Bryce D Beutler, Kenneth Shinozuka, Burton J Tabaac, Alejandro Arenas, Kirsten Cherian, Viviana D Evans, Chelsey Fasano, Owen S Muir
BACKGROUND: Lysergic acid diethylamide (LSD) is a hallucinogenic agent. In the mid-20th century, it was used to augment psychoanalysis and to treat alcohol use disorder. However, LSD was banned in 1970 in part because of concerns that it could bring about or exacerbate mental illness. Its therapeutic potential remains incompletely understood. AREAS OF UNCERTAINTY: While uncontrolled recreational use of LSD can, in rare instances, lead to long-term psychosis, adverse events in clinical trials of LSD, such as anxiety, headache, and nausea, have almost always been mild and transient...
March 2024: American Journal of Therapeutics