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Hong Kong Medical Journal, Xianggang Yi Xue za Zhi

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https://read.qxmd.com/read/30713150/antibiotic-management-of-acute-pharyngitis-in-primary-care
#1
A M W Chan, W W Y Au, D V K Chao, K Choi, K W Choi, S M Y Choi, Y Chow, C Y M Fan, P L Ho, E M T Hui, K H Kwong, B Y S Kwong, T P Lam, E T K Lam, K W Lau, L Lui, K H L Ng, M C S Wong, T Y Wong, C F Yeung, J H S You, R W H Yung
The Centre for Health Protection of the Department of Health has convened the Advisory Group on Antibiotic Stewardship Programme in Primary Care (the Advisory Group) to formulate guidance notes and strategies for optimising judicious use of antibiotics and enhancing the Antibiotic Stewardship Programme in Primary Care. Acute pharyngitis is one of the most common conditions among out-patients in primary care in Hong Kong. Practical recommendations on the diagnosis and antibiotic treatment of acute streptococcal pharyngitis are made by the Advisory Group based on the best available clinical evidence, local prevalence of pathogens and associated antibiotic susceptibility profiles, and common local practice...
January 31, 2019: Hong Kong Medical Journal, Xianggang Yi Xue za Zhi
https://read.qxmd.com/read/30713149/update-on-the-association-between-dry-eye-disease-and-meibomian-gland-dysfunction
#2
REVIEW
T C Y Chan, S S W Chow, K H N Wan, H K L Yuen
Dry eye disease is one of the most common ophthalmic complaints; it results from the activity of various pathways and is considered a multifactorial disease. An important factor that contributes to the onset of dry eye disease is meibomian gland dysfunction. Meibomian gland dysfunction causes a disruption in the tear film lipid layer which affects the rate of tear evaporation. This evaporation leads to tear hyperosmolarity, eventually triggering the onset of dry eye disease. Dry eye disease and meibomian gland dysfunction are strongly associated with each other, such that many of their risk factors, signs, and symptoms overlap...
January 31, 2019: Hong Kong Medical Journal, Xianggang Yi Xue za Zhi
https://read.qxmd.com/read/30670673/sudden-arrhythmia-death-syndrome-in-young-victims-a-five-year-retrospective-review-and-two-year-prospective-molecular-autopsy-study-by-next-generation-sequencing-and-clinical-evaluation-of-their-first-degree-relatives
#3
C M Mak, N S Mok, H C Shum, W K Siu, Y K Chong, H Hc Lee, N C Fong, S F Tong, K W Lee, C K Ching, S Pl Chen, W L Cheung, C B Tso, W M Poon, C L Lau, Y K Lo, P T Tsui, S F Shum, K C Lee
OBJECTIVE: Sudden arrhythmia death syndrome (SADS) accounts for about 30% of causes of sudden cardiac death (SCD) in young people. In Hong Kong, there are scarce data on SADS and a lack of experience in molecular autopsy. We aimed to investigate the value of molecular autopsy techniques for detecting SADS in an East Asian population. METHODS: This was a two-part study. First, we conducted a retrospective 5-year review of autopsies performed in public mortuaries on young SCD victims...
January 23, 2019: Hong Kong Medical Journal, Xianggang Yi Xue za Zhi
https://read.qxmd.com/read/30655461/prevalence-of-chromosomal-abnormalities-and-22q11-2-deletion-in-conotruncal-and-non-conotruncal-antenatally-diagnosed-congenital-heart-diseases-in-a-chinese-population
#4
C W Kong, Y Ky Cheng, W Wk To, T Y Leung
INTRODUCTION: The aim of the present study was to calculate the prevalence of chromosomal abnormalities among antenatally diagnosed congenital heart diseases (CHDs), and the prevalence of 22q11.2 deletion in those with conotruncal CHDs versus isolated non-conotruncal CHDs. METHODS: All patients with antenatal ultrasound finding of fetal CHDs in two obstetric units in a 5-year period were retrospectively reviewed. Detected CHDs were classified as conotruncal if the malformation involved either the aortic outflow tract or the pulmonary outflow tract; otherwise they were classified as non-conotruncal...
January 18, 2019: Hong Kong Medical Journal, Xianggang Yi Xue za Zhi
https://read.qxmd.com/read/30655460/survey-on-prevalence-of-lower-urinary-tract-symptoms-in-an-asian-population
#5
C H Yee, C K Chan, J Yc Teoh, P Kf Chiu, J Hm Wong, E Sy Chan, S Sm Hou, C F Ng
INTRODUCTION: Lower urinary tract symptoms (LUTS) have a strong effect on socio-economic and individual quality of life. The aim of the present study was to investigate the prevalence of LUTS in an Asian population. METHODS: A telephone survey of individuals aged ≥40 years and of Chinese ethnicity was conducted. The survey included basic demographics, medical and health history, drinking habits, International Prostate Symptom Score, overactive bladder symptom score, Patient Health Questionnaire (PHQ-9) score, and Short Form (SF)-12v2 score...
January 18, 2019: Hong Kong Medical Journal, Xianggang Yi Xue za Zhi
https://read.qxmd.com/read/30655459/totally-laparoscopic-versus-open-gastrectomy-for-advanced-gastric-cancer-a-matched-retrospective-cohort-study
#6
B Yo Chan, K Kw Yau, C Ko Chan
INTRODUCTION: Laparoscopic gastrectomy revolutionised the management of gastric cancer, yet its oncologic equivalency and safety in treating advanced gastric cancer (especially that in smaller centres) has remained controversial because of the extensive lymphadenectomy and learning curve involved. This study aimed to compare outcomes following laparoscopic versus open gastrectomy for advanced gastric cancer at a regional institution in Hong Kong. METHODS: Fifty-four patients who underwent laparoscopic gastrectomy from January 2009 to March 2017 were compared with 167 patients who underwent open gastrectomy during the same period...
January 18, 2019: Hong Kong Medical Journal, Xianggang Yi Xue za Zhi
https://read.qxmd.com/read/30643038/percutaneous-mechanical-thrombectomy-in-the-treatment-of-acute-iliofemoral-deep-vein-thrombosis-a-systematic-review
#7
REVIEW
P C Wong, Y C Chan, Y Law, S Wk Cheng
BACKGROUND: Conventional treatment of deep vein thrombosis (DVT) of the lower extremities by anticoagulation alone has been proven to be insufficient to prevent recurrence and post-thrombotic syndrome (PTS). Early restoration of venous patency and preservation of valvular function by endovascular surgery has been advocated. The aim of this study was to review the efficacy and safety of percutaneous mechanical thrombectomy (PMT) against catheter-directed thrombolysis (CDT) in the treatment of acute iliofemoral DVT...
January 11, 2019: Hong Kong Medical Journal, Xianggang Yi Xue za Zhi
https://read.qxmd.com/read/30648830/update-on-the-hong-kong-reference-framework-for-hypertension-care-for-adults-in-primary-care-settings-review-of-evidence-on-the-definition-of-high-blood-pressure-and-goal-of-therapy
#8
M K Lim, S C N Ha, K H Luk, W K Yip, C S H Tsang, M C S Wong
The Hong Kong Reference Framework for Hypertension Care for Adults in Primary Care Settings is updated regularly to ensure it reflects the latest medical development and best practice. In 2017, guidelines from the United States included a major change, adopting the lower blood pressure values of 130/80 mm Hg in defining hypertension, in contrast to the prevailing international consensus of 140/90 mm Hg. After thorough review of the literature and international guidelines, the Advisory Group on Hong Kong Reference Framework for Care of Diabetes and Hypertension in Primary Care Settings (Advisory Group) recommends that the definition of hypertension adopted in the Reference Framework should remain unchanged as a blood pressure of ≥140/90 mm Hg, as there is currently inadequate evidence and lack of general consensus to support such change in Hong Kong...
January 3, 2019: Hong Kong Medical Journal, Xianggang Yi Xue za Zhi
https://read.qxmd.com/read/30602628/title
#9
M K Lim, S Cn Ha, K H Luk, W K Yip, C Sh Tsang, M Cs Wong
The Hong Kong Reference Framework for Hypertension Care for Adults in Primary Care Settings is updated regularly to ensure it reflects the latest medical development and best practice. In 2017, guidelines from the United States included a major change, adopting the lower blood pressure values of 130/80 mm Hg in defining hypertension, in contrast to the prevailing international consensus of 140/90 mm Hg. After thorough review of the literature and international guidelines, the Advisory Group on Hong Kong Reference Framework for Care of Diabetes and Hypertension in Primary Care Settings (Advisory Group) recommends that the definition of hypertension adopted in the Reference Framework should remain unchanged as a blood pressure of ≥140/90 mm Hg, as there is currently inadequate evidence and lack of general consensus to support such change in Hong Kong...
January 3, 2019: Hong Kong Medical Journal, Xianggang Yi Xue za Zhi
https://read.qxmd.com/read/30530869/branded-versus-generic-drug-use-in-chronic-disease-management-in-hong-kong-perspectives-of-health-care-professionals-and-the-general-public
#10
V Wy Lee, F Wt Cheng, F Yh Fong, E En Ng, L Lh Lo, L Ys Ngai, A Sm Lam
INTRODUCTION: The aim of the present study was to evaluate the understanding of generic substitution among health care professionals and members of the general public ("general public") in Hong Kong. METHODS: This cross-sectional descriptive study was performed by using a self-completed anonymous questionnaire from March 2015 to May 2017. The questionnaire included demographic data, knowledge of generic drugs, experiences of generic substitution, and views on policy...
December 3, 2018: Hong Kong Medical Journal, Xianggang Yi Xue za Zhi
https://read.qxmd.com/read/30530868/clinical-and-genetic-profile-of-congenital-long-qt-syndrome-in-hong-kong-a-20-year-experience-in-paediatrics
#11
S Y Kwok, A Py Liu, C Yy Chan, K S Lun, J Lf Fung, C Cy Mak, B Hy Chung, T C Yung
INTRODUCTION: Congenital long QT syndrome (LQTS) is a genetically transmitted cardiac channelopathy that can lead to sudden cardiac death. This study aimed to report the clinical and genetic characteristics of all young patients diagnosed with LQTS in the only tertiary paediatric cardiology centre in Hong Kong. METHODS: This is a retrospective review of all paediatric and young adult patients diagnosed at our centre with LQTS from January 1997 to December 2016. The diagnosis of LQTS was established with a corrected QT interval (QTc) ≥480 ms, Schwartz score of >3 points, or the presence of a pathogenic mutation...
December 3, 2018: Hong Kong Medical Journal, Xianggang Yi Xue za Zhi
https://read.qxmd.com/read/30530867/epidemiology-of-myopia-and-prevention-of-myopia-progression-in-children-in-east-asia-a-review
#12
REVIEW
C Y Mak, J Cs Yam, L J Chen, S M Lee, A L Young
INTRODUCTION: Myopia (short-sightedness) exhibits high prevalence in East Asia. Methods to mitigate myopia progression are important in preventing the vision-threatening complications associated with high myopia. In this review, we examine the regional epidemiology of myopia and provide updated evidence regarding interventions to slow myopia progression in children. METHODS: We performed a literature search using PubMed from the date of inception through 25 June 2018...
December 3, 2018: Hong Kong Medical Journal, Xianggang Yi Xue za Zhi
https://read.qxmd.com/read/30482884/title
#13
REVIEW
T L Poon, C Ht Lui, I Chan, D Yw Siu
Epilepsy is defined as drug-resistant after failure of two adequate trials of appropriately chosen and administered antiepileptic drugs. Approximately 30% of patients with epilepsy have drug-resistant epilepsy. Reasons for treatment failure include failure to recognise epilepsy syndrome, poor drug compliance, and lifestyle factors. Patients with drug-resistant epilepsy should be encouraged to have early referral to a tertiary epilepsy centre for presurgical evaluation. Comprehensive neurophysiology, structural neuroimaging, neuropsychological, and psychiatric assessments are regarded as essential for determining suitability for epilepsy surgery...
November 27, 2018: Hong Kong Medical Journal, Xianggang Yi Xue za Zhi
https://read.qxmd.com/read/30713148/detecting-cognitive-impairment-in-hospitalised-patients-with-acute-heart-failure-using-a-sensitive-tool-does-matter
#14
LETTER
M A Heidari Gorji
No abstract text is available yet for this article.
February 2019: Hong Kong Medical Journal, Xianggang Yi Xue za Zhi
https://read.qxmd.com/read/30713147/bilateral-lumbar-hernia
#15
I Chung, K Y Wong
No abstract text is available yet for this article.
February 2019: Hong Kong Medical Journal, Xianggang Yi Xue za Zhi
https://read.qxmd.com/read/30713146/dynamic-dual-source-computed-tomography-imaging-for-myocardial-perfusion
#16
A Li, Y H Chan, B E Wu, C S Lam
No abstract text is available yet for this article.
February 2019: Hong Kong Medical Journal, Xianggang Yi Xue za Zhi
https://read.qxmd.com/read/30713145/cardiovascular-event-in-chronic-myeloid-leukaemia-treated-with-tyrosine-kinase-inhibitor-a-case-report
#17
Y L Boo, C C K Liam, S Y Lim, M L Look
No abstract text is available yet for this article.
February 2019: Hong Kong Medical Journal, Xianggang Yi Xue za Zhi
https://read.qxmd.com/read/30713144/ciliated-muconodular-papillary-tumour-of-the-lung-mimicking-mucinous-adenocarcinoma-a-case-report-and-literature-review
#18
F M F Cheung, J Guan, Q G Luo, A D L Sihoe, X P Shen
No abstract text is available yet for this article.
February 2019: Hong Kong Medical Journal, Xianggang Yi Xue za Zhi
https://read.qxmd.com/read/30713143/management-of-thigh-lipofibromatosis-in-a-newborn-a-case-report
#19
Y L Lam, W Y Ho, R Yau, V W K Lee, T W H Shek
No abstract text is available yet for this article.
February 2019: Hong Kong Medical Journal, Xianggang Yi Xue za Zhi
https://read.qxmd.com/read/30713142/-healthcare-for-society-a-column-featuring-outstanding-community-contributions
#20
EDITORIAL
M C S Wong, E C H Lai
No abstract text is available yet for this article.
February 2019: Hong Kong Medical Journal, Xianggang Yi Xue za Zhi
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