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Allergy and Asthma Proceedings:

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https://read.qxmd.com/read/30563587/scoring-systems-for-allergies-and-asthma-in-clinical-research-and-practice
#1
Sasha A Alvarado, Marjan Nassiri, Sami L Bahna
BACKGROUND: Scoring systems are increasingly being developed for various diseases, including asthma and allergic disorders, with the objective of improving the classification of disease severity and the assessment of efficacy of therapeuticmodalities. OBJECTIVE: This review provided concise summaries of published scoring systems used for allergic rhinitis, asthma, atopicdermatitis, urticaria, Stevens-Johnson syndrome/toxic epidermal necrolysis, eosinophilic esophagitis, and systemic allergicreactions (anaphylaxis)...
December 18, 2018: Allergy and Asthma Proceedings:
https://read.qxmd.com/read/30582496/a-cross-sectional-population-based-survey-of-u-s-adults-with-symptoms-of-chronic-rhinosinusitis
#2
James N Palmer, John C Messina, Robert Biletch, Kirk Grosel, Ramy A Mahmoud
Background: Chronic rhinosinusitis (CRS) is believed to create a substantial population-level disease burden in the United States due to its high prevalence and significant disease morbidity, but many studies of CRS epidemiology are based on administrative or historical record sources rather than primary population sources. Objective: To characterize CRS symptoms, burden, and patient characteristics by using a primary U.S. population-based representative sample. Methods: A demographically and geographically representative sample of 10,336 U...
January 14, 2019: Allergy and Asthma Proceedings:
https://read.qxmd.com/read/30582501/a-cross-sectional-study-of-the-prevalence-of-food-allergies-among-children-younger-than-ages-14-years-in-a-beijing-urban-region
#3
Li Sha, Mingjun Shao, Chuanhe Liu, Yongning Wu, Yuzhi Chen
Background: The prevalence of food allergies has increased over the past several decades, but little is known about this issue in Beijing. Objective: The objectives of this study were to assess the prevalence of food allergies in the Beijing urban area and to summarize the clinical features and common food allergens in children <14 years of age. Methods: We conducted a cross-sectional study of children ages 0-14 years who were recruited from 10 kindergartens and 20 primary and middle schools in two communities in the central region (Xicheng district)...
January 1, 2019: Allergy and Asthma Proceedings:
https://read.qxmd.com/read/30582500/abstracts-presented-at-the-new-england-society-of-allergy-october-20-21-2018-plymouth-ma
#4
(no author information available yet)
No abstract text is available yet for this article.
January 1, 2019: Allergy and Asthma Proceedings:
https://read.qxmd.com/read/30582499/for-the-patient
#5
(no author information available yet)
No abstract text is available yet for this article.
January 1, 2019: Allergy and Asthma Proceedings:
https://read.qxmd.com/read/30582498/pearls-and-pitfalls-of-food-challenges-in-infants
#6
Matthew Greenhawt
An oral food challenge (OFC) is considered the diagnostic criterion standard procedure for evaluation of a suspected food allergy in patients of any age. This can be accomplished as either an open or a blinded challenge. In recent years, the open OFC has become an acceptable and practical office-based practice. With the advent of new early peanut introduction guidelines, there is a critical need to potentially perform OFC in very young infants between the ages of 4 and 12 months of life. Experience from multiple recent randomized controlled clinical trials indicates that such OFCs are both safe and feasible, although the extent to which providers in the clinical setting are comfortable and experienced with OFCs in this population is unclear...
January 1, 2019: Allergy and Asthma Proceedings:
https://read.qxmd.com/read/30582497/direct-oral-amoxicillin-challenge-without-preliminary-skin-testing-in-adult-patients-with-allergy-and-at-low-risk-with-reported-penicillin-allergy
#7
Merin Kuruvilla, Jennifer Shih, Kiran Patel, Nicholas Scanlon
Introduction: Ten percent of hospitalized patients report penicillin allergy; however, recent studies indicate that ∼98% of these patients are not acutely hypersensitive. Unconfirmed penicillin allergy poses public health risks, and an evaluation of penicillin allergy labels is recommended to improve antibiotic stewardship. Although the most widely accepted protocol is penicillin skin testing, followed by oral amoxicillin challenge, time constraints and resources may preclude this. Recent literature supports the safety and efficacy of direct oral amoxicillin challenge in individuals at low risk...
January 1, 2019: Allergy and Asthma Proceedings:
https://read.qxmd.com/read/30582495/anaphylaxis-risk-factors-for-hospitalization-and-intensive-care-a-comparison-between-adults-and-children-in-an-upstate-new-york-emergency-department
#8
Britta K Sundquist, Jaison Jose, Daniel Pauze, Denis Pauze, Hongyue Wang, Kirsi M Järvinen
Background: Anaphylaxis is an acute, systemic allergic reaction that can be life threatening, and with an increasing incidence and costs associated with hospitalization and intensive care. Objective: To assess the risk factors for hospitalization by comparing pediatric and adult patients. Methods: We performed a retrospective chart review for patients with anaphylactic reactions who presented to the Albany Medical Center emergency department between 2005 and 2012. Results: We identified 267 anaphylactic reactions in 258 patients (143 adults)...
January 1, 2019: Allergy and Asthma Proceedings:
https://read.qxmd.com/read/30582494/systemic-reaction-rates-with-omalizumab-subcutaneous-immunotherapy-and-combination-therapy-in-children-with-allergic-asthma
#9
Daniel Har, Min Jung Lee
Background: For children with moderate-to-severe persistent allergic asthma, omalizumab is effective. However, it is expensive, and there are no current guidelines for discontinuation. Subcutaneous immunotherapy (SCIT) is the only approach that can provide persistent beneficial effects after treatment is discontinued. However, SCIT is contraindicated in poorly controlled asthma. Therefore, we performed, to our knowledge, the first U.S. study that exclusively compared the safety of omalizumab, SCIT, and combination (omalizumab and SCIT) therapy in children with allergic asthma...
January 1, 2019: Allergy and Asthma Proceedings:
https://read.qxmd.com/read/30582493/effect-of-inhaled-corticosteroids-on-serum-periostin-levels-in-adult-patients-with-mild-moderate-asthma
#10
Bhupinder Solanki, Anupam Prakash, Harmeet S Rehan, Lalit K Gupta
Background: Periostin is an extracellular matrix protein, and its expression is upregulated in airway epithelial cells in patients with bronchial asthma. Periostin may be a key molecule linked to type 2 T-helper cell inflammation. Inhaled corticosteroids (ICS) may suppress periostin-induced asthmatic inflammation. This study estimated the serum periostin levels in patients with asthma and evaluated the effect of ICS on the levels of periostin, peak expiratory flow rate (PEFR), and quality of life (QOL). Methods: The study design was prospective, open label, and observational...
January 1, 2019: Allergy and Asthma Proceedings:
https://read.qxmd.com/read/30582492/clinical-burden-of-asynchrony-in-patients-with-asthma-when-using-metered-dose-inhalers-for-control
#11
Thomas J Ferro, Agnes S Sundaresan, James M Pitcavage, Jasmina I Ivanova, Luke Schmerold, Rinat Ariely, Ruchir Parikh, Wendy Y Cheng
Background: Asynchrony, or lack of coordination between inhalation and actuation when using a pressurized metered-dose inhaler (MDI), could theoretically impact the delivery of inhaled medications and treatment efficacy. Objective: To assess the real-world association between asynchrony and clinical outcomes among patients with asthma who receive controller therapy delivered by MDIs. Methods: A cohort of patients was assembled via electronic health records. The patients were aged ≥12 years, with one or more documentations of an asthma diagnosis, no diagnosis of chronic obstructive pulmonary disease, and two or more prescriptions for an inhalation aerosol corticosteroid alone or with long-acting beta-2-agonist delivered via MDI...
January 1, 2019: Allergy and Asthma Proceedings:
https://read.qxmd.com/read/30582491/update-on-peanut-allergy-prevention-and-immunotherapy
#12
Quindelyn S Cook, Edwin H Kim
Background: The prevalence of food allergy is steadily increasing, and the burden of food allergy has become significant. However, treatments for food allergy remain experimental. Objective: To review advances in the past 18 months for the prevention and treatment of food allergies, with a particular focus on peanut allergy. Methods: Recently published trials on the use of oral immunotherapy (OIT), sublingual immunotherapy (SLIT), and epicutaneous immunotherapy (EPIT) as well as updates on the implementation of the early introduction of peanut guidelines were identified...
January 1, 2019: Allergy and Asthma Proceedings:
https://read.qxmd.com/read/30582490/new-and-evolving-therapies-for-hereditary-angioedema
#13
Sara Barmettler, Yu Li, Aleena Banerji
Hereditary angioedema (HAE) is a rare, autosomal dominant, genetic disorder associated with a deficiency in C1 inhibitor protein. HAE is characterized by recurrent and unpredictable episodes of swelling of the extremities, abdomen, face, and upper airway. There are several newly approved drugs as well as investigational products that are currently under study for the management of patients with HAE, with the potential to optimize care and improve quality of life for patients with HAE. We reviewed the evolution of HAE treatment options in the United States and discussed mechanisms of action, routes of administration, and efficacy of these therapies...
January 1, 2019: Allergy and Asthma Proceedings:
https://read.qxmd.com/read/30582489/clinical-updates-in-aspirin-exacerbated-respiratory-disease
#14
Tanya M Laidlaw
Background: Aspirin-exacerbated respiratory disease (AERD), a syndrome that includes asthma, recurrent nasal polyps, and pathognomonic reactions to aspirin and other nonselective cyclooxygenase inhibitors, is still not fully understood and lacks specific disease-modifying therapeutic options. Objective: To review the most recent clinical updates in the evaluation and treatment of patients with AERD. Methods: Recent clinical research studies relevant to patients with AERD were reviewed. Results: Multiple new biologics are available for the treatment of severe asthma, several of which have been specifically studied and determined to be efficacious in the subset of patients with asthma who are also aspirin sensitive...
January 1, 2019: Allergy and Asthma Proceedings:
https://read.qxmd.com/read/30582488/inflammation-and-allergic-disease-an-irrefutable-combination
#15
Joseph A Bellanti, Russell A Settipane
No abstract text is available yet for this article.
January 1, 2019: Allergy and Asthma Proceedings:
https://read.qxmd.com/read/30336791/impact-of-patient-satisfaction-with-his-or-her-inhaler-on-adherence-and-asthma-control
#16
Vicente Plaza, Jordi Giner, Myriam Calle, Paula Rytilä, Carlos Campo, Paula Ribó, Antonio Valero
Background: Asthma guidelines recommend considering patient preferences for inhaler choice. However, few studies have assessed the impact of patient satisfaction with an inhaler on adherence and health outcomes. Objective: To assess the impact of patient satisfaction with an inhaler on adherence and health outcomes in asthma. Methods: In a cross-sectional, observational, multicenter study, 778 patients with moderate or severe asthma and who were treated with maintenance inhalers completed a number of scales and questionnaires: the Feeling of Satisfaction with Inhaler (FSI-10) questionnaire, the Treatment Satisfaction Questionnaire for Medication, the Test of Adherence to Inhalers (TAI), the Morisky-Green questionnaire, and the Asthma Control Test (ACT)...
November 18, 2018: Allergy and Asthma Proceedings:
https://read.qxmd.com/read/30326990/cross-sectional-study-on-asthma-insights-and-management-in-the-gulf-and-russia
#17
Ashraf Alzaabi, Majdy Idrees, Naser Behbehani, Musa R Khaitov, Kaan Tunceli, Eduardo Urdaneta, Nancy Awad, Mohamed Safwat
Background: Asthma is a chronic and complex lung disease that is not completely understood. It involves airway inflammation, reversible airflow obstruction, and bronchial hyperresponsiveness. The most common symptoms are recurrent wheezing, chest tightness, shortness of breath, and coughing. Objective: The Asthma Insights and Management study gathered information on the burden of asthma in the Gulf region (United Arab Emirates, Kuwait, Saudi Arabia) and Russia. Methods: This was a cross-sectional, multinational, noninterventional, two-phase study that collected data from patients ages ≥ 12 years, through interviews and a survey questionnaire...
November 16, 2018: Allergy and Asthma Proceedings:
https://read.qxmd.com/read/30428957/a-cross-sectional-population-based-survey-of-u-s-adults-with-symptoms-of-chronic-rhinosinusitis
#18
James N Palmer, John C Messina, Robert Biletch, Kirk Grosel, Ramy A Mahmoud
BACKGROUND: Chronic rhinosinusitis (CRS) is believed to create a substantial population-level disease burden in the UnitedStates due to its high prevalence and significant disease morbidity, but many studies of CRS epidemiology are based onadministrative or historical record sources rather than primary population sources. OBJECTIVE: To characterize CRS symptoms, burden, and patient characteristics by using a primary U.S. population- basedrepresentative sample. METHODS: A demographically and geographically representative sample of 10,336 U...
November 14, 2018: Allergy and Asthma Proceedings:
https://read.qxmd.com/read/30401330/effect-of-indoor-air-quality-on-the-natural-history-of-asthma-in-an-urban-population-in-poland
#19
Barbara Piekarska, Bożena L Stankiewicz-Choroszucha, Adam J Sybilski, Konrad Furmańczyk, Stanisław Jaworski, Artur Z Białoszewski, Anna Kłak, Agnieszka Lipiec, Artur Walkiewicz, Aneta Tomaszewska, Filip Raciborski, Bolesław K Samoliński
Background: Indoor air pollution may have an impact on asthma. Objective: To evaluate the influence of indoor air pollution on the natural history of asthma. Methods: Data collection by using the European Community Respiratory Health Survey and International Study of Asthma and Allergies in Childhood standardized questionnaire (N = 18,617) and medical examinations (N = 4783) in selected Polish regions was used. Statistical analysis was performed by using the χ² test. A value of p < 0.05 was considered statistically significant...
November 1, 2018: Allergy and Asthma Proceedings:
https://read.qxmd.com/read/30401329/extrinsic-warming-of-low-osmolality-iodinated-contrast-media-to-37%C3%A2-c-reduced-the-rate-of-allergic-like-reaction
#20
Bin Zhang, Jing Liu, Yuhao Dong, Baoliang Guo, Zhouyang Lian, Hui Yu, Xiaoning Luo, Xiaokai Mo, Lu Zhang, Wenhui Huang, Fusheng Ouyang, Xinyun Li, Changhong Liang, Shuixing Zhang
Background: Although there is good evidence that warming of contrast media changes the bolus kinetics and injection pressure of iodinated contrast media, there has been little evidence that it affects clinical adverse event rates in a meaningful way. Objective: To determine whether the extrinsic warming of low-osmolality iodinated contrast media to 37°C reduced adverse reactions. Methods: Data on adverse reactions were collected from two cohorts, one of which used contrast media at room temperature and the other in which contrast media were warmed to 37°C before administration...
November 1, 2018: Allergy and Asthma Proceedings:
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