Aleksey Ogurtsov, Gelio Alves, Alex Rubio, Brendan Joyce, Björn Andersson, Roger Karlsson, Edward R B Moore, Yi-Kuo Yu
Although many user-friendly workflows exist for identifications of peptides and proteins in mass-spectrometry-based proteomics, there is a need of easy to use, fast, and accurate workflows for identifications of microorganisms, antimicrobial resistant proteins, and biomass estimation. Identification of microorganisms is a computationally demanding task that requires querying thousands of MS/MS spectra in a database containing thousands to tens of thousands of microorganisms. Existing software can't handle such a task in a time efficient manner, taking hours to process a single MS/MS experiment...
February 2, 2024: Journal of Computational Biology