Journals Journal of Cutaneous Medicine ...

Journal of Cutaneous Medicine and Surgery
Maxwell B Sauder, Loretta Cheung, Jennifer Beecker
IMPORTANCE: Acitretin is a systemic retinoid that is used in dermatology for a variety of conditions. A well-recognized potential adverse event from acitretin is elevated transaminases, indicating acute hepatocyte damage. Less well known is the possible cholestatic injury that can occur, signaled by elevated γ-glutamyltransferase (GGT) and alkaline phosphatase (ALP). OBSERVATIONS: Our patient presented with an acute acitretin-induced hepatitis with a mixed pattern of elevated transaminases as well as GGT and ALP...
March 2015: Journal of Cutaneous Medicine and Surgery
Andrea Marchesi, Pier Camillo Parodi, Marco Brioschi, Giorgio Sileo, Matteo Marchesi, Luca Vaienti
Background:Merkel cell carcinoma (MCC) is a rare cutaneous neuroendocrine malignancy that usually grows rapidly at the head and neck. Giant forms at the lower limbs are rarely reported and usually affect patients in the eighth decade or older.Methods:We report the case of a 60-year-old man who presented with a giant MCC on his right thigh. We managed this case by applying the 2012 updated guidelines and reviewed all cases of giant MCC of the lower limbs reported in the literature.Results:At the 4-month follow-up, the patient showed complete remission...
October 1, 2013: Journal of Cutaneous Medicine and Surgery
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