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Journals Medical Science Monitor : Inte...

Medical Science Monitor : International Medical Journal of Experimental and Clinical Research

https://read.qxmd.com/read/38801723/percutaneous-coronary-intervention-as-a-non-surgical-treatment-for-ischemic-mitral-regurgitation-in-patients-with-multi-vessel-coronary-artery-disease
#1
JOURNAL ARTICLE
Xiaoyan Wang, Zhihong Liu, Aoyun Rong, Bofei Ma, Ruixing Mo
BACKGROUND Multi-vessel coronary artery disease (MVD) represents a severe type of coronary artery disease (CAD). Ischemic mitral regurgitation (IMR) is a common mechanical complication in patients with CAD. This study aimed to retrospectively investigate the efficacy of percutaneous coronary intervention (PCI) on moderate/severe IMR in patients with MVD. MATERIAL AND METHODS Clinical data were collected from 15 patients who underwent successful treatment for MVD combined with moderate/severe IMR through the PCI procedure and achieved complete revascularization between January 2014 and December 2022...
May 27, 2024: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://read.qxmd.com/read/38797985/exploring-the-educational-social-and-physical-activities-among-health-care-undergraduates-a-cross-sectional-study-among-saudi-students
#2
JOURNAL ARTICLE
Alya Alghamdi, Wajid Syed, Osama A Samarkhandi, Mohammed M Albalawi, Ibrahim Nasser Alsulaihim, Shogair Mshal Almutairi, Mahmood Basil A Al-Rawi
BACKGROUND The time spent on diverse social, physical, and educational activities among healthcare undergraduates (HCUs) tremendously impacts their academic and personal lives. Therefore, this study aimed to assess the social, physical, and educational activities among HCUs at King Saud University (KSU) in Riyadh, Saudi Arabia (SA). MATERIAL AND METHODS A cross-sectional, self-prepared, and pre-tested e-questionnaire (electronic questionnaire) based study using a convenience sampling design in a university in SA from August 21 to November 21, 2023 was conducted to assess their various activities outside of classes, using a 16-item e-questionnaire to investigate time spent on social (4 items), physical (3 items), and educational activities (3 items)...
May 27, 2024: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://read.qxmd.com/read/38796697/the-influence-of-gestational-diabetes-mellitus-on-maternal-and-neonatal-outcomes-a-retrospective-study-in-rzesz%C3%A3-w-poland
#3
JOURNAL ARTICLE
Katarzyna Kalandyk-Osinko, Joanna Baran, Rafał Baran, Kamil Gierek, Anna Juza, Elżbieta Kraśnianin, Sławomir Januszek, Beata Blajer-Olszewska, Tomasz Kluz, Dorota Darmochwał-Kolarz
BACKGROUND Gestational diabetes mellitus (GDM) affects 5.8-12.9% of pregnant women, while pre-gestational diabetes mellitus (PGDM) affects 0.4-1.1%. GDM increases the risk of perinatal complications and long-term health issues. This retrospective study from a single centre in Rzeszów, Poland aimed to evaluate maternal and neonatal outcomes of pregnancy of 65 women with gestational diabetes mellitus. MATERIAL AND METHODS The study group consisted 65 women with GDM. The control group consisted 60 women without...
May 26, 2024: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://read.qxmd.com/read/38794788/comparative-efficacy-of-micro-needle-knife-therapy-and-acupuncture-in-acute-ankle-sprains-a-randomized-controlled-trial
#4
RANDOMIZED CONTROLLED TRIAL
Sen-Wei Lu, Bo-Xu Lang, Jia-Na Liu, Xiao-Xiao Ma, Tang-Tang Li, Xin Du, Mao-Liang Zhang
BACKGROUND Micro-needle knife (MNK) therapy releases the superficial fascia to alleviate pain and improve joint function in patients with acute ankle sprains (AAS). We aimed to evaluate the efficacy and safety of MNK therapy vs that of acupuncture. MATERIAL AND METHODS This blinded assessor, randomized controlled trial allocated 80 patients with AAS to 2 parallel groups in a 1: 1 ratio. The experimental group received MNK therapy; the control group underwent conventional acupuncture treatment at specified acupoints...
May 25, 2024: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://read.qxmd.com/read/38787794/enhanced-recovery-of-local-anesthesia-in-pediatric-patients-the-impact-of-photobiomodulation-on-reversing-anesthesia-effects
#5
RANDOMIZED CONTROLLED TRIAL
Aneta Olszewska, Jacek Matys, Kinga Grzech-Leśniak, Agata Czajka-Jakubowska
BACKGROUND The split-mouth study design is used in oral health research and usually consists of 2 treatments randomly assigned to either the right or left side. This split-mouth study aimed to evaluate the efficacy of photobiomodulation on reversal of local anesthesia in 50 children aged 8-10 years. MATERIAL AND METHODS The study was conducted among 50 children: 27 girls and 23 boys, aged 8-10 years (mean age 9.38±1.15 years), who presented 2 carious maxillary permanent molars. One side was randomly assigned to the laser group (50 teeth), and the contralateral side to the control group (50 teeth)...
May 24, 2024: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://read.qxmd.com/read/38783538/lipid-peroxidation-reduced-glutathione-and-glutathione-peroxidase-levels-in-intervertebral-discs-of-patients-with-lumbar-degenerative-disc-disease
#6
JOURNAL ARTICLE
Noppawan Phumala Morales, Witcharat Loahachanwanich, Ekkapoj Korwutthikulrangsri, Monchai Ruangchainikom, Werasak Sutipornpalangkul
BACKGROUND Either a reduction in antioxidant levels or an accumulation of reactive oxygen species can heighten susceptibility to oxidative damage in disc cells. To date, no research has investigated the levels of lipid peroxidation products (thiobarbituric acid reactive substances [TBARs]), reduced glutathione (GSH), and glutathione peroxidase (GPx) in excised human lumbar disc tissues affected by degenerative disease. Therefore, this study aimed to evaluate lipid peroxidation products in excised disc tissues from patients with degenerative disc disease...
May 24, 2024: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://read.qxmd.com/read/38781124/biomarkers-for-early-prediction-and-management-of-preeclampsia-a-comprehensive-review
#7
REVIEW
Julia Tomkiewicz, Dorota A Darmochwał-Kolarz
Preeclampsia is a common complication of pregnancy. It is a multi-organ disorder that remains one of the main causes of maternal morbidity and mortality. Additionally, preeclampsia leads to many complications that can occur in the fetus or newborn. Preeclampsia occurs in about 1 in 20 pregnant women. This review focuses on the prediction of preeclampsia in women, using various biomarkers, in particular, a factor combining the use of soluble FMS-like tyrosinokinase-1 (sFlt-1) and placental growth factor (PlGF)...
May 23, 2024: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://read.qxmd.com/read/38778508/mrto4-enhances-glycolysis-to-facilitate-hcc-progression-by-inhibiting-aldob
#8
JOURNAL ARTICLE
Yongyuan Zheng, Yansong Huang, Weibing Li, Hongqiu Cheng
BACKGROUND MRT4 Homolog, Ribosome Maturation Factor (MRTO4) is often upregulated in cancer cells. However, its impact in hepatocellular carcinoma (HCC) is less well understood. Herein, we explored the prognostic and energy metabolism reprogramming role of MRTO4 in HCC. MATERIAL AND METHODS Clinical data were obtained from The Cancer Genome Atlas (TCGA), and the expression of MRTO4 in clinical samples was analyzed. The association between different variables and overall survival (OS) was studied, as well as their potential as independent prognostic factors, using Cox regression analysis...
May 23, 2024: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://read.qxmd.com/read/38776271/incidence-risk-factors-and-outcomes-of-left-atrial-enlargement-in-patients-requiring-right-ventricular-pacing-a-retrospective-study-of-461-cases-from-2012-to-2020
#9
JOURNAL ARTICLE
Wei-Chieh Lee, Wei-Ting Chang, Hsiu-Yu Fang, Huang-Chung Chen, Mien-Cheng Chen, Ping-Yen Liu
BACKGROUND Long-term right ventricular (RV) pacing has been linked to left atrial enlargement (LAE). The incidence and risk factors associated with significant LAE after RV pacing remain unknown. This retrospective study included 461 patients requiring RV pacing at 2 centers between 2012 and 2020 and aimed to evaluate the incidence, risk factors, outcomes, and complications of LAE. MATERIAL AND METHODS A total of 461 patients with normal-sized pre-implant left atrial dimension and dual-chamber pacing pacemaker implantation for complete atrioventricular block were enrolled...
May 22, 2024: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://read.qxmd.com/read/38775003/retracted-md-1-deficiency-accelerates-myocardial-inflammation-and-apoptosis-in-doxorubicin-induced-cardiotoxicity-by-activating-the-tlr4-mapks-nuclear-factor-kappa-b-nf-%C3%AE%C2%BAb-signaling-pathway
#10
JOURNAL ARTICLE
Ying-Jun Zhang, He Huang, Yu Liu, Bin Kong, Guangji Wang
This publication has been retracted by the Editor due to the identification of non-original figure images and manuscript content that raise concerns regarding the credibility and originality of the study and the manuscript. Reference: Ying-Jun Zhang, He Huang, Yu Liu, Bin Kong, Guangji Wang. MD-1 Deficiency Accelerates Myocardial Inflammation and Apoptosis in Doxorubicin-Induced Cardiotoxicity by Activating the TLR4/MAPKs/Nuclear Factor kappa B (NF-kappaB) Signaling Pathway. Med Sci Monit, 2019; 25: 7898-7907...
May 22, 2024: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://read.qxmd.com/read/38773745/impact-of-patient-education-formats-on-treatment-adherence-and-denture-hygiene-in-edentulous-patients-a-comparative-study
#11
COMPARATIVE STUDY
Youssef Abdullah Algarni, Rashmi S Gupta, Lakshya Kumar, Khurshid Mattoo, Syed M Yassin, Mohammad Zahir Kota, Fawaz Abdul Hamid Baig, Mohammed Ibrahim, Suheel Manzoor Baba, Shadi Abdullah Hamzi
BACKGROUND Effective communication and patient education are important in geriatric dental care. Memory decline complicates patient adherence. This study aimed to compare verbal, audio, and video patient education material (PEM) and adherence to dental prosthetic management in edentulous patients. MATERIAL AND METHODS 90 completely/partially edentulous patients (aged 40 to 70 years), were divided (simple random) into three groups (Gp) of 30 each . A total of 68 instructions were organized into 9 learning categories...
May 22, 2024: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://read.qxmd.com/read/38771735/protective-role-of-trpc3-gene-polymorphism-rs10518289-in-obstructive-sleep-apnea-hypopnea-syndrome-among-hypertensive-patients
#12
JOURNAL ARTICLE
Yu Li, Reyihanguli Shataer, Yulan Chen, Xiaoli Zhu, Xiaojing Sun
BACKGROUND Obstructive sleep apnea-hypopnea syndrome (OSAHS) presents a significant health concern, particularly among individuals with essential hypertension (EH). Understanding the genetic underpinnings of this association is crucial for effective management and intervention. We investigated the relationship between TRPC3 gene polymorphisms and susceptibility to OSAHS in patients with EH. MATERIAL AND METHODS We enrolled 373 patients with EH hospitalized at the First Affiliated Hospital of Xinjiang Medical University between April 2015 and November 2017...
May 21, 2024: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://read.qxmd.com/read/38769717/impact-of-serum-vitamin-d-b6-and-b12-and-cognitive-functions-on-quality-of-life-in-peri-and-postmenopausal-polish-women
#13
JOURNAL ARTICLE
Dorota Raczkiewicz, Mariusz Gujski, Beata Sarecka-Hujar, Krzysztof Suski, Agnieszka Pedrycz-Wieczorska, Artur Wdowiak, Iwona Bojar
BACKGROUND Menopause initiates or accelerates health problems in a woman’s life, and affects cognitive processes and quality of life. We aimed to assess the quality of life, cognitive functions, and serum vitamin D, B6, and B12 concentrations in perimenopausal and postmenopausal Polish women. Also, we correlated the assessment of the quality of life with these vitamin concentrations and cognitive functions. MATERIAL AND METHODS The study was conducted in 287 perimenopausal and postmenopausal women...
May 21, 2024: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://read.qxmd.com/read/38768093/effect-of-individualized-peep-guided-by-driving-pressure-on-diaphragm-function-in-patients-undergoing-laparoscopic-radical-resection-of-colorectal-cancer-a-randomized-controlled-trial
#14
RANDOMIZED CONTROLLED TRIAL
Mingyue Zhang, Yongbo Yu, Cheng Qiu, Xiaoqiong Xia, Yuanming Sun, Liang Wang, Guifen Ma, Xiang Gao
BACKGROUND The concept of driving pressure (ΔP) has been established to optimize mechanical ventilation-induced lung injury. However, little is known about the specific effects of setting individualized positive end-expiratory pressure (PEEP) with driving pressure guidance on patient diaphragm function. MATERIAL AND METHODS Ninety patients were randomized into 3 groups, with PEEP set to 0 in group C; 5 cmH₂O in group F; and individualized PEEP in group I, based on esophageal manometry. Diaphragm ultrasound was performed in the supine position at 6 consecutive time points from T0-T5: diaphragm excursion, end-expiratory diaphragm thickness (Tdi-ee), and diaphragm thickening fraction (DTF) were measured...
May 20, 2024: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://read.qxmd.com/read/38764217/diagnostic-efficiency-of-acr-tirads-score-for-differentiating-benign-and-malignant-thyroid-nodules-of-various-pathological-types
#15
JOURNAL ARTICLE
Yan Xu, Jiashun Pi, Yihan Jinghu, Xiaotao Wang, Dong Xu, Jie Liu
BACKGROUND Thyroid nodule prevalence reaches 65% in the general population. Hence, appropriate ultrasonic examination is key in disease monitoring and management. We investigated the American College of Radiology Thyroid Imaging Reporting and Data System (ACR-TIRADS) score for diagnosis of benign and malignant thyroid nodules and pathological types. MATERIAL AND METHODS A retrospective study was conducted. According to ultrasound images, ultrasonic characteristics of benign and malignant thyroid nodules and different pathological types were analyzed using ACR-TIRADS score, and diagnostic value was determined...
May 20, 2024: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://read.qxmd.com/read/38762751/treatment-of-avn-induced-proximal-pole-scaphoid-nonunion-using-a-fifth-and-fourth-extensor-compartmental-artery-as-a-vascularized-pedicle-bone-graft-a-retrospective-case-series
#16
JOURNAL ARTICLE
Müjdat Adaş
BACKGROUND Scaphoid nonunion (SN) is a challenging condition in wrist pathology, often resulting in severe consequences if left untreated. Surgical intervention, particularly using vascularized bone grafts (VBGs), is a promising but uncertain approach. The 4+5 extensor compartment artery (ECA) pedicled graft, less commonly used for SN, has potential benefits due to its vascular supply and accessibility to the scaphoid. This study aimed to evaluate the effectiveness of the 4+5 ECA pedicled graft combined with headless compression screw fixation in treating avascular necrosis (AVN)-induced proximal pole SN...
May 19, 2024: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://read.qxmd.com/read/38760925/new-computerized-planning-algorithm-and-clinical-testing-of-optimized-nuss-bar-design-for-patients-with-pectus-excavatum
#17
JOURNAL ARTICLE
János György Papp, Ákos Kiss, Krisztián Balogh, László Kostyál, Imre Tóth, Tibor Gáll, Péter Vajda, Tamás F Molnár, István Papp, László Szabó, Árpád B Palotás
BACKGROUND Computer-aided design (CAD) has been used in the Nuss procedure to determine the bar length and shape. Despite computer aid, the shape and design remain quite intuitive. We tested a new algorithm to determine the optimal bar shape. MATERIAL AND METHODS The normal sterno-vertebral distance was defined on computed tomography (CT) scans of patients without pectus excavatum (PEx) at the same level where the deepest depression was found on CT scans of 97 patients with PEx. Four points were marked on the CT scan of 60 patients with PEx at the deepest deformity: P1: edge of the vertebra; P2: edge of the deformity; P3: the expected contact point of the bar and the rib; and P4: the expected end of the bar...
May 18, 2024: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://read.qxmd.com/read/38755961/impact-of-cluster-nursing-intervention-on-icu-patients-psychological-well-being-and-complications-associated-with-tracheal-intubation-and-extubation
#18
JOURNAL ARTICLE
Xuezhong Yi, Junjun Li, Yuyou Huang, Ran Liu, Zhiyuan Zhong
BACKGROUND Nurses in the Intensive Care Unit (ICU) play a critical role in recognizing patients who are at risk of deterioration by conducting continual assessments and taking suitable measures in response to changing health status. The validity of the cluster nursing intervention has been studied previously, but its use among ICU patients with tracheal intubation and extubation has not been examined. This study assessed the effectiveness of cluster nursing intervention in ICU patients with tracheal intubation and extubation...
May 17, 2024: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://read.qxmd.com/read/38751083/prevalence-and-management-of-chronic-pain-including-neuropathic-pain-in-dialysis-patients-with-end-stage-renal-disease
#19
JOURNAL ARTICLE
Klaudia Kitala-Tańska, Ewa Kania-Zimnicka, Damian Tański, Norbert Kwella, Tomasz Stompór, Małgorzata Stompór
BACKGROUND Chronic kidney disease (CKD) is a growing global health concern. Chronic pain, as a common symptom of CKD, particularly among patients with end-stage renal disease (ESRD), is influenced by complications, dialysis procedures, and comorbidities. We aimed to evaluate chronic pain and probable neuropathic pain in 96 dialysis patients with ESRD using the Douleur Neuropathique 4 (DN4) questionnaire. MATERIAL AND METHODS A total of 96 patients from a single dialysis center were enrolled for the purpose of this study...
May 16, 2024: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://read.qxmd.com/read/38745408/comparative-analysis-of-postoperative-sagittal-balance-in-expansive-open-door-laminoplasty-versus-laminectomy-with-fusion-for-multilevel-ossification-of-posterior-longitudinal-ligament-a-retrospective-study
#20
COMPARATIVE STUDY
Xudong Ma, Zhen Yu, Duoyue Wu, Yan Huang
BACKGROUND This single-center study included 80 patients with multilevel cervical ossification of the posterior longitudinal ligament (OPLL) and aimed to compare postoperative sagittal balance following treatment with expansive open-door laminoplasty (LP) vs total laminectomy with fusion (LF). MATERIAL AND METHODS Data of 80 patients with multilevel OPLL treated with LP vs LF between January 2017 and January 2022 were retrospectively analyzed. The basic data, cervical sagittal parameters, and clinical outcomes of the patients were counted in the preoperative and postoperative periods, and complications were recorded...
May 15, 2024: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
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