journal
https://read.qxmd.com/read/38457529/reply-to-beyond-discrimination-a-call-for-comprehensive-assessment-of-clinical-prediction-models-in-inflammatory-bowel-disease
#41
EDITORIAL
Daniel Famutimi, Quazim A Alayo, Parakkal Deepak
No abstract text is available yet for this article.
March 8, 2024: Inflammatory Bowel Diseases
https://read.qxmd.com/read/38457489/antibacterial-agents-may-have-shifted-impacts-on-inflammatory-bowel-diseases-along-with-decrease-in-gut-bacteria
#42
JOURNAL ARTICLE
Xiaofa Qin
No abstract text is available yet for this article.
March 8, 2024: Inflammatory Bowel Diseases
https://read.qxmd.com/read/38452040/ai-luminating-artificial-intelligence-in-inflammatory-bowel-diseases-a-narrative-review-on-the-role-of-ai-in-endoscopy-histology-and-imaging-for-ibd
#43
JOURNAL ARTICLE
Phillip Gu, Oreen Mendonca, Dan Carter, Shishir Dube, Paul Wang, Xiuzhen Huang, Debiao Li, Jason H Moore, Dermot P B McGovern
Endoscopy, histology, and cross-sectional imaging serve as fundamental pillars in the detection, monitoring, and prognostication of inflammatory bowel disease (IBD). However, interpretation of these studies often relies on subjective human judgment, which can lead to delays, intra- and interobserver variability, and potential diagnostic discrepancies. With the rising incidence of IBD globally coupled with the exponential digitization of these data, there is a growing demand for innovative approaches to streamline diagnosis and elevate clinical decision-making...
March 7, 2024: Inflammatory Bowel Diseases
https://read.qxmd.com/read/38452032/the-long-view-2-year-outcomes-of-mirikizumab-for-ulcerative-colitis
#44
JOURNAL ARTICLE
Lushen Pillay, Sreedhar Subramanian
No abstract text is available yet for this article.
March 7, 2024: Inflammatory Bowel Diseases
https://read.qxmd.com/read/38452029/dietary-interventions-and-supplementation-in-patients-with-an-ileal-pouch-anal-anastomosis-a-systematic-review
#45
JOURNAL ARTICLE
Stephanie Gold, Carrie Levinson, Jean-Frederic Colombel, Laura Manning, Bruce E Sands, Maia Kayal
No abstract text is available yet for this article.
March 7, 2024: Inflammatory Bowel Diseases
https://read.qxmd.com/read/38442897/reply-interleukin-18-inhibition-in-inflammatory-bowel-diseases-a-delicate-balance
#46
EDITORIAL
Keiko Maeda, Hiroki Kawashima
No abstract text is available yet for this article.
March 5, 2024: Inflammatory Bowel Diseases
https://read.qxmd.com/read/38442894/interleukin-18-inhibition-in-inflammatory-bowel-disease-a-delicate-balance
#47
EDITORIAL
Sem Geertsema, Raphael R Fagundes, Antonius T Otten, Gerard Dijkstra, Klaas Nico Faber, Arno R Bourgonje
No abstract text is available yet for this article.
March 5, 2024: Inflammatory Bowel Diseases
https://read.qxmd.com/read/38439613/inflammatory-bowel-disease-and-breastfeeding-a-narrative-review
#48
JOURNAL ARTICLE
Tedi Hoxha, Michael Youssef, Vivian Huang, Parul Tandon
Inflammatory bowel disease (IBD) frequently affects women of childbearing age who may consider breastfeeding. Although breastfeeding has numerous benefits, there remain concerns regarding the safety of breastfeeding among women with IBD. Breastfeeding is important in developing the immune system of infants and has been shown to protect against the development of IBD. The risk of developing an increase in disease activity postpartum is the same regardless of breastfeeding status. Most IBD medications are also considered safe in breastfeeding and have no major risks to infants...
March 4, 2024: Inflammatory Bowel Diseases
https://read.qxmd.com/read/38431309/toldc-restores-the-balance-of-th17-treg-via-aryl-hydrocarbon-receptor-to-attenuate-colitis
#49
JOURNAL ARTICLE
Shu Wang, Ying Xu, Lu Wang, Junjie Lin, Chenjing Xu, Xiaojing Zhao, Hongjie Zhang
BACKGROUND: Tolerogenic dendritic cells (TolDCs) have been evidenced to trigger regulatory T cell's (Treg's) differentiation and be involved in the pathogenesis of Crohn's disease (CD). Aryl hydrocarbon receptor (AhR) plays a crucial role in the differentiation of TolDCs, although the mechanism remains vague. This study aimed to evaluate the role of AhR in TolDCs formation, which may affect Th17/Treg balance in CD. METHODS: Colon biopsy specimens were obtained from healthy controls and patients with CD...
March 2, 2024: Inflammatory Bowel Diseases
https://read.qxmd.com/read/38427714/risk-of-infection-in-patients-with-inflammatory-bowel-disease-treated-with-interleukin-targeting-agents-a-systematic-review-and-meta-analysis
#50
JOURNAL ARTICLE
Konstantinos Ouranos, Hira Saleem, Stephanos Vassilopoulos, Athanasios Vassilopoulos, Evangelia K Mylona, Fadi Shehadeh, Markos Kalligeros, Bincy P Abraham, Eleftherios Mylonakis
BACKGROUND: Patients with inflammatory bowel disease (IBD) are at increased risk of infection. The aim of this study was to assess the cumulative incidence and risk of infection in patients with IBD treated with interleukin (IL)-targeting agents. METHODS: We searched PubMed, EMBASE, and Web of Science for randomized controlled trials including patients with IBD receiving IL-targeting agents compared with patients receiving placebo or treatment that only differed from the intervention arm in the absence of an IL-targeting agent...
March 1, 2024: Inflammatory Bowel Diseases
https://read.qxmd.com/read/38427713/feasibility-and-acceptability-of-digital-behavioral-interventions-among-black-and-hispanic-patients-with-inflammatory-bowel-disease-a-randomized-pilot-study
#51
JOURNAL ARTICLE
Ruby Greywoode, Shadi Nahvi, Thomas Ullman, Laurie Keefer
No abstract text is available yet for this article.
March 1, 2024: Inflammatory Bowel Diseases
https://read.qxmd.com/read/38422244/2-hydroxycinnamaldehyde-alleviates-intestinal-inflammation-by-attenuating-intestinal-mucosal-barrier-damage-via-directly-inhibiting-stat3
#52
JOURNAL ARTICLE
Meilin Chen, Shuchun Wei, Xiaohan Wu, Zixuan Xiang, Xiangyun Li, Haodong He, Fei Liao, Xiaoli Wang, Jixiang Zhang, Baoping Yu, Weiguo Dong
BACKGROUND: The currently available clinical therapeutic drugs for ulcerative colitis (UC) are considered inadequate owing to certain limitations. There have been reports on the anti-inflammatory effects of 2'-hydroxycinnamaldehyde (HCA). However, whether HCA can improve UC is still unclear. Here, we aimed to investigate the pharmacological effects of HCA on UC and its underlying molecular mechanisms. METHODS: The pharmacological effects of HCA were comprehensively investigated in 2 experimental setups: mice with dextran sulfate sodium (DSS)-induced colitis and lipopolysaccharide (LPS)-treated fetal human colon (FHC) cells...
February 29, 2024: Inflammatory Bowel Diseases
https://read.qxmd.com/read/38417068/comparison-of-fecal-calprotectin-and-myeloperoxidase-in-predicting-outcomes-in-inflammatory-bowel-disease
#53
JOURNAL ARTICLE
A Swaminathan, G M Borichevsky, C M Frampton, A S Day, M B Hampton, A J Kettle, R B Gearry
BACKGROUND: Biomarkers have been proposed as surrogate treatment targets for the management of inflammatory bowel disease (IBD); however, their relationship with IBD-related complications remains unclear. This study investigated the utility of neutrophil biomarkers fecal calprotectin (fCal) and fecal myeloperoxidase (fMPO) in predicting a complicated IBD course. METHODS: Participants with IBD were followed for 24 months to assess for a complicated IBD course (incident corticosteroid use, medication escalation for clinical disease relapse, IBD-related hospitalizations/surgeries)...
February 28, 2024: Inflammatory Bowel Diseases
https://read.qxmd.com/read/38417051/our-life-is-a-rollercoaster-a-qualitative-phenomenological-study-exploring-the-impact-of-ibd-on-family-members
#54
JOURNAL ARTICLE
Parichat Thapwong, Christine Norton, Emma Rowland, Wladyslawa Czuber-Dochan
BACKGROUND: Inflammatory bowel disease (IBD) significantly impacts patients and their families. To provide support, understanding the effects on the wider family is crucial. However, limited research exists on the impact of IBD on family members of adults diagnosed with IBD. This study addresses this knowledge gap. METHODS: Underpinned by interpretive phenomenology, this study used in-depth, semi-structured online interviews to explore relatives' experiences. Interviews were audio-recorded and transcribed verbatim...
February 28, 2024: Inflammatory Bowel Diseases
https://read.qxmd.com/read/38412344/comorbidity-between-inflammatory-bowel-disease-and-asthma-and-allergic-diseases-a-genetically-informed-study
#55
JOURNAL ARTICLE
Tong Gong, Bronwyn K Brew, Cecilia Lundholm, Awad I Smew, Arvid Harder, Ralf Kuja-Halkola, Jonas F Ludvigsson, Yi Lu, Catarina Almqvist
BACKGROUND: Little is known about shared origins between inflammatory bowel disease (IBD) and allergic diseases (asthma, allergic rhinitis, and eczema). We aimed to expand current knowledge on the etiological sources of comorbidities between these disorders using a range of genetically informed methods. METHODS: Within-individual and familial co-aggregation analysis was applied to 2 873 445 individuals born in Sweden from 1987 to 2014 and their first- and second-degree relatives...
February 27, 2024: Inflammatory Bowel Diseases
https://read.qxmd.com/read/38408096/clinical-outcomes-at-8-16-weeks-after-upadacitinib-initiation-for-acute-severe-ulcerative-colitis-a-case-series-in-the-united-states
#56
JOURNAL ARTICLE
Rahul S Dalal, Rachel W Winter, Sanchit Gupta, Gila F Sasson, Matthew J Hamilton, Jessica R Allegretti
No abstract text is available yet for this article.
February 26, 2024: Inflammatory Bowel Diseases
https://read.qxmd.com/read/38408068/causal-association-analysis-of-periodontitis-and-inflammatory-bowel-disease-a-bidirectional-mendelian-randomization-study
#57
JOURNAL ARTICLE
Xiangli Qing, Chenhui Zhang, Zhuotai Zhong, Tao Zhang, Lin Wang, Shuangshuang Fang, Tianyuan Jiang, Xiaoying Luo, Yang Yang, Gengqing Song, Wei Wei
BACKGROUND: Periodontitis has been reported to be associated with inflammatory bowel disease (IBD), including ulcerative colitis (UC), and Crohn's disease (CD). However, the causality of these 2 diseases remains unclear. We conducted bidirectional Mendelian randomization (MR) to investigate the causal relationship between periodontitis and IBD. METHODS: We obtained the genome-wide association study (GWAS) summary data of European populations from FinnGen database (for IBD) and a published article (for periodontitis), from which independent single nucleotide polymorphisms were selected as instrumental variables...
February 26, 2024: Inflammatory Bowel Diseases
https://read.qxmd.com/read/38401568/surgical-complications-need-to-be-carefully-excluded-before-ruling-out-a-diagnosis-of-de-novo-crohn-s-disease
#58
EDITORIAL
Massimo Martinelli, Erasmo Miele, Annamaria Staiano
No abstract text is available yet for this article.
February 24, 2024: Inflammatory Bowel Diseases
https://read.qxmd.com/read/38387614/response-to-de-novo-crohn-s-disease-in-children-with-ulcerative-colitis-undergoing-ileal-pouch-anal-anastomosis-a-multicenter-retrospective-study-from-the-pediatric-ibd-porto-group-of-the-espghan
#59
EDITORIAL
Djuna de Jong, Maud Reijntjes, Christianne Buskens, Roel Hompes, Geert D'Haens, Willem Bemelman, Marjolijn Duijvestein
No abstract text is available yet for this article.
February 22, 2024: Inflammatory Bowel Diseases
https://read.qxmd.com/read/38372691/sustained-increase-in-pediatric-inflammatory-bowel-disease-incidence-across-the-south-west-united-kingdom-over-the-last-10-years
#60
JOURNAL ARTICLE
Zachary Green, James J Ashton, Astor Rodrigues, Christine Spray, Lucy Howarth, Akshatha Mallikarjuna, Neil Chanchlani, James Hart, Christopher Bakewell, Kwang Yang Lee, Amar Wahid, R Mark Beattie
BACKGROUND: Pediatric inflammatory bowel disease (pIBD) incidence has increased over the last 25 years. We aim to report contemporaneous trends across the South West United Kingdom. METHODS: Data were provided from centers covering the South West United Kingdom (Bristol, Oxford, Cardiff, Exeter, and Southampton), with a total area at-risk population (<18 years of age) of 2 947 534. Cases were retrieved from 2013 to 2022. Incident rates were reported per 100 000 at-risk population, with temporal trends analyzed through correlation...
February 19, 2024: Inflammatory Bowel Diseases
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