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Journals Saudi Journal of Kidney Diseas...

Saudi Journal of Kidney Diseases and Transplantation

https://read.qxmd.com/read/38995289/obesity-and-high-blood-pressure-in-chronic-kidney-disease
#1
LETTER
Renzo A Gonzales García, Rafael I Hernandez Patiño
No abstract text is available yet for this article.
December 1, 2023: Saudi Journal of Kidney Diseases and Transplantation
https://read.qxmd.com/read/38995288/successful-management-of-pulmonary-mucormycosis-presenting-as-round-pneumonia-by-lung-resection-in-a-kidney-transplant-recipient
#2
JOURNAL ARTICLE
Aniket Hase, Alpa Dalal, Amol Bhanushali, Kashmira Limaye, Supriya Dutta, Kanishka Davda, Tarang Kulkarni, Navin Jha, Niwrutti Hase
Pulmonary mucormycosis is rare in kidney transplant recipients and has a high mortality rate. We report a case of pulmonary mucormycosis presenting as round pneumonia 1 year and 1 month after the transplant. The diagnosis was confirmed by a percutaneous lung biopsy. A complete resection of the lung mass, followed by intravenous liposomal amphotericin B therapy, saved the life of the patient. In conclusion, early and prompt diagnosis followed by complete resection of the lesion in pulmonary mucormycosis is lifesaving...
December 1, 2023: Saudi Journal of Kidney Diseases and Transplantation
https://read.qxmd.com/read/38995287/a-case-of-postcoronavirus-disease-2019-antineutrophil-cytoplasmic-antibody-associated-vasculitis-successfully-treated-with-rituximab
#3
JOURNAL ARTICLE
Mahmoud M Mohamed, Atif Ibrahim, Zareen Razaq, Waleed Hassan
We report a case of a 69-year-old Caucasian male with a history of hypertension, Type 2 diabetes, and Stage IIIa chronic kidney disease (CKD), who presented to the emergency department with positional dizziness, generalized weakness, weight loss, and suppressed appetite. Two months earlier, the patient was diagnosed with coronavirus disease 2019 (COVID-19). The patient had non-oliguric acute kidney injury alongside preexisting CKD. The urinalysis showed hematuria and significant non-nephrotic proteinuria. His serological markers were positive for antineutrophil cytoplasmic antibodies with high titers...
December 1, 2023: Saudi Journal of Kidney Diseases and Transplantation
https://read.qxmd.com/read/38995286/adapting-clinical-practice-guidelines-for-chronic-kidney-disease-blood-pressure-management-and-kidney-replacement-therapy-in-adults-and-children-in-the-saudi-arabian-context-using-the-grading-of-recommendations-assessment-development-and-evaluation-adolopment
#4
JOURNAL ARTICLE
Khalid A Alhasan, Juan José Yepes-Nuñez, Sumayah Askandarani, Yasser S Amer, Muneera Al-Jelaify, Khalid I Almatham, Mohammed Al-Ghonaim, Sultan Al Dalbhi, Jameela A Kari, Ahmed Mitwalli, Ziad A Memish, Joanna Sara Valson, Ximena Alvira, Khushnam Bilimoria, Ruchi Chawla, Sheila Feit, Skye Bickett, Klara Brunnhuber
This practice guideline was developed by the chronic kidney disease (CKD) Task Force, which was composed of clinical and methodological experts. The Saudi Arabian Ministry of Health and its health holding company commissioned this guideline project to support the realization of Vision 2030's health-care transformation pillar. The synthesis of these guidelines was guided by the Grading of Recommendations Assessment, Development, and Evaluation (GRADE)- ADOLOPMENT methodology. The final guidelines addressed 12 clinical questions on the management of blood pressure in patients with CKD through a set of recommen-dations and performance measures...
December 1, 2023: Saudi Journal of Kidney Diseases and Transplantation
https://read.qxmd.com/read/38995285/evaluation-of-serum-visfatin-as-a-biomarker-of-lupus-nephritis-in-egyptian-patients-with-systemic-lupus-erythematosus
#5
JOURNAL ARTICLE
Amr Shaker, Ahmed Fayed, Mohamed Abdelkader Morad, Safa Labib, Riem M Elmessiery, Karem Mohamed Salem, Hend A ElSheimy, Hany Hammad, Ahmed Fathy
One of the most significant consequences of systemic lupus erythematosus (SLE) is lupus nephritis (LN). Visfatin, an adipokine that is significantly expressed in visceral fat and is a marker of endothelial dysfunction in chronic kidney disease, has multiple proinflammatory actions. We aimed to evaluate the state of serum visfatin in SLE patients and to detect its possible correlation with the disease's activity and effects on the kidney affection. Fifty patients with active LN, 50 patients with inactive lupus, and 50 healthy people had their serum visfatin levels tested...
December 1, 2023: Saudi Journal of Kidney Diseases and Transplantation
https://read.qxmd.com/read/38995284/the-prevalence-and-clinicopathological-spectrum-of-nondiabetic-renal-disease-in-patients-with-diabetes-in-a-tertiary-care-center
#6
JOURNAL ARTICLE
Bharathisezhian Anbuselvam, Senthilkumar Ramaiah Panneerselvam, Balasubramaniyan Thoppalan, Manoj Kumar
Diabetic nephropathy (DN) is a major complication of diabetes mellitus (DM), leading to end-stage renal disease. A wide spectrum of nondiabetic renal diseases (NDRDs) is reported in type 2 DM. We retrospectively reviewed the medical records of patients with type 2 DM who underwent a kidney biopsy from September 2019 to November 2021 at our center. Patients were grouped as having isolated DN, isolated NDRD, or mixed NDRD with underlying DN. According to the 379 renal biopsies performed during the study period, 57 patients had DM...
December 1, 2023: Saudi Journal of Kidney Diseases and Transplantation
https://read.qxmd.com/read/38995283/serum-interleukin-18-kidney-injury-molecule-1-and-the-renal-resistive-index-for-predicating-acute-kidney-injury-in-critically-ill-patients-with-sepsis
#7
JOURNAL ARTICLE
Amr Mohamed Shaker, Moataz F Mohamed, Karim K Thabet, Tarek Ramzy, Yasser M Abdelhamid
Interleukin-18 (IL-18) is a pro-inflammatory cytokine that rises approximately 24-48 h before a diagnosis of acute kidney injury (AKI). Kidney injury molecule-1 (KIM-1) is one of the most promising early biomarkers. It participates in the process of both kidney injury and healing, although the precise mechanism of the restoration of tubular integrity after injury still remains unclear. The renal resistive index (RRI) is used for evaluating changes in intrarenal perfusion occurring in renal parenchyma diseases...
December 1, 2023: Saudi Journal of Kidney Diseases and Transplantation
https://read.qxmd.com/read/38995282/acetyl-11-keto-%C3%AE-boswellic-acid-and-incensole-acetate-attenuate-lipopolysaccharide-induced-acute-kidney-injury-by-inhibiting-inflammation-and-oxidative-stress
#8
JOURNAL ARTICLE
Mohammad Rahim Sharifi, Zhara Hakimi, Mohammad Hosein Eshaghi Ghalibaf, Elham Fazeli, Farimah Behshti, Narges Marefati, Mahmoud Hosseini
Boswellia serrata has been used in traditional medicine to treat various inflammatory diseases. Acetyl-11-keto-β-boswellic acid (AKBA) and incensole acetate (IA) are two active ingredients of B. serrata that possess anti-inflammatory and antioxidant activities. The present study aimed to investigate the protective effects of AKBA and IA against lipopolysaccharide (LPS)- induced acute kidney injury (AKI) in rats. Wistar rats were intraperitoneally pretreated with AKBA or IA for 2 weeks. After 30 min, an LPS injection was applied to induce AKI...
December 1, 2023: Saudi Journal of Kidney Diseases and Transplantation
https://read.qxmd.com/read/38995281/diagnostic-values-of-immature-granulocytes-detected-by-the-sysmex-xn-9000-hematology-analyzer-in-children-with-urinary-tract-infections
#9
JOURNAL ARTICLE
Nuran Cetin, Evin Kocaturk, Asli Kavaz Tufan, Zeynep Kusku Kiraz, Ozkan Alatas
Immature granulocytes (IGs) are used as markers of infection and systemic inflammation. We aimed to investigate the diagnostic value of IGs in children with urinary tract infections (UTIs). Children with their first UTIs were included in this observational study. Blood samples were obtained before antibiotic therapy. The blood analysis was repeated 2 weeks after the treatment ended. In total, 194 children (95 with febrile UTI, 58 with cystitis, and 41 controls) were included. The percentage of IGs (IG%) and IG count (IGC) measured at the time of admission were higher in the patients with febrile UTI than in the patients with cystitis and the controls (P = 0...
December 1, 2023: Saudi Journal of Kidney Diseases and Transplantation
https://read.qxmd.com/read/38995280/quality-of-life-among-hemodialysis-patients-role-of-the-dialysis-shift
#10
JOURNAL ARTICLE
Safa Nowrooz, Turki Alanazi, Abdulmohsen Al-Ghamdi, Abdulaziz Alzahrani, Abdulrahman Alshammari, Neda AlYaqoot, Mana Almutraid, Ahmed Jaradat, Amgad El-Agroudy
This study examined the effects of the time of hemodialysis (HD) on patients' quality of life (QOL). This study included 175 HD patients (116 males, 59 females), aged 18-80 years (mean = 58.1 ± 11.3 years). Shift 1 was 7:00-11:00 AM, Shift 2 was 12:00-4:00 PM, Shift 3 was 5:00-9:00 PM, and Shift 4 was 10:00-2:00 AM (38, 38, 43, and 56 patients, respectively). Those on Shift 4 had a higher mean age compared with the other shifts, with a higher number of widowed people (8.6%). The proportions of males and females showed no significant differences among the shifts...
December 1, 2023: Saudi Journal of Kidney Diseases and Transplantation
https://read.qxmd.com/read/38995279/correlation-of-urinary-neutrophil-gelatinase-with-the-histopathological-extent-of-kidney-damage-in-patients-with-diabetic-nephropathy
#11
JOURNAL ARTICLE
Priya Garg, Manjunath Shetty, Vani Krishnamurthy
Diabetic nephropathy (DN), a leading cause of chronic kidney disease, is known to develop in around 40% of patients with diabetes. NGAL, a biomarker expressed by the tubular epithelium, has been evaluated in both acute and chronic kidney injury. However, kidney damage revealed by the histology of renal tissue core biopsies has not been quantified by morphometry and its correlation with urinary NGAL (uNGAL) has not been studied. Our objective was to compare levels of uNGAL with the extent of kidney damage in the histopathological results of morphometry in patients with DN...
December 1, 2023: Saudi Journal of Kidney Diseases and Transplantation
https://read.qxmd.com/read/38995278/a-prospective-observational-study-of-renal-involvement-in-hematological-malignancies
#12
JOURNAL ARTICLE
Mahesh Eshwarappa, Rajashekar, Gireesh Mathihally Siddaiah, Konana Chennabasappa Gurudev, Karteek Udupa, Mohammad Yusuff
Patients with hematological malignancies (HMs) are at high risk of infections and comorbidities that substantially increase the occurrence of renal failure. Thus, the management of renal dysfunction in patients with HMs is crucial. The current study aimed to determine the incidence of renal involvement in patients with HMs and analyze their clinical profile in the context of renal disorders. A prospective observational study was conducted on 200 patients suffering from various HMs. Renal involvement was determined through blood and urine analyses...
December 1, 2023: Saudi Journal of Kidney Diseases and Transplantation
https://read.qxmd.com/read/38995277/microalbuminuria-and-its-correlation-with-the-severity-of-coronary-artery-disease-a-cross-sectional-study-in-a-rural-area-of-central-india
#13
JOURNAL ARTICLE
Sanyukta Hepat, Sunil Kumar, Sourya Acharya, Anil Wanjari, Shilpa Bawankule, Sachin Agrawal, Anuj Varma, Abhijit Wadekar, Nipun Bawiskar, Sameera Dronamraju
Microalbuminuria is a well-established, strong, and independent risk factor of cardiovascular disease. Patients with microalbuminuria are also said to have a higher atherosclerotic load in the form of multivessel coronary artery disease (CAD) than those who do not. In this study, we tried to correlate microalbuminuria with the severity of CAD. In this cross-sectional study, 100 patients with CAD diagnosed on the basis of coronary angiography were enrolled from August 2019 to August 2021. Triple-vessel CAD was observed in 79...
December 1, 2023: Saudi Journal of Kidney Diseases and Transplantation
https://read.qxmd.com/read/38995276/antihypertensive-and-antioxidant-effects-of-an-aqueous-extract-of-asafetida-in-renovascular-hypertensive-rats
#14
JOURNAL ARTICLE
Farzaneh Kazemi, Reza Mohebbati, Mohammad Naser Shafei
Recently, the effect of an aqueous extract of asafetida on acute angiotensin II hypertensive rats was evaluated. The present study evaluated the antihypertensive and antioxidant effects of asafetida on a rat model of renovascular hypertension (RVH) using four groups. RVH was induced by clipping the renal artery; the sham group underwent surgery but without clipping. The RVH rats received losartan (Los, an AT1 receptor antagonist) or asafetida by gavage for 4 weeks. On the 28th day, the femoral artery was cannulated, and the systolic blood pressure (SBP), mean arterial pressure (MAP), and heart rate (HR) were recorded...
December 1, 2023: Saudi Journal of Kidney Diseases and Transplantation
https://read.qxmd.com/read/38995275/integration-of-urinary-neutrophil-gelatinase-associated-lipocalin-with-the-renal-angina-index-to-predict-subsequent-severe-acute-kidney-injury-in-critically-ill-children-a-diagnostic-accuracy-study
#15
JOURNAL ARTICLE
Ngilyang Sunya, Shalu Gupta, Abhijeet Saha
The primary objective of this study was to determine the performance of the renal angina index (RAI) in predicting subsequent severe acute kidney injury (AKI) on day 3 of admission and whether integrating urinary neutrophil gelatinase-associated lipocalin (NGAL) with RAI would lead to improved prediction of AKI. This was a prospective observational study conducted in the pediatric intensive care unit (PICU) of a tertiary care hospital involving 170 children meeting the inclusion criteria. The RAI was assessed within 24 h of admission to the PICU...
December 1, 2023: Saudi Journal of Kidney Diseases and Transplantation
https://read.qxmd.com/read/38995274/assessing-health-related-quality-of-life-in-children-with-chronic-kidney-disease-in-indonesia-a-single-tertiary-hospital-study
#16
JOURNAL ARTICLE
Retno Palupi-Baroto, Braghmandita W Indraswari, Asal Wahyuni Erlin Mulyadi, Siti N Rusdhy, Kharisma N Prabowo, Kristia Hermawan
Health-related quality of life (HRQOL) is an important patient-reported outcome. However, HRQOL research in pediatric patients with chronic kidney disease (CKD) in developing countries is limited. This cross-sectional study involved children with CKD who attended Dr. Sardjito General Hospital between January 2017 and September 2018. In total, 82 child-parent pairs were enrolled. Total HRQOL scores were significantly lower in children with Stages 3a-5 CKD than in children with Stages 1-2 CKD in the child (69...
December 1, 2023: Saudi Journal of Kidney Diseases and Transplantation
https://read.qxmd.com/read/38995273/factors-associated-with-nonadherence-to-dietary-prescriptions-among-hemodialysis-patients-makkah-saudi-arabia
#17
JOURNAL ARTICLE
Ghanim Hamid Al-Khattabi
The nonadherence of hemodialysis (HD) patients correlates with morbidity and mortality. Despite severe consequences, noncompliance with their medical regimen is the norm for HD patients rather than the exception. Factors associated with nonadherence to dietary restrictions among HD patients have been explored in many studies; however, most were in Western countries and there is a remarkable paucity of studies in Saudi Arabia. HD patients have several features that put them at an increased risk of nonadherence to dietary restrictions, including prolonged, intensive treatment, and their medical regimens are easily determined with objective measures...
December 1, 2023: Saudi Journal of Kidney Diseases and Transplantation
https://read.qxmd.com/read/38995272/adherence-of-hemodialysis-patients-to-fluid-diet-medications-and-hemodialysis-sessions-makkah-saudi-arabia
#18
MULTICENTER STUDY
Ghanim Hamid Al-Khattabi
The adherence of hemodialysis (HD) patients to medical instructions is considered crucial for a longer life expectancy and better quality of life. Despite its importance, there is a remarkable paucity in research dealing with the adherence of patients under HD in Saudi Arabia. The objective of this study was to identify the prevalence of adherence to fluid, diet, medications, and HD sessions among HD patients in Makkah. This was a cross-sectional study in which 361 HD patients were randomly selected from HD centers in three governmental hospitals in Makkah...
December 1, 2023: Saudi Journal of Kidney Diseases and Transplantation
https://read.qxmd.com/read/38995271/ambulatory-blood-pressure-monitoring-versus-office-blood-pressure-monitoring-to-identify-the-true-hypertension-status-of-living-kidney-donors
#19
COMPARATIVE STUDY
Jawad Iqbal Rather, Khalid P Sofi, Muzamil Ahmad Wani, Muzafar Maqsood Wani, Rabiya Rasheed, Mohammad Ashraf Bhat, Imtiyaz Ahmad Wani
Ambulatory blood pressure monitoring (ABPM) is a reliable modality and is preferred over office blood pressure monitoring (OBPM) for detecting hypertension. However, despite its advantages, the utilization of 24-h ABPM in evaluating living kidney donors has not been universally adopted by transplant centers, partly because of the lack of data about the utility of ABPM. This study aimed to identify patients with masked and white-coat hypertension, thereby ensuring appropriate identification of their true hypertension status and assessments of the risk to donors...
December 1, 2023: Saudi Journal of Kidney Diseases and Transplantation
https://read.qxmd.com/read/38995270/comparison-of-renal-function-before-and-after-autologous-stem-cell-transplantation-in-egyptian-patients-with-multiple-myeloma-and-renal-insufficiency-a-retrospective-study
#20
COMPARATIVE STUDY
Mohamed Abdelkader Morad, Omar Fahmy, Mohamed A Marie, Eman Samir, Reham Emad Eldin Abdullah
Renal failure is a common feature of multiple myeloma (MM) that occurs in 20%-40% of newly diagnosed patients with MM and is the result of monoclonal immunoglobulin light chains. Many studies have examined the effect of autologous stem cell transplantation (ASCT) in MM patients with renal impairment and the safety of performing the transplantation in patients with renal failure. This study aimed to compare renal function before and after ASCT in Egyptian MM patients with renal insufficiency to evaluate the effect of ASCT on renal recovery...
December 1, 2023: Saudi Journal of Kidney Diseases and Transplantation
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