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Journals Acta Dermatovenerologica Croat...

Acta Dermatovenerologica Croatica : ADC

https://read.qxmd.com/read/38006371/frank-s-sign-a-link-between-dermatovenerology-cardiac-pathology-and-neurology
#41
JOURNAL ARTICLE
Denis Čerimagić
Dear Editor, Although some of my colleagues may find this surprising, as a neurologist, I have noticed many connections between dermatology and neurology. Neurological and dermatological signs and symptoms are common in many clinical entities, especially in the so-called phakomatoses or neurocutaneous syndromes (Von Recklinghausen's disease type 1 and 2, Bourneville-Pringle syndrome, Sturge-Weber syndrome, Von Hippel-Lindau syndrome, Louis-Bar syndrome) (1). The terms "neurodermatitis" and "neurodermatology" also confirm the above...
November 2023: Acta Dermatovenerologica Croatica: ADC
https://read.qxmd.com/read/38006370/folliculotropism-in-actinic-keratoses-in-patients-not-responding-to-treatments-a-pilot-study
#42
JOURNAL ARTICLE
Emi Dika, Emi Dika, Martina Lambertini, Emi Dika, Martina Lambertini, Giulia Veronesi, Cosimo Misciali, Massimo Milani, Aleksandra Bergant-Suhodolcan, Bor Hrvatin Stancic, Carlotta Baraldi
Dear Editor, Actinic keratoses (AK) have a high prevalence in the general population, with greater rates in Caucasian patients after the fourth and fifth decades of life (37.5-60.0%) (1,2). Standard histopathologic reporting of AKs does not provide information on the presence of atypical keratinocytes extending to the hair follicle, also defined as folliculotropism (FLC). Commonly, atypical cells in AKs do not present FLC, but this feature can be observed in bowenoid AKs with full-thickness epidermal atypia (3,4)...
November 2023: Acta Dermatovenerologica Croatica: ADC
https://read.qxmd.com/read/38006369/aulus-cornelius-celsus-de-medicina-and-his-contributions-to-knowledge-on-skin-diseases
#43
JOURNAL ARTICLE
Franjo Gruber
The book De Medicina by Aulus Cornelius Celsus was the first complete treatise about medicine written in Latin. We know little about his life. The monography consists of eight books describing all that was known within the whole sphere of medicine and surgery in the first century AD. In the introduction (proemium), he also described the history of medicine until his time and also delineated the treatment of diseases that may be dietetic, medication-based or surgical. The treatise describes approximately forty skin diseases in a concise and clear style...
November 2023: Acta Dermatovenerologica Croatica: ADC
https://read.qxmd.com/read/38006368/prognostic-value-of-lactate-dehydrogenase-in-patients-with-melanoma-treated-with-pembrolizumab
#44
JOURNAL ARTICLE
Aleksandar Popović, Ivan Petković, Aleksandra Dimitrijevic, Andrija Jović
INTRODUCTION: Elevated LDH levels have been extensively reported as a biomarker of poorer outcome in patients with melanoma during the chemotherapeutic era. The role of LDH level as a prognostic factor for treatment outcomes in patients with metastatic melanoma treated with immunooncological therapy has also been reported but requires further analysis. OBJECTIVES: In this study, we aimed to evaluate the prognostic value of lactate dehydrogenase (LDH) among patients with metastatic and unresectable melanoma treated with pembrolizumab in terms of progression-free survival (PFS)...
November 2023: Acta Dermatovenerologica Croatica: ADC
https://read.qxmd.com/read/38006367/alterations-in-inflammation-markers-due-to-disease-activation-in-autoimmune-bullous-diseases
#45
JOURNAL ARTICLE
Gokhan Sahin, Esra Pancar Yuksel, Fatma Aydin
BACKGROUND: In the pathogenesis of autoimmune bullous diseases, there is an underlying autoinflammation against epidermal/subepidermal structures caused by many inflammatory cells. Aim / Objectives: In this study, we aimed to determine the alterations in inflammatory markers regarding disease activity in autoimmune bullous diseases and to discuss their contribution to the pathogenesis. METHODS: A total of 191 patients with pemphigus vulgaris (PV) and 46 patients with bullous pemphigoid (BP) who were admitted to the outpatient clinic at the Department of Dermatology were included...
November 2023: Acta Dermatovenerologica Croatica: ADC
https://read.qxmd.com/read/38006366/the-role-of-t-follicular-helper-cells-in-clinical-remission-and-relapse-in-patients-with-pemphigus-treated-with-rituximab
#46
JOURNAL ARTICLE
Ayşe Akman Karakaş, Erkan Ergün, Nurten Sayın Ekinci, Aslı Toylu, Soner Uzun, Erkan Alpsoy
BACKGROUND: Pemphigus is a rare chronic autoimmune disease. Recent studies have found that T follicular helper (Tfh) cells may play a role in autoimmune diseases. In this study, Tfh cells frequency, BCL6 gene expression, IL-21, and IL-6 cytokines levels were examined, with the aim of understanding the effect of RTX on these cells in the onset of clinical remission or relapse in patients with pemphigus. METHODS: 20 patients with pemphigus vulgaris and 20 healthy controls without any autoimmune diseases that were admitted to the Dermatology and Venereology Clinic of the Akdeniz University Hospital were included...
November 2023: Acta Dermatovenerologica Croatica: ADC
https://read.qxmd.com/read/38006365/the-impact-of-blue-light-irradiation-on-keratinocytes-in-vitro
#47
JOURNAL ARTICLE
Markus Denzinger, Andreas K Nüssler, Fabian Medved, Sabrina Krauß, Adrien Daigeler, Manuel Held, Claudius Illg
BACKGROUND: This study examined the effects of irradiation with blue light on HaCaT keratinocytes. As irradiation with blue light is known to be antimicrobial, it offers a promising alternative therapy for contaminated wounds. There is evidence that red light promotes wound healing, but the potential benefits of irradiation with blue light have not yet been adequately investigated. METHODS: The rate of wound closure in sterile and contaminated cells was measured using an in vitro scratch assay wound-healing model...
November 2023: Acta Dermatovenerologica Croatica: ADC
https://read.qxmd.com/read/38006364/insulin-growth-factor-1-status-in-hidradenitis-suppurativa-a-french-institutional-pilot-study
#48
JOURNAL ARTICLE
Perrine Rousseau, Alexandra Poinas, Damien Masson, Kalyane Bach-Ngohou, Michel Nguyen, Marie Le Moigne, Barbara Bregeon, Florence Vrignaud, Amir Khammari, Brigitte Dréno
BACKGROUND: Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease of the follicles in the apocrine glands and is associated with a deficiency in the innate immunity of the skin. It is characterized by the occurrence of nodules, abscesses, fistulas, scars. OBJECTIVE: Although a relationship has already been demonstrated between HS and innate immunity, IGF-1 status in patients with HS is still unknown. The objective of this pilot study was to determine IGF-1 status in patients with HS as well as its potential relationship with the clinical profile of the disease...
November 2023: Acta Dermatovenerologica Croatica: ADC
https://read.qxmd.com/read/37843094/the-leser-tr%C3%A3-lat-sign-in-a-patient-with-gastric-adenocarcinoma
#49
JOURNAL ARTICLE
Antonela Geber, Ayla Hadžavdić, Suzana Ljubojević Hadžavdić
Dear Editor, The Leser-Trélat sign is a rare paraneoplastic cutaneous marker of internal malignancy characterized by sudden eruption of multiple seborrheic keratoses (SK). It is mostly associated with gastrointestinal adenocarcinomas (gastric, colon, rectal), and less frequently with breast cancer and lymphoproliferative disorders/lymphoma (1). It can be also associated with lung, kidney, liver, and pancreas malignancy (1). Pruritus occurs in half of the patients. Lesions rarely require any treatment, as they mostly tend to resolve once management of the underlying malignancy has started (2)...
August 2023: Acta Dermatovenerologica Croatica: ADC
https://read.qxmd.com/read/37843093/brodalumab-seems-to-recover-its-therapeutic-efficacy-after-a-relatively-short-washout-period-with-anti-tnf-agents-a-successful-pattern-for-double-switch-therapy
#50
MULTICENTER STUDY
Eleftheria Tampouratzi, Konstantinos Sfaelos, Kyriakos Talaiporou, Τheodora Douvali, John Katsantonis
Psoriasis is a lifelong disease with a chronic relapsing course, and treatment agent switching is a common and accepted practice in cases of primary or secondary inadequate response. Patients with prior biologic treatment failure or loss of response are a subset of individuals who most likely have more severe disease with a greater impact on quality of life. Additionally, switching between multiple biologics is associated with clinical consequences (e.g. development of anti-drug antibodies), which may limit efficacy of subsequent biologic therapies (1,2)...
August 2023: Acta Dermatovenerologica Croatica: ADC
https://read.qxmd.com/read/37843092/morphea-after-silicone-implants
#51
JOURNAL ARTICLE
Uwe Wollina, Jacqueline Schönlebe
Dear Editor, Silicone is a hydrophobic polymer containing silicon. Silicon is an essential compound of soft tissue proteoglycans. Reports about morphea and other autoimmune connective tissue disorders in association with silicone implants have stimulated the discussion of a possible link between the two, such as immunological cross-reactivity of silicone and connective tissue components (1). A number of case reports suggested a possible link to adjuvant autoimmune syndrome (2), morphea of the breast (3-5), and systemic scleroderma (6-8), among others...
August 2023: Acta Dermatovenerologica Croatica: ADC
https://read.qxmd.com/read/37843091/pemphigus-vegetans-of-hallopeau-a-case-report
#52
JOURNAL ARTICLE
Jelena Maljić, Jaka Radoš, Davorin Lončarić, Ines Lakoš Jukić
Dear Editor, Pemphigus vegetans (PV) of Hallopeau is a rare and indolent variant of pemphigus clinically characterized by vegetating lesions preceded by pustules mainly in flexural areas (1,2). This helps us to differentiate it from PV of Neumann, which is a more extensive and refractory disease, more alike to a pemphigus vulgaris outbreak with blisters which turn into vegetating plaques (3). We report the clinical presentation, course, and therapeutic response in a patient diagnosed with PV of Hallopeau from its early stage during a 3-year follow up...
August 2023: Acta Dermatovenerologica Croatica: ADC
https://read.qxmd.com/read/37843090/melanoma-developing-from-an-intradermal-nevus-report-on-two-patients
#53
JOURNAL ARTICLE
Daniela Ledić Drvar, Jaka Radoš, Ivana Manola, Ana Mataić, Snježana Dotlić, Božo Krušlin
Dear Editor, Approximately 25-33% of cutaneous melanomas arise from nevi (1). Shitara et al. suggested that junctional and compound nevi are more likely give rise to melanoma than intradermal nevi, but this has not been definitively confirmed (2). Based on these results and our own clinical observation on rare malignant transformation in intradermal nevi, we present two patients with melanoma developing from an intradermal nevus. The first patient, a 63-year-old woman, presented with a suspicious lesion in 2017 on the upper back in the form of a dark brown macula juxtapositioned next to the dermal nevus (Figure 1, a)...
August 2023: Acta Dermatovenerologica Croatica: ADC
https://read.qxmd.com/read/37843089/giant-primary-apocrine-carcinoma-of-the-frontal-region-clinical-presentation-histopathological-features-and-surgical-treatment
#54
Dragana Petrović Popović, Marijan Novaković, Milan Stojičić, Dimitrije Brašanac, Mirjana Petrović-Elbaz
Primary cutaneous apocrine carcinoma (PCAC), a subtype of sweat gland carcinoma, is an extremely rare malignant neoplasm. Distinguishing an apocrine carcinoma from a breast carcinoma metastasis is difficult even for a pathologist. Most arise in regions of high apocrine gland density like the axilla, and rarely on the scalp and eyelid, but they can occur elsewhere on the skin. Primary cutaneous apocrine carcinoma of the scalp is a rare malignancy most often reported in the literature as case reports or small case series...
August 2023: Acta Dermatovenerologica Croatica: ADC
https://read.qxmd.com/read/37843088/ashy-dermatosis-in-a-two-year-old-child-a-case-report-and-mini-review
#55
Shumpei Kamano, Eri Hotta, Sachiko Goto, Mizuho Inagawa
Ashy dermatosis, or erythema dyschromicum perstans, is characterized by acquired grey patches distributed on the face, neck, trunk, and extremities with an unknown pathophysiology. Herein, we report a case of ashy dermatosis in a two-year-old child, possibly caused by an infection, with eventual improvement within two years, absent any treatment. To our knowledge, this is the second report of ashy dermatosis in a patient under the age of three years, and the first under the age of two years that was followed-up in the English-language literature from 2000 to 2021...
August 2023: Acta Dermatovenerologica Croatica: ADC
https://read.qxmd.com/read/37843087/segmental-erythema-multiforme-an-unusual-drug-reaction-to-anastrozole
#56
Sanja Poduje, Luka Vujević, Nika Filipović, Majda Vučić, Marija Buljan
Erythema multiforme (EM) is an immune-mediated, mucocutaneous hypersensitivity syndrome that can occur as a result of various medications, including a wide range of antineoplastic and hormonal drugs. Anastrozole, a nonselective aromatase inhibitor used in breast cancer management has been associated with different cutaneous side effects, of which EM is rarely seen and usually in a minor or major form with typical target lesions. This is a short report of a patient who developed a rare cutaneous side effect after the use of aromatase inhibitor anastrozole - segmental erythema multiforme in cancer-affected area...
August 2023: Acta Dermatovenerologica Croatica: ADC
https://read.qxmd.com/read/37843086/hand-foot-and-mouth-disease-in-children-clinical-characteristics-of-an-outbreak-in-novi-sad-serbia
#57
JOURNAL ARTICLE
Sonja Prćić, Aleksandra Matić, Milan Matić, Anica Radulović, Zorica Gajinov
Hand, foot, and mouth disease (HFMD) is a relatively common mild viral infection that usually affects young children, mainly occurring during the late spring, early summer, and fall months. It is most commonly caused by members of the human enterovirus (HEV) genus. Recently, HFMD has received renewed attention because of evidence that this disease could have clinical, epidemiological, and etiological characteristics different from those initially associated with it. HFMD may be associated with neurologic or cardiopulmonary complications and can, rarely, lead to death...
August 2023: Acta Dermatovenerologica Croatica: ADC
https://read.qxmd.com/read/37843085/dermatitis-artefacta-a-practical-guide-for-diagnosis-and-management
#58
JOURNAL ARTICLE
Julio Torales, Karina Malvido, María Alejandra Vázquez, Iván Barrios, José Almirón-Santacruz, Rodrigo Navarro, Marcelo O'higgins, Gabriel Casas, João Mauricio Castaldelli-Maia, Antonio Ventriglio, Israel González-Urbieta
Dermatitis artefacta (DA) is a psycho-dermatologic condition based on patients' behavioral patterns, characterized by an intentional production of cutaneous lesions on their own skin. The clinical presentation can be highly variable. Patients with DA seldom seek psychological support or psychiatric consultation. More often, they seek help from their primary care physician or dermatologist. This review article aims to provide a practical guide for the diagnosis and management of AD and affected patients. A broad literature search was performed using the PubMed and Google Scholar electronic online databases, using key words "dermatitis artefacta", "diagnosis", "management", and "psychodermatology"...
August 2023: Acta Dermatovenerologica Croatica: ADC
https://read.qxmd.com/read/37843084/impact-of-the-covid-19-pandemic-on-adult-patients-with-atopic-dermatitis
#59
JOURNAL ARTICLE
Weronika Zysk, Magdalena Trzeciak
Atopic dermatitis (AD) is a chronic, inflammatory, itchy dermatosis with periods of remissions and exacerbations. Social isolation and lockdown measures may cause increased stress which in turn may affect the skin condition of patients with AD. We aimed to investigate the impact of the COVID-19 pandemic on the course of AD and the mental health of adult patients with AD. The study was based on an anonymous online questionnaire. A total of 91 adult patients with AD participated in this survey. The study population consisted of 77 (84...
August 2023: Acta Dermatovenerologica Croatica: ADC
https://read.qxmd.com/read/37843083/the-impact-of-atopic-dermatitis-and-corticophobia-on-the-quality-of-family-life
#60
JOURNAL ARTICLE
Oksana Kotarski, Marija Pečnjak, Mario Blekić, Ivana Bukvić, Blaženka Kljaić Bukvić
The aim of the study was to investigate the impact of atopic dermatitis (AD) in children and corticophobia on the quality of family life. Children with AD and their parents were included in a cross-sectional study. The severity of AD was self-assessed using the Patient Oriented-Scoring of Atopic Dermatitis (PO-SCORAD) index, and the severity of corticophobia using the Topical Corticosteroid Phobia (TOPICOP) score, and the general impact of AD on family quality of life using the Family Dermatology Life Quality Index (FDLQI)...
August 2023: Acta Dermatovenerologica Croatica: ADC
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