Feihong Dong, Jian An, Wenyu Guo, Jie Dang, Shuo Huang, Feng Feng, Jiabin Zhang, Di Wang, Jingyi Yin, Jing Fang, Heping Cheng, Jue Zhang
Ultrasound-stimulated contrast agents have gained significant attention in the field of tumor treatment as drug delivery systems. However, their limited drug-loading efficiency and the issue of bulky, imprecise release have resulted in inadequate drug concentrations at targeted tissues. Herein, we developed a highly efficient approach for doxorubicin (DOX) precise release at tumor site and real-time feedback via an integrated strategy of "programmable ultrasonic imaging guided accurate nanodroplet destruction for drug release" (PND)...
March 24, 2024: Ultrasonics Sonochemistry