journal
https://read.qxmd.com/read/36961558/correction-characteristics-of-synchronous-and-metachronous-duodenal-tumors-and-association-with-colorectal-cancer-a-supplementary-analysis
#1
Yasushi Yamasaki, Motohiko Kato, Yoji Takeuchi, Shu Hoteya, Tsuneo Oyama, Satoru Nonaka, Shoichi Yoshimizu, Masao Yoshida, Ken Ohata, Yoshimasa Miura, Yuko Hara, Shigetsugu Tsuji, Osamu Dohi, Hiroya Ueyama, Koichi Kurahara, Tomoaki Tashima, Nobutsugu Abe, Toshiharu Mitsuhashi, Atsushi Nakayama, Ichiro Oda, Naohisa Yahagi
No abstract text is available yet for this article.
March 24, 2023: Journal of Gastroenterology
https://read.qxmd.com/read/36961557/new-insight-on-the-correlation-of-immune-landscapes-with-immune-markers-expression-in-different-risk-classification-of-gastrointestinal-stromal-tumors
#2
JOURNAL ARTICLE
Qiang Zhang, Xiangfei Sun, Yingyong Hou, Xiaodong Gao, Kuntang Shen, Xinyu Qin
BACKGROUND: The immune landscapes of gastrointestinal stromal tumors (GISTs) are still unclear. We aimed to explore the immune status of GISTs with different recurrence risks and sought potential immunotherapeutic targets. METHODS: Immune cell infiltration and the expression of 93 tumor markers of 65 GISTs with different recurrence risks from public datasets were analyzed via bioinformatic methods. Infiltrating immune cell and OX40L expression of 417 patients from the Zhongshan cohort were analyzed by immunohistochemistry and immunofluorescence...
March 24, 2023: Journal of Gastroenterology
https://read.qxmd.com/read/36961556/antidiabetic-drugs-for-ibd-a-long-but-promising-road-ahead-for-drug-repositioning-to-target-intestinal-inflammation
#3
EDITORIAL
Shinichiro Shinzaki, Toshiyuki Sato, Hirokazu Fukui
No abstract text is available yet for this article.
March 24, 2023: Journal of Gastroenterology
https://read.qxmd.com/read/36943530/plenectomy-and-azygoportal-disconnection-decreases-the-risk-of-hepatocellular-carcinoma-for-cirrhosis-patients-with-portal-hypertension-bleeding-a-10-year-retrospective-follow-up-study-based-on-the-inverse-probability-of-treatment-weighting-method
#4
JOURNAL ARTICLE
Tian-Ming Gao, Jie Zhou, Xiao-Xing Xiang, Sheng-Jie Jin, Jian-Jun Qian, Chi Zhang, Bao-Huan Zhou, Hua Tang, Dou-Sheng Bai, Guo-Qing Jiang
BACKGROUND: Liver cirrhosis is the highest risk factor for hepatocellular carcinoma (HCC) worldwide. However, etiological therapy is the only option in cirrhosis patients to decrease the HCC risk. The aim of this study was to explore whether laparoscopic splenectomy and azygoportal disconnection (LSD) decreases the risk of HCC for patients with cirrhotic portal hypertension (CPH). METHODS: Between April 2012 and April 2021, we identified 595 CPH patients in our hepatobiliary pancreatic center who were diagnosed with gastroesophageal variceal bleeding and secondary hypersplenism, and performed a 10-year retrospective follow-up...
March 21, 2023: Journal of Gastroenterology
https://read.qxmd.com/read/36935473/management-of-colorectal-high-grade-dysplasia-or-cancer-resected-by-cold-snare-polypectomy-a-multicenter-exploratory-study
#5
JOURNAL ARTICLE
Kazuya Inoki, Hiroyuki Takamaru, Hiroto Furuhashi, Yoshihiro Kishida, Yuichi Shimodate, Yorinobu Sumida, Kazuya Hosotani, Hiroya Ueyama, Yohei Furumoto, Shinichi Hashimoto, Yoji Takeuchi, Ryoji Ichijima, Yashiro Yoshizawa, Takuto Suzuki, Yosuke Minoda, Kazuhiro Mizukami, Tomoaki Matsumura, Toyotaka Kasai, Takeshi Yamamura, Ken Ohnita, Ken Hara, Mitsuru Esaki, Atsushi Katagiri, Hideki Ishikawa, Takuji Gotoda
BACKGROUND: The clinical course and surveillance strategy for patients who undergo cold snare polypectomy (CSP) for high-grade dysplasia (HGD) or cancer is unclear. We investigated the management of colorectal HGDs and cancers following CSP. METHODS: This Japanese nationwide multicenter exploratory study was retrospectively conducted on patients who had undergone CSP for colorectal HGDs or cancers and follow-up colonoscopy at least once from 2014 to 2020. We investigated the detection rate of CSP scars, local recurrence rate (LRR), risk factors for local recurrence, and follow-up strategy...
March 20, 2023: Journal of Gastroenterology
https://read.qxmd.com/read/36928343/high-risk-population-of-progressive-hepatic-fibrosis-in-chronic-hepatitis-b-patients-on-antiviral-therapy
#6
JOURNAL ARTICLE
Xiujuan Chang, Yinying Li, Chao Sun, Xiaodong Li, Wenjuan Du, Qinghua Shang, Laicheng Song, Qinghua Long, Qin Li, Huabao Liu, Jing Wang, Zujiang Yu, Jiang Li, Guangming Xiao, Li Li, Liang Chen, Lin Tan, Yongping Chen, Yongping Yang
BACKGROUND: Progressive hepatic fibrosis leads to hepatocellular carcinoma (HCC) and decompensated cirrhosis. The aim of this study was to identify the high-risk population for progressive hepatic fibrosis and the incidence of HCC and decompensated cirrhosis in chronic hepatitis B (CHB) patients with antiviral therapy. METHODS: The data came from a multicenter, center-randomized, double-blind clinical trial that analyzed only patients in the ETV-treated arm. There was 156 hepatitis B e antigen (HBeAg)-positive and 135 HBeAg-negative patients in 14 institutions...
March 16, 2023: Journal of Gastroenterology
https://read.qxmd.com/read/36899173/the-role-of-stromal-bmp-cxcl12-signaling-axis-in-serrated-polyp-development
#7
EDITORIAL
Munemasa Nagao, Akihisa Fukuda
No abstract text is available yet for this article.
March 11, 2023: Journal of Gastroenterology
https://read.qxmd.com/read/36894804/induction-therapy-with-hepatic-arterial-infusion-chemotherapy-enhances-the-efficacy-of-lenvatinib-and-pd1-inhibitors-in-treating-hepatocellular-carcinoma-patients-with-portal-vein-tumor-thrombosis
#8
JOURNAL ARTICLE
Yizhen Fu, Wei Peng, Weixiang Zhang, Zhenyun Yang, Zili Hu, Yanxun Pang, Dandan Hu, Jinbin Chen, Juncheng Wang, Zhongguo Zhou, Li Xu, Minshan Chen, Yaojun Zhang
BACKGROUND: Hepatic arterial infusion chemotherapy (HAIC) with fluorouracil, leucovorin, and oxaliplatin (FOLFOX), lenvatinib and programmed death receptor-1 signaling inhibitors (PD1s) all alone have been proven effective in treating advanced hepatocellular carcinoma (HCC), yet the efficacy and safety of the tri-combination therapy in treating HCC patients with portal vein tumor thrombosis (PVTT) remains unknown. METHODS: In this retrospective study, HCC patients with PVTT received either induction therapy of HAIC and lenvatinib plus PD1s in the initial period of treatment and then dual maintenance therapy of lenvatinib and PD1s (HAIC-Len-PD1) or continuous lenvatinib combined with PD1s (Len-PD1)...
March 9, 2023: Journal of Gastroenterology
https://read.qxmd.com/read/36892638/comparing-the-predictive-ability-of-portoatrial-and-portocaval-gradient-after-transjugular-intrahepatic-portosystemic-shunt-creation-for-variceal-rebleeding
#9
JOURNAL ARTICLE
Li Ma, Yaozu Liu, Zhiping Yan, Wen Zhang, Zihan Zhang, Minjie Yang, Jiaze Yu, Xin Zhou, Shiyao Chen, Jian Wang, Jingqin Ma, Jianjun Luo
BACKGROUND: Measuring the portal pressure gradient from the portal vein (PV) to the inferior vena cava (IVC) or to the right atrium (RA) remains controversial. The aim of our study was to compare the predictive ability of portoatrial gradient (PAG) and portocaval gradient (PCG) for variceal rebleeding. METHODS: The data of 285 cirrhotic patients with variceal bleeding undergoing elective transjugular intrahepatic portosystemic shunt (TIPS) in our hospital were analyzed retrospectively...
March 9, 2023: Journal of Gastroenterology
https://read.qxmd.com/read/36884074/correction-current-status-and-future-perspective-of-linked-color-imaging-for-gastric-cancer-screening-a-literature-review
#10
Kazuo Yashima, Takumi Onoyama, Hiroki Kurumi, Yohei Takeda, Akira Yoshida, Koichiro Kawaguchi, Naoyuki Yamaguchi, Hajime Isomoto
No abstract text is available yet for this article.
March 8, 2023: Journal of Gastroenterology
https://read.qxmd.com/read/36884073/correction-the-association-between-antigenemia-histology-with-immunohistochemistry-and-mucosal-pcr-in-the-diagnosis-of-ulcerative-colitis-with-concomitant-human-cytomegalovirus-infection
#11
Tsukasa Yamakawa, Hiroki Kitamoto, Masanori Nojima, Tomoe Kazama, Kohei Wagatsuma, Keisuke Ishigami, Shuji Yamamoto, Yusuke Honzawa, Minoru Matsuura, Hiroshi Seno, Hiroshi Nakase
No abstract text is available yet for this article.
March 8, 2023: Journal of Gastroenterology
https://read.qxmd.com/read/36884072/correction-lat1-expression-influences-paneth-cell-number-and-tumor-development-in-apc-min-mice
#12
Yunlong Sui, Namiko Hoshi, Ryuichi Ohgaki, Lingling Kong, Ryutaro Yoshida, Norihiro Okamoto, Masato Kinoshita, Haruka Miyazaki, Yuna Ku, Eri Tokunaga, Yuki Ito, Daisuke Watanabe, Makoto Ooi, Masakazu Shinohara, Kengo Sasaki, Yoh Zen, Takenori Kotani, Takashi Matozaki, Zibin Tian, Yoshikatsu Kanai, Yuzo Kodama
No abstract text is available yet for this article.
March 8, 2023: Journal of Gastroenterology
https://read.qxmd.com/read/36884071/clinical-outcome-of-ulcerative-colitis-with-severe-onset-in-children-a-multicenter-prospective-cohort-study
#13
JOURNAL ARTICLE
Ryusuke Nambu, Katsuhiro Arai, Takahiro Kudo, Takatsugu Murakoshi, Reiko Kunisaki, Tatsuki Mizuochi, Sawako Kato, Hideki Kumagai, Mikihiro Inoue, Takashi Ishige, Takeshi Saito, Atsuko Noguchi, Toshifumi Yodoshi, Shin-Ichiro Hagiwara, Naomi Iwata, Shigeo Nishimata, Fumihiko Kakuta, Hitoshi Tajiri, Eitaro Hiejima, Nariaki Toita, Takahiro Mochizuki, Hirotaka Shimizu, Itaru Iwama, Yuri Hirano, Toshiaki Shimizu
BACKGROUND: As best practices for treating children with severe-onset ulcerative colitis remain controversial in the era of biologic agents, we prospectively investigated treatments and outcomes in a multicenter cohort. METHODS: Using a Web-based data registry maintained in Japan between October 2012 and March 2020, we compared management and treatment outcomes in an S1 group defined by a Pediatric Ulcerative Colitis Activity Index of 65 or more points at diagnosis with those in an S0 group defined by an index value below 65...
March 8, 2023: Journal of Gastroenterology
https://read.qxmd.com/read/36867237/frequency-of-lymph-node-metastasis-according-to-tumor-location-in-clinical-t1-early-gastric-cancer-supplementary-analysis-of-the-japan-clinical-oncology-group-study-jcog0912
#14
JOURNAL ARTICLE
Yuji Akiyama, Hitoshi Katai, Ryo Kitabayashi, Souya Nunobe, Keisuke Koeda, Masahiro Yura, Yuya Sato, Takaki Yoshikawa, Masanori Terashima
BACKGROUND: The frequency of lymph node metastases per lymph node site in early gastric cancer has not been well clarified from the data based on prospective studies. This exploratory analysis aimed to determine the frequency and location of lymph node metastases in clinical T1 gastric cancer using the data from JCOG0912 to investigate the validity of the extent of standard lymph node dissection defined in Japanese guidelines. METHODS: This analysis included 815 patients with clinical T1 gastric cancer...
March 3, 2023: Journal of Gastroenterology
https://read.qxmd.com/read/36859628/rtp4-silencing-provokes-tumor-intrinsic-resistance-to-immune-checkpoint-blockade-in-colorectal-cancer
#15
JOURNAL ARTICLE
Yudai Yamamoto, Shu Shimada, Yoshimitsu Akiyama, Shu Tsukihara, Raizo Sugimoto, Ayano Kabashima, Masanori Tokunaga, Yusuke Kinugasa, Yutaka Kawakami, Shinji Tanaka
BACKGROUND: Recent advances in immune checkpoint blockade (ICB) have improved patient prognosis in mismatch repair-deficient and microsatellite instability-high colorectal cancer (dMMR/MSI-H CRC); however, PD-1 blockade has faced a challenge in early progressive disease. We aimed to understand the early event in ICB resistance using an in vivo model. METHODS: We subcutaneously transplanted the MC38 colon cancer cells into C57BL/6 mice, intraperitoneally injected anti-PD-1 antibody and then isolated ICB-resistant subclones from the recurrent tumors...
March 2, 2023: Journal of Gastroenterology
https://read.qxmd.com/read/36855000/diagnostic-criteria-and-endoscopic-and-histological-findings-of-autoimmune-gastritis-in-japan
#16
JOURNAL ARTICLE
Tomoari Kamada, Hidenobu Watanabe, Takahisa Furuta, Shuichi Terao, Yasuhiko Maruyama, Hiroshi Kawachi, Ryoji Kushima, Tsutomu Chiba, Ken Haruma
The Japanese diagnostic criteria for autoimmune gastritis (AIG) were established by the "Study Group on the establishment of diagnostic criteria for type A gastritis," which is related to a workshop associated with the Japan Gastroenterological Endoscopy Society (JGES) and the Committee of AIG Research Group (CARP). The criteria were set as follows: the cases of confirmed diagnosis are patients in whom either the endoscopic or histological findings, or both, meet the requirements for AIG and who are confirmed to be positive for gastric autoantibodies (either anti-parietal cell or anti-intrinsic factor antibodies, or both)...
March 1, 2023: Journal of Gastroenterology
https://read.qxmd.com/read/36847918/characteristics-of-synchronous-and-metachronous-duodenal-tumors-and-association-with-colorectal-cancer-a-supplementary-analysis
#17
JOURNAL ARTICLE
Yasushi Yamasaki, Motohiko Kato, Yoji Takeuchi, Shu Hoteya, Tsuneo Oyama, Satoru Nonaka, Shoichi Yoshimizu, Masao Yoshida, Ken Ohata, Yoshimasa Miura, Yuko Hara, Shigetsugu Tsuji, Osamu Dohi, Hiroya Ueyama, Koichi Kurahara, Tomoaki Tashima, Nobutsugu Abe, Toshiharu Mitsuhashi, Atsushi Nakayama, Ichiro Oda, Naohisa Yahagi
BACKGROUND: We previously reported outcomes of endoscopic resection for duodenal tumors in a large cohort. This study investigated the frequency and characteristics of synchronous and metachronous lesions, and their association with colorectal advanced adenoma (CAA) and colorectal cancer (CRC). METHODS: Patients underwent duodenal endoscopic resection during January 2008 to December 2018. Background and characteristics, incidence of synchronous and metachronous lesions, and incidence of CAA and CRC were investigated...
February 27, 2023: Journal of Gastroenterology
https://read.qxmd.com/read/36826475/acknowledgements
#18
JOURNAL ARTICLE
(no author information available yet)
No abstract text is available yet for this article.
February 24, 2023: Journal of Gastroenterology
https://read.qxmd.com/read/36790540/real-world-efficacy-and-safety-of-glecaprevir-pibrentasvir-in-japanese-adolescents-with-chronic-hepatitis-c-a-prospective-multicenter-study
#19
JOURNAL ARTICLE
Tatsuki Mizuochi, Itaru Iwama, Ayano Inui, Yoshinori Ito, Yugo Takaki, Sotaro Mushiake, Daisuke Tokuhara, Takashi Ishige, Koichi Ito, Jun Murakami, Haruka Hishiki, Hitoshi Mikami, Kazuhiko Bessho, Ken Kato, Ryosuke Yasuda, Yushiro Yamashita, Yasuhito Tanaka, Hitoshi Tajiri
BACKGROUND: Part 1 of the DORA study, a 2019 international clinical trial of glecaprevir and pibrentasvir (G/P) treatment in adolescents with chronic hepatitis C virus (HCV) infection, demonstrated high efficacy and safety. However, few reports have considered real-world experience with G/P treatment in adolescents with chronic HCV. The present prospective multicenter study assessed real-world efficacy and safety of G/P treatment in Japanese adolescents with chronic HCV. METHODS: Subjects between 12 and 17 years old who were treatment-naïve or previously managed with interferon-based regimens were prospectively enrolled and treated with G/P (300 mg/120 mg) once daily for 8 or 12 weeks...
February 15, 2023: Journal of Gastroenterology
https://read.qxmd.com/read/36786863/smoking-history-and-severe-atrophic-gastritis-assessed-by-pepsinogen-are-risk-factors-for-the-prevalence-of-synchronous-gastric-cancers-in-patients-with-gastric-endoscopic-submucosal-dissection-a-multicenter-prospective-cohort-study
#20
JOURNAL ARTICLE
Waku Hatta, Tomoyuki Koike, Sho Asonuma, Hideki Okata, Kaname Uno, Tomoyuki Oikawa, Wataru Iwai, Makoto Yonechi, Daisuke Fukushi, Shoichi Kayaba, Ryosuke Kikuchi, Motoki Ohyauchi, Jun Fushiya, Ryuhei Maejima, Yasuhiko Abe, Masashi Kawamura, Junya Honda, Yutaka Kondo, Naohiro Dairaku, Kazuaki Norita, Kenta Watanabe, Kiichi Takahashi, Hiroharu Echigo, Yasuaki Abe, Hiroyuki Endo, Tomoki Okata, Tatsuya Hoshi, Tomohiro Nakamura, Naoki Nakaya, Katsunori Iijima, Atsushi Masamune
BACKGROUND: No studies have evaluated the relationship between lifestyle and synchronous gastric cancers (SGCs) in patients with endoscopic submucosal dissection (ESD) for early gastric cancers (EGCs). Using data from the Tohoku gastrointestinal (GI) study, we aimed to identify factors associated with SGCs. METHODS: Tohoku GI study is a multicenter prospective cohort study investigating the relationship between lifestyle and metachronous gastric cancers. Patients who had a schedule to undergo ESD for primary EGCs were enrolled...
February 14, 2023: Journal of Gastroenterology
journal
journal
31913
1
2
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.