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Journals Journal of Infection and Chemo...

Journal of Infection and Chemotherapy : Official Journal of the Japan Society of Chemotherapy

https://read.qxmd.com/read/38782238/a-rapid-simultaneous-antigen-detection-of-haemophilus-influenzae-and-streptococcus-pneumoniae-for-predicting-the-prognosis-of-acute-otitis-media
#1
JOURNAL ARTICLE
Masamitsu Kono, Yosuke Kamide, Toshihiro Tanaka, Yoshifumi Uno, Keiko Kanesada, Chiaki Suzuki, Seiji Sawaki, Masaru Kunimoto, Chikako Kayama, Kenji Suzuki, Fumiyo Kudo, Shigenori Matsubara, Shoichi Sawada, Yukako Goto, Akihiro Uchizono, Daichi Murakami, Takuji Miyata, Norikazu Okamura, Muneki Hotomi
BACKGROUND: Rapid identification of causative bacteria in treatment of acute otitis media (AOM) is of paramount importance for appropriate antibiotic use. MATERIALS AND METHODS: This prospective observational study was conducted in 15 hospitals and clinics in Japan between 2018 and 2020. A new rapid antigen test kit (AOS-116), which simultaneously detects antigens for Streptococcus pneumoniae (Sp) and Haemophilus influenzae (Hi), was applied for middle ear fluids (MEFs) and nasopharyngeal swabs (NPSs) in patients with moderate to severe AOM...
May 21, 2024: Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy
https://read.qxmd.com/read/38782237/epidemiological-study-of-respiratory-syncytial-virus-infection-in-adults-during-the-pandemic-of-covid-19
#2
JOURNAL ARTICLE
Nobuhiro Asai, Yuichi Shibata, Atsuko Yamada, Wataru Ohashi, Mina Takayama, Yuzuka Kawamoto, Narimi Miyazaki, Daisuke Sakanashi, Tomoko Ohno, Akiko Nakamura, Isao Koita, Hiroyuki Suematsu, Sumie Chida, Toshihiro Ohta, Hideo Kato, Mao Hagihara, Jun Hirai, Nobuaki Mori, Hiroshige Mikamo
INTRODUCTION: While respiratory syncytial virus (RSV) is one of the most common pathogens in adults admitted to the ICU due to respiratory diseases, no reports regarding the occurrence rate of RSV infections in adults in Japan during the COVID-19 pandemic exist. PATIENTS AND METHODS: We conducted this retrospective study to examine the exact occurrence rate of RSV infections in adults. We reviewed all patients (>18 years) with any respiratory symptoms who received quantitative polymerase chain reaction (PCR) using nasopharyngeal samples for respiratory viruses by GeneLEAD at the Aichi Medical University Hospital between November 2022 and November 2023...
May 21, 2024: Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy
https://read.qxmd.com/read/38777152/blood-culture-bottles-for-culturing-cerebrospinal-fluid-in-cases-of-bacterial-meningitis-caused-by-enterococcus-faecalis-a-case-report-%C3%A2
#3
Shugo Inada, Keitaro Omori, Hiroki Kitagawa, Yumiko Koba, Toshihito Nomura, Norifumi Shigemoto, Akira Taguchi, Yasuyuki Kinoshita, Noboru Hattori, Hiroki Ohge
Pathogen identification is essential for the treatment of bacterial meningitis. However, cerebrospinal fluid (CSF) culture tests are often negative when antimicrobial agents are administered before CSF is collected. Therefore, it is necessary to improve the culturing process for such samples. Here, we report a case of bacterial meningitis where the causative bacteria were detected by inoculating that patient's CSF samples into blood culture bottles. A 52-year-old man developed a fever and headache after undergoing transnasal transsphenoidal surgery for a nonfunctioning pituitary neuroendocrine tumor...
May 20, 2024: Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy
https://read.qxmd.com/read/38777151/investigation-of-severe-acute-respiratory-syndrome-coronavirus-2-infection-status-in-solid-organ-transplant-recipients-treated-with-tixagevimab-cilgavimab
#4
JOURNAL ARTICLE
Ririka Aihara, Keisuke Umemura, Yoshiki Katada, Shunsaku Nakagawa, Takashi Kobayashi, Etsuro Hatano, Hiroshi Date, Miki Nagao, Tomohiro Terada
INTRODUCTION: Tixagevimab and cilgavimab (T/C) are neutralizing antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that can be used to prevent SARS-CoV-2 infection in solid organ transplant (SOT) recipients. However, their neutralizing activity against recent variants was reduced, raising concerns regarding the emergence of breakthrough coronavirus diseases 2019 (COVID-19). This study aimed to investigate the status of the COVID-19 breakthrough after T/C administration...
May 20, 2024: Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy
https://read.qxmd.com/read/38754836/hemophagocytic-lymphohistiocytosis-complicating-septicemic-melioidosis-a-case-report
#5
Sujata Devi, Arpita Dash, Anupam Dey, Susama Patra, Biswajit Sahoo, Ashoka Mahapatra, Sunita Dalei
Melioidosis is an infectious disease caused by Burkholderia pseudomallei. People infected with B. pseudomallei experience fever and skin changes, pneumonia, abscesses, and septic shock that could cause death. Hemophagocytic lymphohistiocytosis is a severe inflammatory syndrome due to the excess activation of macrophages and T cells. We report a 50-year-old hypertensive and diabetic male patient presented with high-grade intermittent fever with loss of appetite and weight loss for two months and a history of jaundice, backache and swelling of both feet for 15 days...
May 14, 2024: Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy
https://read.qxmd.com/read/38729565/retrospective-study-to-investigate-appropriate-duration-of-antibiotic-treatment-for-uncomplicated-staphylococcus-aureus-bacteremia-in-patients-with-immunodeficiency
#6
JOURNAL ARTICLE
Yuichi Shibata, Nobuhiro Asai, Jun Hirai, Nobuaki Mori, Mao Hagihara, Hiroshige Mikamo
BACKGROUND: Since the appropriate antibiotic duration for uncomplicated Staphylococcus aureus (S. aureus) bacteremia (u-SAB) in an immunocompromised state is still unclear, physicians are likely to extend antibiotic therapy from 2 weeks to 4-6 weeks. To examine the appropriate duration of antibiotic therapy for u-SAB, we performed this study. PATIENTS AND METHODS: We reviewed all patients with u-SAB at our institute seen between January 2020 and August 2023. A total of 51 patients were enrolled, and they were divided into the following two groups by antibiotic duration: longer duration group ≥ 28 days after blood culture negativity, and shorter duration group...
May 8, 2024: Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy
https://read.qxmd.com/read/38714273/japanese-society-for-infection-prevention-and-control-guide-to-clostridioides-difficile-infection-prevention-and-control
#7
JOURNAL ARTICLE
Hiroyuki Kunishima, Kaoru Ichiki, Hiroki Ohge, Fumie Sakamoto, Yuka Sato, Hiromichi Suzuki, Atsushi Nakamura, Shigeru Fujimura, Kazuaki Matsumoto, Hiroshige Mikamo, Tetsu Mizutani, Yoshitomo Morinaga, Minako Mori, Yuka Yamagishi, Sadako Yoshizawa
No abstract text is available yet for this article.
May 5, 2024: Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy
https://read.qxmd.com/read/38710470/corrigendum-to-long-term-transition-of-antibody-titers-in-healthcare-workers-following-the-first-to-fourth-doses-of-mrna-covid-19-vaccine-comparison-of-two-automated-sars-cov-2-immunoassays-journal-of-infection-and-chemotherapy-29-2023-534-538
#8
Yumi Taniguchi, Koichiro Suemori, Keiko Tanaka, Ai Okamoto, Akiko Murakami, Hitoshi Miyamoto, Yasunori Takasuka, Masakatsu Yamashita, Katsuto Takenaka
No abstract text is available yet for this article.
May 4, 2024: Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy
https://read.qxmd.com/read/38705237/efficacy-of-carbapenems-and-alternative-antimicrobials-for-treating-complicated-urinary-tract-infections-caused-by-caused-by-third-generation-cephalosporin-resistant-gram-negative-bacteria-a-systematic-review-and-meta-analysis-of-randomised-controlled-trials
#9
JOURNAL ARTICLE
Maeda Masayuki, Tomiko Sunaga, Miki Takenaka Sato, Takeshi Hasegawa, Hisashi Noma, Erika Ota
BACKGROUND: Specific data concerning the efficacy of alternative antibiotics for carbapenems against complicated urinary tract infections (cUTIs) attributed to antimicrobial-resistant (AMR) uropathogens are lacking. OBJECTIVES: This study aimed to assess the efficacy of carbapenems and non-carbapenem antibiotics in the clinical outcomes of cUTIs caused by AMR uropathogens. METHODS: In this systematic review and meta-analysis, databases, including MEDLINE/PubMed, the Cochrane Library, Embase and ClinicalTrials...
May 3, 2024: Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy
https://read.qxmd.com/read/38697390/rapid-screening-of-positive-blood-cultures-for-extended-spectrum-%C3%AE-lactamases-and-metallo-%C3%AE-lactamases-using-a-drug-susceptibility-testing-microfluidic-method
#10
JOURNAL ARTICLE
Yuka Yamagishi, Norihisa Nakayama, Akito Doke, Saya Iwame, Yoshie Nishida, Yu Arakawa, Hiroshige Mikamo
OBJECTIVES: An increasing number of drug-resistant bacteria have been identified recently. In particular, drug-resistant bacteria have been linked to unfavorable prognoses in patients with bacteremia, highlighting the need for rapid testing. Our previous studies have focused on the utility of a drug susceptibility testing microfluidic (DSTM) method using microfluidic channels. A system with this DSTM method for screening for β-lactamases can rapidly detect extended-spectrum β-lactamases (ESBLs) and metallo-β-lactamases (MBLs)...
April 30, 2024: Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy
https://read.qxmd.com/read/38679384/role-of-inflammatory-markers-in-the-assessment-of-meningitis-in-adult-patients-with-fever-and-headache
#11
JOURNAL ARTICLE
Toshihiko Takada, Kenji Yoshida, Sugihiro Hamaguchi, Shunichi Fukuhara
BACKGROUND: Meningitis, especially of bacterial origin, is a medical emergency that must be diagnosed promptly. However, due to the associated risks of complications of lumbar puncture, it is crucial to identify individuals who truly need it. The aim of this study was to assess the diagnostic role of inflammatory markers in distinguishing among patients without meningitis, those with aseptic meningitis, and those with bacterial meningitis. METHODS: This was a retrospective, diagnostic study at an acute care hospital, involving adult patients who presented to either ambulatory care or the emergency department with fever and headache, but without altered mental status or neurological deficits...
April 26, 2024: Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy
https://read.qxmd.com/read/38677389/traditional-japanese-herbal-medicine-hochuekkito-protects-development-of-sepsis-after-nasal-colonization-in-mice
#12
JOURNAL ARTICLE
Tatsuya Shiga, Masamitsu Kono, Daichi Murakami, Hideki Sakatani, Keisuke Ogura, Muneki Hotomi
INTRODUCTION: Streptococcus pneumoniae, a commensal in the nasopharynx, can cause invasive pneumococcal diseases (IPDs). To prevent the aggravation of IPDs, it is important to enhance host immune defense against S. pneumoniae. Hochuekkito (HET) is expected to have an immunostimulatory effect against infections. METHODS: HET was administrated by gavage to adult BALB/cA mice before and after intranasal inoculation of S. pneumoniae. We evaluated the effect of HET on pneumococcal nasal colonization and subsequent development of lethal pneumococcal infections...
April 25, 2024: Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy
https://read.qxmd.com/read/38670455/successful-maintenance-treatment-of-disseminated-nocardiosis-with-cerebral-abscess-in-a-severely-immunocompromised-patient-allergic-to-trimethoprim-sulfamethoxazole-using-moxifloxacin-and-high-dose-minocycline-a-case-report
#13
Hiroshi Yamamoto, Hirokazu Kuroda, Nobuhiro Hiramoto, Toshikazu Hasuike, Asako Doi, Hiroaki Nishioka
Nocardiosis in patients after allogeneic hematopoietic stem cell transplantation (HSCT) is rare, but is associated with a significant mortality risk. Although trimethoprim-sulfamethoxazole (TMP/SMX) remains the cornerstone of nocardiosis treatment, optimal alternative therapies for patients intolerant to TMP/SMX are not well-established. Herein, we report a case of disseminated nocardiosis with bacteremia and multiple lesions in the lungs and brain caused by Nocardia farcinica, in a 60-year-old man who had previously undergone allogeneic HSCT and was receiving immunosuppressants for severe chronic graft-versus-host disease...
April 24, 2024: Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy
https://read.qxmd.com/read/38657704/disease-burden-of-main-bacterial-infections-in-japan-2015-2020-a-population-level-study
#14
JOURNAL ARTICLE
Hiromi Hibino, Taito Kitano, Toshiaki Azuma, Ryuji Koizumi, Nobuaki Matsunaga, Shinya Tsuzuki, Norio Ohmagari
INTRODUCTION: Comprehensive evidence about the burden of infectious diseases in the Western Pacific Region is scarce. We thus examined the disease burden of infectious diseases in Japan in terms of disability-adjusted life years (DALYs). METHODS: We extracted national claims data from Japan's universal health insurance system to estimate the burden of disease for selected infections between 2015 and 2020 using DALYs. The mortality rate, disability duration and severity weight of each disease were estimated based on national data and literature reviews...
April 22, 2024: Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy
https://read.qxmd.com/read/38636933/evaluating-the-association-of-body-mass-index-with-covid-19-severity-and-mortality-using-japanese-administrative-claims-data
#15
JOURNAL ARTICLE
Waki Imoto, Yasutaka Ihara, Takumi Imai, Mitsuhiro Tamoto, Tatoi Ibuki, Koichi Yamada, Yukihiro Kaneko, Ayumi Shintani, Hiroshi Kakeya
INTRODUCTION: Obesity is a risk factor for aggravation of and mortality from coronavirus disease 2019 (COVID-19). We aimed to investigate the relationship between COVID-19 and Body Mass Index (BMI) in the Japanese population. METHODS: We used administrative claims data from an advanced treatment hospital in Japan and extracted data from patients hospitalized for COVID-19. The exposure variable was BMI measured at the time of admission, and the study outcomes were progression to critical illness and death...
April 16, 2024: Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy
https://read.qxmd.com/read/38631479/complicated-pneumonia-caused-by-group-a-streptococcus-in-children-2022-2023-infectious-season-outbreak-and-update-on-clinical-characteristics
#16
JOURNAL ARTICLE
Magdalena Grochowska, Agnieszka Strzelak, Katarzyna Krenke
BACKGROUND: An increased incidence of group A Streptococcus (GAS) infections has been observed in pediatric population post-COVID-19 pandemic. While the majority of reports refer to scarlet fever or invasive GAS disease, detailed data on pulmonary manifestations such as complicated community-acquired pneumonia (CAP) are scarce. The aim of this study was to assess the contribution of GAS to complicated CAP in children during the 2022/2023 infectious season. METHODS: We retrospectively analyzed the etiology and clinical presentation of complicated CAP patients hospitalized in our tertiary care center in Warsaw, Poland, between August 2022 and May 2023...
April 15, 2024: Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy
https://read.qxmd.com/read/38599283/japanese-spotted-fever-complicated-by-acute-sensorineural-hearing-loss
#17
Motohiro Shingu, Chieko Fujishima, Shigeo Hara, Hiroaki Nishioka
Japanese spotted fever is an emerging rickettsiosis caused by Rickettsia japonica and is characterized by high fever, rash, and eschar formation. Other symptoms are often vague and nonspecific and include headaches, nausea, vomiting, and myalgia. We present a case of a 46-year-old woman with Japanese spotted fever, complicated by transient bilateral sensorineural hearing loss and presenting cutaneous IgM/IgG immune complex vasculitis. The patient was admitted with a history of several days of high fever, generalized skin erythema, and hearing impairment...
April 8, 2024: Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy
https://read.qxmd.com/read/38588797/fourth-national-japanese-antimicrobial-susceptibility-pattern-surveillance-program-bacterial-isolates-from-patients-with-complicated-urinary-tract-infections
#18
JOURNAL ARTICLE
Kanao Kobayashi, Satoshi Takahashi, Mitsuru Yasuda, Jun Miyazaki, Koichiro Wada, Masahiro Matsumoto, Hiroshi Hayami, Shingo Yamamoto, Hiroshi Kiyota, Junko Sato, Tetsuya Matsumoto, Naoki Hasegawa, Intetsu Kobayashi, Naoya Masumori, Takahiro Kimura, Hiroki Yamada, Tohru Nakagawa, Tomoyuki Kaneko, Kazumasa Matsumoto, Tetsuya Fujimura, Jun Kamei, Kiyohito Ishikawa, Kiyohide Fujimoto, Yasushi Nakai, Katsumi Shigemura, Takuya Sadahira, Nobuyuki Hinata, Hiroyuki Kitano, Masuo Yamashita, Tomihiko Yasufuku, Hisao Komeda, Yoshiki Hiyama, Yoshito Takahashi, Sojun Kanamaru, Masaya Murakami, Soichi Arakawa, Daisuke Yamada, Koji Mita, Ryoichi Hamasuna, Kazushi Tanaka, Masanori Matsukawa, Eiichiro Takaoka, Masanobu Shigeta, Tadasu Takenaka, Masashi Nishino, Satoshi Ishitoya, Shohei Hayakawa, Kazuhiro Okumura, Masakatsu Ueda
INTRODUCTION: Antimicrobial susceptibility patterns of bacterial pathogens isolated from patients with complicated urinary tract infections were analyzed using the national surveillance data, comprising 793 bacterial strains from eight clinically relevant species. MATERIALS AND METHODS: Data were collected for the fourth national surveillance project from July 2020 to December 2021 by the Japanese Society of Chemotherapy, the Japanese Association for Infectious Disease, and the Japanese Society of Clinical Microbiology...
April 6, 2024: Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy
https://read.qxmd.com/read/38588796/nationwide-epidemiology-and-health-resource-use-among-children-with-covid-19-in-japan
#19
JOURNAL ARTICLE
Yusuke Okubo, Yosuke Nakabayashi, Kenta Ito, Kazuhiro Uda, Isao Miyairi
BACKGROUND: The COVID-19 pandemic posed substantial challenges to healthcare systems. Understanding the responses of pediatric health services is crucial for future pandemic planning and preparedness, yet such data remains limited. METHODS: In this retrospective cohort study, we analyzed data from administrative databases developed by Japan Medical Data Center and DeSC Healthcare Inc. The dataset comprised records of 2,612,511 children, totaling 60,224,888 person-months, from January 2020 to May 2022...
April 6, 2024: Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy
https://read.qxmd.com/read/38583801/tuberculous-aneurysm-diagnosed-by-ct-guided-biopsy-after-stent-graft-replacement-a-case-report
#20
Yoshito Homma, Takashi Harada, Takeshi Inoue, Junya Nakamura, Haruka Kondo, Sayaka Tachibana, Tomoya Katsuta, Koji Inoue
A tuberculous aneurysm is an uncommon extrapulmonary tuberculosis and is usually fatal. The best way to treat it involves a combination of open surgery and medical treatment. However, it can be challenging to diagnose a tuberculous aneurysm. In this report, we describe a patient with a tuberculous aneurysm who was treated with stent-graft replacement and CT-guided biopsy for diagnosis, followed by nine months of anti-tuberculosis therapy. Despite one week of anti-tuberculous therapy, her fever persisted. A CT scan revealed new, well-defined nodules measuring 1-2mm in the lungs and hepatomegaly, indicating complications of miliary tuberculosis...
April 5, 2024: Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy
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