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Journals Acta Dermatovenerologica Croat...

Acta Dermatovenerologica Croatica : ADC

https://read.qxmd.com/read/38439723/aquatic-aquagenic-dermatoses-the-thin-line-between-pool-palms-and-aquagenic-syringeal-acrokeratoderma
#21
Deniz Demircioğlu, Emel Öztürk Durmaz
Pool palms and pool toes are friction or pressure-induced aquatic dermatoses resulting from extensive and repetitive rubbing of fingers, palms, soles, and toes against the rough anti-slippery surfaces or edges of pools. Aquagenic syringeal acrokeratoderma is a sporadic, episodic, and acquired disorder of palmar skin linked to water exposure. Herein we describe a case of aquatic/aquagenic dermatosis that presented clinical and diagnostic difficulties. Differentiating between pool palms and aquagenic syringeal acrokeratoderma is a challenge, and we believe that both disorders lie on a spectrum of watersport dermatoses...
December 2023: Acta Dermatovenerologica Croatica: ADC
https://read.qxmd.com/read/38439722/he-influence-of-academician-franjo-kogoj-on-global-dermatology
#22
REVIEW
Tomislav Duvančić, Mirna Šitum
Academician Franjo Kogoj graduated medicine in 1920 in Prague, where he then pursued training in dermatovenerology. During later years, he also visited other dermatology clinics in Europe, where he collaborated with renowned dermatologists of the time, such as in Breslau (present day Wroclaw in Poland) with Josef Jadassohn and in Strasbourg with Lucien-Marie Pautrier. He was also active in the famous Saint-Louis hospital in Paris. Academician Kogoj's scientific interests were especially focused on allergies, exanthemas, skin tuberculosis, and keratodermas...
December 2023: Acta Dermatovenerologica Croatica: ADC
https://read.qxmd.com/read/38439721/atorvastatin-induced-lupus-erythematosus-tumidus-a-case-report-and-literature-review
#23
REVIEW
Katarina Trčko, Nuša Lukinovič, Boštjan Luzar
Lupus erythematosus tumidus (LET) is a rare photosensitive skin disease classified as a separate subtype of cutaneous lupus erythematosus. Clinically, it is characterized by erythematous plaques on sun-exposed areas. Typical histopathological findings are perivascular and periadnexal lymphohistiocytic infiltrates and prominent mucin deposition in the dermis. Treatment is based on photoprotection, topical corticosteroids, and antimalarial drugs. The exact pathogenesis of the disease is unknown. Drugs are considered a minor risk factor for the development of LET...
December 2023: Acta Dermatovenerologica Croatica: ADC
https://read.qxmd.com/read/38439720/hypersensitivity-reactions-to-homemade-topical-preparations
#24
JOURNAL ARTICLE
Mislav Rončević, Katarina Radas, Suzana Ljubojević Hadžavdić
Homemade topical preparations are becoming increasingly popular due to the widespread belief that herbal and natural products are a safer and better option in the treatment of various conditions. However, homemade topical preparations can precipitate allergic and irritant reactions, depending on the herbal composition of the preparation. Hypersensitivity reactions to such preparations range from contact allergic dermatitis, contact irritant dermatitis, contact urticaria, toxic reaction, photosensitivity, and phototoxic reaction...
December 2023: Acta Dermatovenerologica Croatica: ADC
https://read.qxmd.com/read/38006375/flat-warts-verrucae-planae-confined-to-the-pigment-of-a-tattoo-a-rare-tattoo-associated-complication
#25
JOURNAL ARTICLE
Nika Filipović, Davor Tomas, Marija Buljan
Tattoos are a form of decorative body art in which pigment dyes of different colors are inoculated into the skin. It is estimated that 15-25% of general population has one or more tattoos (1), and the reasons for the popularity of this procedure may include greater social acceptance, aesthetic appeal, or perhaps the option of using laser removal techniques to eliminate unwanted tattoos. Even though modern professional tattoos are usually performed in sterile conditions, complications still occur, and with increasing numbers of people getting tattoos, the incidence of tattoo-associated side-effects presenting to dermatologists, which may be as high as 2%, is likely to increase (2)...
November 2023: Acta Dermatovenerologica Croatica: ADC
https://read.qxmd.com/read/38006374/dermatoscopic-features-of-early-erythema-chronicum-migrans
#26
JOURNAL ARTICLE
Yunus Ozcan, Sumeyye Gunes Takir, Ebru Karagun, Belkiz Uyar
Dear Editors, A 37-year-old man from a Lyme disease-endemic area presented with a one-week old rapidly expanding rash on his right calf. He lacked other comorbidities or symptoms such as fever, weakness, lack of appetite, or joint pain, but recalled removing a tick from the same region three weeks earlier. Inspection revealed a round, bluish-red erythematous patch with a central clearing (Figure 1). The patient experienced no discomfort, but the rash was warm and faded easily when palpated. Dermatoscopic inspection revealed collarette-shaped white scales encircling the punctum of the tick bite in the center (Figure 2, left inset)...
November 2023: Acta Dermatovenerologica Croatica: ADC
https://read.qxmd.com/read/38006373/papa-syndrome-challenges-in-achieving-long-term-remission
#27
JOURNAL ARTICLE
Hana Smajlović, Asja Prohić
For over two decades, the acronym PAPA syndrome has been used to describe an autoinflammatory condition caused by missense mutations in the PSTPIP1 (proline-serine-threonine phosphatase interacting protein 1) gene and clinically characterized by the presence of pyogenic arthritis, pyoderma gangrenosum (PG), and acne (1,2). Due to the involvement of the PSTPIP1 gene in the regulation of innate immunity, mutations of this gene cause abnormal activation of inflammasomes, complexes of NLRP3/ASC/caspase-1 proteins...
November 2023: Acta Dermatovenerologica Croatica: ADC
https://read.qxmd.com/read/38006372/erythrodermic-presentation-of-atopic-dermatitis-in-a-patient-with-secondary-adrenal-insufficiency-caused-by-oral-glucocorticosteroid-abuse
#28
JOURNAL ARTICLE
Alicja Mesjasz, Magdalena Trzeciak, Jowita Sroka-Tomaszewska, Anna Zaryczańska, Roman J Nowicki
Dear Editor, A 41-year-old man presented to the Department of Dermatology for the first time due to an exacerbation of atopic dermatitis (AD) in the form of erythroderma. The patient had a history of atopic diseases, with being AD active from infancy. On clinical examination, generalized erythematous skin lesions causing acute pruritus and accompanied by severe skin exfoliation and dryness were present. On closer examination, the patient had a collection of signs and symptoms characterizing Cushing syndrome that included a round and full face (''moon face''), supraclavicular fat pads, and proximal muscle atrophy...
November 2023: Acta Dermatovenerologica Croatica: ADC
https://read.qxmd.com/read/38006371/frank-s-sign-a-link-between-dermatovenerology-cardiac-pathology-and-neurology
#29
JOURNAL ARTICLE
Denis Čerimagić
Dear Editor, Although some of my colleagues may find this surprising, as a neurologist, I have noticed many connections between dermatology and neurology. Neurological and dermatological signs and symptoms are common in many clinical entities, especially in the so-called phakomatoses or neurocutaneous syndromes (Von Recklinghausen's disease type 1 and 2, Bourneville-Pringle syndrome, Sturge-Weber syndrome, Von Hippel-Lindau syndrome, Louis-Bar syndrome) (1). The terms "neurodermatitis" and "neurodermatology" also confirm the above...
November 2023: Acta Dermatovenerologica Croatica: ADC
https://read.qxmd.com/read/38006370/folliculotropism-in-actinic-keratoses-in-patients-not-responding-to-treatments-a-pilot-study
#30
JOURNAL ARTICLE
Emi Dika, Emi Dika, Martina Lambertini, Emi Dika, Martina Lambertini, Giulia Veronesi, Cosimo Misciali, Massimo Milani, Aleksandra Bergant-Suhodolcan, Bor Hrvatin Stancic, Carlotta Baraldi
Dear Editor, Actinic keratoses (AK) have a high prevalence in the general population, with greater rates in Caucasian patients after the fourth and fifth decades of life (37.5-60.0%) (1,2). Standard histopathologic reporting of AKs does not provide information on the presence of atypical keratinocytes extending to the hair follicle, also defined as folliculotropism (FLC). Commonly, atypical cells in AKs do not present FLC, but this feature can be observed in bowenoid AKs with full-thickness epidermal atypia (3,4)...
November 2023: Acta Dermatovenerologica Croatica: ADC
https://read.qxmd.com/read/38006369/aulus-cornelius-celsus-de-medicina-and-his-contributions-to-knowledge-on-skin-diseases
#31
JOURNAL ARTICLE
Franjo Gruber
The book De Medicina by Aulus Cornelius Celsus was the first complete treatise about medicine written in Latin. We know little about his life. The monography consists of eight books describing all that was known within the whole sphere of medicine and surgery in the first century AD. In the introduction (proemium), he also described the history of medicine until his time and also delineated the treatment of diseases that may be dietetic, medication-based or surgical. The treatise describes approximately forty skin diseases in a concise and clear style...
November 2023: Acta Dermatovenerologica Croatica: ADC
https://read.qxmd.com/read/38006368/prognostic-value-of-lactate-dehydrogenase-in-patients-with-melanoma-treated-with-pembrolizumab
#32
JOURNAL ARTICLE
Aleksandar Popović, Ivan Petković, Aleksandra Dimitrijevic, Andrija Jović
INTRODUCTION: Elevated LDH levels have been extensively reported as a biomarker of poorer outcome in patients with melanoma during the chemotherapeutic era. The role of LDH level as a prognostic factor for treatment outcomes in patients with metastatic melanoma treated with immunooncological therapy has also been reported but requires further analysis. OBJECTIVES: In this study, we aimed to evaluate the prognostic value of lactate dehydrogenase (LDH) among patients with metastatic and unresectable melanoma treated with pembrolizumab in terms of progression-free survival (PFS)...
November 2023: Acta Dermatovenerologica Croatica: ADC
https://read.qxmd.com/read/38006367/alterations-in-inflammation-markers-due-to-disease-activation-in-autoimmune-bullous-diseases
#33
JOURNAL ARTICLE
Gokhan Sahin, Esra Pancar Yuksel, Fatma Aydin
BACKGROUND: In the pathogenesis of autoimmune bullous diseases, there is an underlying autoinflammation against epidermal/subepidermal structures caused by many inflammatory cells. Aim / Objectives: In this study, we aimed to determine the alterations in inflammatory markers regarding disease activity in autoimmune bullous diseases and to discuss their contribution to the pathogenesis. METHODS: A total of 191 patients with pemphigus vulgaris (PV) and 46 patients with bullous pemphigoid (BP) who were admitted to the outpatient clinic at the Department of Dermatology were included...
November 2023: Acta Dermatovenerologica Croatica: ADC
https://read.qxmd.com/read/38006366/the-role-of-t-follicular-helper-cells-in-clinical-remission-and-relapse-in-patients-with-pemphigus-treated-with-rituximab
#34
JOURNAL ARTICLE
Ayşe Akman Karakaş, Erkan Ergün, Nurten Sayın Ekinci, Aslı Toylu, Soner Uzun, Erkan Alpsoy
BACKGROUND: Pemphigus is a rare chronic autoimmune disease. Recent studies have found that T follicular helper (Tfh) cells may play a role in autoimmune diseases. In this study, Tfh cells frequency, BCL6 gene expression, IL-21, and IL-6 cytokines levels were examined, with the aim of understanding the effect of RTX on these cells in the onset of clinical remission or relapse in patients with pemphigus. METHODS: 20 patients with pemphigus vulgaris and 20 healthy controls without any autoimmune diseases that were admitted to the Dermatology and Venereology Clinic of the Akdeniz University Hospital were included...
November 2023: Acta Dermatovenerologica Croatica: ADC
https://read.qxmd.com/read/38006365/the-impact-of-blue-light-irradiation-on-keratinocytes-in-vitro
#35
JOURNAL ARTICLE
Markus Denzinger, Andreas K Nüssler, Fabian Medved, Sabrina Krauß, Adrien Daigeler, Manuel Held, Claudius Illg
BACKGROUND: This study examined the effects of irradiation with blue light on HaCaT keratinocytes. As irradiation with blue light is known to be antimicrobial, it offers a promising alternative therapy for contaminated wounds. There is evidence that red light promotes wound healing, but the potential benefits of irradiation with blue light have not yet been adequately investigated. METHODS: The rate of wound closure in sterile and contaminated cells was measured using an in vitro scratch assay wound-healing model...
November 2023: Acta Dermatovenerologica Croatica: ADC
https://read.qxmd.com/read/38006364/insulin-growth-factor-1-status-in-hidradenitis-suppurativa-a-french-institutional-pilot-study
#36
JOURNAL ARTICLE
Perrine Rousseau, Alexandra Poinas, Damien Masson, Kalyane Bach-Ngohou, Michel Nguyen, Marie Le Moigne, Barbara Bregeon, Florence Vrignaud, Amir Khammari, Brigitte Dréno
BACKGROUND: Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease of the follicles in the apocrine glands and is associated with a deficiency in the innate immunity of the skin. It is characterized by the occurrence of nodules, abscesses, fistulas, scars. OBJECTIVE: Although a relationship has already been demonstrated between HS and innate immunity, IGF-1 status in patients with HS is still unknown. The objective of this pilot study was to determine IGF-1 status in patients with HS as well as its potential relationship with the clinical profile of the disease...
November 2023: Acta Dermatovenerologica Croatica: ADC
https://read.qxmd.com/read/37843094/the-leser-tr%C3%A3-lat-sign-in-a-patient-with-gastric-adenocarcinoma
#37
JOURNAL ARTICLE
Antonela Geber, Ayla Hadžavdić, Suzana Ljubojević Hadžavdić
Dear Editor, The Leser-Trélat sign is a rare paraneoplastic cutaneous marker of internal malignancy characterized by sudden eruption of multiple seborrheic keratoses (SK). It is mostly associated with gastrointestinal adenocarcinomas (gastric, colon, rectal), and less frequently with breast cancer and lymphoproliferative disorders/lymphoma (1). It can be also associated with lung, kidney, liver, and pancreas malignancy (1). Pruritus occurs in half of the patients. Lesions rarely require any treatment, as they mostly tend to resolve once management of the underlying malignancy has started (2)...
August 2023: Acta Dermatovenerologica Croatica: ADC
https://read.qxmd.com/read/37843093/brodalumab-seems-to-recover-its-therapeutic-efficacy-after-a-relatively-short-washout-period-with-anti-tnf-agents-a-successful-pattern-for-double-switch-therapy
#38
MULTICENTER STUDY
Eleftheria Tampouratzi, Konstantinos Sfaelos, Kyriakos Talaiporou, Τheodora Douvali, John Katsantonis
Psoriasis is a lifelong disease with a chronic relapsing course, and treatment agent switching is a common and accepted practice in cases of primary or secondary inadequate response. Patients with prior biologic treatment failure or loss of response are a subset of individuals who most likely have more severe disease with a greater impact on quality of life. Additionally, switching between multiple biologics is associated with clinical consequences (e.g. development of anti-drug antibodies), which may limit efficacy of subsequent biologic therapies (1,2)...
August 2023: Acta Dermatovenerologica Croatica: ADC
https://read.qxmd.com/read/37843092/morphea-after-silicone-implants
#39
JOURNAL ARTICLE
Uwe Wollina, Jacqueline Schönlebe
Dear Editor, Silicone is a hydrophobic polymer containing silicon. Silicon is an essential compound of soft tissue proteoglycans. Reports about morphea and other autoimmune connective tissue disorders in association with silicone implants have stimulated the discussion of a possible link between the two, such as immunological cross-reactivity of silicone and connective tissue components (1). A number of case reports suggested a possible link to adjuvant autoimmune syndrome (2), morphea of the breast (3-5), and systemic scleroderma (6-8), among others...
August 2023: Acta Dermatovenerologica Croatica: ADC
https://read.qxmd.com/read/37843091/pemphigus-vegetans-of-hallopeau-a-case-report
#40
JOURNAL ARTICLE
Jelena Maljić, Jaka Radoš, Davorin Lončarić, Ines Lakoš Jukić
Dear Editor, Pemphigus vegetans (PV) of Hallopeau is a rare and indolent variant of pemphigus clinically characterized by vegetating lesions preceded by pustules mainly in flexural areas (1,2). This helps us to differentiate it from PV of Neumann, which is a more extensive and refractory disease, more alike to a pemphigus vulgaris outbreak with blisters which turn into vegetating plaques (3). We report the clinical presentation, course, and therapeutic response in a patient diagnosed with PV of Hallopeau from its early stage during a 3-year follow up...
August 2023: Acta Dermatovenerologica Croatica: ADC
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