journal
Journals Clinical Microbiology and Infe...

Clinical Microbiology and Infection

https://read.qxmd.com/read/38648896/efficacy-and-safety-of-withholding-antimicrobial-therapy-in-children-with-cancer-fever-and-neutropenia-with-a-demonstrated-viral-respiratory-infection-a-randomized-clinical-trial
#21
JOURNAL ARTICLE
J P Torres, C Ibañez, R Valenzuela, S Bahamondes, V De la Maza, M Villarroel, P Coria, V Contardo, A M Álvarez, M Zubieta, V Gutierrez, K Ducasse, D Martínez, M E Santolaya
OBJECTIVES: To validate the efficacy and safety of withholding antimicrobial therapy in a new cohort of children with cancer and febrile neutropenia (FN) having a demonstrated viral respiratory tract infection (RTI). METHODS: Prospective, multicenter, non-inferiority, randomized study, approved by the ethical committee, in children presenting with FN at seven hospitals in Chile, evaluated at admission for diagnosis of bacterial and viral pathogens. Children who were positive for a respiratory virus (RV), negative for a bacterial pathogen and had a favorable evolution after 48-72 hours of antimicrobial therapy were randomized to either maintain or withhold antimicrobial therapy...
April 20, 2024: Clinical Microbiology and Infection
https://read.qxmd.com/read/38642896/re-unexpected-increase-of-severe-mycoplasma-pneumoniae-pneumonia-in-adults-in-southern-switzerland-by-garzoni-et-al
#22
LETTER
Souheil Zayet, Timothée Klopfenstein
No abstract text is available yet for this article.
April 18, 2024: Clinical Microbiology and Infection
https://read.qxmd.com/read/38642895/persistent-covid-19-in-immunocompromised-patients-israeli-society-of-infectious-diseases-consensus-statement-on-diagnosis-and-management
#23
REVIEW
Suzy E Meijer, Yael Paran, Ana Belkin, Ronen Ben-Ami, Yasmin Maor, Lior Nesher, Khetam Hussein, Galia Rahav, Tal Brosh-Nissimov
BACKGROUND: Immunocompromised patients with impaired humoral immunity are at risk for persistent COVID-19 (pCOVID), a protracted symptomatic disease with active viral replication. OBJECTIVES: To establish a national consensus statement on the diagnosis, treatment, management, isolation, and prevention of pCOVID in adults. SOURCES: We base our suggestions on the available literature, our own experience, and clinical reasoning. CONTENT: Literature on the treatment of pCOVID is scarce and consists of few case reports and case series...
April 18, 2024: Clinical Microbiology and Infection
https://read.qxmd.com/read/38621623/dual-centre-evaluation-of-the-fluorotype-mtbdr-version-2-assay-for-detection-of-mycobacterium-tuberculosis-complex-and-resistance-conferring-mutations-in-pulmonary-and-extrapulmonary-samples-from-denmark-germany-and-sierra-leone
#24
JOURNAL ARTICLE
Erik Svensson, Hannah Ketelsen, Sönke Andres, Dorte Bek Folkvardsen, Doris Hillemann, Ousman Conteh, Anders Norman, Stefan Niemann, Troels Lillebaek, Martin Kuhns
OBJECTIVE: We evaluated the ability of FluoroType MTBDR version 2 (FTv2; Hain Lifescience), a second-step real-time PCR assay, to simultaneously detect Mycobacterium tuberculosis complex (MTBC) DNA and mutations conferring resistance to rifampicin (RIF) and isoniazid (INH), in pulmonary and extrapulmonary samples from patients and compared them with corresponding cultures. METHODS: FTv2 MTBC was evaluated on 1815 and 432 samples from Denmark (DK) and Germany (DE)...
April 13, 2024: Clinical Microbiology and Infection
https://read.qxmd.com/read/38615819/-vagus-nerve-dysfunction-in-the-post-covid-19-condition-author-s-reply
#25
LETTER
Gemma Lladós, Marta Massanella, Roger Paredes, Lourdes Mateu
No abstract text is available yet for this article.
April 12, 2024: Clinical Microbiology and Infection
https://read.qxmd.com/read/38608872/the-impact-of-colonization-by-multi-drug-resistant-bacteria-on-graft-survival-risk-of-infection-and-mortality-in-recipients-of-solid-organ-transplant-systematic-review-and-meta-analysis
#26
REVIEW
Abdulellah Almohaya, Jordana Fersovich, R Benson Weyant, Oscar A Fernández García, Sandra M Campbell, Karen Doucette, Tamara Lotfi, Juan G Abraldes, Carlos Cervera, Dima Kabbani
BACKGROUND: The Global increase in colonization by multidrug-resistant (MDR) bacteria poses a significant concern. The precise impact of MDR colonization in solid organ transplant recipients (SOTR) remains not well established. OBJECTIVES: Assess the impact of MDR colonization on SOTR's mortality, infection, or graft-loss. DATA SOURCE: Data from PROSPERO, OVID Medline, Ovid EMBASE, Wiley Cochrane Library, ProQuest Dissertations, Theses Global, and SCOPUS, were systematically reviewed spanning from inception until March 20, 2023...
April 10, 2024: Clinical Microbiology and Infection
https://read.qxmd.com/read/38599464/association-of-microbiological-factors-with-mortality-in-escherichia-coli-bacteraemia-presenting-with-sepsis-septic-shock-a-prospective-cohort-study
#27
JOURNAL ARTICLE
Natalia Maldonado, Inmaculada López-Hernández, Luis Eduardo López-Cortés, Pedro María Martínez Pérez-Crespo, Pilar Retamar-Gentil, Andrea García-Montaner, Sandra De la Rosa Riestra, Adrián Sousa-Domínguez, Josune Goikoetxea, Ángeles Pulido-Navazo, María Del Valle Ortíz, Clara Natera-Kindelán, Alfredo Jover-Sáenz, Alfonso Del Arco-Jiménez, Carlos Armiñanzas-Castillo, Ana Isabel Aller-García, Jonathan Fernández-Suárez, Teresa Marrodán-Ciordia, Lucía Boix-Palop, Alejandro Smithson-Amat, José Ma Reguera-Iglesias, Fátima Galán-Sánchez, Alberto Bahamonde, Juan Manuel Sánchez Calvo, Isabel Gea-Lázaro, Inés Pérez-Camacho, Armando Reyes-Bertos, Berta Becerril-Carral, Álvaro Pascual, Jesús Rodríguez-Baño
OBJECTIVES: This study aimed to determine the association of E. coli microbiological factors with 30-day mortality in BSI patients presenting with a dysregulated response to infection (i.e., sepsis or septic shock). METHODS: Whole genome sequencing was performed on 224 E. coli isolates of patients with sepsis/septic shock, from 22 Spanish hospitals. Phylogroup, sequence type, virulence, antibiotic resistance and pathogenicity islands were assessed. A multivariable model for 30-day mortality including clinical and epidemiological variables was built, to which microbiological variables were hierarchically added...
April 8, 2024: Clinical Microbiology and Infection
https://read.qxmd.com/read/38599463/impact-of-high-performance-hpv-testing-to-improve-cervical-cancer-screening-in-china-a-prospective-population-based-multicenter-cohort-study
#28
JOURNAL ARTICLE
Jian Yin, Shaokai Zhang, Zhifang Li, Yufei Li, Hong Wang, Xun Zhang, Qinjing Pan, Wen Chen, Xiping Luo, Xibin Sun, Fanghui Zhao, Youlin Qiao
OBJECTIVES: The aim of the study was to evaluate the clinical performance of HBRT-H14, a real-time PCR-based assay that separates human papillomavirus (HPV) 16 and HPV18 from 12 other high-risk (HR) HPV types, in population according to Chinese guideline. METHODS: 9829 eligible women aged 21-64 years from Henan, Shanxi and Guangdong provinces were performed by HBRT-H14 testing and liquid-based cytology (LBC) screening at baseline and followed up for three-year...
April 8, 2024: Clinical Microbiology and Infection
https://read.qxmd.com/read/38588877/history-of-smallpox-vaccination-and-marked-clinical-expression-of-mpox-among-cases-notified-in-france-from-may-to-july-2022
#29
JOURNAL ARTICLE
Catarina Krug, Emilie Chazelle, Arnaud Tarantola, Harold Noël, Guillaume Spaccaferri, Isabelle Parent du Châtelet, Laura Zanetti, Hana Lahbib, Myriam Fayad, Florence Lot, Henriette De Valk, Didier Che, Bruno Coignard, Alexandra Mailles, Anne-Sophie Barret
OBJECTIVES: The aim was to estimate the effect of reported history of smallpox vaccination prior to 1980 on clinical expression of mpox. METHODS: We included all confirmed mpox cases identified by the national mpox surveillance system in France between May and July 2022. Cases tested positive for monkeypox virus or orthopoxviruses by PCR. Cases were interviewed by phone using a questionnaire documenting demographics, symptoms and exposures. To estimate the effect of smallpox vaccination on presence of marked mpox symptoms (association of fever, lymphadenopathy and extensive mucocutaneous lesions), we estimated prevalence ratios (PR) and 95% confidence intervals (CI) using Poisson regression models with robust standard errors...
April 6, 2024: Clinical Microbiology and Infection
https://read.qxmd.com/read/38583521/which-trials-do-we-need
#30
EDITORIAL
Leonard Leibovici
No abstract text is available yet for this article.
April 5, 2024: Clinical Microbiology and Infection
https://read.qxmd.com/read/38583520/the-case-for-the-aware-universal-guidelines-for-antibiotic-use
#31
JOURNAL ARTICLE
Paul Yonga, Céline Pulcini, Robert Skov, Jose R Paño-Pardo, Jeroen Schouten
No abstract text is available yet for this article.
April 5, 2024: Clinical Microbiology and Infection
https://read.qxmd.com/read/38583519/diagnostic-yield-of-molecular-diagnostics-for-the-atypical-pathogens-diagnostic-stewardship-is-warranted
#32
LETTER
Marloes Rigter, Sonja E van Roeden, Roos Barth, Marjolijn Wegdam-Blans
No abstract text is available yet for this article.
April 5, 2024: Clinical Microbiology and Infection
https://read.qxmd.com/read/38583518/comparative-efficacy-and-safety-of-pneumocystis-jirovecii-pneumonia-prophylaxis-regimens-for-people-with-hiv-a-systematic-review-and-network-meta-analysis-of-randomized-controlled-trials
#33
REVIEW
Connor Prosty, Khaled Katergi, Mark Sorin, Marianne Bou Rjeily, Guillaume Butler-Laporte, Emily G McDonald, Todd C Lee
BACKGROUND: Pneumocystis jirovecii pneumonia (PCP) is a common opportunistic infection among people living with HIV (PLWH), particularly among new and untreated cases. Several regimens are available for the prophylaxis of PCP including trimethoprim-sulfamethoxazole (TMP-SMX), dapsone-based regimens (DBRs), aerosolized pentamidine (AP), and atovaquone. OBJECTIVE: To compare the efficacy and safety of PCP prophylaxis regimens in PLWH by network meta-analysis. DATA SOURCES: Embase, MedLine, and CENTRAL from inception to June 21, 2023...
April 5, 2024: Clinical Microbiology and Infection
https://read.qxmd.com/read/38556214/time-to-positivity-is-a-risk-factor-for-death-among-patients-with-bloodstream-infections-a-population-based-cohort
#34
JOURNAL ARTICLE
Kevin B Laupland, Felicity Edwards, Zoe Dettrick, Patrick N A Harris
OBJECTIVES: Studies examining time to positivity (TTP) of blood cultures as a risk factor for death have shown conflicting results. The study objective was to examine the effect of TTP on all-cause-30-day case-fatality among a population-based cohort of patients with bloodstream infections (BSI). METHODS: A retrospective cohort study including all residents of Queensland, Australia with incident monomicrobial BSI managed in the publicly funded healthcare system from 2000 to 2019 was performed...
March 29, 2024: Clinical Microbiology and Infection
https://read.qxmd.com/read/38556213/the-impact-of-armed-conflict-on-the-development-and-global-spread-of-antibiotic-resistance-a-systematic-review
#35
REVIEW
Guido Granata, Eskild Petersen, Alessandro Capone, Daniele Donati, Benedetta Andriolo, Maya Gross, Stefania Cicalini, Nicola Petrosillo
BACKGROUND: Scant data are available on the link between armed conflicts and the development and spread of antimicrobial resistance. OBJECTIVES: We perfomed a systematic review with the aim to summarise the available data on the prevalence and features of antibiotic resistance and the causes of antibiotic resistance development during armed conflicts in the twenty-first century. METHODS: Data sources: PubMed and SCOPUS databases were searched from 1 January 2000 to 30 November 2023...
March 29, 2024: Clinical Microbiology and Infection
https://read.qxmd.com/read/38556212/features-of-cryptococcosis-among-652-hiv-seronegative-individuals-in-france-a-cross-sectional-observational-study-2005-2020
#36
JOURNAL ARTICLE
Olivier Paccoud, Marie Desnos-Ollivier, Florence Persat, Magalie Demar, Karine Boukris-Sitbon, Anne-Pauline Bellanger, Julie Bonhomme, Christine Bonnal, Françoise Botterel, Marie-Elisabeth Bougnoux, Sophie Brun, Sophie Cassaing, Estelle Cateau, Taieb Chouaki, Muriel Cornet, Eric Dannaoui, Nicole Desbois-Nogard, Marie-Fleur Durieux, Loïc Favennec, Arnaud Fekkar, Frederic Gabriel, Jean-Pierre Gangneux, Juliette Guitard, Lilia Hasseine, Antoine Huguenin, Solène Le Gal, Valérie Letscher-Bru, Caroline Mahinc, Florent Morio, Muriel Nicolas, Philippe Poirier, Stéphane Ranque, Gabrielle Roosen, Célia Rouges, Anne-Laure Roux, Milène Sasso, Alexandre Alanio, Olivier Lortholary, Fanny Lanternier
OBJECTIVES: We aimed to describe features and outcomes of cryptococcosis among HIV-seronegative individuals in a large surveillance network for cryptococcosis in France. METHODS: We included incident cases of cryptococcosis in HIV-seronegative individuals from 2005 to 2020. We compared patient characteristics, disease presentations, cryptococcal antigen (CrAg) results, and induction antifungal treatments according to underlying disease. We examined factors associated with 90-day mortality...
March 29, 2024: Clinical Microbiology and Infection
https://read.qxmd.com/read/38556211/-impact-of-the-covid-19-pandemic-on-antibiotic-prescribing-in-high-prescribing-primary-care-physicians-in-switzerland-author-s-reply
#37
LETTER
Soheila Aghlmandi, Julia Bielicki, Heiner C Bucher
No abstract text is available yet for this article.
March 29, 2024: Clinical Microbiology and Infection
https://read.qxmd.com/read/38556210/monetary-incentives-for-vaccination-effectiveness-and-unintended-consequences
#38
JOURNAL ARTICLE
Pol Campos-Mercade, Florian H Schneider
No abstract text is available yet for this article.
March 29, 2024: Clinical Microbiology and Infection
https://read.qxmd.com/read/38554928/ampicillin-susceptibility-testing-of-haemophilus-influenzae-in-the-routine-clinical-laboratory-by-the-eucast-methodology-compared-to-broth-microdilution-and-the-presence-of-ftsi-gene-mutations
#39
JOURNAL ARTICLE
Patrick D J Sturm, Noud T H Hermans, Adri G M van der Zanden, Cas J A Peters, Tanja Schülin
OBJECTIVES: To investigate the prevalence of ampicillin resistance in H. influenzae and the diagnostic accuracy of the EUCAST recommended disc diffusion method to detect the increasingly prevalent ampicillin resistance due to the presence of PBP3 alterations based on mutations in the ftsI gene. METHODS: During a 6-month period all consecutive non-duplicate H. influenzae isolates were prospectively collected and stored. MICs of ampicillin were determined by broth microdilution (BMD)...
March 28, 2024: Clinical Microbiology and Infection
https://read.qxmd.com/read/38552795/-stuck-in-pandemic-uncertainty-a-review-of-the-persistent-effects-of-covid-19-infection-in-immune-deficient-people
#40
REVIEW
Bevin Manuelpillai, Mackenzie Zendt, Emma Chang-Rabley, Emily E Ricotta
BACKGROUND: Immune-deficient/disordered people (IDP) are underrepresented in COVID-19 studies. Specifically, there is limited research on post-SARS-CoV-2 infection outcomes, including viral persistence and long-term sequelae in these populations. OBJECTIVES: This review aimed to examine the published literature on the occurrence of persistent SARS-CoV-2 positivity, relapse, reinfections, variant coinfection, and post-acute sequelae of COVID-19 in IDP. While the available literature largely centered on those with secondary immunodeficiencies, studies on people with inborn errors of immunity are also included...
March 27, 2024: Clinical Microbiology and Infection
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