International Urogynecology Journal and Pelvic Floor Dysfunction

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INTRODUCTION AND HYPOTHESIS: Our aim was to review our experience with Fournier's gangrene in female patients. METHODS: A retrospective review of ten consecutive female patients with Fournier's gangrene was performed. Etiological and predisposing factors, causative microbiological organisms, and clinical outcome were investigated. RESULTS: Mean age of the patients was 52.7 years, and the mean duration of hospitalization was 17.6 days. The etiologic origin of the gangrene was anorectal, dermatological, and urogenital infection in 50%, 20%, and 10% of patients, respectively...

BACKGROUND: India lacks prevalence and incidence data on obstetric fistula, a near miss maternal mortality. METHODOLOGY: Retrospective data were collected on obstetric fistula cases from hospital records of 24 tertiary care facilities during the period 2000-2006. RESULTS: Overall, 717 women underwent genital fistula repair, but medical records could be retrieved for only 401 (56%) cases. States of Bihar, Uttar Pradesh, and West Bengal had more than 100 cases each, while Karnataka had none...

No abstract text is available yet for this article.

No abstract text is available yet for this article.

INTRODUCTION AND HYPOTHESIS: This study describes pelvic organ support after childbirth. METHODS: This ancillary analysis of the Childbirth and Pelvic Symptoms Imaging Study compares pelvic organ prolapse quantification 6-12 months after childbirth among three cohorts of primiparous women: vaginal delivery with sphincter tear (n = 106), vaginal delivery without sphincter tear (n = 108), and cesarean without labor (n = 39). RESULTS: Of participants, 31...

INTRODUCTION AND HYPOTHESIS: We investigated whether the expression of alpha-1 antitrypsin (ATT), neutrophil elastase (NE), and lysyl oxidase-like protein 1 (LOXL-1) vary within the vagina in subjects with pelvic organ prolapse (POP). METHODS: Biopsies were obtained from the anterior and posterior vaginal wall of 22 women with POP (> or =stage 2 by POP-Q). The subjects were grouped by the most prominent defect: cystocele, cystocele plus uterine prolapse, and rectocele...

INTRODUCTION AND HYPOTHESIS: The objective of this study is to describe pelvic floor muscle function (PFMF) in relation to age and parity in a general female population and to test whether strength/endurance measurements represent all functions of the pelvic floor musculature. METHODS: A cross-sectional study was performed on 95% of the women aged 45-85 years from a small Dutch town. Validated questionnaires were used to obtain general information, and vaginal examination to test PFMF was performed on 649 women...

INTRODUCTION AND HYPOTHESIS: The aim of this study was to assess the relationship between ultrasound estimation of bladder weight (UEBW), symptoms and urodynamic diagnosis. METHODS: Women with lower urinary tract symptoms underwent urodynamics studies and measurement of UEBW at a fixed bladder volume. RESULTS: Women with overactive bladder symptoms had a median UEBW of 48.3 g (95% CI 44-52), with stress urinary incontinence a median UEBW of 35...

INTRODUCTION AND HYPOTHESIS: To confirm the efficacy and tolerability of extended release (ER) trospium chloride in women with overactive bladder syndrome (OAB), data from two identical phase III studies were analyzed. METHODS: Adults (aged > or = 18 years) who had OAB with urinary urgency, frequency, and urge urinary incontinence (UUI) were randomized to trospium ER 60 mg or placebo once daily for 12 weeks. The analysis included 989 women (trospium ER, n = 484; placebo, n = 505)...

INTRODUCTION AND HYPOTHESIS: Aim of this study was to investigate the pattern of the foreign body reaction of macroporous polypropylene mesh (MPPM) used in females for the treatment of stress urinary incontinence and to compare this pattern between eroded and noneroded tapes. METHODS: Ten explanted suburethral slings, five eroded and five noneroded, were examined immunohistochemically under light microscopy; the tissue reaction was compared between eroded and noneroded materials...

INTRODUCTION AND HYPOTHESIS: The objective of the study was to determine urogynecology publication rates in obstetrics and gynecology literature. METHODS: Original scientific articles from American Journal of Obstetrics and Gynecology (AJOG) and Obstetrics and Gynecology (Obstet Gynecol) from 1996-2007 were reviewed. RESULTS: A total of 10,192 articles were evaluated. Two trends were noted in the AJOG: percentage of urogynecology articles increased (correlation with year r = 0...

INTRODUCTION AND HYPOTHESIS: Transabdominal (TA) ultrasound and perineometry have been currently used to assess lifting aspect and squeezing action of pelvic floor muscles (PFM) function, respectively, in women with stress urinary incontinence (SUI). However, no study has directly compared these measurements. The purpose of this study was to investigate the reliability and correlation between perineometry and TA ultrasound as measurements of different aspect of PFM function. METHODS: A total of 28 women with SUI participated in the study...

INTRODUCTION AND HYPOTHESIS: Pelvic floor muscle training (PFMT) is a treatment for stress urinary incontinence (SUI) that can be done individually or in a group. The aim of this study was to compare these two types of treatment. METHODS: Sixty women 30 to 75 years old with SUI were randomly assigned to participate in the two groups. They were evaluated before and after the treatment with the Oxford grading system, pad test, voiding diary, and the King's Health Questionnaire...

INTRODUCTION AND HYPOTHESIS: To quantify the prevalence (previous month) of urinary incontinence (UI) and overactive bladder (OAB), to assess its relation with known risk factors and to characterize UI awareness and treatment. METHODS: Telephone interviews were conducted in 1,934 Portuguese subjects aged > or =40 years. UI was defined according to the International Continence Society definitions. OAB was assessed through the Overactive Bladder Assessment Tool...

INTRODUCTION AND HYPOTHESIS: We assessed whether urinary excretion of glycosaminoglycans (GAGs) may be affected by a condition of detrusor overactivity (DO). MATERIALS AND METHODS: We evaluated 24-h urinary excretion of GAGs in 25 patients (mean age 63.81 years) with DO and in 14 healthy controls (mean age 65.75 years). No patients or controls had urinary tract infection. The excretion of GAGs was measured on the basis of total urine volume and normalized to creatinine concentration...

INTRODUCTION AND HYPOTHESIS: Many physicians in primary care and medical/surgical specialties will care for female patients with pelvic floor disorders (PFD). METHODS: A survey was mailed to 266 United States and Canadian clerkship directors that queried how medical students were being educated in PFD. RESULTS: Forty-four percent of clerkship directors responded. The mean clerkship size was 105 medical students. Over 97% of third year medical students received lectures on hypertension in pregnancy, normal labor, and abnormal uterine bleeding and at least 90% received lectures on obstetric hemorrhage, placenta previa, and menstruation...

INTRODUCTION AND HYPOTHESIS: The National Institute for Health and Clinical Excellence (NICE) recommends antenatal pelvic floor exercises during first pregnancy to reduce postpartum stress incontinence. The aim of this audit was to assess patient awareness and compliance with this guideline. METHODS: An anonymous self-constructed questionnaire was given to patients after their first delivery. RESULTS: A total of 223 questionnaires were returned over a 6-month period...

INTRODUCTION AND HYPOTHESIS: To determine referral patterns to the gynecology directorate for symptomatic pelvic organ prolapse and urinary incontinence METHODS: A prospective multicenter survey of three district general hospitals in Northwest England. Referral letters sent by family physicians to consultants were studied over a three-month period. Main outcome measures were presenting complaints of prolapse and incontinence RESULTS: Two thousand seven hundred sixty-nine referral letters were surveyed...

INTRODUCTION AND HYPOTHESIS: Pelvic organ prolapse and hernia are common disorders which share several pathopysiological and epidemiological features. We therefore aimed to assess whether women with advanced pelvic organ prolapse have a higher prevalence of hernia. METHODS: We reviewed charts of women undergoing surgery for advanced pelvic organ prolapse and compared them to age-matched controls with mild or no prolapse. RESULTS: We identified 60 patients who underwent surgery for advanced pelvic organ prolapse and 60 controls...