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Journals Menopause : the Journal of the...

Menopause : the Journal of the North American Menopause Society

https://read.qxmd.com/read/38888619/menopause-and-brain-fog-how-to-counsel-and-treat-midlife-women
#1
JOURNAL ARTICLE
Pauline M Maki, Nicole G Jaff
Brain fog, referring to menopause-related subjective cognitive difficulties, is common in midlife women. Longitudinal studies find small but reliable declines in objective memory performance as women transition into perimenopause, and these are not explained by advancing age alone. When memory declines occur, performance levels remain within normal limits for all but a very small number of women. Women's experience of brain fog extends beyond memory complaints, reflecting the negative effect on a broad range of cognitive abilities...
June 17, 2024: Menopause: the Journal of the North American Menopause Society
https://read.qxmd.com/read/38860942/cognitive-function-and-bladder-health-among-midlife-adult-women-in-the-coronary-artery-risk-development-in-young-adults-cardia-study
#2
JOURNAL ARTICLE
Sonya S Brady, Andrés Arguedas, Jared D Huling, Gerhard Hellemann, Kristine Yaffe, Cora E Lewis, Cynthia S Fok, Stephen K Van Den Eeden, Alayne D Markland
OBJECTIVE: The aim of this study was to examine whether different aspects of women's cognitive function are associated with lower urinary tract symptoms (LUTS) and their impact. METHODS: In 2010-2011, women aged 42 to 57 years in the Coronary Artery Risk Development in Young Adults study completed different tests of cognitive function, including the Digit Symbol Substitution Test, Rey Auditory Verbal Learning Test, and Stroop test. Two years later, data on LUTS and their impact were collected...
June 11, 2024: Menopause: the Journal of the North American Menopause Society
https://read.qxmd.com/read/38860940/individual-and-additive-effect-relationships-of-menopausal-symptoms-and-subjective-cognitive-decline-among-nurses-during-menopausal-transition-a-cross-sectional-study
#3
JOURNAL ARTICLE
Xudong He, Fangyan Hou, Xiaona Shen, Di Zhao, Xiangyu Zhao, Meiling Qi, Ping Li
OBJECTIVE: This study aimed to examine the individual and additive-effect relationships between menopausal symptoms and subjective cognitive decline among nurses during menopausal transition. METHODS: Between February and September 2019, a convenience sampling strategy was used, involving 1,335 Chinese nurses undergoing menopausal transition. A general information survey that included the Subjective Cognitive Decline Scale and the Menopause Rating Scale was completed...
June 11, 2024: Menopause: the Journal of the North American Menopause Society
https://read.qxmd.com/read/38860935/a-novel-objective-evaluation-method-shear-wave-elastography-in-the-treatment-of-atrophic-vaginitis-by-nonablative-intravaginal-er-yag-laser-a-randomized-sham-controlled-pilot-study
#4
JOURNAL ARTICLE
Elif Bayraktar, C Tamer Erel, Hayedeh Akturk, Ipek Betul Ozcivit Erkan, Rauf Hamid, Ebru Alper, Ibrahim Adaletli, Mert Urfalioglu
OBJECTIVE: The aim of the study was to investigate the effectiveness of intravaginal Er:YAG laser for treating atrophic vaginitis in postmenopausal women utilizing shear wave elastography. METHODS: In this prospective randomized sham-controlled double-blind pilot study, 20 participants were included (laser group [n = 12] / sham-control group [n = 8]). A nonablative (Smooth mode) Er:YAG laser with a wavelength of 2,940 nm was used. Objective evaluation of laser treatment efficacy was conducted using a special ultrasonic technique: shear wave elastography...
June 11, 2024: Menopause: the Journal of the North American Menopause Society
https://read.qxmd.com/read/38860933/quality-of-life-in-postmenopausal-women-and-its-association-with-sarcopenia
#5
JOURNAL ARTICLE
Nikitha Sriramaneni, Chitra Selvan, Nanda Kumar S, Pramila Kalra, Ganavi Y P, Manjunath P R, Altaf Ali Naushad, Sagar Sourabh, Chirag L U
OBJECTIVES: With the menopausal transition, there is a decline in estrogen concentration with potential health consequences affecting the quality of life. The loss of muscle mass, strength, and function, known as sarcopenia is common in postmenopausal women. The primary objective of this study is to assess the quality of life in postmenopausal women and its association with sarcopenia. METHODS: This was a cross-sectional study conducted in 106 postmenopausal women...
June 11, 2024: Menopause: the Journal of the North American Menopause Society
https://read.qxmd.com/read/38860931/relationship-between-menopausal-hormone-therapy-and-colorectal-cancer-a-cohort-study-utilizing-the-health-insurance-database-in-south-korea-hisk-ii
#6
JOURNAL ARTICLE
Jin-Sung Yuk, Ji Hyun Noh, Myoung Hwan Kim, Gwan Hee Han, Jungbin Kim, Hyunjin Cho, Geumhee Gwak, Yujin Lee
OBJECTIVE: Many studies have demonstrated that menopausal hormone therapy is associated with a reduced risk for colorectal cancer. This study investigated the relationship between specific hormone therapy regimens and colorectal cancer risk in postmenopausal women in South Korea using national insurance claims data. METHODS: This population-based, retrospective cohort study used insurance data provided by the Health Insurance Review and Assessment Service between 2007 and 2020...
June 11, 2024: Menopause: the Journal of the North American Menopause Society
https://read.qxmd.com/read/38860929/chronic-kidney-disease-in-postmenopausal-women-is-associated-with-tooth-loss
#7
JOURNAL ARTICLE
Na-Yeong Kim, Ji-Eun Kim, Choong-Ho Choi, Ki-Ho Chung
OBJECTIVE: Menopause is characterized by changes in reproductive hormone levels that can negatively affect bone. Chronic kidney disease (CKD) and tooth loss are also important and common health issues after menopause. This study aimed to evaluate the association between CKD and tooth loss in postmenopausal women. METHODS: The study evaluated 64,971 participants who participated in the Korean National Health and Nutrition Examination Survey (KNHANES) from 2010-2018, including postmenopausal women, aged 40 to 79 years...
June 11, 2024: Menopause: the Journal of the North American Menopause Society
https://read.qxmd.com/read/38814194/association-between-triglyceride-glucose-index-and-femoral-bone-mineral-density-in-community-dwelling-nondiabetic-men-and-women-a-nhanes-analysis-of-1-928-us-individuals
#8
JOURNAL ARTICLE
Hailing Chen, Jianpeng Hu, Jufen Li, Quan Li, Ling Lan
OBJECTIVE: To determine the potential association between the triglyceride-glucose (TyG) index and bone mineral density (BMD) in community-dwelling adults without diabetes using a nationally representative database from the United States (US). METHODS: Data were extracted from the National Health and Nutrition Examination Survey (NHANES) 2005-2010, 2013-2014, and 2017-2018. Men and postmenopausal women aged ≥50 years with complete data on femoral neck BMD, triglycerides, and fasting plasma glucose levels were eligible for inclusion...
May 28, 2024: Menopause: the Journal of the North American Menopause Society
https://read.qxmd.com/read/38814193/acute-increases-in-physical-activity-and-temperature-are-associated-with-hot-flash-experience-in-midlife-women
#9
JOURNAL ARTICLE
Sarah Witkowski, Quinn White, Sofiya Shreyer, Randi L Garcia, Daniel E Brown, Lynnette Leidy Sievert
OBJECTIVE: This study determined the association between acute changes in physical activity, temperature, and humidity and 24-hour subjective and objective hot flash experience. METHODS: Data collection occurred during the cooler months of the year in Western Massachusetts (October-April). Women aged 45-55 across three menopause stages (n = 270) were instrumented with ambulatory monitors to continuously measure hot flashes, physical activity, temperature, and humidity for 24 hours...
May 28, 2024: Menopause: the Journal of the North American Menopause Society
https://read.qxmd.com/read/38743912/physical-activity-to-reduce-the-burden-of-frailty-after-menopause-effectiveness-and-adherence-rate-of-a-resource-saving-exercise-plan
#10
JOURNAL ARTICLE
Alicia García-Vigara, Julio Fernandez-Garrido, Juan-Antonio Carbonell-Asíns, M Luz Sánchez-Sánchez, Aitana Monllor-Tormos, Miguel-Ángel García-Pérez, Juan J Tarín, Antonio Cano
OBJECTIVE: Frailty may be increased by menopause. Physical activity has been proposed to reduce frailty, but poor adherence and cost limit effectiveness. We aimed to investigate both the effectiveness against the frailty burden and the adherence rate of a multicomponent physical activity scheme partially managed by the participating women themselves. METHODS: Prospective controlled study consisting of a twice-weekly group physical activity scheme divided into two consecutive periods, one supervised by a health professional (12 wk) and the other supervised by the women themselves (36 wk)...
May 14, 2024: Menopause: the Journal of the North American Menopause Society
https://read.qxmd.com/read/38743910/high-density-lipoprotein-metrics-during-midlife-and-future-subclinical-atherosclerosis-in-women-the-swan-hdl-study
#11
JOURNAL ARTICLE
Alexis Nasr, Maria M Brooks, Emma Barinas-Mitchell, Trevor Orchard, Jeffrey Billheimer, Norman C Wang, Daniel McConnell, Daniel J Rader, Samar R El Khoudary
OBJECTIVE: The clinical utility of high-density lipoprotein cholesterol (HDL-C) in risk classification is limited, especially in midlife women. Novel metrics of HDL may better reflect this risk. We clustered a comprehensive profile of HDL metrics into favorable and unfavorable clusters and assessed how these two clusters are related to future subclinical atherosclerosis (carotid intima media thickness [cIMT], interadventitial diameter [IAD], and carotid plaque presence) in midlife women...
May 14, 2024: Menopause: the Journal of the North American Menopause Society
https://read.qxmd.com/read/38743907/recommended-measurement-instruments-for-genitourinary-symptoms-associated-with-menopause-the-comma-core-outcomes-in-menopause-consortium
#12
JOURNAL ARTICLE
Vincent S Paramanandam, Sarah Lensen, Michaela Gabes, Gesina Kann, Theresa Donhauser, Niamh F Waters, Anna D Li, Michelle Peate, Nipuni S Susanto, Lucy E Caughey, Fatema Rangoonwal, Jingbo Liu, Patrick Condron, Ismaila Aberi Obalowu, David F Archer, Robin J Bell, Monica Christmas, Melanie Davies, Susan R Davis, Karen Giblin, Stamatina Iliodromiti, Unnop Jaisamrarn, Sunila Khandelwal, Ludwig Kiesel, Neelam Aggarwal, Caroline M Mitchell, Gita D Mishra, Rossella E Nappi, Nick Panay, Helen Roberts, Serge Rozenberg, Jan Shifren, James A Simon, Petra Stute, Amanda J Vincent, Wendy Wolfman, Martha Hickey
OBJECTIVE: The aim of the study is to identify appropriate definitions and patient-reported outcome measures (PROMs) for each of the eight core outcomes previously selected for genitourinary symptoms associated with menopause: pain with sex, vulvovaginal dryness, vulvovaginal discomfort or irritation, discomfort or pain when urinating, change in most bothersome symptom, distress, bother or interference of genitourinary symptoms, satisfaction with treatment, and side effects. METHODS: We conducted a systematic review to identify possible definitions and PROMs, including their measurement properties...
May 14, 2024: Menopause: the Journal of the North American Menopause Society
https://read.qxmd.com/read/38713891/association-between-vaginal-microbiota-and-vaginal-inflammatory-immune-markers-in-postmenopausal-women
#13
JOURNAL ARTICLE
Elizabeth H Byrne, Hoseung Song, Sujatha Srinivasan, David N Fredricks, Susan D Reed, Katherine A Guthrie, Michael Wu, Caroline M Mitchell
OBJECTIVE: In premenopausal individuals, vaginal microbiota diversity and lack of Lactobacillus dominance are associated with greater mucosal inflammation, which is linked to a higher risk of cervical dysplasia and infections. It is not known if the association between the vaginal microbiota and inflammation is present after menopause, when the vaginal microbiota is generally higher-diversity and fewer people have Lactobacillus dominance. METHODS: This is a post hoc analysis of a subset of postmenopausal individuals enrolled in a randomized trial for treatment of moderate-severe vulvovaginal discomfort that compared vaginal moisturizer, estradiol, or placebo...
May 7, 2024: Menopause: the Journal of the North American Menopause Society
https://read.qxmd.com/read/38713886/evaluating-the-effects-of-hormone-therapy-termination-on-skeletal-muscle-and-physical-independence-in-postmenopausal-women
#14
JOURNAL ARTICLE
Jorgen Antonin Wullems, Hans Degens, Christopher Ian Morse, Gladys Leopoldine Onambélé-Pearson
OBJECTIVE: In women, the age-related decline in skeletal muscle structure and function is accelerated after menopause, which implicates the role of decreased circulating estrogen levels. Indeed, boosting estrogen, by means of postmenopausal hormone therapy (HT), generally proves beneficial to skeletal muscle. The evidence regarding whether these benefits persist even after cessation of HT is limited, nor is it clear how physical behavior (PB) impacts on benefits. Hence, this exploratory study focused on the interplay between HT administration/cessation, PB and in vivo skeletal muscle structure and function...
May 7, 2024: Menopause: the Journal of the North American Menopause Society
https://read.qxmd.com/read/38688467/gray-matter-volume-in-women-with-the-brca-mutation-with-and-without-ovarian-removal-evidence-for-increased-risk-of-late-life-alzheimer-s-disease-or-dementia
#15
JOURNAL ARTICLE
Suzanne T Witt, Alana Brown, Laura Gravelsins, Maria Engström, Elisabet Classon, Nina Lykke, Elisabeth Åvall-Lundqvist, Elvar Theordorsson, Jan Ernerudh, Preben Kjölhede, Gillian Einstein
OBJECTIVE: Ovarian removal prior to spontaneous/natural menopause (SM) is associated with increased risk of late life dementias including Alzheimer's disease. This increased risk may be related to the sudden and early loss of endogenous estradiol. Women with breast cancer gene mutations (BRCAm) are counseled to undergo oophorectomy prior to SM to significantly reduce their risk of developing breast, ovarian, and cervical cancers. There is limited evidence of the neurological effects of ovarian removal prior to the age of SM showing women without the BRCAm had cortical thinning in medial temporal lobe structures...
April 30, 2024: Menopause: the Journal of the North American Menopause Society
https://read.qxmd.com/read/38688466/associations-of-anti-m%C3%A3-llerian-hormone-levels-among-women-in-their-mid-30s-with-menopausal-symptoms-14-years-later
#16
JOURNAL ARTICLE
Jasmin Mahabamunuge, Siwen Wang, Sheryl L Rifas-Shiman, Sabrina Faleschini, Victoria W Fitz, Jan Shifren, Jorge E Chavarro, Emily Oken, Marie-France Hivert
OBJECTIVE: The aim of this study was to examine associations of anti-Müllerian hormone (AMH) levels in gravid women in their mid-30s with menopausal symptoms ~14 years later and age at natural menopause. METHODS: In this prospective analysis, 474 participants in Project Viva, a longitudinal cohort, were enrolled during pregnancy between 1999 and 2002. AMH levels were determined using plasma samples collected 3 years postpartum. Participants completed the Menopause Rating Scale (MRS) and self-reported age at and reason for menopause at the 17 years postpartum visit (Mid-Life Visit)...
April 30, 2024: Menopause: the Journal of the North American Menopause Society
https://read.qxmd.com/read/38688464/recommended-measurement-instruments-for-menopausal-vasomotor-symptoms-the-comma-core-outcomes-in-menopause-consortium
#17
JOURNAL ARTICLE
Sarah Lensen, Vincent S Paramanandam, Michaela Gabes, Gesina Kann, Theresa Donhauser, Niamh F Waters, Anna D Li, Michelle Peate, Nipuni S Susanto, Lucy E Caughey, Fatema Rangoonwal, Jingbo Liu, Patrick Condron, Panagiotis Anagnostis, David F Archer, Nancy E Avis, Robin J Bell, Janet S Carpenter, Peter Chedraui, Monica Christmas, Melanie Davies, Tim Hillard, Myra S Hunter, Stamatina Iliodromiti, Nicole G Jaff, Unnop Jaisamrarn, Hadine Joffe, Sunila Khandelwal, Ludwig Kiesel, Pauline M Maki, Gita D Mishra, Rossella E Nappi, Nick Panay, Amos Pines, Helen Roberts, Serge Rozenberg, Camilo Rueda, Jan Shifren, James A Simon, Paul Simpson, Muhammad Fidel Ganis Siregar, Petra Stute, Joan Tan Garcia, Amanda J Vincent, Wendy Wolfman, Martha Hickey
OBJECTIVE: The aim of the study is to identify suitable definitions and patient-reported outcome measures (PROMs) to assess each of the six core outcomes previously identified through the COMMA (Core Outcomes in Menopause) global consensus process relating to vasomotor symptoms: frequency, severity, distress/bother/interference, impact on sleep, satisfaction with treatment, and side effects. METHODS: A systematic review was conducted to identify relevant definitions for the outcome of side-effects and PROMs with acceptable measurement properties for the remaining five core outcomes...
April 30, 2024: Menopause: the Journal of the North American Menopause Society
https://read.qxmd.com/read/38688462/association-of-muscle-disorders-in-late-postmenopausal-women-according-to-the-type-of-experienced-menopause
#18
JOURNAL ARTICLE
María S Vallejo, Juan E Blümel, Peter Chedraui, Konstantinos Tserotas, Carlos Salinas, Marcio A Rodrigues, Doris A Rodríguez, Claudia Rey, Eliana Ojeda, Mónica Ñañez, Álvaro Monterrosa-Castro, Gustavo Gómez-Tabares, María T Espinoza, Carlos Escalante, Alejandra Elizalde, Maribel Dextre, Andrés Calle, Sócrates Aedo
OBJECTIVE: Musculoskeletal disorders frequently affect postmenopausal women. This study aims to compare muscle disorders between women according to the type of experienced menopause: premature (PM) or normal age of menopause (NAM). METHODS: This was a cross-sectional study conducted in nine Latin American countries in which late postmenopausal women (55 to 70 years) were surveyed with a general questionnaire, the Menopause Rating Scale (MRS: item #4 exploring musculoskeletal discomfort), and the trength, assistance with walking, rising from a chair, climbing stairs, and falling questionnaire (risk of sarcopenia)...
April 30, 2024: Menopause: the Journal of the North American Menopause Society
https://read.qxmd.com/read/38652875/oral-lasofoxifene-s-effects-on-moderate-to-severe-vaginal-atrophy-in-postmenopausal-women-two-phase-3-randomized-controlled-trials
#19
JOURNAL ARTICLE
Risa Kagan, James A Simon, Steven R Goldstein, Barry S Komm, Simon N Jenkins, David J Portman
OBJECTIVE: The aim of this study was to demonstrate whether lasofoxifene improves vaginal signs/symptoms of genitourinary syndrome of menopause. METHODS: Two identical, phase 3 trials randomized postmenopausal women with moderate to severe vaginal symptoms to oral lasofoxifene 0.25 or 0.5 mg/d, or placebo, for 12 week. Changes from baseline to week 12 in most bothersome symptom, vaginal pH, and percentages of vaginal parabasal and superficial cells were evaluated...
April 23, 2024: Menopause: the Journal of the North American Menopause Society
https://read.qxmd.com/read/38652870/the-association-of-race-ethnicity-and-socioeconomic-status-on-the-severity-of-menopause-symptoms-a-study-of-68-864-women
#20
JOURNAL ARTICLE
Alison Kochersberger, Aeowynn Coakley, Leah Millheiser, Jerrine R Morris, Claire Manneh, Alicia Jackson, Jennifer L Garrison, Eduardo Hariton
OBJECTIVE: This study aimed to evaluate if and how race, ethnicity, and socioeconomic status (SES) are associated with the severity of menopause symptoms in a large, diverse sample of women. METHODS: For this cross-sectional study conducted between March 24, 2019, and January 13, 2023, a total of 68,864 women were enrolled from the Evernow online telehealth platform. Participants underwent a clinical intake survey, which encompassed demographic information, detailed medical questionnaires, and a modified Menopause Rating Scale...
April 23, 2024: Menopause: the Journal of the North American Menopause Society
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