Rotem Sigall Boneh, Catherine Westoby, Ilan Oseran, Chen Sarbagili-Shabat, Lindsey G Albenberg, Paolo Lionetti, Víctor Manuel Navas-López, Javier Martín-de-Carpi, Henit Yanai, Nitsan Maharshak, Johan Van Limbergen, Eytan Wine
Dietary therapy is increasingly recognized for the management of Crohn's disease (CD) over recent years, including the use of exclusive enteral nutrition (EEN) as first-line therapy for pediatric CD according to current guidelines. The Crohn's disease exclusion diet (CDED) is a whole-food diet designed to reduce exposure to dietary components that are potentially pro-inflammatory, mediated by negative effects on the gut microbiota, immune response, and the intestinal barrier. The CDED has emerged as a valid alternative to EEN with cumulative evidence, including randomized controlled trials, supporting use for induction of remission and possibly maintenance in children and adults...
November 18, 2023: Inflammatory Bowel Diseases