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Journal of Cardiac Failure

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https://read.qxmd.com/read/30776498/dancing-cats-heart-failure-and-circulating-troponin
#1
Jonathan G Howlett
No abstract text is available yet for this article.
February 16, 2019: Journal of Cardiac Failure
https://read.qxmd.com/read/30771477/improving-selection-of-mitraclip%C3%A2-candidates-in-advanced-chronic-heart-failure-look-right-to-predict-right
#2
LETTER
Simone Frea, Gabriele Crimi, Oliver Gaemperli, Stefano Pidello, Claudia Raineri, Fabrizio D'Ascenzo, Valeria Crescio, Paolo Boretto, Valeria Gritti, Francesca Giordana, Giulia Magrini, Sara Rettegno, Fabrizio Gazzoli, Alessandra Rabajoli, Antonio Montefusco, Maurizio Ferrario, Michele W La Torre, Maurizio D'Amico, Mauro Rinaldi, Frank Ruschitzka, Luigi Oltrona Visconti
No abstract text is available yet for this article.
February 13, 2019: Journal of Cardiac Failure
https://read.qxmd.com/read/30769037/eyeing-autonomic-dysregulation-in-heart-failure
#3
Khalil Murad, Mark Dunlap
No abstract text is available yet for this article.
February 12, 2019: Journal of Cardiac Failure
https://read.qxmd.com/read/30769036/-pro-renin-receptor-blockade-ameliorates-heart-failure-caused-by-chronic-kidney-disease
#4
Akihiro Yoshida, Hiromitsu Kanamori, Genki Naruse, Shingo Minatoguchi, Masamitsu Iwasa, Yoshihisa Yamada, Atsushi Mikami, Masanori Kawasaki, Kazuhiko Nishigaki, Shinya Minatoguchi
BACKGROUND: The (pro)renin receptor [(P)RR)] is involved in the activation of local renin-angiotensin system and subsequent development of cardiovascular disease. We investigated the therapeutic effect of a (P)RR blocker, handle region peptide (HRP), on chronic kidney disease (CKD)-associated heart failure. METHODS AND RESULTS: CKD was induced in C57BL/6J mice by 5/6 nephrectomy. Eight weeks later, cardiac dysfunction and cardiac dilatation with hypertension developed...
February 12, 2019: Journal of Cardiac Failure
https://read.qxmd.com/read/30769035/national-outcomes-in-hospitalized-patients-with-cancer-and-comorbid-heart-failure
#5
Mirela Tuzovic, Eric H Yang, René R Sevag Packard, Patricia A Ganz, Gregg C Fonarow, Boback Ziaeian
Heart failure (HF) and cancer are a significant cause of morbidity and mortality in the US. Due to overlapping risk factors, these two conditions often coexist. We sought to describe the national burden of HF for hospitalized patients with cancer. We identified adults admitted with a primary oncologic diagnosis in 2014 included in the National Inpatient Sample (NIS). Patient hospitalizations were divided based on presence or absence of comorbid HF. Primary outcomes included cost, length of stay (LOS), and inpatient mortality...
February 12, 2019: Journal of Cardiac Failure
https://read.qxmd.com/read/30763738/the-role-of-matrix-metalloproteinases-and-tissue-inhibitors-of-metalloproteinases-in-duchenne-muscular-dystrophy-cardiomyopathy
#6
Jonathan H Soslow, Meng Xu, James C Slaughter, Kimberly Crum, Joshua D Chew, W Bryan Burnette, Yan Ru Su, Kelsey Tomasek, David A Parra, Larry W Markham
BACKGROUND: Cardiomyopathy is the leading cause of death in Duchenne muscular dystrophy (DMD). Standard cardiac biomarkers are poor indicators of DMD cardiovascular disease. Matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) regulate collagen turnover. Given the cardiac fibrosis seen in DMD, we hypothesized that MMPs and TIMPs correlate with severity of DMD cardiomyopathy. METHODS AND RESULTS: Prospectively enrolled DMD subjects (n=42) underwent cardiac MRI for function and late gadolinium enhancement (LGE), including LGE severity from 0 (no LGE) to 4 (severe)...
February 11, 2019: Journal of Cardiac Failure
https://read.qxmd.com/read/30753936/reply-to-notarius
#7
LETTER
Andrew R Coggan, Linda R Peterson
No abstract text is available yet for this article.
February 9, 2019: Journal of Cardiac Failure
https://read.qxmd.com/read/30753935/diastolic-intra-left-ventricular-pressure-difference-during-exercise-strong-determinant-and-predictor-of-exercise-capacity-in-patients-with-heart-failure
#8
Shingo Tsujinaga, Hiroyuki Iwano, Miwa Sarashina, Taichi Hayashi, Michito Murayama, Ayako Ichikawa, Masahiro Nakabachi, Hisao Nishino, Shinobu Yokoyama, Arata Fukushima, Takashi Yokota, Kazunori Okada, Sanae Kaga, Pavlos P Vlachos, Toshihisa Anzai
BACKGROUND: Although the enhancement of early-diastolic intra-left ventricular pressure difference (IVPD) during exercise is considered to maintain exercise capacity, little is known about their relationship in heart failure (HF). METHODS AND RESULTS: Cardiopulmonary exercise testing and exercise-stress echocardiography were performed in 50 HF patients (left ventricular (LV) ejection fraction 39±15%). Echocardiographic images were obtained at rest, submaximal, and peak exercise...
February 9, 2019: Journal of Cardiac Failure
https://read.qxmd.com/read/30753934/driving-pulseless-a-driving-survey-of-patients-with-lvads-and-their-providers
#9
LETTER
Emily Seif
No abstract text is available yet for this article.
February 9, 2019: Journal of Cardiac Failure
https://read.qxmd.com/read/30753933/resting-oxygen-consumption-and-heart-failure-importance-of-measurement-for-determination-of-cardiac-output-using-the-fick-principle
#10
Gillian Grafton, Thomas Cascino, Daniel Perry, Carmel Ashur, Todd M Koelling
BACKGROUND: Resting oxygen consumption (VO2 ) is often estimated and frequently used to guide therapeutic decisions in symptomatic heart failure (HF) patients. The relationship between resting VO2 and symptomatic HF and the accuracy of estimations of VO2 in this population are unknown. METHODS AND RESULTS: We performed a cross-sectional study of HF patients (n=691) and healthy controls (n=77). VO2 was measured using a metabolic cart and estimated VO2 was calculated using the Dehmer, LaFarge, and Bergstra formulas and the thermodilution method...
February 9, 2019: Journal of Cardiac Failure
https://read.qxmd.com/read/30743044/empagliflozin-targeting-the-real-world-heart-failure-population
#11
LETTER
Bruno M L Rocha, Rita V Gomes, Gonçalo J L Cunha, Gonçalo Mendes, Rui Morais, L Campos, Inês Araújo, M Cândida Fonseca
No abstract text is available yet for this article.
February 8, 2019: Journal of Cardiac Failure
https://read.qxmd.com/read/30743043/accuracy-of-administrative-coding-to-identify-reduced-and-preserved-left-ventricular-ejection-fraction
#12
Paul A Heidenreich, Sundar Natarajan, Hossein Bahrami
BACKGROUND: Coding of systolic function in heart failure is important but the accuracy is uncertain. METHODS: We used data from chart review of VA heart failure hospitalizations between 2006 and 2013. Trained abstractors determined the documented diagnosis of heart failure and the left ventricular ejection fraction (LVEF). We compared this LVEF to the primary and secondary International Classification of Disease (ICD)-9 codes for heart failure for the same hospitalization...
February 8, 2019: Journal of Cardiac Failure
https://read.qxmd.com/read/30738153/why-would-the-effect-of-beet-root-juice-on-exercise-capacity-in-hfref-vary-with-etiology
#13
LETTER
Catherine Notarius
No abstract text is available yet for this article.
February 6, 2019: Journal of Cardiac Failure
https://read.qxmd.com/read/30738152/predictive-abilities-of-machine-learning-techniques-may-be-limited-by-dataset-characteristics-insights-from-the-unos-database
#14
P Elliott Miller, Sumeet Pawar, Benjamin Vaccaro, Megan McCullough, Pooja Rao, Rohit Ghosh, Prashant Warier, Nihar R Desai, Tariq Ahmad
BACKGROUND: Traditional statistical approaches to prediction of outcomes have drawbacks when applied to large clinical databases. It is hypothesized that machine learning methodologies might overcome these limitations by considering higher dimensional and nonlinear relationships among patient variables. METHODS: The Unified Network for Organ Sharing (UNOS) database was queried from 1987 to 2014 for adult patients undergoing cardiac transplantation. The data set was divided into 3 time-periods corresponding to major allocation adjustments and based on geographic regions...
February 6, 2019: Journal of Cardiac Failure
https://read.qxmd.com/read/30726714/doxycycline-and-ursodiol-for-attr-amyloidosis-not-ready-for-prime-time
#15
Ronald Witteles
No abstract text is available yet for this article.
February 3, 2019: Journal of Cardiac Failure
https://read.qxmd.com/read/30721735/relationship-of-liver-stiffness-with-congestion-in-patients-presenting-with-acute-decompensated-heart-failure
#16
Anzhela Soloveva, Zhanna Kobalava, Marat Fudim, Andrew P Ambrosy, Svetlana Villevalde, Munkhtsetseg Bayarsaikhan, Irina Garmash, Maksim Naumenko
OBJECTIVE: The significance of liver stiffness (LS) in the setting of cardiovascular congestion during the course of acute decompensated heart failure (ADHF) is under investigation. The aim of this study was to assess LS with transient elastography (TE) and its associations with volume overload by bioimpedance vector analysis (BIVA) in ADHF. METHODS AND RESULTS: TE (Fibroscan 502 Echosens, France) and BIVA (ABC-01 "Medass", Russia) were performed in the first 48 hours of admission and on the day of discharge in 149 ADHF patients without known primary chronic liver disease and acute hepatitis...
February 2, 2019: Journal of Cardiac Failure
https://read.qxmd.com/read/30721734/ischemic-cardiomyopathy-affects-the-thioredoxin-system-in-the-human-myocardium
#17
Stephan Neidhardt, Jens Garbade, Fabian Emrich, Kristin Klaeske, Michael A Borger, Sven Lehmann, Khalil Jawad, Maja-Theresa Dieterlen
BACKGROUND: Oxidative stress due to reactive oxygen species (ROS) production is one key factor in the development of heart failure (HF). The present study investigated the thioredoxin (Trx) system, which plays a major role in antioxidant defense, in patients suffering from ischemic (ICM) or dilative cardiomyopathy (DCM). METHODS: Myocardial tissue from ICM (n=13), DCM (n=13) as well as septal tissue of patients with aortic stenosis but without diagnosed hypertrophic cardiomyopathy and subaortic stenosis (control, n=12) was analyzed for Trx1, Trx-interacting protein (TXNIP) and E3-ligase ITCH expression...
February 2, 2019: Journal of Cardiac Failure
https://read.qxmd.com/read/30716400/influence-of-risk-on-reduction-of-readmission-and-death-by-disease-management-programs-in-heart-failure
#18
Quan L Huynh, Kristyn Whitmore, Kazuaki Negishi, Thomas H Marwick
OBJECTIVE: Disease management programs (DMP) may reduce short-term readmission or death after heart failure (HF) hospitalization. We sought to determine if targeting of DMP to the highest risk patients could improve efficiency. METHODS AND RESULTS: Patients (n=412) admitted with HF were randomized to usual care or an intensive DMP including optimizing intra-vascular volume status at discharge, increased self-care education, exercise guidance, closer home surveillance and increased intensity of HF nurse follow-up...
February 1, 2019: Journal of Cardiac Failure
https://read.qxmd.com/read/30716399/physiologic-adaptation-or-cirrhotic-cardiomyopathy-it-is-time-for-new-definitions
#19
Osama Altayar, Mauricio Lisker-Melman
No abstract text is available yet for this article.
February 1, 2019: Journal of Cardiac Failure
https://read.qxmd.com/read/30685400/elevated-heart-rate-following-heart-transplantation-is-associated-with-increased-graft-vasculopathy-and-mortality
#20
Max Liebo, Joshua Newman, Anjali Joshi, Brian D Lowes, Yael Peled-Potashnik, Haseeb Ilias Basha, Ronald Zolty, John Y Um, Edwin McGee, Alain Heroux, Eugenia Raichlin
BACKGROUND: The effect of elevated heart rate (HR) on outcomes following heart transplantation (HTx) has not been well established. The aim of this study was to assess predictors of elevated HR following HTx and its impact on outcomes. METHODS: We retrospectively evaluated 394 patients who underwent HTx at two academic medical centers between 2005-2016. Patients were divided into two groups based on HR 1 year after HTx: HR≥95 beats per minute (bpm; n=162 [41%]) and HR<95 bpm (n=232 [59%])...
January 24, 2019: Journal of Cardiac Failure
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