Wangde Dai, Jianru Shi, Prabha Siddarth, Lifu Zhao, Juan Carreno, Michael T Kleinman, David A Herman, Rebecca J Arechavala, Samantha Renusch, Irene Hasen, Amanda Ting, Robert A Kloner
PURPOSE: We investigated the effects of exposure to electronic cigarettes (E-cig) vapor on the sizes of the no-reflow and myocardial infarction regions, and cardiovascular function compared to exposure to purified air and standard cigarette smoke. METHODS AND RESULTS: Sprague Dawley rats (both male and female, 6 weeks old) were successfully exposed to filtered air (n = 32), E-cig with nicotine (E-cig Nic+ , n = 26), E-cig without nicotine (E-cig Nic- , n = 26), or standard cigarette smoke (1R6F reference, n = 31)...
2023: Journal of Cardiovascular Pharmacology and Therapeutics