Hangang Chen, Yangli Xie, Mei Zhang, Junlan Huang, Wanling Jiang, Ruobin Zhang, Can Li, Xiaolan Du, Hua Chen, Qiang Nie, Sen Liang, Qiaoyan Tan, Jing Yang, Min Jin, Shuo Huang, Liang Kuang, Nan Su, Huabing Qi, Xiaoqing Luo, Xiaoling Xu, Chuxia Deng, Lin Chen, Fengtao Luo
Physical therapy is extensively employed in clinical settings. Nevertheless, the absence of suitable animal models has resulted in an incomplete understanding of the in vivo mechanisms and cellular distribution that respond to physical stimuli. The objective of this research was to create a mouse model capable of indicating the cells affected by physical stimuli. In this study, we successfully established a mouse line based on the heat shock protein 70 (Hsp70) promoter, wherein the expression of CreERT2 can be induced by physical stimuli...
March 16, 2024: Journal of Molecular Medicine: Official Organ of the "Gesellschaft Deutscher Naturforscher und Ärzte"