Journals International Journal of Infec...

International Journal of Infectious Diseases : IJID
Marco Del Riccio, Saverio Caini, Guglielmo Bonaccorsi, Chiara Lorini, John Paget, Koos van der Velden, Adam Meijer, Mendel Haag, Ian McGovern, Patrizio Zanobini
INTRODUCTION: The COVID-19 pandemic significantly changed respiratory viruses' epidemiology due to non-pharmaceutical interventions and possible viral interactions. This study investigates whether the circulation patterns of respiratory viruses have returned to pre-pandemic norms by comparing their peak timing and duration during the first three SARS-CoV-2 seasons to pre-pandemic times. METHODS: GISRS data from 194 countries (2014-2023) was analyzed for epidemic peak timing and duration, focusing on pre-pandemic and pandemic periods across both hemispheres and the intertropical belt...
April 16, 2024: International Journal of Infectious Diseases: IJID
Eskild Petersen, Ziad A Memish, David S Hui, Alessandra Scagliarini, Lone Simonsen, Edgar Simulundu, Jennifer Bloodgood, Lucille Blumberg, Shui- Shan Lee, Alimuddin Zumla
epidemics, avian influenza, H5N1, highly pathogenic avian influenza, HPAI.
April 15, 2024: International Journal of Infectious Diseases: IJID
Michelle L Gatton, David Smith, Cielo Pasay, Karen Anderson, Selam Mihreteab, Hugo O Valdivia, Juan F Sanchez, Khalid B Beshir, Jane Cunningham, Qin Cheng
OBJECTIVES: Accuracy of malaria rapid diagnostic tests is threatened by Plasmodium falciparum with pfhrp2/3 deletions. This study compares gene deletion prevalence determined by multiplex qPCR and conventional PCR (cPCR) using existing samples with clonality previously determined by microsatellite genotyping. METHODS: Multiplex qPCR was used to estimate prevalence of pfhrp2/3 deletions in three sets of previously collected patient samples from Eritrea and Peru. The qPCR was validated by multiplex digital PCR...
April 15, 2024: International Journal of Infectious Diseases: IJID
Nadine Glaser, Sophie Diexer, Bianca Klee, Dr Oliver Purschke, Prof Dr Med Mascha Binder, Prof Dr Med Thomas Frese, Prof Dr Med Matthias Girndt, Pd Dr Med Jessica Höll, Dr Irene Moor, Prof Dr Med Jonas Rosendahl, Prof Dr Med Michael Gekle, Prof Dr Med Daniel Sedding, Prof Dr Med Rafael Mikolajczyk, Dr Cornelia Gottschick
OBJECTIVES: In winter 2022/23 SARS-CoV-2 had developed into one of many seasonal respiratory pathogens, causing an additional burden of acute respiratory infections (ARI). While testing was still widely used, many positive tests were not reported for the official statistics. Using data from a population-based cohort, we aimed to investigate the contribution of SARS-CoV-2 to the burden of ARI. METHODS: Over 70,000 participants of the German population-based DigiHero study were invited to a questionnaire about the number and time point of ARI, and SARS-CoV-2 test results in winter 2022/23...
April 15, 2024: International Journal of Infectious Diseases: IJID
Remigius Gröning, Jonatan Walde, Clas Ahlm, Mattias Ne Forsell, Johan Normark, Johan Rasmuson
OBJECTIVES: To investigate the effectiveness of intravenous immunoglobulin (IVIG) as treatment for COVID-19 in immunocompromised patients. METHODS: This retrospective study investigated outcomes for immunocompromised, vaccine non-responsive, patients that between September 2022 and April 2023 received IVIG as treatment for COVID-19 in the region of Västerbotten, Sweden. We analyzed clinical data, viral load, and anti-SARS-CoV-2 IgG binding and neutralization levels of patient serum samples and IVIG production batches...
April 12, 2024: International Journal of Infectious Diseases: IJID
Yi Xin Liew, Aloysius Yew Leng Ho, Gee Chuan Wong, Shimin Jasmine Chung, Thuan Tong Tan, Ban Hock Tan
BACKGROUND: In Haematology, prophylaxis for Pneumocystis jirovecii pneumonia (PCP) is recommended for patients undergoing hematopoietic stem cell transplantation and in selected categories of intensive chemotherapy for hematological malignancies. Trimethoprim-sulfamethoxazole (TMP-SMX) is the recommended first-line agent, but its use is not straightforward. Inhaled pentamidine is the recommended second-line agent but aerosolized medications were discouraged during respiratory virus outbreaks, especially during the COVID-19 pandemic, in view of potential contamination risks...
April 12, 2024: International Journal of Infectious Diseases: IJID
Han Chen, Longgang Yu, Lin Wang, Jisheng Zhang, Xudong Yan, Yan Jiang
OBJECTIVES: To identify the demographic characteristics and potential risk factors of invasive fungal sinusitis (IFS) patients with COVID-19. METHODS: Web of Science, Embase, the Cochrane Library and PubMed were searched from database inception to August 2023 using the combination of medical searching heading terms "invasive fungal sinusitis" and "COVID-19" and their free words. The research protocol was registered on PROSPERO (CRD42023467175). RESULTS: 53 studies were included...
April 11, 2024: International Journal of Infectious Diseases: IJID
Alessandra Vergori, Alessandro Cozzi Lepri, Marta Chiuchiarelli, Valentina Mazzotta, Elisabetta Metafuni, Giulia Matusali, Valentina Siciliano, Jessica Paulicelli, Eleonora Alma, Agostina Siniscalchi, Simona Sica, Elisabetta Abruzzese, Massimo Fantoni, Andrea Antinori, Antonella Cingolani
INTRODUCTION: Whether pre-exposure prophylaxis (PrEP) with tixagevimab/cilgavimab 150mg/150 mg (T/C) in individuals with hematological diseases (HD) may lead to a reduced risk of Breakthrough SARS CoV2 infection/hospitalization or death in the Omicron era remains to be established. METHODS: Observational study including participants with HD who received PrEP. breakthrough infections were defined as a SARS-CoV-2 positivity by RT-PCR. The incidence of breakthrough infections (95%CI) and of breakthrough infections /hospitalization/death was calculated using the Kaplan-Meier method and as the number of breakthrough infections per 100-PYFU according to the circulating variant (VoC)...
April 11, 2024: International Journal of Infectious Diseases: IJID
Isabel A L Slurink, Sophie C M van den Houdt, Gaëtan Mertens
OBJECTIVES: Prior studies show that long COVID has a heterogeneous presentation. Whether specific risk factors are related to subclusters of long COVID remains unknown. This study aimed to determine pre-pandemic predictors of long COVID and symptom clustering. METHODS: 3022 participants of a panel representative of the Dutch population completed an online survey about long COVID symptoms. Data was merged to 2018/2019 panel data covering sociodemographic, medical, and psychosocial predictors...
April 10, 2024: International Journal of Infectious Diseases: IJID
Surasith Chaithonwongwatthana, Wassana Wijagkanalan, Nasamon Wanlapakorn, Librada Fortuna, Vilasinee Yuwaree, Chawanee Kerdsomboon, Indrajeet Kumar Poredi, Souad Mansouri, Pham Hong Thai, Yong Poovorawan
AIM/OBJECTIVE: This study investigates placental antibody transfer following recombinant pertussis vaccination in pregnancy in a real-world setting. METHODS: This post-marketing observational study recruited pregnant women vaccinated with monovalent recombinant acellular pertussis vaccine (aPgen ; n=199) or combined to tetanus-diphtheria (TdaPgen ; n=200), or Td-vaccine only (n=54). Pregnancy, delivery, and neonatal outcomes were assessed. Cord blood was collected post-delivery and pertussis toxin (PT)-IgG, filamentous hemagglutinin (FHA)-IgG and PT-neutralizing antibodies (PT-Nab) were assessed...
April 10, 2024: International Journal of Infectious Diseases: IJID
Jiafei Yu, Kai Zhang, Tianqi Chen, Ronghai Lin, Qijiang Chen, Chensong Chen, Minfeng Tong, Jianping Chen, Jianhua Yu, Yuhang Lou, Panpan Xu, Chao Zhong, Qianfeng Chen, Kangwei Sun, Liyuan Liu, Lanxin Cao, Cheng Zheng, Ping Wang, Qitao Chen, Qianqian Yang, Weiting Chen, Xiaofang Wang, Zuxi Yan, Xuefeng Zhang, Wei Cui, Lin Chen, Zhongheng Zhang, Gensheng Zhang
BACKGROUND: The course of organ dysfunction (OD) in Corona Virus Disease 2019 (COVID-19) patients is unknown. Herein, we analyse the temporal patterns of OD in intensive care unit-admitted COVID-19 patients. METHODS: Sequential organ failure assessment scores were evaluated daily within 2 weeks of admission to determine the temporal trajectory of OD using group-based multitrajectory modelling (GBMTM). RESULTS: 392 patients were enrolled with a 28-day mortality rate of 53...
April 9, 2024: International Journal of Infectious Diseases: IJID
Manpin Zhang, Chengjuan Luo, Jianmin Wang, Hua Zhu, Changying Luo, Xia Qin, Xiaohang Huang, Yuchen Lin, Jing Chen
This is a case report of a 6-year-old girl with relapsed B cell acute lymphoblastic leukemia in which adoptive cell therapy was applied successfully to treat refractory human parvovirus (HPV) B19 infection. Allogenic chimeric antigen receptor (CAR) T-cell therapy (bispecific CD19/CD22) was bridged to hematopoietic stem cell transplantation (HSCT) using a haploidentical paternal donor. However, HPV B19 DNAemia progressed and transfusion-related graft versus host disease occurred. After finding a third-party related donor with a better HLA match, haploidentical HPV B19-seropositive CD45RA+ depleted cells (16...
April 5, 2024: International Journal of Infectious Diseases: IJID
Julien Favresse, Constant Gillot, Julien Cabo, Clara David, Jean-Michel Dogné, Jonathan Douxfils
INTRODUCTION: An increase evasion of the SARS-CoV-2 virus towards vaccination strategies and natural immunity has been rapidly described notably due to mutations in the spike receptor binding domain and the N-terminal domain. MATERIAL AND METHODS: Participants of the CRO-VAX HCP study who received the bivalent booster were followed at 6 months. A pseudovirus-neutralization test was used to assess the neutralization potency of antibodies against D614G, Delta, BA...
April 5, 2024: International Journal of Infectious Diseases: IJID
Cesar P Carcamo, Carlos Velasquez, Sandra C Rocha, Arturo Centurion-Lara, Lorena Lopez-Torres, Nikhat Parveen
OBJECTIVE: Objective of this study was to explore factors and outcomes associated with gestational syphilis in Peru. METHODS: Women from the miscarriage, vaginal delivery, and C-section wards from a large maternity hospital in Lima with, or without syphilis diagnosis were enrolled and their pregnancy outcomes compared. Maternal syphilis status using maternal blood and child serostatus using cord blood were determined by rapid plasma reagin (RPR) and rapid syphilis tests (RST)...
April 5, 2024: International Journal of Infectious Diseases: IJID
Thirumalaisamy P Velavan, Wim A Fleischmann, Peter G Kremsner
Following a two-weeks trip to Kazakhstan, a 42-year-old woman presented at the emergency department in Germany with fever, headache, nausea, and neurological symptoms. An infection with Plasmodium falciparum was rapidly diagnosed. The patient was immediately treated with intravenous artesunate and transferred to an intensive care unit. The initial parasite density was as high as 30% infected erythrocytes with 845880 parasites/µL. Since Kazakhstan was declared malaria-free in 2012, molecular testing for Plasmodium has been initiated to identify a possible origin...
April 5, 2024: International Journal of Infectious Diseases: IJID
Kosuke Tamura, Reiko Shimbashi, Ayu Kasamatsu, Bin Chang, Kenji Gotoh, Yoshinari Tanabe, Koji Kuronuma, Kengo Oshima, Takaya Maruyama, Masashi Nakamatsu, Shuichi Abe, Kei Kasahara, Junichiro Nishi, Yu Arakawa, Yuki Kinjo, Motoi Suzuki, Yukihiro Akeda, Kazunori Oishi, Adult Ipd Study Group
OBJECTIVE: We aimed to investigate the impact of preceding seasonal influenza on the clinical characteristics of adult patients with invasive pneumococcal disease (IPD) in Japan. METHODS: Data for 1,722 adult patients with IPD were analyzed before (2017-2019) and during the COVID-19 pandemic (2020-2022). RESULTS: Seasonal influenza epidemic disappeared soon after the emergence of the pandemic. Compared with that before the pandemic (66.7%), we observed a lower bacteremic pneumonia proportion in patients with IPD during the pandemic (55...
April 5, 2024: International Journal of Infectious Diseases: IJID
Manuel Ponce-Alonso, Borja M Fernández-Félix, Ana Halperin, Mario Rodríguez-Domínguez, Ana M Sánchez-Díaz, Rafael Cantón, Alfonso Muriel, Javier Zamora, Rosa Del Campo
No abstract text is available yet for this article.
April 5, 2024: International Journal of Infectious Diseases: IJID
Dagfinn Lunde Markussen, Øyvind Kommedal, Siri Tandberg Knoop, Marit Helen Ebbesen, Rune Oskar Bjørneklett, Christian Ritz, Lars Heggelund, Elling Ulvestad, Sondre Serigstad, Harleen M S Grewal
OBJECTIVES: This study aimed to describe the microbial aetiology of community-acquired pneumonia (CAP) in adults admitted to a tertiary care hospital and assess the impact of syndromic polymerase chain reaction (PCR) panels on pathogen detection. METHODS: Conducted at Haukeland University Hospital, Norway, from September 2020 to April 2023, this prospective study enrolled adults with suspected CAP. We analyzed lower respiratory tract samples using both standard-of-care tests and the BIOFIRE® FILMARRAY® Pneumonia Plus Panel (FAP plus)...
April 4, 2024: International Journal of Infectious Diseases: IJID
Yusuke Ogata, Tasuku Sato, Kanji Kato, Kazuhiro Kikuchi, Kazuya Mitsuhashi, Kei Watari, Kazuma Tamiya, Akiko Goto, Hiroki Yamaguchi, Ryo Hisada
A 76-year-old woman infected with Yezo virus (YEZV) developed liver dysfunction and thrombocytopenia following a tick bite. Despite the severity of her elevated liver enzymes and reduced platelet counts, the patient's condition improved spontaneously without any specific treatment. To our knowledge, this represents the first documented case where the YEZV genome was detected simultaneously in a patient's serum and the tick (Ixodes persulcatus) that bit the patient. This dual detection not only supports the hypothesis that YEZV is a tick-borne pathogen but also underscores the importance of awareness and diagnostic readiness for emerging tick-borne diseases, particularly in regions where these ticks are prevalent...
April 3, 2024: International Journal of Infectious Diseases: IJID
Allorie T Caldwell, Toni Gabaldón, Verónica Mixão, Nancy L Wengenack, Benjamin P Westley, Ryan W Stevens
Fungemia is common in critically-ill patient populations, and is associated with a high rate of mortality, especially when caused by non-albicans Candida species. Herein, we describe a fatal case of fungemia following cardiothoracic surgery in which the organism, initially identified as Candida inconspicua, represents a novel species: Pichia alaskaensis.
April 3, 2024: International Journal of Infectious Diseases: IJID
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