journal
Journals Current Opinion in Pulmonary M...

Current Opinion in Pulmonary Medicine

https://read.qxmd.com/read/36928032/the-association-of-preexisting-severe-asthma-with-covid-19-outcomes
#1
JOURNAL ARTICLE
Paul D Terry, R Eric Heidel, Rajiv Dhand
PURPOSE OF REVIEW: Three years after the emergence of coronavirus disease 2019 (COVID-19), many studies have examined the association between asthma and COVID-related morbidity and mortality, with most showing that asthma does not increase risk. However, the U.S. Centers for Disease Control (CDC) currently suggests that patients with severe asthma may, nonetheless, be particularly vulnerable to COVID-19-related morbidity. RECENT FINDINGS: With respect to poor COVID-19 outcomes, our search yielded nine studies that quantified associations with severe asthma, seven that considered use of monoclonal antibodies (mAB), and 14 that considered inhaled corticosteroids (ICS) use...
March 20, 2023: Current Opinion in Pulmonary Medicine
https://read.qxmd.com/read/36917228/drug-treatment-of-covid-19-infection
#2
JOURNAL ARTICLE
Grace Lui, Giovanni Guaraldi
PURPOSE OF REVIEW: COVID-19 pandemic has caused more than 6.6 million deaths globally. Tremendous efforts have been committed for the development of new and repurposed drugs for the treatment of COVID-19. Although different international and national guidelines share consensus in the management of COVID-19 disease with different levels of severity, new challenges have emerged, steering the need for ongoing research in advancing the clinical management of COVID-19. RECENT FINDINGS: This review focuses on recent data from randomized trials and postmarketing real-world evidence for the treatment of mild to moderate disease in the outpatient setting and patients hospitalized for COVID-19 with varying level of severity...
March 15, 2023: Current Opinion in Pulmonary Medicine
https://read.qxmd.com/read/36917219/gram-negative-pulmonary-infections-advances-in-epidemiology-and-diagnosis
#3
JOURNAL ARTICLE
Mihaela Radulescu, Vanya Gant
PURPOSE OF REVIEW: Pulmonary infections due to Gram-negative organisms are increasing worldwide and traditional assumptions that these are limited to hospital and ventilator-acquired pneumonia are rapidly falling away. Accordingly, empiric antibiotic guidelines have to follow suit with ever broader spectrum choices in order to remain 'safe', as the Global prevalence of extensively resistant Gram-negative organisms inexorably increases. Rapid, multiplex PCR-based detection of a wide variety of potential pathogens offers the opportunity to replace empiric antibiotic choices with targeted, evidence-based therapy in clinically actionable timeframes...
March 15, 2023: Current Opinion in Pulmonary Medicine
https://read.qxmd.com/read/36917216/approach-to-the-diagnosis-of-invasive-fungal-infections-of-the-respiratory-tract-in-the-immunocompromised-host
#4
JOURNAL ARTICLE
Hamish Houston, Andrew J Wilson, Neil Stone
PURPOSE OF REVIEW: The burden of invasive fungal infection is increasing worldwide, largely due to a growing population at-risk. Most serious human fungal pathogens enter the host via the respiratory tract. Early identification and treatment of invasive fungal respiratory infections (IFRIs) in the immunocompromised host saves lives. However, their accurate diagnosis is a difficult challenge for clinicians and mortality remains high. RECENT FINDINGS: This article reviews IFRIs, focussing on host susceptibility factors, clinical presentation, and mycological diagnosis...
March 15, 2023: Current Opinion in Pulmonary Medicine
https://read.qxmd.com/read/36917214/the-prevalence-of-childhood-asthma-interpreting-falling-rates-in-the-context-of-shifting-measurement-and-the-covid-19-pandemic
#5
JOURNAL ARTICLE
Sean M Frey, Regina K Rowe, Jill S Halterman
PURPOSE OF REVIEW: The estimated prevalence of childhood asthma in the United States, as measured by the National Health Information Survey (NHIS), has decreased by 30% since 2017. This review provides context for observed changes in asthma rates by describing recent shifts in NHIS data collection and analysis, and considers whether the COVID-19 pandemic might impact asthma prevalence in years to come. RECENT FINDINGS: The NHIS underwent a planned redesign in 2019 with updated sampling weights to better match the U...
March 15, 2023: Current Opinion in Pulmonary Medicine
https://read.qxmd.com/read/36876655/mass-gathering-events-and-transmission-of-respiratory-tract-infections-updates-pre-and-post-covid-19-lockdown
#6
JOURNAL ARTICLE
David S C Hui, Alimuddin Zumla
PURPOSE OF REVIEW: This article reviews the epidemiology and transmission of respiratory tract infections (RTIs) during mass gathering events (MGEs) before and during the COVID-19 pandemic. RECENT FINDINGS: RTIs of viral cause such as influenza, rhinovirus and coronaviruses (229E, HKU1, OC43) are common in MGEs. No cases of MERS-CoV have yet been identified in pilgrims during Hajj, despite the fact that MERS-CoV continues to circulate in the Middle East. Due to the COVID-19 pandemic, organizers of mass gathering religious and sporting events have implemented risk-based infection control measures and lockdowns that limited transmission of RTIs...
March 7, 2023: Current Opinion in Pulmonary Medicine
https://read.qxmd.com/read/36866737/airborne-transmission-of-respiratory-viruses-including-severe-acute-respiratory-syndrome-coronavirus-2
#7
JOURNAL ARTICLE
Julian W Tang, Linsey C Marr, Raymond Tellier, Stephanie J Dancer
PURPOSE OF REVIEW: The coronavirus disease 2019 pandemic has had a wide-ranging and profound impact on how we think about the transmission of respiratory viruses This review outlines the basis on which we should consider all respiratory viruses as aerosol-transmissible infections, in order to improve our control of these pathogens in both healthcare and community settings. RECENT FINDINGS: We present recent studies to support the aerosol transmission of severe acute respiratory syndrome coronavirus 2, and some older studies to demonstrate the aerosol transmissibility of other, more familiar seasonal respiratory viruses...
March 6, 2023: Current Opinion in Pulmonary Medicine
https://read.qxmd.com/read/36866734/eosinophilic-respiratory-disorders-and-the-impact-of-biologics
#8
JOURNAL ARTICLE
Joshua S Bernstein, Michael E Wechsler
PURPOSE OF REVIEW: Eosinophils are involved in combating parasitic, bacterial, viral infections as well as certain malignancies. However, they are also implicated in an array of upper and lower respiratory disease states. Through a deeper understanding of disease pathogenesis, targeted biologic therapies have revolutionized glucocorticoid sparing treatment of eosinophilic respiratory diseases. This review will focus on the impact of novel biologics on the management of asthma, eosinophilic granulomatosis with polyangiitis, allergic bronchopulmonary aspergillosis (ABPA), hypereosinophilic syndrome (HES) and chronic rhinosinusitis with nasal polyposis (CRSwNP)...
March 6, 2023: Current Opinion in Pulmonary Medicine
https://read.qxmd.com/read/36866728/advances-in-inhaled-antibiotics-for-management-of-respiratory-tract-infections
#9
JOURNAL ARTICLE
Vanessa Riveiro, Ana Casal, Romina Abelleira, Luis Vald├ęs
PURPOSE OF REVIEW: The incidence of bacterial respiratory tract infections is growing. In a context of increasing antibiotic resistance and lack of new classes of antibiotics, inhaled antibiotics emerge as a promising therapeutic strategy. Although they are generally used for cystic fibrosis, their use in other conditions is becoming more frequent, including no-cystic fibrosis bronchiectasis, pneumonia and mycobacterial infections. RECENT FINDINGS: Inhaled antibiotics exert beneficial microbiological effects in bronchiectasis and chronic bronchial infection...
March 6, 2023: Current Opinion in Pulmonary Medicine
https://read.qxmd.com/read/36866744/advances-in-development-of-new-tuberculosis-vaccines
#10
JOURNAL ARTICLE
Christopher da Costa, Philip Onyebujoh, Georges Thiry, Alimuddin Zumla
PURPOSE OF REVIEW: Tuberculosis (TB) remains a global public health emergency and caused 1.6 million deaths in 2021. The aim of this review is to provide recent updates on advances in TB vaccine development for prevention and adjunct therapy. RECENT FINDINGS: Targets use indications guiding late stage TB vaccine development have been established, namely: (i) Prevention of disease (PoD), (ii) Prevention of recurrent disease (PoR), (iii) Prevention of established infection in previously uninfected patients (PoI), and (iv) Adjunctive immunotherapy...
March 3, 2023: Current Opinion in Pulmonary Medicine
https://read.qxmd.com/read/36856551/nonpharmaceutical-interventions-for-managing-sars-cov-2
#11
JOURNAL ARTICLE
Caitriona Murphy, Jessica Y Wong, Benjamin J Cowling
PURPOSE OF REVIEW: Initial response strategies to the COVID-19 pandemic were heavily reliant on nonpharmaceutical interventions (NPIs), a set of measures implemented to slow or even stop the spread of infection. Here, we reviewed key measures used during the COVID-19 pandemic. RECENT FINDINGS: Some NPIs were successful in reducing the transmission of SARS-CoV-2. Personal protective measures such as face masks were widely used, and likely had some effect on transmission...
March 2, 2023: Current Opinion in Pulmonary Medicine
https://read.qxmd.com/read/36825398/effectiveness-and-safety-of-coronavirus-disease-2019-vaccines
#12
JOURNAL ARTICLE
Ting Shi, Chris Robertson, Aziz Sheikh
PURPOSE OF REVIEW: To review and summarise recent evidence on the effectiveness of coronavirus disease 2019 (COVID-19) vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and COVID-19 hospitalisation and death in adults as well as in specific population groups, namely pregnant women, and children and adolescents. We also sought to summarise evidence on vaccine safety in relation to cardiovascular and neurological complications. In order to do so, we drew primarily on evidence from two our own data platforms and supplement these with insights from related large population-based studies and systematic reviews...
February 27, 2023: Current Opinion in Pulmonary Medicine
https://read.qxmd.com/read/36644998/ageing-and-chronic-obstructive-pulmonary-disease-interrelationships
#13
JOURNAL ARTICLE
Krishna Kakkera, William T Atchley, Maneetha Kodali, Thaddeus Bartter
PURPOSE OF REVIEW: As life expectancy increases, the ageing population accrues an increasing burden of chronic conditions and functional compromise. Some conditions that lead to compromise are deemed part of 'natural ageing,' whereas others are considered to represent disease processes. Ageing ('a natural process') and chronic obstructive pulmonary disease ('a disease') share many common features, both pulmonary and systemic. At times, the pathways of injury are the same, and at times they are concurrent...
January 17, 2023: Current Opinion in Pulmonary Medicine
https://read.qxmd.com/read/36695765/silica-associated-lung-disease-in-developing-countries
#14
REVIEW
Sahajal Dhooria, Inderpaul Singh Sehgal, Ritesh Agarwal
PURPOSE OF REVIEW: There is a considerable burden of silica-associated lung diseases in the developing world. This review summarizes the epidemiology of these diseases, especially silicosis and silico-tuberculosis, mitigative efforts and treatment, especially in the context of developing countries. RECENT FINDINGS: In 2017, the highest incidence of silicosis was in China, India and Brazil among the developing countries. The prevalence of silicosis amongst exposed workers may vary from 4 to 55%; there is a risk of underestimation because of the 'healthy worker effect'...
March 1, 2023: Current Opinion in Pulmonary Medicine
https://read.qxmd.com/read/36695764/editorial-what-is-your-occupation-historical-snippets
#15
JOURNAL ARTICLE
Basil Varkey
No abstract text is available yet for this article.
March 1, 2023: Current Opinion in Pulmonary Medicine
https://read.qxmd.com/read/36695763/editorial-silicosis-asbestos-related-diseases-war-site-exposures-and-a-variety-of-topics-in-chronic-obstructive-pulmonary-disease
#16
JOURNAL ARTICLE
Manish Joshi, Basil Varkey
No abstract text is available yet for this article.
March 1, 2023: Current Opinion in Pulmonary Medicine
https://read.qxmd.com/read/36647566/interrelationships-between-tuberculosis-and-chronic-obstructive-pulmonary-disease
#17
REVIEW
Michael J Zavala, Greta L Becker, Robert J Blount
PURPOSE OF REVIEW: Our objective was to review the current literature regarding socioeconomic, environmental, clinical, and immunologic factors common to chronic obstructive pulmonary disease (COPD) and tuberculosis (TB). RECENT FINDINGS: Recent studies suggest that TB patients might be at increased risk for developing COPD. Conversely, additional prospective cohort studies have determined that COPD patients are at increased risk for active TB: a risk that appears to be partially mediated through inhaled corticosteroid use...
March 1, 2023: Current Opinion in Pulmonary Medicine
https://read.qxmd.com/read/36630203/asbestos-associated-pulmonary-disease
#18
REVIEW
Jose Diego Caceres, Anand N Venkata
PURPOSE OF REVIEW: Exposure to asbestos can cause both benign and malignant, pulmonary and pleural diseases. In the current era of low asbestos exposure, it is critical to be aware of complications from asbestos exposure; as they often arise after decades of exposure, asbestos-related pulmonary complications include asbestosis, pleural plaques, diffuse pleural thickening, benign asbestos-related pleural effusions and malignant pleural mesothelioma. RECENT FINDINGS: Multiple recent studies are featured in this review, including a study evaluating imaging characteristics of asbestos with other fibrotic lung diseases, a study that quantified pleural plaques on computed tomography imaging and its impact on pulmonary function, a study that examined the risk of lung cancer with pleural plaques among two large cohorts and a review of nonasbestos causes of malignant mesothelioma...
March 1, 2023: Current Opinion in Pulmonary Medicine
https://read.qxmd.com/read/36621855/recent-advances-predict-a-bright-future-for-nebulizers
#19
REVIEW
Michael Troy, Joseph Van Vleet, Donald Tashkin, Igor Barjaktarevic
PURPOSE OF REVIEW: With the improvement in device technology and delivery methods of inhaled medications, along with development of novel compounds and recognition of the importance of personalized approach in the management of chronic airway diseases, nebulizers have not only maintained their place in the treatment hierarchy of airway disease but have also proven a vital platform for the development of new classes of drugs. RECENT FINDINGS: This short review explores recent advances in nebulized drug delivery in chronic obstructive pulmonary disease and other chronic airway diseases, emphasizing the progress in nebulizer technology, physiologic advantages of nebulized drug delivery and the high versatility of currently available and developing nebulizer-delivered pharmacotherapies...
March 1, 2023: Current Opinion in Pulmonary Medicine
https://read.qxmd.com/read/36597757/military-deployment-related-respiratory-problems-an-update
#20
REVIEW
Eric Garshick, Paul D Blanc
PURPOSE OF REVIEW: Military personnel deployed to Southwest Asia and Afghanistan were potentially exposed to high levels of fine particulate matter and other pollutants from multiple sources, including dust storms, burn pit emissions from open-air waste burning, local ambient air pollution, and a range of military service-related activities that can generate airborne exposures. These exposures, individually or in combination, can have adverse respiratory health effects. We review exposures and potential health impacts, providing a framework for evaluation...
March 1, 2023: Current Opinion in Pulmonary Medicine
journal
journal
32189
1
2
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.