Umut Varol, Ebru Cakır, Safiye Aktas, Zekiye Sultan Altun, Fatma Husniye Dilek, Osman Butun, Tarık Salman, Ayse Gulden Diniz Unlu, Ahmet Alacacioglu, Isil Somali
The aim of this study is to make a differential diagnosis and prognosis of the ampullary adenocarcinoma subtypes. We also investigated the role of prognostic markers PD-1 and PD-L1, and epidermal growth factor receptor (EGFR). Local or locally advanced stage ampullary adenocarcinoma patients who had undergone pancreaticoduodenectomy at the time of diagnosis were included. MUC1, MUC2, MUC5AC, CDX2, CK7, CK20, PD-1, and PDL-1 were analysed immunohistochemically, and EGFR was analysed by real-time polymerase chain reaction...
2023: Polish Journal of Pathology: Official Journal of the Polish Society of Pathologists