journal
Journals Clinical and Applied Thrombosi...

Clinical and Applied Thrombosis/hemostasis

https://read.qxmd.com/read/38377679/immature-platelet-fraction-and-clinical-outcomes-in-patients-undergoing-transcatheter-aortic-valve-implantation
#1
JOURNAL ARTICLE
Lee Oppenheim, Ranel Loutati, David Marmor, Nimrod Perel, Meir Tabi, Louay Taha, Danny Dvir, Mony Shuvy, Rami Jubeh, Michael Glikson, Elad Asher
INTRODUCTION: Immature platelets or reticulated platelets are newly released thrombocytes. They can be identified by their large size and high RNA cytoplasm concentration. Immature platelet fraction (IPF) represents the percentage of immature circulative platelets relative to the total number of platelets. The role of IPF in patients undergoing transcatheter aortic valve implantation (TAVI) is unknown. The aim of the current trial was to assess the levels of IPF in patients undergoing TAVI and correlation with clinical outcomes...
2024: Clinical and Applied Thrombosis/hemostasis
https://read.qxmd.com/read/38377673/development-and-validation-of-a-nomogram-for-predicting-the-severity-of-coronary-artery-disease-based-on-cardiopulmonary-exercise-testing
#2
JOURNAL ARTICLE
Hongmin Wang, Yi Wang, Qingmin Wei, Liyan Zhao, Qingjuan Zhang
As a major global health concern, coronary artery disease (CAD) demands precise, noninvasive diagnostic methods like cardiopulmonary exercise testing (CPET) for effective assessment and management, balancing the need for accurate disease severity evaluation with improved treatment decision-making. Our objective was to develop and validate a nomogram based on CPET parameters for noninvasively predicting the severity of CAD, thereby assisting clinicians in more effectively assessing patient conditions. This study analyzed 525 patients divided into training (367) and validation (183) cohorts, identifying key CAD severity indicators using least absolute shrinkage and selection operator (LASSO) regression...
2024: Clinical and Applied Thrombosis/hemostasis
https://read.qxmd.com/read/38348584/evaluation-of-hemogram-parameters-in-the-diagnosis-of-pulmonary-embolism-immature-granulocytes-and-other-new-tips
#3
JOURNAL ARTICLE
Gokhan Karakurt, Oya Guven, Engin Aynaci, Bugra Kerget, Gizem Senkardesler, Mustafa Duger
Pulmonary embolism (PE) is an important cause of sudden death and is difficult to diagnose. Therefore unnecessary radiological investigations are often resorted to. Although some inflammatory parameters in the hemogram have been found to play a role in the diagnosis of PE, many parameters have not been adequately investigated. We aimed to evaluate potential inflammatory parameters in hemogram in the diagnosis of PE and to determine the parameters with the highest diagnostic value. This single-center, retrospective study was performed by evaluating 114 cases with suspected PE admitted to the emergency department between January 2017 and June 2022...
2024: Clinical and Applied Thrombosis/hemostasis
https://read.qxmd.com/read/38327150/investigating-the-impact-on-long-term-outcomes-and-the-necessity-of-hereditary-thrombophilia-screening-in-presumed-or-perinatal-arterial-ischemic-stroke
#4
JOURNAL ARTICLE
Ömer Bektaş, Özben Akıncı Göktaş, Begüm Atasay, Serap Teber
This study aimed to investigate the influence of prothrombotic risk factors on long-term outcomes of patients with perinatal arterial ischemic stroke. The study was conducted through an analysis of monitoring results that were regularly maintained for approximately 20 years at a tertiary stroke-monitoring center. The study assessed prothrombotic risk factors, radiological area of involvement, clinical presentation, treatments, clinical outcomes, and long-term outcomes of the 48 patients included in the study, with a mean monitoring time of 77...
2024: Clinical and Applied Thrombosis/hemostasis
https://read.qxmd.com/read/38321776/coagulation-testing-in-real-world-setting-insights-from-a-comprehensive-survey
#5
JOURNAL ARTICLE
Hae In Bang, Ja Young Lee, Hyun-Young Kim, Saeam Shin, Myung Hyun Nam, In-Suk Kim, Ji Myung Kim, Jong-Hyun Yoon, Myung-Geun Shin, Sang Mee Hwang, Sun-Young Kong
The objective of this survey was to gain a real-world perspective on coagulation testing by evaluating the availability of various coagulation laboratory tests, assessing specific analytic and postanalytic steps in clinical laboratories in Korea.Participants were surveyed using a 65-question questionnaire specifically focused on their coagulation testing practices related to prothrombin time (PT), activated partial thromboplastin time (aPTT), plasma-mixing studies, lupus anticoagulant (LA) tests, platelet function tests, coagulation factor assays, and the composition of hemostasis and thrombosis test panels...
2024: Clinical and Applied Thrombosis/hemostasis
https://read.qxmd.com/read/38238986/the-role-of-hatch-score-in-the-prediction-of-ischemic-cerebrovascular-events-in-patients-with-heart-failure-and-atrial-fibrillation
#6
JOURNAL ARTICLE
Sidar Şiyar Aydın, Emrah Aksakal
The presence of both atrial fibrillation (AF) and heart failure (HF) increases the risk of an ischemic cerebrovascular event (CVE) by roughly fivefold. The HATCH score is a score used to predict new-onset AF. Although there are some differences, it contains risk factors similar to the CHA2DS2-VASc score. Our study aimed to investigate the relationship between the HATCH score and ischemic CVE. This retrospective study obtained data from 1719 HF patients between 2015 and 2022. About 673 patients with AF were included in the study...
2024: Clinical and Applied Thrombosis/hemostasis
https://read.qxmd.com/read/38225166/determination-of-vwf-adamts-13-and-thrombospondin-1-in-venous-thromboembolism-and-relating-them-to-the-presence-of-factor-v-leiden-mutation
#7
JOURNAL ARTICLE
Anwar Al-Awadhi, Rajaa Marouf, Mehrez M Jadaon, Mohammad M Al-Awadhy
Thrombophilia in venous thromboembolism (VTE) is multifactorial. Von Willebrand factor (vWF) plays a major role in primary hemostasis. While elevated vWF levels are well documented in VTE, findings related to its cleaving protease (ADAMTS-13) are contradicting. The aim of this study was to determine vWF, ADAMTS-13, and the multifactorial Thrombospondin-1 (TSP-1) protein levels in patients after 3-6 months following an unprovoked VTE episode. We also explored a possible association with factor V Leiden (FVL) mutation...
2024: Clinical and Applied Thrombosis/hemostasis
https://read.qxmd.com/read/38213124/clinical-outcomes-at-3-years-after-stenting-for-thrombotic-and-non-thrombotic-iliac-vein-compression-syndrome-patients
#8
JOURNAL ARTICLE
Lei Jiang, Hao Zhuang, Tao Song, Xiao-Qiang Li
Iliac vein stenting for the treatment of iliac vein compression syndrome (IVCS) has been gradually developed. This article investigated the long-term patency and improvement of clinical symptoms after endovascular stenting for iliac vein obstruction patients. From 2020 to 2022, 83 patients at a single institution with IVCS underwent venous stent implantation and were divided into two groups: non-thrombotic IVCS ( n  = 55) and thrombotic IVCS ( n  = 28). The main stent-related outcomes include technical success, long-term patency, and thrombotic events...
2024: Clinical and Applied Thrombosis/hemostasis
https://read.qxmd.com/read/38196194/cardiac-arrest-associated-coagulopathy-could-predict-30-day-mortality-a-retrospective-study-from-medical-information-mart-for-intensive-care-iv-database
#9
JOURNAL ARTICLE
Jingwei Duan, Hongxia Ge, Wenyang Fan, Lanfang Du, Hua Zhang, Ayijiang Jiamaliding, Baomin Duan, Qingbian Ma
BACKGROUND: Cardiac arrest (CA) can activate the coagulation system. Some coagulation-related indicators are associated with clinical outcomes. Early evaluation of patients with cardiac arrest-associated coagulopathy (CAAC) not only predicts clinical outcomes, but also allows for timely clinical intervention to prevent disseminated intravascular coagulation. OBJECTIVE: To assess whether CAAC predicts 30-day cumulative mortality. METHODS: From the Medical Information Mart for Intensive Care IV (MIMIC-IV) database, we conducted a retrospective cohort study from 2008 to 2019...
2024: Clinical and Applied Thrombosis/hemostasis
https://read.qxmd.com/read/38173351/treatment-patterns-and-healthcare-resource-utilization-of-patients-with-paroxysmal-nocturnal-hemoglobinuria-a-retrospective-claims-data-analysis
#10
JOURNAL ARTICLE
Denise Clayton, Jason Shafrin, Glorian Yen, Soyon Lee, Lincy Geevarghese, Yulin Shi, Luyang He, Ying Shen, Anem Waheed
Paroxysmal nocturnal hemoglobinuria (PNH) is a rare, acquired hematologic disorder commonly treated with complement inhibitors such as eculizumab, ravulizumab, and pegcetacoplan. This study aims to describe treatment patterns, healthcare resource utilization, and cost for newly diagnosed PNH patients in 2 large, health insurance claims databases: MarketScan and Optum. Among the 271 patients meeting the inclusion criteria in MarketScan, 57.9% were female, and the average age was 46.6 years. Among these newly diagnosed patients, 25...
2024: Clinical and Applied Thrombosis/hemostasis
https://read.qxmd.com/read/38173275/thrombotic-risk-and-calculated-whole-blood-viscosity-in-a-cohort-of-patients-with-new-diagnosis-of-multiple-myeloma
#11
JOURNAL ARTICLE
Melania Carlisi, Rosalia Lo Presti, Salvatrice Mancuso, Sergio Siragusa, Gregorio Caimi
The pathogenesis of venous thromboembolism in multiple myeloma is still poorly understood because multiple factors are involved. In particular, the increase in whole blood viscosity has a key role and, therefore, we performed an evaluation of some hemorheological determinants in multiple myeloma patients, putting them in relation to the thrombotic risk, with the aim to evaluate if an alteration of the hemorheological pattern was associated with a higher thrombotic risk. We performed an observational retrospective cohort study with data collected from January 2017 to September 2022...
2024: Clinical and Applied Thrombosis/hemostasis
https://read.qxmd.com/read/38166474/emicizumab-prophylaxis-in-patients-with-severe-hemophilia-a-insights-from-a-resource-limited-country
#12
JOURNAL ARTICLE
Munira Borhany, Aisha Arshad, Heeba Qureshi, Rukhshanda Nadeem, Arif Jamal, Raheel Ahmed Khan
METHODS: In this prospective study, severe HA patients were recruited from January 2022 to June 2023. Inhibitor positive and inhibitor negative patients with annual bleeding rate (ABR) 8 or greater and past histories of bleeding like intra-cranial, intra-abdominal, and pseudo-tumors were included. Emicizumab loading dose was 3 mg/kg in the first 4 weeks, and the maintenance dose was started at week 5 at 6 mg/kg/month. Patients' detailed bleeding history and demographics were recorded...
2024: Clinical and Applied Thrombosis/hemostasis
https://read.qxmd.com/read/38166421/predictive-value-of-pulmonary-artery-distensibility-for-short-term-adverse-clinical-outcomes-in-patients-with-acute-pulmonary-embolism
#13
JOURNAL ARTICLE
Fei Yang, Rong Chen, Yue Yang, Yaxi Yu, Zhixiang Yang, Dianjun Zou, Zhiying Pang, Dawei Wang
We aimed to explore the relationship between pulmonary artery distensibility obtained from computed tomography pulmonary angiography (CTPA) and short-term adverse clinical outcomes in patients with acute pulmonary embolism (APE). We included patients who underwent retrospective electrocardiogram-gated CTPA and were subsequently diagnosed with APE. Patients were categorized into good and poor outcome groups based on short-term clinical outcomes. Pulmonary artery distensibility (AD), right ventricle/left ventricle (RV/LV) ratio, and pulmonary artery obstruction index (PAOI) were measured, and the receiver operating characteristic curves were constructed...
2024: Clinical and Applied Thrombosis/hemostasis
https://read.qxmd.com/read/38166411/predictive-role-of-pre-thrombolytic-neutrophil-platelet-ratio-on-hemorrhagic-transformation-after-intravenous-thrombolysis-in-acute-ischemic-stroke
#14
JOURNAL ARTICLE
Xu-Dong Cheng, Chun-Xi Zhang, Qi Zhang, Sen Zhou, Li-Jun Jia, Li-Rong Wang, Jian-Hong Wang, Neng-Wei Yu, Bing-Hu Li
To investigate the predictive role of the neutrophil-platelet ratio (NPR) before intravenous thrombolysis (IVT) on hemorrhagic transformation (HT) in patients with acute ischemic stroke (AIS). AIS patients treated with IVT without endovascular therapy between June 2019 and February 2023 were included. Patients were divided into high NPR (>35) and low NPR (≤35) groups according to the optimal threshold NPR value for identifying high-risk patients before IVT. The baseline data and the incidence of HT and symptomatic intracranial hemorrhage (sICH) were compared between the two groups...
2024: Clinical and Applied Thrombosis/hemostasis
https://read.qxmd.com/read/38166398/efficacy-and-safety-of-a-pharmaco-invasive-strategy-using-half-dose-recombinant-human-prourokinase-in-patients-with-st-segment-elevation-myocardial-infarction-during-hospitalization
#15
JOURNAL ARTICLE
Jie Dou, Jie Gao, Huihui Yang, Ruoling Guo, Chao Jiang, Jingtao Guo, Donglei Luo
This study investigated the efficacy and safety of pharmaco-invasive strategy with half-dose recombinant human prourokinase (PHDP) during hospitalization for patients with ST-segment elevation myocardial infarction (STEMI) to provide references for the treatment of STEMI. Patients with STEMI who fulfilled the inclusion and exclusion criteria and attended Chengde Central Hospital, Hebei Province, China, between September 3, 2019, and December 28, 2021, were included in this study. The experimental group received PHDP and the control group underwent primary percutaneous coronary intervention (PPCI)...
2024: Clinical and Applied Thrombosis/hemostasis
https://read.qxmd.com/read/38145624/pharmaco-invasive-therapy-a-continued-role-for-fibrinolysis-in-the-primary-pci-era
#16
JOURNAL ARTICLE
Salma Bouyaddid, Amine Bouchlarhem, Zakaria Bazid, Nabila Ismaili, Noha El Ouafi
INTRODUCTION: Early Primary percutaneous coronary intervention (pPCI) is the preferred reperfusion therapy for most patients with ST-segment elevation myocardial infarction (STEMI), and the European guidelines recommend pPCI to occur within 120 min of first medical contact. However, this is not always available. METHODS: We performed a retrospective study of patients admitted for STEMI to a level I cardiac intensive care unit in a developing country, to analyze the efficacy of the pharmaco-invasive (PI) strategy versus late PCI over a 2-year follow-up...
2023: Clinical and Applied Thrombosis/hemostasis
https://read.qxmd.com/read/38130118/application-of-femoral-nerve-block-in-treating-great-saphenous-vein-insufficiency-by-endovenous-radiofrequency-ablation-combined-with-punctate-stripping
#17
JOURNAL ARTICLE
Ying-Hao Li, Tao Wang, Cheng Qian, Guo-Ping Chen, Wen-Sheng Lou, Jian-Ping Gu
PURPOSE: To evaluate the efficacy and safety of ultrasound-guided femoral nerve block (FNB) in treating great saphenous vein (GSV) insufficiency by endovenous radiofrequency ablation (EVRA) combined with punctate stripping (PS). METHODS: This was a single-center, retrospective cohort study. A total of 135 patients were divided into Group A (59 patients) and Group B (76 patients). All patients received tumescent anesthesia during the operation, and group A received an additional ultrasound-guided FNB before the procedure...
2023: Clinical and Applied Thrombosis/hemostasis
https://read.qxmd.com/read/38126337/sepsis-induced-coagulopathy-the-different-prognosis-in-severe-pneumonia-and-bacteremia-infection-patients
#18
JOURNAL ARTICLE
Rong Liufu, Yan Chen, Xi-Xi Wan, Rui-Ting Liu, Wei Jiang, ChYao Wang, Jin-Min Peng, Li Weng, Bin Du
Sepsis-induced coagulopathy (SIC) is a critical condition in sepsis patients, with varying outcomes depending on the type of infection. This study aims to analyze the prognosis of different infections in SIC cohort. A retrospective cohort study was conducted on 525 patients diagnosed with SIC in the intensive care unit from December 2013 to December 2022. These patients were divided into four groups: a non-pneumonia or bacteremia group, a severe pneumonia group, a bacteremia group, and a severe pneumonia concomitant with bacteremia group...
2023: Clinical and Applied Thrombosis/hemostasis
https://read.qxmd.com/read/38115694/machine-learning-models-for-predicting-early-neurological-deterioration-and-risk-classification-of-acute-ischemic-stroke
#19
JOURNAL ARTICLE
Huan Yang, Zhe Lv, Wenxi Wang, Yaohui Wang, Jie Chen, Zhanqiu Wang
This study aimed to create machine learning models for predicting early neurological deterioration and risk classification in acute ischemic stroke (AIS) before intravenous thrombolysis (IVT). The study included 704 AIS patients categorized into END and non-END groups. The least absolute shrinkage and selection operator (LASSO) regression was employed to select the best predictors from clinical indicators, leading to the creation of Model 1. Univariate and multivariate logistic regression analyses identified independent predictive factors for END from inflammatory cell ratios...
2023: Clinical and Applied Thrombosis/hemostasis
https://read.qxmd.com/read/38115686/evaluation-of-the-safety-and-effectiveness-of-topical-intrapleural-application-of-tranexamic-acid-in-thoracic-surgery-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#20
JOURNAL ARTICLE
Amer Alzahrani, Hadeel Alkofide, Hala Joharji, Ghazwa B Korayem, Sarah Aljohani, Hanan Alshareef, Mashael AlFaifi, Hassan Alalawi, Khalid Al Sulaiman
OBJECTIVES: Bleeding remains a common complication post-thoracic surgery. Although intravenous tranexamic acid (TXA) has been shown to decrease blood loss, its use has been associated with adverse effects. Accordingly, topical TXA has been proposed as an alternative to reduce bleeding with fewer systemic complications. METHODS: We searched Medline, Embase, and Cochrane Central databases for randomized controlled trials (RCTs) comparing topical TXA versus control (i...
2023: Clinical and Applied Thrombosis/hemostasis
journal
journal
32273
1
2
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.