Michael G Fehlings
No abstract text is available yet for this article.
June 10, 2024: Spinal Cord
Xin Wang, Chun-Gu Hong, Ran Duan, Zhi-Lin Pang, Min-Na Zhang, Hui Xie, Zheng-Zhao Liu
STUDY DESIGN: Animal studies OBJECTIVES: To evaluate the therapeutic effect of olfactory mucosa mesenchymal stem cell (OM-MSCs) transplantation in mice with spinal cord injury (SCI) and to explore the mechanism by which OM-MSCs inhibit neuroinflammation and improve SCI. SETTING: Xiangya Hospital, Central South University; Affiliated Hospital of Guangdong Medical University. METHODS: Mice (C57BL/6, female, 6-week-old) were randomly divided into sham, SCI, and SCI + OM-MSC groups...
June 7, 2024: Spinal Cord
Qunya Qi, Ling Wang, Beining Yang, Yulong Jia, Yu Wang, Haotian Xin, Weimin Zheng, Xin Chen, Qian Chen, Fang Li, Jubao Du, Jie Lu, Nan Chen
STUDY DESIGN: Cross-sectional study. OBJECTIVES: To study the relationship between the structural changes in the cervical spinal cord (C2/3 level) and the sensorimotor function of children with traumatic thoracolumbar spinal cord injury (TLSCI) and to discover objective imaging biomarkers to evaluate its functional status. SETTING: Xuanwu Hospital, Capital Medical University, China; Beijing Key Laboratory of Magnetic Resonance Imaging and Brain Informatics, China...
June 1, 2024: Spinal Cord
Arrani Senthinathan, Mina Tadrous, Swaleh Hussain, Sandra McKay, Rahim Moineddin, Cherry Chu, Susan B Jaglal, John Shepherd, Lauren Cadel, Vanessa K Noonan, B Catharine Craven, Karen Tu, Sara J T Guilcher
STUDY DESIGN: Descriptive repeated-cross sectional retrospective longitudinal cohort study. OBJECTIVE: To investigate the impact of the COVID-19 pandemic on homecare services in individuals with traumatic or non-traumatic Spinal Cord Injury (SCI). SETTING: Health administrative database in Ontario, Canada. METHODS: A repeated cross-sectional study using linked health administrative databases from March 2015 to June 2022...
May 29, 2024: Spinal Cord
Samantha J Borg, David N Borg, Mohit Arora, James W Middleton, Ruth Marshall, Andrew Nunn, Timothy Geraghty
STUDY DESIGN: Cross-sectional survey. OBJECTIVES: Appropriate and timely lifelong access to healthcare following a spinal cord injury (SCI) is critical, yet unmet healthcare needs in this population are common. Poor experiences with healthcare providers can be a barrier to health-seeking behaviour, and we hypothesised that there would be an association between unmet healthcare needs and care experiences. This study aimed to: (1) describe healthcare provider utilisation in the past year, unmet care needs and satisfaction with healthcare services; (2) explore the association between experiences with healthcare providers and unmet healthcare needs; and (3) explore the association between healthcare provider utilisation and participant characteristics, including unmet healthcare needs...
May 28, 2024: Spinal Cord
Peter Francis Raguindin, Oche Adam Itodo, Inge Eriks-Hoogland, Taulant Muka, Mirjam Brach, Gerold Stucki, Jivko Stoyanov, Marija Glisic
STUDY DESIGN: Longitudinal study. OBJECTIVE: To explore whether individuals with traumatic spinal cord injury (TSCI) and non-traumatic SCI (NTSCI) experience different trajectories in changes of cardiometabolic disease (CMD) factors during initial rehabilitation stay. SETTING: Multicenter Swiss Spinal Cord Injury Cohort (SwiSCI) study. METHODS: Individuals without history of cardiovascular diseases were included. CMD factors and Framingham risk score (FRS) were compared between TSCI and NTSCI...
May 15, 2024: Spinal Cord
Sanna-Mari Saarimäki, Paula Reiterä, Anni Täckman, Jari Arokoski, Aki Vainionpää, Mauri Kallinen, Susanna Tallqvist, Eerika Koskinen, Harri Hämäläinen, Anna-Maija Kauppila, Heidi Anttila, Sinikka Hiekkala
STUDY DESIGN: Cross-sectional survey of the Finnish population with spinal cord injury (SCI). OBJECTIVES: To explore the frequencies of perceived environmental barriers (EB) that made participation harder for the Finnish population with SCI and to compare the occurrence of perceived EBs by gender, age, time since injury, and injury severity. SETTING: Participants were recruited from the registers of the three SCI outpatient clinics responsible for the lifelong care of people with SCI in Finland...
April 23, 2024: Spinal Cord
Sonja de Groot, Jacinthe J E Adriaansen, Janneke M Stolwijk-Swüste, Rutger Osterthun, Rita J G van den Berg-Emons, Marcel W M Post
STUDY DESIGN: Secondary analysis of cross-sectional data from the ALLRISC cohort study. OBJECTIVES: To investigate the prevalence of obesity and its association with time since injury (TSI) and physical activity (PA) in wheelchair users with long-standing (TSI > 10 years) spinal cord injury (SCI). SETTING: Community, The Netherlands. METHODS: Wheelchair users with SCI (N = 282) in TSI strata (10-19, 20-29, and ≥30 years) and divided in meeting SCI-specific exercise guidelines or not...
April 22, 2024: Spinal Cord
Elliot J Roth, Linda Lovell, Alexander Barry
STUDY DESIGN: Qualitative Cohort Study. OBJECTIVES: Many people with long-term spinal cord injury (SCI) develop adaptation strategies to succeed. Understanding the factors that support their capacity to adapt and develop is important to enhance quality of life of others with SCI. This study aims to learn how these factors influence how people with SCI attain and maintain optimal quality of life as time since injury grows. SETTING: IL, USA...
April 22, 2024: Spinal Cord
Saeed Vaheb, Yousef Mokary, Hamed Ghoshouni, Omid Mirmosayyeb, Elham Moases Ghaffary, Vahid Shaygannejad, Mohammad Yazdan Panah
STUDY DESIGN: Systematic review and meta-analysis. OBJECTIVES: The current study aimed to assess the efficacy and safety of Onabotulinum toxin A (OBTX-A) treatment for neurogenic detrusor overactivity (NDO) in spinal cord injury (SCI) patients. SETTING: Iran. METHODS: All relevant articles of clinical trials and cohort studies indexed in PubMed/MEDLINE, Embase, Scopus, and Web of Science databases up to September 6, 2022, that addressed OBTX-A treatment for NDO following SCI were included...
April 18, 2024: Spinal Cord
Marc Hohenhaus, Jan-Helge Klingler, Christoph Scholz, Ralf Watzlawick, Ulrich Hubbe, Jürgen Beck, Marco Reisert, Urs Würtemberger, Nico Kremers, Katharina Wolf
DESIGN: Prospective diagnostic study. OBJECTIVES: Anatomical evaluation and graduation of the severity of spinal stenosis is essential in degenerative cervical spine disease. In clinical practice, this is subjectively categorized on cervical MRI lacking an objective and reliable classification. We implemented a fully-automated quantification of spinal canal compromise through 3D T2-weighted MRI segmentation. SETTING: Medical Center - University of Freiburg, Germany...
April 16, 2024: Spinal Cord
Ana Clara Portela Hara, Nicole C Aching, Lucas M Marques, Sara P Barbosa, Daniel R Souza, Felipe Fregni, Linamara R Battistella, Marcel Simis
STUDY DESIGN: Using a cross-sectional design, we extracted sociodemographic and clinical data from 488 Spinal Cord Injury (SCI) patients during their initial assessment before receiving intensive rehabilitation treatment. OBJECTIVES: The primary objectives of this study were to ascertain the prevalence of cognitive impairment in the study sample and specify the key clinical and demographic predictors of cognitive functioning in SCI patients. SETTING: Lucy Montoro Rehabilitation Institute (LMRI), University of Sao Paulo, Sao Paulo, Brazil...
April 12, 2024: Spinal Cord
Kathryn Burns, Ryan Solinsky
STUDY DESIGN: Cross-sectional study. OBJECTIVES: Determine how well common clinical assessments of level and completeness of injury are correlated with symptoms of autonomic blood pressure instability and secondary medical complications after spinal cord injury (SCI). SETTING: Academic medical center, United States. METHODS: Eighty-two individuals with (n = 48) and without (n = 34) SCI had symptoms of autonomic blood pressure instability quantified with the Autonomic Dysfunction Following SCI (ADFSCI) survey...
April 12, 2024: Spinal Cord
Ahmad M S Ali, Mohammad A Mustafa, Omar M E Ali, Conor S Gillespie, George M Richardson, Simon Clark, Martin J Wilby, Christopher P Millward, Nisaharan Srikandarajah
STUDY DESIGN: Systematic review. OBJECTIVES: Primary Spinal Intradural Tumours (PSITs) are rare pathologies that can significantly impact quality of life. This study aimed to review patient reported outcomes (PROs) in PSITs. METHODS: A systematic search of Pubmed and Embase was performed to identify studies measuring PROs in adults with PSITs. PRO results were categorised as relating to Global, Physical, Social, or Mental health. Outcomes were summarised descriptively...
April 8, 2024: Spinal Cord
Chandrasekaran Jayaraman, Chaithanya Krishna Mummidisetty, Arun Jayaraman, Kimberly Pfleeger, Michelle Jacobson, Melissa Ceruolo, Ellora Sen-Gupta, James Caccese, David Chen
STUDY DESIGN: Non-interventional, cross-sectional pilot study. OBJECTIVES: To establish the validity and reliability of the BioStamp nPoint biosensor (Medidata Solutions, New York, NY, USA [formerly MC10, Inc.]) for measuring electromyography in individuals with cervical spinal cord injury (SCI) by comparing the surface electromyography (sEMG) metrics with the Trigno wireless electromyography system (Delsys, Natick, MA, USA). SETTING: Participants were recruited from the Shirley Ryan AbilityLab registry...
April 4, 2024: Spinal Cord
Pratchayapon Kammuang-Lue, Sintip Pattanakuhar, Maysa Sermsuk, Chaisiri Angkurawaranon
OBJECTIVE: To determine whether duration of detrusor overactivity (DO) during a cystometric study is an independent predictive factor of upper urinary tract deterioration (UUTD) in patients with traumatic spinal cord injury (TSCI). STUDY DESIGN: Retrospective cohort study. SETTING: A rehabilitation facility in Chiang Mai, Thailand. METHODS: Data were obtained from medical records of patients who underwent cystometric evaluation at 6-12 months after TSCI...
April 4, 2024: Spinal Cord
Auwal Bello Hassan, Auwal Abdullahi, Musa Sani Danazumi
No abstract text is available yet for this article.
April 3, 2024: Spinal Cord
Keira E Tranter, Joanne V Glinsky, Marsha Ben, Helen Patterson, Lynn Blecher, Jackie Chu, Lisa A Harvey
STUDY DESIGN: Interviews using the benefit-harm trade-off method and an online survey. OBJECTIVES: To determine the smallest worthwhile effect (SWE) of motor training on strength for people with spinal cord injury (SCI). SETTING: SCI units, Australia. METHODS: Forty people with recent SCI who had participated in motor training as part of their rehabilitation program (patient participants) and 37 physiotherapists (physiotherapist participants) working in SCI were recruited...
April 3, 2024: Spinal Cord
Marsha Ben, Federica Tamburella, Matteo Lorusso, Joanne V Glinsky, Keira E Tranter, Giorgio Scivoletto, Lynn Blecher, Anneliese Harris, Giovanni Galeoto, Joshua Wan, Lisa A Harvey
OBJECTIVE: To develop a self-report version of the Walking Index for Spinal Cord Injury II (WISCI II) and to test its reliability and validity. STUDY DESIGN: Psychometric study. SETTING: Spinal cord injury (SCI) rehabilitation centres in Australia and Italy. PARTICIPANTS: Eighty people with SCI were recruited from a sample of convenience. METHODS: Two self-report versions of the WISCI II were developed...
April 2, 2024: Spinal Cord
Lianjun Gao, Wei Gao, Hongwei Liu, Changbin Liu, Feng Yang, Qimin Wang, Weichao Zhao, Zhaohui Tong
STUDY DESIGN: Retrospective study. OBJECTIVES: To investigate the risk factors of tracheostomy and decannulation after cervical spinal cord injury (CSCI) and their epidemiological changes over the past 8 years in Beijing Bo'ai Hospital, China Rehabilitation Research Center (CRRC), China. SETTING: Beijing Bo'ai Hospital, CRRC. METHODS: We reviewed 8 years of patient data (2013.1.1 to 2020.12.31) at CRRC, focusing on those hospitalized and diagnosed with CSCI...
March 30, 2024: Spinal Cord
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