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Endocrine Practice

Kelvin Onyeka Memeh, Jeannine Esther Palacios, Rihan Khan, Marlon Alex Guerrero
INTRODUCTION: Accurate pre-operative image localization is critical in selection of minimally invasive parathyroidectomy (MIP) as a surgical treatment approach in patients with primary hyperparathyroidism (PHPT). Sestamibi scan, ultrasound, computed tomography and conventional magnetic resonance imaging (MRI) has varying accuracy in localizing parathyroid adenoma. Our group had previously shown that 4D MRI is more accurate than conventional imaging in identifying single adenomas. In this study, we set out to determine if 4D-MRI is able to accurately localize the quadrant of the adenoma...
January 18, 2019: Endocrine Practice
Xinxin Chen, Lulu Chen, Xiaolan Lian, Chao Liu, Zhongyan Shan, Bingyin Shi, Lixin Shi, Nanwei Tong, Jianping Weng, Jiajun Zhao, Yongze Li, Weiping Teng, Shu Wang
OBJECTIVE: Epidemiologic studies on the relationship between iodine and thyroid antibodies were inconsistent. Iodine nutrition, genetic and environmental factors have been shown to modify the effects of iodine on thyroid autoimmunity. We investigated the relationship between urinary iodine concentration (UIC) and thyroglobulin antibodies (TgAb) in individuals living in iodine sufficient areas in this cross-sectional study. METHODS: A total of 15008 participants were recruited according to the age range of China population in our study...
January 18, 2019: Endocrine Practice
Tracy L Setji, Courtney Page, Neha Pagidipati, Benjamin A Goldstein
OBJECTIVE: This study evaluated whether there is a difference in the proportion of patients with type 2 diabetes who achieve an A1c <7% within one year following treatment by an endocrinologists or PCP. RESEARCH DESIGN AND METHODS: We conducted a retrospective, propensity-matched study of patients with type 2 diabetes that are not optimally controlled seen within our health system from 2007-2016. We assessed differences in short term health outcomes for patients following an endocrinologist visit compared to a PCP visit...
January 18, 2019: Endocrine Practice
Sara Ahmadi, Taofik Oyekunle, Xiaoyin 'Sara' Jiang, Randall Scheri, Jennifer Perkins, Michael Stang, Sanziana Roman, Julie A Sosa
Abtract Background: This study compares the American Thyroid Association (ATA) classification system with the 2017 Thyroid Imaging Reporting and Data System (TI-RADS) for predicting cancer risk in thyroid nodules. METHODS: This is a retrospective review of ultrasound imaging of all adult patients with thyroid nodules >5mm who underwent thyroidectomy at a tertiary care hospital in 2016. We assessed the ability of either system to predict malignancy based on surgical histopathology. Sensitivity, specificity, negative (NPV) and positive predictive values (PPV), and area-under-the-curve (AUC) were calculated and compared using McNemar's, Fisher's exact, or DeLong's tests...
January 18, 2019: Endocrine Practice
Kalyani Murthy, Gerard J Ondrey, Natasha Malkani, Gowri Raman, Mary Beth Hodge, Andrew J Marcantonio, Joseph G Verbalis
OBJECTIVE: Hyponatremia decreases bone mineral density and a major risk factor for fragility fractures. Objectives of our systematic review and meta-analysis were to analyze the overall effects of hyponatremia on bone fractures, osteoporosis and mortality. METHODS: We extracted data from MEDLINE®, Cochrane Central, and EMBASE 1960-2017 and conference abstracts from 2007-2017. We included studies with data on serum sodium, fractures, bone density, or diagnoses of osteoporosis...
January 18, 2019: Endocrine Practice
Paul Marcet, Jason Paluzzi, Anthony Morrison, Fernando L Vale
OBJECTIVE: To determine the rate of hormone replacement therapy (HRT) after transsphenoidal surgery (TSS) for pituitary apoplexy (PA) vs. elective resection of a null cell (NC) macroadenoma. METHODS: A retrospective cohort study was performed. Data was collected on all consecutive patients who underwent TSS surgery from December 31, 2000 to December 31, 2016. Patients were split into two groups: 1) patients that presented with PA, and 2) patients that underwent elective TSS for NC macroadenoma...
January 18, 2019: Endocrine Practice
Juan Delgado, Alicia Armstrong, Ricardo Correa, Richard Comi
OBJECTIVES: To our knowledge, no prior research has explored the prevalence of wearing CGM's and/or insulin pumps among in-training fellows and their perception of doing so as part of their education. Our objectives therefore are: to estimate the frequency with which wearing a CGM and/or insulin pump is used as a learning opportunity and to explore the main motivators and perception on its value. METHODS: A multiple-choice survey that addressed fellow's level of training, type of fellowship training program, and use of CGM and/or insulin pump among fellows was sent to all ACGME endocrinology, diabetes and metabolism program coordinators or programs directors...
January 18, 2019: Endocrine Practice
Michael W Yeh, Hui Zhou, Eric J Kuo, Annette L Adams, Ning Li, Philip I Haigh
OBJECTIVE: The natural biochemical history of untreated primary hyperparathyroidism (PHPT) is poorly understood. The purpose of this study was to determine the extent of biochemical fluctuations in patients with PHPT. DESIGN: Retrospective cohort study from January 1, 1995 to December 31, 2014. METHODS: Serum calcium and parathyroid hormone (PTH) levels in patients with classic (Ca > 10.5 mg/dL, PTH > 65 pg/mL) and non-classic (Ca > 10...
January 18, 2019: Endocrine Practice
Dong-Mei Liu, Lin-di Jiang, Lu Gan, Yang Su, Fei Li
OBJECTIVE: To investigate the sex- and age-specific association between the serum uric acid level and the body mass index (BMI). METHODS: A total of 144,856 subjects aged 20-79 years of age were enrolled in this cross-sectional study. The serum uric acid level, renal function, hepatic function, and the lipid profile were investigated. RESULTS: The prevalence of hyperuricemia decreased with age in men but increased in women. In men, the correlation coefficient between the serum urate level and the BMI declined steadily with age...
January 18, 2019: Endocrine Practice
Raya A Almazrouei, Amir H Sam, Karim Meeran, Fausto Palazzo
No abstract text is available yet for this article.
January 18, 2019: Endocrine Practice
Brad H Kimura, Farhad Farjoudi, Christopher J Hupfeld
No abstract text is available yet for this article.
January 18, 2019: Endocrine Practice
Shereen Ezzat, Gudrun Martina Caspar-Bell, Constance L Chik, Marie-Claire Denis, Marie-Ève Domingue, Syed Ali Imran, Michelle D Johnson, Heather A Lochnan, B L Grégoire Nyomba, Ally Prebtani, Rowena Ridout, Juan Andres Rivera Ramirez, Stan Van Uum
OBJECTIVE: To clarify selection of medical therapy following transsphenoidal surgery in patients with acromegaly, based on growth hormone/insulin like growth factor -1 (GH/IGF-1) response and glucometabolic control. METHODS: We carried out a systematic literature review on three of the best studied and most practical predictive markers of somatostatin analogues (SSA) response: somatostatin receptor (SSTR) expression, tumor morphologic classification, and T2-weighted MRI signal intensity...
January 18, 2019: Endocrine Practice
Omer Slook, Sigal Levy, Ilana Slutzky-Shraga, Gloria Tsvetov, Eyal Robenshtok, Ilan Shimon, Carlos Benbassat, Dania Hirsch
OBJECTIVE: This institutional study sought to retrospectively evaluate disease progression and survival of patients with differentiated thyroid cancer (DTC) and bone metastases (BM) and to investigate variables predictive of better long-term outcomes. METHODS: The Rabin Medical Center Thyroid Cancer Registry was searched for patients with bone-metastatic DTC. Variables including patients' gender and age, pathology of the thyroid tumor and characteristics of BM were retrieved and analyzed in association with disease progression and mortality...
January 18, 2019: Endocrine Practice
Neha D Karajgikar, Pooja Manroa, Runa Acharya, Ronald A Codario, Jodie A Reider, Amy C Donihi, Rose A Salata, Mary T Korytkowski
Objective To determine the efficacy and safety of a DKA-Power Plan(PP) for guiding IV insulin infusions prior to anion gap (AG) closure and administering subcutaneous (SC) insulin ≥1 hour before discontinuing IV insulin. Methods Retrospective chart review of patients with DKA before (Pre-PP) (n = 60) and following (Post-PP) (n = 60) implementation of a DKA-PP. Groups were compared for percentage of patients for whom IV insulin therapy was continued until AG closure, the percentage of patients receiving SC insulin ≥1hr before discontinuation of IV insulin, and percentage of patients with rebound DKA during the index hospitalization...
January 18, 2019: Endocrine Practice
Yunting Wang, Xiaoya Zheng, Xin Xie, Wenjie Qian, Lingmin Zhang, Wei Ren
OBJECTIVE: Adult growth hormone deficiency (AGHD) patients have an increased cardiovascular morbidity and mortality. Adipsin as an adipokine that is significantly correlated with metabolism disease, especially in people with obesity. The objective of our study was to compare AGHD patients with healthy subjects to evaluate whether adipsin levels are closely related to glycolipid metabolism and cardiovascular risks in AGHD patients. METHODS: Our study included 88 AGHD patients and 88 age-, weight- and BMI-matched healthy subjects...
January 18, 2019: Endocrine Practice
Amit Akirov, Anna M Sawka, Sharon Ben-Baruch, Jeffrey Lipton, Shereen Ezzat
Graft-versus-host disease (GVHD) is an immune phenomenon that occurs in 30-70% of patients after allogeneic hematopoietic stem cell transplantation. Chronic GVHD is a state of immune dysregulation wherein, depending on the severity and organ involved, patients may require prolonged treatment with additional or higher corticosteroids and other immunosuppressive agents. Endocrine manifestations following HST can arise as a consequence of the primary disease or its treatment, including chemotherapeutic agents, corticosteroid, radiation, or GVHD...
January 18, 2019: Endocrine Practice
Huy Gia Vuong, Thao T K Tran, Andrey Bychkov, Chan Kwon Jung, Tadao Nakazawa, Kennichi Kakudo, Ryohei Katoh, Tetsuo Kondo
Introduction It is still controversial as to how the reclassification of non-invasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) affects the risk of malignancy (ROM) in The Bethesda System for Reporting Thyroid Cytopathology (TBSRTC). This meta-analysis was aimed to investigate the impact of NIFTP on the ROM in each TBSRTC category. Methods We accessed three electronic databases including PubMed, Web of Science, and Scopus to search for relevant data from January 2016 to July 2018...
January 18, 2019: Endocrine Practice
(no author information available yet)
No abstract text is available yet for this article.
January 2019: Endocrine Practice
Derek LeRoith
No abstract text is available yet for this article.
January 2019: Endocrine Practice
Gabriela Brenta, Alejandro Sosa Caballero, Maria Tereza Nunes
OBJECTIVE: Latin American Thyroid Society (LATS) Hypothyroidism Clinical Practice Guidelines recommend case finding of hypothyroid patients in multiple and different situations that agree with other Society guidelines. However, the detection of hypothyroidism in type 2 diabetes mellitus (T2DM) or metabolic syndrome (MetS) patients is not mentioned in particular. In the recent years, several basic and epidemiologic studies have appeared showing that a lower thyroid function and MetS/T2DM are associated...
January 2019: Endocrine Practice
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