Mahdiyar Iravani Saadi, Mohsen Nikandish, Zahra Ghahramani, Fatemeh Mardani Valandani, Maryam Ahmadyan, Fakhroddin Hosseini, Zahra Rahimian, Heeva Jalali, Fataneh Tavasolian, Ehsan Nabi Abdolyousefi, Nadiya Kheradmand, Mani Ramzi
BACKGROUND: Acute lymphoblastic leukemia (ALL) is a malignancy that leads to altered blast cell proliferation, survival, and maturation and eventually to the lethal accumulation of leukemic cells. Recently, dysregulated expression of various micro-RNAs (miRNAs) has been reported in hematologic malignancies, especially ALL. Cytomegalovirus infection can induce ALL in otherwise healthy individuals, so a more detailed evaluation of its role in ALL-endemic areas like Iran is required. METHODS: In this cross-sectional study, 70 newly diagnosed adults with ALL were recruited...
June 19, 2023: Journal of the Egyptian National Cancer Institute