journal
Journals Journal of Obstetrics and Gyna...

Journal of Obstetrics and Gynaecology Research

https://read.qxmd.com/read/38757465/pathomorphological-characteristics-of-heat-stress-in-the-experiment
#1
JOURNAL ARTICLE
Tetiana Shablii
AIM: The purpose of this research was to explore some morphological, physiological, and biochemical changes in female and fetal Wistar rats under heat stress. METHODS: The experiment involved 30 animals, including two experimental groups (pregnant and nonpregnant females) kept under heat stress at 32°C and one control group consisting of healthy individuals kept in standard vivarium conditions. After dissection, fixation, dehydration, and primary processing, tissue samples were embedded in a mixture of paraffin and lanolin to obtain material for sections...
May 17, 2024: Journal of Obstetrics and Gynaecology Research
https://read.qxmd.com/read/38757238/evaluation-of-the-protective-effect-of-coenzyme-q10-against-x-ray-irradiation-induced-ovarian-injury
#2
JOURNAL ARTICLE
Yesim Bayoglu Tekin, Levent Tumkaya, Tolga Mercantepe, Zehra Suzan Topal, Tuğba Celik Samanci, Hulya Kilic Yilmaz, Sema Rakici, Atilla Topcu
AIM: This study focused on the anti-oxidant and anti-apoptotic effects of CoQ10 in ovaries exposed to pelvic radiation. METHODS: Thirty-two female rats were randomly assigned into four groups. Group I (control group), Group II: Only 2 Gy pelvic x-ray irradiation (IR) was administered as a single fractioned dose. Group III: 30 mg/kg CoQ10 was administered by oral gavage +2 Gy pelvic IR. Group IV: 150 mg/kg CoQ10 was administered by oral gavage +2 Gy pelvic IR...
May 16, 2024: Journal of Obstetrics and Gynaecology Research
https://read.qxmd.com/read/38747123/congenital-metastatic-neuroblastoma-with-placental-involvement-as-a-rare-cause-of-non-immune-fetal-hydrops
#3
Marta Campillo-Ajenjo, Eva Manuela Pena-Burgos, Beatriz Herrero Ruiz, Guillermo Escuer Albero, Pedro Rubio Aparicio, Manuel Parrón Pajares, Montserrat Bret Zurita, Rita María Regojo-Zapata, José Luis Bartha Rasero, Eugenia Antolín Alvarado
Non-immune hydrops fetalis represents the end-stage status of a variety of diseases, including metastatic tumors. We report a case of non-immune hydrops fetalis associated with multiple disseminated echogenic nodular lesions detected by ultrasound and confirmed by magnetic resonance. Cordocentesis demonstrated anemia and thrombopenia. Differential diagnosis included histiocytosis X, acute leukemia or metastatic disease. A stillbirth was diagnosed at week 25 + 6. The autopsy revealed hydrops fetalis, a right adrenal gland mass, multiple disseminated nodules histologically composed of small round blue cells positive for synaptophysin, and placental involvement, concordant findings with congenital undifferentiated neuroblastoma Stage M...
May 15, 2024: Journal of Obstetrics and Gynaecology Research
https://read.qxmd.com/read/38747076/re-letters-generated-by-chatgpt-author-who
#4
LETTER
Hinpetch Daungsupawong, Viroj Wiwanitkit
No abstract text is available yet for this article.
May 15, 2024: Journal of Obstetrics and Gynaecology Research
https://read.qxmd.com/read/38746986/response-to-re-letters-generated-by-chatgpt-author-who
#5
LETTER
Shigeki Matsubara
No abstract text is available yet for this article.
May 15, 2024: Journal of Obstetrics and Gynaecology Research
https://read.qxmd.com/read/38744429/letter-to-relationship-between-maternal-mortality-and-ritodrine-hydrochloride-as-a-tocolytic-agent-in-japan
#6
LETTER
Shigeki Matsubara
No abstract text is available yet for this article.
May 14, 2024: Journal of Obstetrics and Gynaecology Research
https://read.qxmd.com/read/38742699/olaparib-maintenance-therapy-for-platinum-sensitive-relapsed-ovarian-cancer-at-a-single-institution-a-retrospective-study
#7
JOURNAL ARTICLE
Takahiro Katsuda, Shin Nishio, Shingo Tasaki, Jongmyung Park, Kazuto Tasaki, Naotake Tsuda, Kimio Ushijima
AIM: In this study, we aimed to investigate patient characteristics, efficacy, prognostic factors, and safety of olaparib maintenance therapy for platinum-sensitive recurrent ovarian cancer at our institution. METHODS: Patients responding to platinum-based therapy and starting olaparib maintenance therapy for recurrent epithelial ovarian, fallopian tube, or peritoneal cancer at Kurume University Hospital between January 2018 and November 2021 were enrolled in the study...
May 14, 2024: Journal of Obstetrics and Gynaecology Research
https://read.qxmd.com/read/38720638/pregnancy-associated-atypical-hemolytic-uremic-syndrome-case-report
#8
Christopher Barrera-Hoffmann, Yadira Mariaca-Ortíz, Josué Giovani Ruiz-Villa, Lesllie Eugenia Cuevas-Cruz, María Del Rosario López-Mendoza, Jesús Carlos Briones-Garduño
Pregnancy-associated atypical hemolytic uremic syndrome (P-aHUS) is a rare disease. There are only few reports in the literature, and most are in the puerperium period. It is a thrombotic microangiopathy (TMA) characterized for microangiopathic hemolytic anemia, thrombocytopenia, and renal dysfunction. We report the case of a pregnant patient at 26.3 gestation weeks, who developed clinical features of TMA, neurological alterations, and septic shock; then after fetus and placental delivery, no clinical improvement was observed; a diagnostic protocol was performed due to suspicion of P-aHUS, showing improvement after the plasma exchange sessions and eculizumab...
May 9, 2024: Journal of Obstetrics and Gynaecology Research
https://read.qxmd.com/read/38711243/a-rare-case-of-extraluminal-interstitial-pregnancy-treated-with-laparoscopic-cornuotomy
#9
Hiroki Kurosawa, Tadashi Watanabe, Naoto Sato, Yuma Muraoka, Yukiko Matsuzawa, Yoh Watanabe
We report an extremely rare case of an extraluminal interstitial pregnancy. A 36-year-old nulliparous woman visited our hospital during the fifth week of gestation. Although no intrauterine gestational sac (GS) was identified, transabdominal ultrasonography revealed a GS-like cyst was detected in the right uterine horn. She underwent laparoscopic surgery for a suspected interstitial ectopic pregnancy. After laparoscopic cornuotomy, dye leakage was observed from the fimbria rather than the incision site. Finally, the patient was diagnosed with a right extraluminal interstitial pregnancy...
May 6, 2024: Journal of Obstetrics and Gynaecology Research
https://read.qxmd.com/read/38710649/development-and-validation-of-a-nomogram-for-predicting-specific-mortality-risk-a-study-of-competing-risk-model-based-on-real-endometrial-cancer-patients
#10
JOURNAL ARTICLE
Lin Qi, Manyin Zhao, Wenshu Li, Nan Mu, Yukun Yang, Zhaojie Yang, Aimin Lin
OBJECTIVE: This study aimed to construct a competing risk prediction model for predicting specific mortality risks in endometrial cancer patients from the SEER database based on their demographic characteristics and tumor information. METHODS: We collected relevant clinical data on patients with histologically confirmed endometrial cancer in the SEER database between 2010 and 2015. Univariate and multivariate competing risk models were used to analyze the risk factors for endometrial cancer-specific death, and a predictive nomogram was constructed...
May 6, 2024: Journal of Obstetrics and Gynaecology Research
https://read.qxmd.com/read/38697202/quality-of-care-measurement-for-patients-with-ovarian-cancer-in-japan
#11
JOURNAL ARTICLE
Tamaki Kakuwa, Tomone Watanabe, Mariko Niino, Akira Kawata, Toyomi Satoh, Noriomi Matsumura, Yoshihito Yokoyama, Kei Kawana, Yasuyuki Hirashima, Satoru Kyo, Masanori Yasuda, Kenichi Harano, Hiroko Machida, Hideki Tokunaga, Masanori Kaneuchi, Tsutomu Tabata, Yoichi Kobayashi, Satoru Nagase, Hidetaka Katabuchi, Mikio Mikami, Yoko Yamamoto, Ryoko Rikitake, Yuichi Ichinose, Takahiro Higashi
AIM: Quality of care is important to reduce disease progression, and improve both survival and quality of life. The Japan Society of Gynecologic Oncology has published treatment guidelines to promote standardized high-quality care for ovarian cancer in Japan. We developed quality indicators based on the guideline recommendations and used them on large datasets of health service use to examine the quality of ovarian cancer care. METHODS: A panel of experts developed the indicators using a modified Delphi method...
May 2, 2024: Journal of Obstetrics and Gynaecology Research
https://read.qxmd.com/read/38689519/machine-learning-models-for-prediction-of-postoperative-venous-thromboembolism-in-gynecological-malignant-tumor-patients
#12
JOURNAL ARTICLE
Bijuan Lin, Fang Chen, Meiying Wu, Chaojing Li, Lanzhi Lin
AIM: To identify risk factors that associated with the occurrence of venous thromboembolism (VTE) within 30 days after hysterectomy among gynecological malignant tumor patients, and to explore the value of machine learning (ML) models in VTE occurrence prediction. METHODS: A total of 1087 patients between January 2019 and January 2022 with gynecological malignant tumors were included in this single-center retrospective study and were randomly divided into the training dataset (n = 870) and the test dataset (n = 217)...
April 30, 2024: Journal of Obstetrics and Gynaecology Research
https://read.qxmd.com/read/38684171/aebp1-upregulation-contributes-to-cervical-cancer-progression-by-facilitating-cell-proliferation-migration-and-invasion
#13
JOURNAL ARTICLE
Songjun Liu, Yanpin Gu, Yin Shi, Shuqian Yu, Wu Li, Wen Lv
BACKGROUND: Aberrant expression of adipocyte enhancer-binding protein 1 (AEBP1) has been demonstrated to be involved in the tumorigenesis and progression of numerous cancers. This study was aimed to investigate the mechanism of AEBP1 in the development of cervical cancer. METHODS: The expression of AEBP1 in cervical cancer was assessed by immunohistochemistry. The function of AEBP1 on cell proliferation, migration, and invasion was determined by methyl thiazolyl tetrazolium assay, colony formation, and transwell assay...
April 29, 2024: Journal of Obstetrics and Gynaecology Research
https://read.qxmd.com/read/38679428/extraovarian-seromucinous-borderline-tumor-case-report-and-literature-review
#14
Mina Sakata, Seiji Mabuchi, Michihide Maeda, Shigenori Nagata, Junichiro Tanaka, Shoji Kamiura
Seromucinous borderline tumors (SMBT) are papillary neoplasms without invasive capabilities. Originally categorized as ovarian tumors, SMBT, being an endometriosis-related tumor, can manifest beyond the ovaries. To date, only four cases of extraovarian SMBT have been documented in literature. In this report, we present our experience with the first case of SMBT in the uterine cervix, which exhibited highly elevated CA19-9 levels. The patient, initially clinically diagnosed with cervical cancer, underwent treatment with radical hysterectomy and was later pathologically diagnosed with SMBT of the uterine cervix...
April 28, 2024: Journal of Obstetrics and Gynaecology Research
https://read.qxmd.com/read/38644543/establishment-of-a-diagnostic-model-of-endometriosis-based-on-disulfidptosis-related-genes
#15
JOURNAL ARTICLE
Hongyan Shi, Caixia Zhou, Yaoyao Zhao
OBJECTIVES: We aimed to establish a diagnostic model of endometriosis (EM) based on disulfidptosis-related genes (DRGs). MATERIALS AND METHODS: The mRNA expression data of EM were downloaded from the gene expression omnibus database and subjected to differential analysis, and co-expression analysis was performed based on 10 disulfidptosis genes to acquire DRGs. The differentially expressed DRGs were subjected to biofunctional analysis. Lasso analysis and support vector machine-recursive feature elimination (SVM-RFE) analysis were employed to extract the intersection of feature genes as biomarkers, and the diagnostic values of biomarkers for EM were evaluated based on receiver operating characteristic curves...
April 21, 2024: Journal of Obstetrics and Gynaecology Research
https://read.qxmd.com/read/38644529/a-web-based-dynamic-predictive-model-for-postoperative-nausea-and-vomiting-in-patient-receiving-gynecological-laparoscopic-surgery
#16
JOURNAL ARTICLE
Jiang Liu, Shirong Fang, Lin Cheng, Liwei Wang, Yuwen Wang, Lunan Gao, Yuxiu Liu
OBJECTIVE: The aim of this study was to develop a web-based dynamic prediction model for postoperative nausea and vomiting (PONV) in patients undergoing gynecologic laparoscopic surgery. METHODS: The patients (N = 647) undergoing gynecologic laparoscopic surgery were included in this observational study. The candidate risk-factors related to PONV were included through literature search. Lasso regression was utilized to screen candidate risk-factors, and the variables with statistical significance were selected in multivariable logistic model building...
April 21, 2024: Journal of Obstetrics and Gynaecology Research
https://read.qxmd.com/read/38634254/therapy-related-myeloid-neoplasms-after-treatment-for-ovarian-cancer-a-retrospective-single-center-case-series
#17
JOURNAL ARTICLE
Ayumu Matsuoka, Shinichi Tate, Kyoko Nishikimi, Satoyo Otsuka, Hirokazu Usui, Shinya Tajima, Yuji Habu, Natsuko Nakamura, Rie Okuya, Eri Katayama, Makio Shozu, Yosuke Inaba, Kaori Koga
OBJECTIVE: Therapy-related myeloid neoplasms (t-MNs) are often fatal and arise as late complications of previous anticancer drug treatment. No single-center case series has examined t-MNs in epithelial ovarian cancer (EOC). METHODS: All patients with EOC treated at Chiba University Hospital between 2000 and 2021 were included. We retrospectively analyzed the characteristics, clinical course, and outcomes of patients who developed t-MNs. RESULTS: Among 895 cases with EOC, 814 cases were treated with anticancer drugs...
April 17, 2024: Journal of Obstetrics and Gynaecology Research
https://read.qxmd.com/read/38634201/successful-laparoscopic-resection-of-retroperitoneal-ectopic-pregnancy-between-the-abdominal-aorta-and-inferior-vena-cava-a-case-report
#18
Akane Mizutani, Minoru Nagashima, Yasuyuki Ohira, Takashi Mimura, Mamiko Onuki, Ryu Matsuoka, Akihiko Sekizawa, Koji Matsumoto
Retroperitoneal ectopic pregnancies are extremely rare; only a few cases having been reported. Here, we report laparoscopic removal of an asymptomatic retroperitoneal ectopic pregnancy from a 29-year-old woman who was referred to our hospital for a suspected ectopic pregnancy. Transvaginal ultrasound did not reveal a gestational sac in the uterus or pelvic cavity. However, abdominal contrast-enhanced computer tomography showed a gestational sac between the abdominal aorta and inferior vena cava. On laparoscopy, the gestational sac was confirmed to be in this retroperitoneal location and successfully removed with minimal bleeding...
April 17, 2024: Journal of Obstetrics and Gynaecology Research
https://read.qxmd.com/read/38627884/relationship-between-maternal-mortality-and-ritodrine-hydrochloride-as-a-tocolytic-agent-in-japan
#19
JOURNAL ARTICLE
Masamitsu Nakamura, Akihiko Sekizawa, Junichi Hasegawa, Masahiko Nakata, Shinji Katsuragi, Hiroaki Tanaka, Takeshi Murakoshi, Naohiro Kanayama, Isamu Ishiwata, Tomoaki Ikeda
AIM: In Japan, unlike Western countries, tocolytic agents are administered in long-term protocols to treat threatened preterm labor. Evaluating the side effects of this practice is crucial. We examined whether ritodrine hydrochloride had been administered in cases of maternal death, aiming to investigate any relationship between ritodrine administration and maternal death. METHODS: This retrospective cohort study used reports of maternal deaths from multiple institutions in Japan between 2010 and 2020...
April 16, 2024: Journal of Obstetrics and Gynaecology Research
https://read.qxmd.com/read/38627199/spatial-distribution-of-tumor-resident-macrophages-as-predictive-biomarkers-in-endometrial-cancer
#20
JOURNAL ARTICLE
Tetsuya Matsukawa, Nobuhisa Yoshikawa, Wenting Liu, Satomi Hattori, Kosuke Yoshida, Masato Yoshihara, Satoshi Tamauchi, Akira Yokoi, Kaoru Niimi, Hiroaki Kajiyama
BACKGROUND: To investigate the role of CD47 expression and its relationship with tumor-resident macrophages, specifically at the tumor margin, in patients with type II endometrial cancer. This study aims to elucidate whether CD47 could serve as a prognostic marker and to understand the dynamics between CD47 and macrophages, which could inform new therapeutic strategies. METHODS: A retrospective cohort study was conducted involving 75 patients of type II endometrial...
April 16, 2024: Journal of Obstetrics and Gynaecology Research
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