Zhouxian Pan, Yimin Dai, Nicole Akar-Ghibril, Jessica Simpson, Huali Ren, Lishan Zhang, Yibo Hou, Xueyi Wen, Christopher Chang, Rui Tang, Jin-Lyu Sun
Air pollution is associated with multiple health problems worldwide, contributing to increased morbidity and mortality. Atopic dermatitis (AD) is a common allergic disease, and increasing evidence has revealed a role of air pollution in the development of atopic dermatitis. Air pollutants are derived from several sources, including harmful gases such as nitrogen dioxide (NO2 ), sulfur dioxide (SO2 ), and carbon monoxide (CO), as well as particulate matter (PM) of various sizes, and bioaerosols. Possible mechanisms linking air pollution to atopic dermatitis include damage to the skin barrier through oxidative stress, increased water loss, physicochemical injury, and an effect on skin microflora...
February 28, 2023: Clinical Reviews in Allergy & Immunology