-severe-asthma
#36
JOURNAL ARTICLE
Quang Luu Quoc, Thi Bich Tra Cao, Ji-Young Moon, Jae-Hyuk Jang, Yoo Seob Shin, Youngwoo Choi, Min Sook Ryu, Hae-Sim Park
BACKGROUND: Increased blood/sputum neutrophil counts are related to poor clinical outcomes of severe asthma (SA), where we hypothesized that classical monocytes (CMs)/CM-derived macrophages (Mφ) are involved. We aimed to elucidate the mechanisms of how CMs/Mφ induce the activation of neutrophils/innate lymphoid cells (ILCs) in SA. METHODS: Serum levels of monocyte chemoattractant protein-1 (MCP-1) and soluble suppression of tumorigenicity 2 (sST2) were measured from 39 patients with SA and 98 those with nonsevere asthma (NSA)...
June 24, 2023: Allergology International: Official Journal of the Japanese Society of Allergology
https://read.qxmd.com/read/37349231/single-cell-rna-sequencing-of-peripheral-blood-mononuclear-cells-from-kimura-disease-patient-successfully-treated-with-dupilumab
#37
LETTER
Kensuke Suga, Masahiro Kiuchi, Takahiro Kageyama, Kota Kokubo, Shigeru Tanaka, Arifumi Iwata, Kotaro Suzuki, Kiyoshi Hirahara, Hiroshi Nakajima
No abstract text is available yet for this article.
June 20, 2023: Allergology International: Official Journal of the Japanese Society of Allergology
https://read.qxmd.com/read/37336695/pretreatment-circulating-mait-cells-neutrophils-and-periostin-predicted-the-real-world-response-after-1-year-mepolizumab-treatment-in-asthmatics
#38
JOURNAL ARTICLE
Hitoshi Sasano, Norihiro Harada, Sonoko Harada, Tomohito Takeshige, Yuuki Sandhu, Yuki Tanabe, Ayako Ishimori, Kei Matsuno, Tetsutaro Nagaoka, Jun Ito, Asako Chiba, Hisaya Akiba, Ryo Atsuta, Kenji Izuhara, Sachiko Miyake, Kazuhisa Takahashi
BACKGROUND: Mepolizumab treatment improves symptom control and quality of life and reduces exacerbations in patients with severe eosinophilic asthma. However, biomarkers that predict therapeutic effectiveness must be determined for use in precision medicine. Herein, we elucidated the dynamics of various parameters before and after treatment as well as patient characteristics predictive of clinical responsiveness to mepolizumab after 1-year treatment. METHODS: Twenty-seven patients with severe asthma were treated with mepolizumab for one year...
June 17, 2023: Allergology International: Official Journal of the Japanese Society of Allergology
https://read.qxmd.com/read/37270394/bronchodilator-response-using-oscillometry-to-detect-uncontrolled-asthma
#39
LETTER
Hiromasa Nakayasu, Toshihiro Shirai, Keita Hirai, Taisuke Akamatsu, Yoshihiro Kitahara
No abstract text is available yet for this article.
June 1, 2023: Allergology International: Official Journal of the Japanese Society of Allergology
https://read.qxmd.com/read/37208200/validation-of-asthma-discrimination-criteria-using-health-insurance-claims-data-in-japan-additional-proposals-for-more-specific-criteria
#40
LETTER
Yuto Hamada, Eiji Nakatani, Takayoshi Nagahama, Katsuhiko Nagai, Kisako Nagayama, Yasuhiro Tomita, Yosuke Kamide, Kiyoshi Sekiya, Masami Taniguchi, Yuma Fukutomi
No abstract text is available yet for this article.
May 17, 2023: Allergology International: Official Journal of the Japanese Society of Allergology
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