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Prescrire International

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https://read.qxmd.com/read/30730676/new-products-and-new-indications-in-2016-a-system-that-favours-imitation-over-the-pursuit-of-real-progress
#1
(no author information available yet)
No abstract text is available yet for this article.
May 2017: Prescrire International
https://read.qxmd.com/read/30730675/pharmaceutical-research-and-development-a-new-system-is-needed
#2
(no author information available yet)
The system in operation since the late 20th cen- tury for stimulating pharmaceutical research and development (R&D) is increasingly showing seri- ous limitations. In particular, the new drugs it pro- duces are unaffordable and often offer only minor or even no benefits to patients. This system is under increasing criticism, not only from non-governmental organisations, but also from international institutions. A number of interesting proposals have been put forward to remedy the flaws in the current system or to estab- lish alternative systems...
May 2017: Prescrire International
https://read.qxmd.com/read/30730674/thrombophilia-testing-rarely-useful-after-a-venous-thromboembolic-event
#3
(no author information available yet)
Some people have coagulation abnormalities, collectively referred to as thrombophilia, which increase the risk of thrombosis. What are the most frequently detected thrombophilia? Does throm- bophilia testing after a venous thromboembolic event enable effective adjustment of the treatment strategy?To answer these questions, we reviewed the available evidence using the standard Prescrire methodology. The best known inherited thrombophilia includes the factorV Leiden mutation and the prothrombin G20210A mutation...
May 2017: Prescrire International
https://read.qxmd.com/read/30730673/rosacea-first-choice-treatments
#4
(no author information available yet)
No abstract text is available yet for this article.
May 2017: Prescrire International
https://read.qxmd.com/read/30730672/adverse-effects-of-short-course-corticosteroids-in-children
#5
(no author information available yet)
No abstract text is available yet for this article.
May 2017: Prescrire International
https://read.qxmd.com/read/30730671/natalizumab-retinal-necrosis
#6
(no author information available yet)
No abstract text is available yet for this article.
May 2017: Prescrire International
https://read.qxmd.com/read/30730670/drug-induced-excess-hair-growth
#7
(no author information available yet)
No abstract text is available yet for this article.
May 2017: Prescrire International
https://read.qxmd.com/read/30730669/insulin-degludec-liraglutide-xultophy%C3%A2-in-type-2-diabetes
#8
(no author information available yet)
No abstract text is available yet for this article.
May 2017: Prescrire International
https://read.qxmd.com/read/30730668/carfilzomib-kyprolis%C3%A2-in-multiple-myeloma
#9
(no author information available yet)
No abstract text is available yet for this article.
May 2017: Prescrire International
https://read.qxmd.com/read/30730667/pembrolizumab-keytruda%C3%A2-and-metastatic-or-inoperable-melanoma
#10
(no author information available yet)
No abstract text is available yet for this article.
May 2017: Prescrire International
https://read.qxmd.com/read/30730666/sufentanil-sublingual-tablets-zalviso%C3%A2-and-postoperative-analgesia
#11
(no author information available yet)
No abstract text is available yet for this article.
May 2017: Prescrire International
https://read.qxmd.com/read/30730665/towards-better-patient-care-drugs-to-avoid-in-2017
#12
(no author information available yet)
To help healthcare professionals and patients choose high-quality treatments that minimise the risk of adverse effects, in early 2017 we updated the list of drugs that Prescrire advises health pro- fessionals and patients to avoid. Prescire's assessments of the harm-benefit balance of new drugs and indications are based on a rigorous procedure that includes a systematic and reproducible literature search, identification of patient-relevant outcomes, prioritisation of the supporting data based on the strength of evidence, comparison with standard treatments, and an analysis of both known and potential adverse effects...
April 2017: Prescrire International
https://read.qxmd.com/read/30730664/digoxin
#13
(no author information available yet)
No abstract text is available yet for this article.
April 2017: Prescrire International
https://read.qxmd.com/read/30730663/fractures-related-to-bone-fragility-prevention-first-choice-treatments
#14
(no author information available yet)
No abstract text is available yet for this article.
April 2017: Prescrire International
https://read.qxmd.com/read/30730662/unborn-children-still-exposed-to-nsaids
#15
(no author information available yet)
No abstract text is available yet for this article.
April 2017: Prescrire International
https://read.qxmd.com/read/30730661/drug-induced-posterior-reversible-encephalopathy-syndrome
#16
(no author information available yet)
Posterior reversible encephalopathy syndrome (PRES) is a serious neurological disorder consisting of headache, visual disturbances, seizures, impaired consciousness and radiological evidence of poster- ior cerebral oedema. It is occasionally complicated by cerebral haemorrhage or ischaemia. The main known risk factors for PRES are hypertension, pre-eclampsia, eclampsia, acute kid- ney injury and numerous drugs. The main drugs implicated are antineoplastics, in particular VEGF inhibitors, immunosuppressants, and drugs that can increase blood pressure or fluid and sodium retention...
April 2017: Prescrire International
https://read.qxmd.com/read/30730660/ciclosporin-eye-drops-ikervis%C3%A2-and-dry-eye-syndrome
#17
(no author information available yet)
No abstract text is available yet for this article.
April 2017: Prescrire International
https://read.qxmd.com/read/30730659/adalimumab-humira%C3%A2-and-hidradenitis-suppurativa
#18
(no author information available yet)
No abstract text is available yet for this article.
April 2017: Prescrire International
https://read.qxmd.com/read/30730658/nivolumab-opdivo%C3%A2-and-metastatic-or-inoperable-lung-cancer
#19
(no author information available yet)
No abstract text is available yet for this article.
April 2017: Prescrire International
https://read.qxmd.com/read/30730657/inn-common-stem-onidine
#20
(no author information available yet)
No abstract text is available yet for this article.
April 2017: Prescrire International
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